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Composition :

VINCRISTINE-1MG

Manufacturer/Marketer :

Zuvius Lifesciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Z-Cristin 1 mg/ml Injection

Z-Cristin 1 mg/ml Injection belongs to a class of drugs known as 'anti-cancer medication,' primarily used to treat various types of cancer. It is used to treat cancer of the breast, pancreas, kidney, blood, bone, lung. Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are more than 100 types of cancer, including blood cancer, lung cancer, breast cancer.

Z-Cristin 1 mg/ml Injection contains Vincristine, which is primarily used to treat cancer. It works by blocking the replication of DNA (genetic material) in the cancer cells. Hence, this stops the further growth and multiplication of the cancer cells. 

Take Z-Cristin 1 mg/ml Injection as prescribed by your doctor. You are advised to take Z-Cristin 1 mg/ml Injection for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience hair loss, constipation, headache, peripheral neuropathy (tingling and numbness of feet and hand), stomach cramps, feeling tired or weak, back, bone, joint, or muscle pain, mouth irritation, or mouth sores. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently. 

Do not take Z-Cristin 1 mg/ml Injection if you are allergic to Z-Cristin 1 mg/ml Injection or any of its ingredients. Z-Cristin 1 mg/ml Injection is a pregnancy category D drug, so it should not be used in pregnant women or if you are planning for pregnancy as Z-Cristin 1 mg/ml Injection causes serious congenital disabilities. You should use an effective way for birth control to avoid pregnancy (both men and women) while taking Z-Cristin 1 mg/ml Injection. Avoid consuming alcohol along with Z-Cristin 1 mg/ml Injection as it could lead to increased dizziness. Z-Cristin 1 mg/ml Injection may make you more susceptible to infections; consult your doctor if you develop any signs of fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. 

Uses of Z-Cristin 1 mg/ml Injection

Various types of cancer

Directions for Use

Z-Cristin 1 mg/ml Injection comes in injection form. So, it should be administered by a doctor or trained professional at a hospital. Never self administer.

Medicinal Benefits

Z-Cristin 1 mg/ml Injection contains Vincristine, an anti-cancer medicine used to treat various types of cancer. It is used to treat cancers of the blood (leukemia or lymphomas), breast, head and neck or lung. It may be used to treat multiple myeloma (a cancer of plasma cells), and it may also be used in the treatment of some cancers in children. It is also used in a blood disorder known as idiopathic thrombocytopenic purpura (ITP) after another medication has become unsuccessful in treating it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Z-Cristin 1 mg/ml Injection

  • Constipation
  • Headache
  • Hair loss
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Stomach cramps
  • Feeling tired or weak
  • Mouth irritation or mouth sores
  • Back, bone, joint, or muscle pain

Drug Warnings

Do not take Z-Cristin 1 mg/ml Injection if you are allergic to Z-Cristin 1 mg/ml Injection or any of its ingredients. You should use an effective way for birth control to avoid pregnancy (both men and women) while taking Z-Cristin 1 mg/ml Injection. Do not take Z-Cristin 1 mg/ml Injection if you are pregnant or planning for pregnancy as Z-Cristin 1 mg/ml Injection causes serious congenital disabilities. Z-Cristin 1 mg/ml Injection should not be taken by breastfeeding mothers as it is not known whether it passes through breast milk or not. Talk to your doctor before taking Z-Cristin 1 mg/ml Injection if you have/had liver or kidney problems, ulceration in stomach or bowels, poor general condition, received any vaccinations or if are due to have any, diabetes mellitus treated with insulin. Z-Cristin 1 mg/ml Injection causes dizziness and drowsiness, so drive with caution. Z-Cristin 1 mg/ml Injection should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Z-Cristin 1 mg/ml Injection as it could lead to increased dizziness. Z-Cristin 1 mg/ml Injection may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. 

Drug-Drug Interactions

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VincristineCeritinib
Severe
VincristineKetoconazole
Severe

Drug-Drug Interactions

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VincristineCeritinib
Severe
How does the drug interact with Z-Cristin 1 mg/ml Injection:
Taking Z-Cristin 1 mg/ml Injection with Ceritinib significantly increase the blood levels and effects of Z-Cristin 1 mg/ml Injection which may increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Z-Cristin 1 mg/ml Injection and Ceritinib, but it can be taken if prescribed by a doctor. If you experience any of these symptoms constipation, abdominal pain or bloating, difficulty urinating, numbness or tingling in hands and feet, muscle weakness, difficulty walking, hearing loss, fits, unusual or excessive bleeding, easy bruising, paleness, weakness, fainting, infection, fever, chills, sore throat, call a doctor. Do not stop using any medications without talking to a doctor.
VincristineKetoconazole
Severe
How does the drug interact with Z-Cristin 1 mg/ml Injection:
When Z-Cristin 1 mg/ml Injection is taken with Ketoconazole, it can increase the blood levels of Z-Cristin 1 mg/ml Injection which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Z-Cristin 1 mg/ml Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience constipation, stomach pain or bloating, difficulty urinating, numbness or tingling in hands and feet, muscle weakness, difficulty walking, hearing loss, seizures(fits), unexpected or excessive bleeding, easy bruising, paleness, fatigue, fainting, infection, fever, chills, sore throat, or other flu-like symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
VincristineRitonavir
Severe
How does the drug interact with Z-Cristin 1 mg/ml Injection:
Taking Ritonavir and Z-Cristin 1 mg/ml Injection may significantly increase the blood levels and effects of Z-Cristin 1 mg/ml Injection.

