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Composition :

OFLOXACIN-100MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zanocin 100 Solution

Zanocin 100 Solution contains a class of antibiotics known as fluoroquinolones, primarily used to treat infections caused by bacteria including pneumonia, gonorrhoea (a sexually transmitted disease), typhoid fever, infectious diarrhoea, and infections of the skin, eye/ear, bone, joint, abdomen, and prostate (male reproductive gland). A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. 

Zanocin 100 Solution contains antibacterial Ofloxacin, which helps in treating and preventing a wide range of bacterial infections. It is bactericidal and works by killing bacteria that cause infections.  It inhibits the repairing of bacterial cells and kills the bacteria, thereby preventing the further spread of the infection. Zanocin 100 Solution is a broad-spectrum antibiotic against most Gram-negative bacteria, many Gram-positive bacteria and some anaerobes bacteria (that live without oxygen).

Zanocin 100 Solution should be taken in the dose and duration as advised by your doctor. It is advised to take with food and be taken at a fixed time to achieve maximum effect. Do not take Zanocin 100 Solution with dairy products as it may lower its efficacy. You may experience sleep problems, headache, dizziness, nausea, vomiting, diarrhoea, itching, external genital itching in women, vaginal inflammation (vaginitis) and taste changes in some cases. Most of these side effects of Zanocin 100 Solution do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. If you experience any allergic reaction symptoms such as rashes, itching, swelling, or shortness of breath, immediately contact the doctor.

Inform your doctor if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Inform your doctor if you are planning to get pregnant, are pregnant, or breastfeeding. Use of Zanocin 100 Solution is associated with an increased risk of tendinitis and tendon (tough tissue that connects muscle to bone) rupture in all ages. People taking Zanocin 100 Solution who are over 60 years are at high risk, especially those who are taking any anti-allergic medicines like corticosteroid drugs. Zanocin 100 Solution is contraindicated in people with kidney/heart diseases, and for those who have had lung transplant should its use is not recommended.

Uses of Zanocin 100 Solution

Bacterial Infections

Directions for Use

Tablet: Take it with or without food (excluding dairy products). Swallow the tablet with a glass of water. Do not break, crush or chew it.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Zanocin 100 Solution contains the antibiotic Ofloxacin, which helps in treating and preventing a wide range of bacterial infections caused by most Gram-negative bacteria, many Gram-positive bacteria, and some anaerobes bacteria (that live without oxygen). It is bactericidal in nature and works by killing bacteria that cause infections by prevents the formation of the cell wall required for living. It also inhibits the repair of bacterial cells. Altogether it kills the bacteria. Zanocin 100 Solution has the advantage of good penetration in most deep tissues and body fluid. Hence, it is also suitable for the treatment of deep tissue and bone bacterial infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zanocin 100 Solution

  • Tendon rupture
  • Arthralgia (joint pain)
  • Sleep problems
  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Itching
  • External genital itching in women
  • Vaginal inflammation (vaginitis)
  • Taste changes

Drug Warnings

Do not take Zanocin 100 Solution if you are allergic or have had a severe reaction to ofloxacin or any other quinolone or fluoroquinolone antibiotics such as delafloxacin, gemifloxacin, levofloxacin, moxifloxacin, and ciprofloxacin. Taking Zanocin 100 Solution may increase the chances of developing tendinitis (swelling of a fibrous tissue that connects a bone to a muscle) or have a tendon rupture (tearing of a fibrous tissue that connects a bone to a muscle). Inform your doctor if you have or have ever had a kidney, heart, or lung transplant, kidney disease, a joint or tendon disorder such as rheumatoid arthritis (an autoimmune disorder of joints causing pain, swelling, and loss of function), seizures (fits), epilepsy or if you participate in regular physical activity. Taking Zanocin 100 Solution may worsen muscle weakness in people with myasthenia gravis (a nervous system disorder that causes muscle weakness) and cause severe difficulty breathing or death. Dairy products should be avoided along with Zanocin 100 Solution. And also, exposure to sunlight should be avoided while taking Zanocin 100 Solution as it may cause increased phototoxicity or photosensitivity. Patients with epilepsy and irregular heartbeat (QT prolongation) should tell their doctor before taking Zanocin 100 Solution.

Drug-Drug Interactions

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OfloxacinSotalol
Critical
OfloxacinHalofantrine
Critical

