Zandron 150 mg Tablet 10's

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹18500

(Inclusive of all Taxes)

₹2775.0 Cashback (15%)

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Whats That

About Zandron 150 mg Tablet

Zandron 150 mg Tablet is an anti-androgen medicine used in the treatment of prostate cancer. Prostate cancer is a condition that occurs when the prostate gland cells increase abnormally. Symptoms may include difficulty in urinating, pain, numbness, etc. It is used in the treatment of metastatic prostate cancer in combination with surgical castration.

Zandron 150 mg Tablet contains Nilutamide, which belongs to the class of androgen inhibitors. It works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

Zandron 150 mg Tablet may cause certain side effects such as nausea, dizziness, headache, diarrhoea, muscle weakness, confusion, hot flushes, loss of appetite and difficulty breathing. These side effects usually disappear without any medical attention. Take Zandron 150 mg Tablet as prescribed by your doctor.

Zandron 150 mg Tablet should be avoided if you are allergic to it. Inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, and respiratory problems before taking Zandron 150 mg Tablet . Zandron 150 mg Tablet is not recommended for use in children as the safety and efficacy of this medicine are not established. This medicine is only intended for male patients.

Uses of Zandron 150 mg Tablet

Prostate Cancer

Directions for Use

Zandron 150 mg Tablet should be taken as advised by your doctor. It can be taken with or without food. Swallow the medicine as a whole with a glass of water. Do not chew, crush or break the medicine. It is advised not to take more than the recommended dose of medicine.

Medicinal Benefits

Zandron 150 mg Tablet contains Nilutamide, which belongs to the class of androgen inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. Zandron 150 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. It is mainly intended for use in men only.

Storage

Keep Zandron 150 mg Tablet out of the sight and reach of children.

Side effects of Zandron 150 mg Tablet

Shrinking Of The Testicles

Zinc is essential for testosterone production, so include zinc-rich foods like oysters, nuts, seeds, and red meat in your diet.
Excessive alcohol intake is a significant contributor to testicular atrophy, so reduce or eliminate alcohol from your diet.
Engage in moderate-intensity exercise most days of the week to improve blood circulation and hormone production.
Wear loose-fitting underwear and pants to prevent pressure on the testicles.
Avoid prolonged exposure to hot environments like saunas or hot baths, as high temperatures can negatively impact sperm production.
If you notice any unusual changes in your testicles or have concerns about your testicular health, consult a doctor for a thorough evaluation.

Shortness Of Breath

Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):

Tell your doctor immediately if you experience shortness of breath after taking medication.
Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Changed Response To Darkness

Sudden Feeling Of Heat, Flushed Faced, And Sweat

Always wear loose-fitting clothes suitable for your activity during hot flashes.
Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
Drink plenty of water and stay hydrated.
Stay calm and lower your anxiety by practising yoga or meditation.

Trouble Falling/ Staying Asleep

Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:

Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
Try relaxing techniques like deep breathing, mindfulness meditation and any others.
Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

Enlarged Breasts In Males

Regular activity including cardio and weightlifting can help in weight loss and breast tissue reduction.
Limit alcohol intake to lower your chances of gynecomastia and hormonal changes.
Eat a balanced diet and avoid foods high in estrogen-like compounds.
Follow your doctor's instructions take medication consistently to reduce breast enlargement and do not stop taking medication on your own.

General Feeling Of Discomfort Or Unease

Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:

If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
Inform your doctor about the medication you're taking and the symptoms you're experiencing.
Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.

Drug Warnings

Zandron 150 mg Tablet should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical and medication history beforehand to rule out any side effects. Inform your doctor if you have/had any conditions like liver/kidney disease, cardiovascular disease, or taking any other medicines before taking Zandron 150 mg Tablet as it may cause serious side effects. Zandron 150 mg Tablet is not recommended for use in children as the safety and efficacy of this medicine are not established. Zandron 150 mg Tablet may cause intestinal pneumonitis hepatitis.