How to manage the interaction:
Although there is a possible interaction between Z-Cristin 1 mg/ml Injection and Ritonavir, you can take these medicines together if prescribed by your doctor. However, if you experience constipation, abdominal pain or bloating, difficulty urinating, numbness or tingling in hands and feet, muscle weakness, difficulty walking, hearing loss, fits, unusual or excessive bleeding, easy bruising, paleness, tiredness, fainting, infection, fever, chills, sore throat contact a doctor. Do not stop using any medications without a doctor's advice.
VincristineTofacitinib
Severe
How does the drug interact with Z-Cristin 1 mg/ml Injection:
Taking Tofacitinib with Z-Cristin 1 mg/ml Injection may increase the risk of infection.

How to manage the interaction:
Co-administration of Z-Cristin 1 mg/ml Injection with Tofacitinib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
VincristineClozapine
Severe
How does the drug interact with Z-Cristin 1 mg/ml Injection:
When Z-Cristin 1 mg/ml Injection and Clozapine are taken together, can increase the effect of Z-Cristin 1 mg/ml Injection.

How to manage the interaction:
Taking Clozapine with Z-Cristin 1 mg/ml Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact your doctor right away. They may be able to recommend other options for you that won't cause any problems. Don't worry, there are solutions available to help you feel better. Do not stop using any medications without first talking to your doctor.
VincristineVoriconazole
Severe
How does the drug interact with Z-Cristin 1 mg/ml Injection:
Using Z-Cristin 1 mg/ml Injection together with voriconazole may significantly increase the blood levels and effects of Z-Cristin 1 mg/ml Injection.

How to manage the interaction:
Although taking Voriconazole and Z-Cristin 1 mg/ml Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience abdominal pain, difficulty urinating, hearing loss, fever contact a doctor right away. Do not discontinue any medications without consulting a doctor.
VincristinePosaconazole
Severe
How does the drug interact with Z-Cristin 1 mg/ml Injection:
Coadministration of posaconazole and Z-Cristin 1 mg/ml Injection can raise the levels of Z-Cristin 1 mg/ml Injection in the blood and increase its effects.

How to manage the interaction:
Although using Posaconazole and Z-Cristin 1 mg/ml Injection together can result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience constipation, abdominal pain or bloating, difficulty urinating, numbness or tingling in hands and feet, muscle weakness, difficulty walking, hearing loss, fatigue, fainting, fever, chills, or sore throat. Do not stop taking any medications without consulting a doctor.
VincristineInfliximab
Severe
How does the drug interact with Z-Cristin 1 mg/ml Injection:
When Z-Cristin 1 mg/ml Injection is taken with Infliximab, it can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Infliximab and Z-Cristin 1 mg/ml Injection, but it can be taken if prescribed by a doctor. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VincristineThalidomide
Severe
How does the drug interact with Z-Cristin 1 mg/ml Injection:
Taking thalidomide together with Z-Cristin 1 mg/ml Injection may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Z-Cristin 1 mg/ml Injection together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
VincristineEtanercept
Severe
How does the drug interact with Z-Cristin 1 mg/ml Injection:
When Etanercept is used with Z-Cristin 1 mg/ml Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Etanercept and Z-Cristin 1 mg/ml Injection, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, and high fiber content. Also, eat small and frequent meals for a speedy recovery.
  • Avoid smoking and alcohol consumption. Also, avoid high fat and cholesterol diet.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Z-Cristin 1 mg/ml Injection Substitute

Substitutes safety advice
  • Vincihal 1 mg Injection 1 ml

    by Others

    54.00per tablet
  • Vincristine Gls 1 mg Injection 1's

    by Others

    54.00per tablet
  • Alcrist 1mg Injection

    by Others

    46.74per tablet
  • Biocristin AQ 1 mg Injection 1 ml

    by Others

    45.19per tablet
  • Cytocristin 1mg Injection

    by Others

    43.82per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Z-Cristin 1 mg/ml Injection contains Vincristine, which works by blocking DNA replication (genetic material) in the cancer cells. Hence, this stops the further growth and multiplication of the cancer cells. 

Z-Cristin 1 mg/ml Injection if not administered properly, and if it leaks from the vein, it may cause tissue damage. So, if you see any redness, pain, swelling, burning, skin sores or leaking of fluid from where the drug is going into your body, please tell your nurse.

The most common side effects of Z-Cristin 1 mg/ml Injection are hair loss, constipation, headache, peripheral neuropathy (tingling and numbness of feet and hand), stomach cramps, feeling tired or weak, back, bone, joint or muscle pain, mouth irritation or mouth sores​​​​​​​. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently. 

Z-Cristin 1 mg/ml Injection is a vesicant (irritant) and can damage the tissues and blood vessels if it is not administered correctly, which can be fatal. So, it should be given by a trained professional in the hospital.

Yes, Z-Cristin 1 mg/ml Injection is a cytotoxic (toxic to living cells) medicine. So, it is advised to be very cautious while taking Z-Cristin 1 mg/ml Injection.

Drug-Drug Interactions Checker List

  • ISONIAZID
  • DACTINOMYCIN
  • ITRACONAZOLE
  • FLUCONAZOLE
  • ASPARAGINASE

Special Advise

  • Regularly monitor your blood cell count, platelet count and liver function.
  • If you see any redness, pain, swelling, burning, skin sores, or leaking of fluid from where the drug is going into your body, please tell your nurse as this could mean that Z-Cristin 1 mg/ml Injection is not being administered properly which could lead to tissue damage.

Disease/Condition Glossary

Cancer: It is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer, namely benign (localized) and metastatic (spread to the whole body). There are more than 100 types of cancer, including blood cancer, lung cancer, breast cancer. Cancer growth can be prevented by chemotherapy, radiation, stem cell therapy and by doing surgical excision.

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