Yervoi 5 mg/ml Infusion 10 ml

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹72500

(Inclusive of all Taxes)

₹8700.0 Cashback (12%)

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Non returnable*

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Prescription drug

Whats That

About Yervoi 5 mg/ml Infusion

Yervoi 5 mg/ml Infusion is an anti-cancer medicine used in the treatment of various types of cancers. Cancer is a disease caused by the abnormal growth of cells that divide uncontrollably. This medicine is used in treating metastatic melanoma, advanced renal cell carcinoma in combination with nivolumab, hepatocellular carcinoma in patients who have previously been treated with sorafenib, colorectal cancer, metastatic non-small cell lung cancer, and malignant pleural mesothelioma.

Yervoi 5 mg/ml Infusion contains Ipilimumab, which belongs to the class of CTLA-4 monoclonal antibody. It works by inhibiting the action of a human cytotoxic T-lymphocyte antigen 4 molecule, thereby stopping the abnormal growth of cancer cells.

Yervoi 5 mg/ml Infusion may cause certain side effects such as diarrhoea, decreased appetite, nausea, vomiting, tiredness, itching, rash, headache, fever, decreased weight, and dizziness. Inform your doctor if any of these side effects bother you. Yervoi 5 mg/ml Infusion will be administered by an oncologist with experience in administering chemotherapeutic agents in the hospital setting. Avoid self-administration.

If you are allergic to Yervoi 5 mg/ml Infusion or its components, inform your doctor. Before taking Yervoi 5 mg/ml Infusion, inform your doctor if you have/had liver or kidney disease, autoimmune disorders such as ulcerative colitis, Crohn’s disease, or a history of organ transplants. This medicine is known to cause embryo-fetal toxicity. Hence, it is not recommended for use in pregnancy. If you are breastfeeding, inform your doctor before receiving Yervoi 5 mg/ml Infusion.

Uses of Yervoi 5 mg/ml Infusion

Renal Cell Carcinoma, Hepatocellular carcinoma, Colorectal Cancer, Metastatic Melanoma, metastatic non-small cell lung cancer, Malignant pleural mesothelioma.

Directions for Use

Yervoi 5 mg/ml Infusion will be administered by an oncologist with experience in administering chemotherapeutic agents in the hospital setting. Hence, do not self-administer. Your doctor will decide the dose and duration of the medicine based on the severity and type of cancer.

Medicinal Benefits

Yervoi 5 mg/ml Infusion contains Ipilimumab, which is used in treating different types of cancers. It works by inhibiting the action of a human cytotoxic T-lymphocyte antigen 4 molecule (CTLA-4) that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. In this way, Yervoi 5 mg/ml Infusion stops the body's production, spread and growth of cancerous cells.

Storage

Keep Yervoi 5 mg/ml Infusion out of the sight and reach of children.

Side effects of Yervoi 50mg/10ml Inj

Low Levels Of Lymphocytes (A Type Of White Blood Cells)

Nourish your body with a balanced diet with protein-rich foods like fish, eggs, and beans. Fruits, vegetables, and nuts provide essential vitamins and minerals. If necessary, consider vitamin B12 and folate supplements.
Practice good hygiene to protect yourself from infections. Wash your hands often, stay up-to-date on vaccinations, avoid crowded areas, and take care when handling food, pets, and diapers.
Aim for a good night's sleep, targeting 8 hours of sleep. Find calm through stress-reducing practices like yoga, meditation, or deep breathing. Regular physical activity can also help.
Stay healthy by drinking plenty of water, eating probiotic-rich foods like yoghurt, and limiting processed foods and sugars. Consult your doctor, if you are having difficulties or concerns.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Sudden Feeling Of Heat, Flushed Faced, And Sweat

Always wear loose-fitting clothes suitable for your activity during hot flashes.
Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
Drink plenty of water and stay hydrated.
Stay calm and lower your anxiety by practising yoga or meditation.

Weakness

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Pain

Apply a hot/cold pack to the affected area.
Doing gentle exercises can help cope with pain by stretching muscles.
Get enough sleep. It helps enhance mood and lower pain sensitivity.
Avoid alcohol, smoking and tobacco as they can increase pain.
Follow a well-balanced meal.
Meditation and massages may also help with pain.

Weight Loss

Weight loss without physical activity needs immediate medical attention.
Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
Talk to your dietician and consume food which can maintain ideal weight.

Dehydration

Dehydration would need immediate medical attention if its severe where medical help can save you from crisis.
In case the level of dehydration is from mild to moderate, drink plenty of water for an immediate relief.
Seek a place where the surrounding temperature is less and try to stay away from heat and humidity.
Lie down by keeping a cool and wet towel on your forehead to prevent high temperature in your body to avoid dehydration.
Talk to your medical practitioner and use oral rehydrating salts to replace the lost salts from your body.

Drug Warnings

To treat your condition effectually, continue taking Yervoi 5 mg/ml Infusion for the period that your doctor has prescribed. Yervoi 5 mg/ml Infusion may cause severe immune-mediated adverse reactions (IMAR) such as immune-mediated colitis, hepatitis, nephritis, endocrinopathies, pneumonitis, and dermatologic reactions. It may also cause infusion-related reactions in some patients. Discontinue the treatment if any severe infusion reactions occur. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Caution should be exercised if you have/had liver or kidney disease, any history of organ transplant, gastrointestinal disorders and autoimmune disorders such as ulcerative colitis or Crohn’s disease while receiving Yervoi 5 mg/ml Infusion. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. This medicine is not recommended for use in children below 12 years of age as the safety and efficacy are not established.