Drug-Drug Interactions

NilutamideZiprasidone

Critical

NilutamideAmiodarone

Severe

Drug-Drug Interactions

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NilutamideZiprasidone

Critical

How does the drug interact with Zandron 150 mg Tablet:
Using ziprasidone together with Zandron 150 mg Tablet can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Ziprasidone with Zandron 150 mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

NilutamideAmiodarone

Severe

How does the drug interact with Zandron 150 mg Tablet:
Coadministration of Amiodarone with Zandron 150 mg Tablet that can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Amiodarone with Zandron 150 mg Tablet together is not recommended as it can result in an interaction, it can be taken only if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, palpitations, or rapid heartbeat. Do not discontinue any medications without consulting a doctor.

NilutamideClozapine

Severe

How does the drug interact with Zandron 150 mg Tablet:
When Zandron 150 mg Tablet and Clozapine are taken together, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Zandron 150 mg Tablet with Clozapine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: sudden dizziness, feeling lightheaded, fainting, difficulty breathing, or heart palpitations. Do not stop using any medications without a doctor's advice.

NilutamideMoxifloxacin

Severe

How does the drug interact with Zandron 150 mg Tablet:
Using Moxifloxacin together with Zandron 150 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Moxifloxacin and Zandron 150 mg Tablet, but it can be taken if prescribed by a doctor. If you experience fast or irregular heartbeat, dizziness, difficulty breathing - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.

NilutamideDisopyramide

Severe

How does the drug interact with Zandron 150 mg Tablet:
The combined use of Zandron 150 mg Tablet and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Zandron 150 mg Tablet and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

NilutamideHaloperidol

Severe

How does the drug interact with Zandron 150 mg Tablet:
Co-administration of Zandron 150 mg Tablet and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zandron 150 mg Tablet and Haloperidol can lead to an interaction, it can be taken when advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

NilutamideSotalol

Severe

How does the drug interact with Zandron 150 mg Tablet:
Using sotalol together with Zandron 150 mg Tablet can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Zandron 150 mg Tablet, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.

NilutamideCeritinib

Severe

How does the drug interact with Zandron 150 mg Tablet:
Taking ceritinib with Zandron 150 mg Tablet can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Co-administration of Ceritinib with Zandron 150 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience severe or long-lasting diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, having trouble breathing, or experiencing heart palpitations contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Try to take vegetables like cauliflower, cabbage, broccoli, spinach and kale. This food slows the growth of prostate cancer and even reduces the risk of prostate cancer.
It is advised to consume fewer dairy products as these foods may increase the risk of prostate cancer.
Physical activity helps in strengthening muscles, reduces fatigue, helps in weight loss and gives strength.
Maintain a healthy weight by doing regular simple exercises and yoga.
Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
Avoid including high amounts of red meat in your diet. When meat is cooked, it may increase the risk of developing prostate cancer.

Side Effects of Zandron 150 mg Tablet

Dizziness
Headache
Diarrhoea
Muscle Weakness
Confusion
Hot Flushes
Loss of Appetite
Constipation
Difficulty breathing

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Author Details

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:50 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Zandron 150 mg Tablet work?

Zandron 150 mg Tablet contains Nilutamide, which works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

Can I stop taking Zandron 150 mg Tablet when I feel better?

No, do not stop taking Zandron 150 mg Tablet without consulting your doctor. It is recommended to take this medicine for the entire prescribed duration, even when symptoms improve or resolve.

What if I miss a dose of Zandron 150 mg Tablet ?

Take Zandron 150 mg Tablet as advised by your doctor. However, if you forget or miss any dose of Zandron 150 mg Tablet , take it as soon as you remember unless it is time for your next dose. But do not double the dose.

Drug-Drug Interactions Checker List

PHENYTOIN
PHENOBARBITAL
ITRACONAZOLE
KETOCONAZOLE

Special Advise

Zandron 150 mg Tablet is not recommended for use in patients suffering from severe hepatotoxicity and renal toxicity.
This medicine may cause laboratory abnormalities like elevated alkaline phosphatase and hypokalemia.
Regular monitoring of liver and kidney functioning is recommended, with liver/kidney function tests recommended during Zandron 150 mg Tablet usage.

Disease/Condition Glossary

Prostate cancer: The prostate gland is a small walnut-sized gland present under the bladder which is responsible for the production of seminal fluid. Prostate cancer is a carcinogenic condition that occurs when the cells of the prostate gland increase out of control. The main cause of this condition is unknown. However, a few underlying reasons that increase the risk for this condition include age, family history, ethnic group, genetic factors, obesity, etc.