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  1. Home
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  3. Zam-MT 0.5 Tablet 10's

Not for online sale
Zam-MT 0.5 Tablet 10's, Pack of 10 TABLETS
Written By ,
Reviewed By Sunny S , MBBS
Non returnable*
Know More
COD available

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Whats That

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Composition :

ALPRAZOLAM-0.5MG + MELATONIN-3MG

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zam-MT 0.5 Tablet

Zam-MT 0.5 Tablet belongs to a class of medication called sedatives and hypnotics, primarily used to treat sleeplessness (insomnia). Besides this, it also helps to provide a calming effect on anxiety disorder and panic disorder. Insomnia is a sleeping disorder in which a person finds difficulty in falling asleep or staying asleep. Due to anxiety and panic disorder, a person cannot sleep due to disturbances in their circadian cycle and hormonal imbalance in the brain like melatonin. 

Zam-MT 0.5 Tablet is a combination of two medicines: Alprazolam and Melatonin, which helps a person fall asleep faster and stay asleep during the night. Alprazolam is a benzodiazepine (BZD) that increases the activity of a chemical messenger in the brain known as GABA, reducing the abnormal and overactivity of brain cells (neurons), which in turn relaxes the brain and promotes sleep. On the other hand, Melatonin is a natural hormone that activates the ON-OFF mechanism of a person's sleeping-waking cycle (circadian cycle), thereby inducing sleep during the nighttime. 

Take Zam-MT 0.5 Tablet with or without food and swallow whole with a glass of water. Do not break, crush, or chew it. Your doctor will advise you how often you take Zam-MT 0.5 Tablet based on your medical condition. The most common side effects of Zam-MT 0.5 Tablet include drowsiness, tiredness, headache, depressed mood, daytime drowsiness, stomach pain, and dizziness. Most of these side effects of Zam-MT 0.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Tell your doctor if you have an ongoing medical condition, including depression, diabetes, an autoimmune disorder, or high blood pressure. If you are known to be allergic to Zam-MT 0.5 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor before taking Zam-MT 0.5 Tablet . Zam-MT 0.5 Tablet should be used with caution in elderly patients as there is an increased risk of adverse reactions such as dizziness, muscle weakness, and drowsiness.

Uses of Zam-MT 0.5 Tablet

Insomnia (sleeplessness) 

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Zam-MT 0.5 Tablet belongs to a class of sedatives and hypnotics, primarily used to treat insomnia (difficulty in falling asleep or staying asleep). Zam-MT 0.5 Tablet is a combination of two medicines: 'Alprazolam' and  'Melatonin', which helps a person fall asleep faster and stay asleep during the night, which has been disturbed due to anxiety or panic disorder. Zam-MT 0.5 Tablet helps relax the brain's exciting chemicals (GABA), allowing a person to sleep easily and stay asleep during the whole night without any disturbance.  

Storage

Keep Zam-MT 0.5 Tablet out of the sight and reach of children.

Drug Warnings

Before your doctor prescribes your Zam-MT 0.5 Tablet , you should tell your doctor if you have allergies or not. With it, also tell if you are pregnant or breastfeeding as the use of this medication is restricted to be used in pregnancy and breastfeeding. Elderly people are more responsive to the side effects of the drug, so they should tell every product, including the herbal ones to their doctor so that doctor can decide the dosage for them. Inform your doctor about myasthenia gravis (muscle weakness), drug addiction, chronic pulmonary insufficiency, narrow-angle glaucoma, and kidney/liver problem before taking Zam-MT 0.5 Tablet . Do not take Zam-MT 0.5 Tablet with opioids as it may cause breathing problems, drowsiness and coma.

Drug-Drug Interactions

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AlprazolamDelavirdine
Critical
AlprazolamIndinavir
Critical

Drug-Drug Interactions

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AlprazolamDelavirdine
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
The combination of Zam-MT 0.5 Tablet and Delavirdine may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.5 Tablet and Delavirdine, it can be used if prescribed by a doctor. Consult a doctor if you have sleepiness, dizziness, confusion, or weak or rapid breathing over a long duration of time. Do not discontinue any medications without consulting a doctor.
AlprazolamIndinavir
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
The combination of Zam-MT 0.5 Tablet and Indinavir may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.5 Tablet and Indinavir, it can be used if prescribed by a doctor. Consult a doctor if you have drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamClarithromycin
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
The combination of Zam-MT 0.5 Tablet and clarithromycin may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.5 Tablet and clarithromycin, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.
AlprazolamCobicistat
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
Co-administration of Zam-MT 0.5 Tablet with Cobicistat may considerably increase the blood levels and effects of Zam-MT 0.5 Tablet.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.5 Tablet and Cobicistat, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamItraconazole
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
Zam-MT 0.5 Tablet's blood levels may be significantly raised when combined with itraconazole.

How to manage the interaction:
Although combining Zam-MT 0.5 Tablet and Itraconazole may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
AlprazolamKetoconazole
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
Co-administration of Zam-MT 0.5 Tablet with Ketoconazole may considerably increase the blood levels of Zam-MT 0.5 Tablet, which may result in side effects.

How to manage the interaction:
Although there is an interaction between Zam-MT 0.5 Tablet and Ketoconazole, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamCeritinib
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
Co-administration of Zam-MT 0.5 Tablet with Ceritinib may considerably increase the blood levels and effects of Zam-MT 0.5 Tablet.