Drug-Drug Interactions

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OfloxacinSotalol
Critical
How does the drug interact with Zanocin 100 Solution 50 ml:
Coadministration of Zanocin 100 Solution 50 ml with Sotalol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zanocin 100 Solution 50 ml with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor. Do not discontinue any medications without consulting a doctor.
OfloxacinHalofantrine
Critical
How does the drug interact with Zanocin 100 Solution 50 ml:
Using halofantrine together with Zanocin 100 Solution 50 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Zanocin 100 Solution 50 ml with Halofantrine can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinDisopyramide
Critical
How does the drug interact with Zanocin 100 Solution 50 ml:
Coadministration of Zanocin 100 Solution 50 ml with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Zanocin 100 Solution 50 ml with Disopyramide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinSaquinavir
Critical
How does the drug interact with Zanocin 100 Solution 50 ml:
Coadministration of Zanocin 100 Solution 50 ml with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zanocin 100 Solution 50 ml with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinZiprasidone
Critical
How does the drug interact with Zanocin 100 Solution 50 ml:
Coadministration of Zanocin 100 Solution 50 ml with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Zanocin 100 Solution 50 ml with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinPimozide
Critical
How does the drug interact with Zanocin 100 Solution 50 ml:
Coadministration of Zanocin 100 Solution 50 ml with Pimozide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zanocin 100 Solution 50 ml with Pimozide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinAmiodarone
Critical
How does the drug interact with Zanocin 100 Solution 50 ml:
The combination of Amiodarone and Zanocin 100 Solution 50 ml may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone and Zanocin 100 Solution 50 ml interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.
OfloxacinMesoridazine
Critical
How does the drug interact with Zanocin 100 Solution 50 ml:
Using Mesoridazine together with Zanocin 100 Solution 50 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Zanocin 100 Solution 50 ml is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OfloxacinDronedarone
Critical
How does the drug interact with Zanocin 100 Solution 50 ml:
Coadministration of Zanocin 100 Solution 50 ml with Dronedarone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Zanocin 100 Solution 50 ml with Dronedarone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OfloxacinQuinidine
Critical
How does the drug interact with Zanocin 100 Solution 50 ml:
Coadministration of Zanocin 100 Solution 50 ml with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zanocin 100 Solution 50 ml with Quinidine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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OFLOXACIN-100MGVitamin B complex foods, Vitamin B12 rich foods
Moderate

Drug-Food Interactions

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OFLOXACIN-100MGVitamin B complex foods, Vitamin B12 rich foods
Moderate
Common Foods to Avoid:
Avocado, Beetroot, Cereals, Cheese, Chicken, Black Beans, Eggs, Clams, Chickpea, Whole Grains, Shellfish, Spinach, Salmon, Red Meat, Oysters, Potatoes, Kidney Beans, Mackerel, Milk, Kale, Tuna, Yogurt, Liver, Low-Fat Milk, Trout, Fortified Breakfast Cereal, Fish, Beef

How to manage the interaction:
Zanocin 100 Solution 50 ml and a multivitamin with minerals should not be taken together orally. Products containing magnesium, aluminium, calcium, iron, or other minerals may decrease the effects of Zanocin 100 Solution 50 ml. If at all possible, avoid taking multivitamins containing minerals while receiving Zanocin 100 Solution 50 ml treatment. Do not discontinue any medications without first consulting your doctor.

Diet & Lifestyle Advise

  • Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola, or chocolate. Zanocin 100 Solution may increase nervousness, sleeplessness, and anxiety caused by caffeine.
  • Probiotics should be taken after taking the full course of Zanocin 100 Solution to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria. 
  • Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet. Make sure you drink plenty of water or other fluids every day while you are taking Zanocin 100 Solution.
  • Avoid alcoholic beverages with Zanocin 100 Solution as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Zanocin 100 Solution in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Zanocin 100 Solution Substitute

Substitutes safety advice
  • Oflox 100 Rediuse Oral Suspension 60 ml

    by Others

    2.69per tablet
  • Zanocin 100 Tablet 10's

    by Others

    6.39per tablet
  • Oflomac Forte Oral Solution 60 ml

    by Others

    2.35per tablet
  • Oflomac Forte Oral Solution 30 ml

    by Others

    2.13per tablet
  • Zanocin 100 Liquid 60 ml

    by Others

    2.12per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

If you miss a dose of Zanocin 100 Solution, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

No, Zanocin 100 Solution should not be taken along with dairy products as it might affect the absorption and efficacy of Zanocin 100 Solution. However, you can take it with a meal that includes these foods or drinks.

Zanocin 100 Solution makes your skin sensitive to sunlight known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In case of emergency, you should always wear sunscreen before going out.

Yes, after taking Zanocin 100 Solution, you may have diarrhea. Zanocin 100 Solution is an antibiotic that kills or prevents bacterial growth, so in case some good intestinal bacteria which aid in digestion might also get killed. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration).

No, Zanocin 100 Solution should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor

You are recommended to take Zanocin 100 Solution either 2 hours before or 2 hours after taking an antacid, multivitamin, or other product that has calcium/magnesium/aluminium/iron/zinc, antiulcer agent (sucralfate) or anti-HIV drug (didanosine).

Drug-Drug Interactions Checker List

  • ASPIRIN
  • WARFARIN
  • CLOZAPINE
  • OLANZAPINE
  • CHLORPROPAMIDE
  • GLIMEPIRIDE
  • GLIPIZIDE
  • GLYBURIDE
  • METFORMIN
  • TOLAZAMIDE
  • TOLBUTAMIDE
  • AMIODARONE
  • DISOPYRAMIDE
  • PROCAINAMIDE
  • QUINIDINE
  • IBUPROFEN
  • NAPROXEN
  • SUCRALFATE
  • DIDANOSINE

Special Advise

Tendon damage (especially to the Achilles tendon) can occur within 48 hours of starting Zanocin 100 Solution treatment. The onset of symptoms and signs of the side effects may be delayed several months after stopping treatment. At the first sign of tendinitis (like painful swelling, inflammation), immediately stop taking Zanocin 100 Solution. The affected limbs should be appropriately treated (e.g., immobilisation). Corticosteroids medicines (like anti-inflammatory drugs including cortisone, prednisone, prednisolone, methylprednisolone, dexamethasone, betamethasone, hydrocortisone should not be used if signs of tendon rupture occur.

Disease/Condition Glossary

A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our bodies. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly of spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. People with weak immune systems or taking immunosuppressive medicine can make them more prone to bacterial infection.

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