Drug-Drug Interactions

IpilimumabApixaban

Severe

IpilimumabFondaparinux

Severe

Drug-Drug Interactions

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IpilimumabApixaban

Severe

How does the drug interact with Yervoi 50mg/10ml Inj:
Combining Yervoi 50mg/10ml Inj and apixaban may raise the risk of stomach bleeding and ulcers.

How to manage the interaction:
Even though there is an interaction between Apixaban and Yervoi 50mg/10ml Inj, they can be taken if a doctor prescribes it. If you experience potential gastrointestinal injury symptoms like abdominal pain, bloating, dizziness, lightheadedness, loss of hunger, nausea, vomiting (especially with either dry or fresh blood that looks like coffee grounds), and red or black stool, you should see a doctor right away. Without consulting a doctor, never stop taking any medication.

IpilimumabFondaparinux

Severe

How does the drug interact with Yervoi 50mg/10ml Inj:
Taking fondaparinux with Yervoi 50mg/10ml Inj can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possibility of interaction between Fondaparinux and Yervoi 50mg/10ml Inj, but it can be taken if prescribed by a doctor. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Physical activity helps strengthen muscles, reduces fatigue, helps in weight loss, and gives strength. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
Eat food rich in antioxidants such as berries, spinach, etc.
Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains, nuts, and seeds.
Avoid smoking and alcohol consumption.
Maintain a healthy weight.

Side Effects of Yervoi 5 mg/ml Infusion

Nausea
Vomiting
Diarrhoea
Loss of appetite
Tiredness
Chest pain
Dizziness
Weakness
Difficulty falling a sleep
Muscle pain
Cough
Headache
Fever
Itching
Rash

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Author Details

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Yervoi 5 mg/ml Infusion work?

Yervoi 5 mg/ml Infusion contains Ipilimumab, which works by inhibiting the action of a human cytotoxic T-lymphocyte antigen-4 (CTLA-4) molecule that causes the multiplication of cancerous cells.

Can Yervoi 5 mg/ml Infusion received by diabetic patients?

It is safe to use Yervoi 5 mg/ml Infusion in patients with diabetes. However, if you are diabetic, inform your doctor before starting the treatment with Yervoi 5 mg/ml Infusion.

Drug-Drug Interactions Checker List

RIVAROXABAN
WARFARIN
HEPARIN
TERIFLUNOMIDE
ADO TRASTUZUMAB EMTANSINE
PEXIDARTINIB

Special Advise

Your doctor may suggest periodic liver function tests, kidney function tests, and lung function tests to monitor the function of the liver, kidney and lungs due to the use of Yervoi 5 mg/ml Infusion.
Using contraceptive pills while using Yervoi 5 mg/ml Infusion to prevent pregnancy is advised.
Thyroid function and adrenocorticotropic hormone levels will be monitored during treatment to avoid any life-threatening side effects.

Disease/Condition Glossary

Renal Cell Carcinoma: Also known as kidney cancer. It is the most common type of cancer seen in adults. This condition occurs when cancer/ malignant cells grow uncontrollably in the kidney and form a tumor. Advanced kidney cancer (metastatic renal cell carcinoma) occurs when the malignant cells spread to other parts of the body. Symptoms include red, orange, or pink-coloured urine due to the presence of blood in the urine.

Hepatocellular carcinoma: Also known as liver cancer. It occurs when the cancer/ malignant cells grow out of control. This infects the liver, destroys the liver cells and affects the ability of the liver to work properly. Symptoms may include abdominal pain, loss of appetite, weight loss, and pale bowel motions.

Colorectal cancer: Also known as colon cancer (growth of cancer cells in the colon) or rectal cancer (cancer cells grow in the rectum area), is a condition in which the cancerous or malignant cells grow out of control in the colon or rectum. Symptoms may include diarrhoea, constipation, bloody stools, change in bowel habits, abdominal discomfort, etc.

Metastatic Malignant Melanoma: Melanoma is a type of skin cancer in which the cancer cells grow in melanocytes. It is mainly caused by harmful UV radiation from the sun. When the cancer cells spread to other parts of the body, it is known as Metastasis. Malignant melanoma is common in fair-skinned and freckled individuals. It results in mole formation, typically on the skin of the face.

Malignant pleural mesothelioma: It is a type of cancer that develops in the mesothelium (a lining that covers the outer surface of organs), predominantly caused by exposure to asbestos. Symptoms of mesothelioma in the lining of the lungs include chest pain, shortness of breath, extreme tiredness, persistent cough, loss of appetite, unexplained weight loss, fever and sweating, particularly at night.

Non-Small Cell Lung Cancer (NSCLC): Lung cancer is defined as an uncontrollable growth of abnormal cells in one or both lungs. These abnormal cells disturb lung cell functions and do not develop into healthy lung tissue. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow. It is mostly seen in persons who smoke. Symptoms may include chest pain, weight loss, hoarseness, and difficulty breathing.