How to manage the interaction:
Although there is a interaction between Zam-MT 0.5 Tablet and Ceritinib, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamSodium oxybate
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
Co-administration of Zam-MT 0.5 Tablet with Sodium Oxybate may increase Sodium Oxybate's adverse effects (respiratory depression, low blood pressure, fainting).

How to manage the interaction:
Although the combination of Zam-MT 0.5 Tablet and sodium oxybate may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you suffer any of the following symptoms: breathing difficulties, low blood pressure, being severely drowsy, or fainting. Avoid driving or operating hazardous machinery or performing other hazardous activities for at least 6 hours after taking a dose. Do not discontinue any medications without consulting a doctor.
AlprazolamCabozantinib
Severe
How does the drug interact with Zam-MT 0.5 Tablet:
Concomitant use of Alfuzosin with Cabozantinib can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Alfuzosin with Cabozantinib can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, difficulty in breathing, or chest pain. Do not discontinue any medications without consulting a doctor.
AlprazolamBuprenorphine
Severe
How does the drug interact with Zam-MT 0.5 Tablet:
Using Zam-MT 0.5 Tablet together with Buprenorphine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although the combination of Zam-MT 0.5 Tablet and Buprenorphine may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you have any symptoms such as dizziness, drowsiness, difficulty concentrating, or impairment in judgment, reaction speed, or control of movements. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keeping a fixed time to go to bed and wake up consistently every day helps maintain a better sleeping and waking plan.
  • Engage yourself in workouts, dancing, and walking that help promote calmness in the body so that you can enjoy a good night's sleep.
  • Taking naps in a day can make it harder to fall asleep at night, so one should try to limit a nap to no more than half an hour and don't nap after 2 p.m. 
  • Limit caffeine and alcohol consumption as it will not let you sleep and causes frequent urination.
  • Avoid large, heavy meals before bed. One can have a light snack that helps to avoid heartburn.
  • Avoid consumption of alcohol as it may increase drowsiness.
  • Take less liquid before bedtime so that you won't have to urinate as often. One must keep their worries and planning aside and enjoy a warm bath or a massage before bedtime. It will help in having a good night's relaxing sleep.

Habit Forming

Yes

Therapeutic Class

SEDATIVE-HYPNOTIC DRUGS

Zam-MT 0.5 Tablet Substitute

Substitutes safety advice

Product Substitutes

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Zam-MT 0.5 Tablet is a combination of two medicines: Alprazolam and Melatonin, which helps a person fall asleep faster and stay asleep during the night. Alprazolam is a benzodiazepine (BZD) that increases the activity of a chemical messenger in the brain known as GABA, reducing the abnormal and overactivity of brain cells (neurons), which in turn relaxes the brain and promotes sleep. On the other hand, Melatonin is a natural hormone that activates the ON-OFF mechanism of a person's sleeping-waking cycle (circadian cycle), thereby inducing sleep during the nighttime.

It is advised not to take Zam-MT 0.5 Tablet if you have a bleeding disorder as taking this medicine may worsen the medical condition. The use of Zam-MT 0.5 Tablet is restricted in patients dealing with diabetes and depression.

It is advised not to stop taking this medicine by yourself. If you are noticing an improvement in their condition, then you should first consult with their doctor. The doctor will gradually reduce the dose and then stop it to avoid withdrawal effects

It is suggested not to indulge in any heavy exercise like running or put up heavyweights as it can make you active and wake for a long time. However, you can practice some mindful activities like meditation to make yourself relax and sleep properly. Doing heavy workouts before bed increases blood circulation and body temperature of the body and creates difficulty sleeping. Your bedroom should be dark and should be mend for only sleep.

It has been reported in some patients that Zam-MT 0.5 Tablet may cause drowsiness. Therefore, it is recommended to avoid driving or any other activities that require mental alertness after taking Zam-MT 0.5 Tablet .

Yes, it has been observed in some persons that Zam-MT 0.5 Tablet may cause mental or physical dependence if used for a prolonged time. Therefore, take Zam-MT 0.5 Tablet only in dose and duration as advised by your doctor.

Zam-MT 0.5 Tablet is habit-forming and should be used for a short duration in adults and should only be taken after discussing it with doctors. However, taking it for a longer time may cause extreme drowsiness the next day. Thus, one should always take this medication within the prescribed time limit.

Drug-Drug Interactions Checker List

  • FLUOXETINE
  • NEFAZODONE
  • ERYTHROMYCIN
  • RIFABUTIN
  • KETOCONAZOLE
  • MORPHINE
  • CODEINE
  • DIHYDROCODEINE
  • BUPRENORPHINE

Special Advise

  • Do not take Zam-MT 0.5 Tablet for a prolonged time as it may lead to mental or physical dependence on Zam-MT 0.5 Tablet .

Disease/Condition Glossary

Insomnia: It is a sleep disorder that affects many people in the world. Persons dealing with insomnia don't feel energetic or refreshed after waking up from a long night's sleep. It is of two types: Acute and chronic insomnia. Acute insomnia may last from one night to a few weeks and occurs due to stress or life changes. Chronic insomnia may last from more than 3 nights per week to more than 3 months, making a person either wake up the whole night or cause trouble in falling asleep. Causes of insomnia include stress, physical pain, any traumatic event, psychological issues including depression, diabetes, side effects of certain medications, and many more. Signs and symptoms of insomnia include fatigue, irritability, trouble concentrating on tasks, and mood changes.

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