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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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About Zelocip-CF Cream

Zelocip-CF Cream belongs to a class of dermatological medication ‘Topical Anti-Infectives with steroids’ used to treat the skin's fungal and bacterial infections. Besides this, Zelocip-CF Cream also reduces swelling, itching, and redness caused due to certain skin problems. Fungal infection is a skin disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another). A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly.

Zelocip-CF Cream is a combination of three drugs, namely: Ciprofloxacin (antibiotic), Clotrimazole (antifungal), and Fluocinolone acetonide (corticosteroid). Ciprofloxacin belongs to the class of antibiotics that works by interfering with a bacterial enzyme involved in repairing and replicating the DNA (genetic material) of bacteria. Thereby, it kills bacteria and prevents the spread of the infection. The fungal cell membranes are essential for their survival as they prevent unwanted substances into the cells and stop the leakage of cell contents. Clotrimazole belongs to the class of antifungals that works by damaging the fungal cell membranes and kills fungi. Fluocinolone acetonide is a corticosteroid that works by acting inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any allergens, such chemicals are released normally.

Use Zelocip-CF Cream as prescribed by your doctor. Zelocip-CF Cream is only for external use. You are advised to use Zelocip-CF Cream for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience swelling, itching, redness, irritation, or burning sensation at the site of application. Most of these side effects of Zelocip-CF Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Zelocip-CF Cream or any other medicines, please tell your doctor. Zelocip-CF Cream should be used with caution in children as it may affect growth in children and teens. If you are pregnant or breastfeeding, please consult a doctor before using Zelocip-CF Cream. Avoid using Zelocip-CF Cream on scrapes, cuts, open wounds, or damaged or broken skin. Do not wrap or cover the treated area with airtight dressings unless advised by a doctor. Do not swallow Zelocip-CF Cream. In case of accidental swallowing, contact a doctor immediately. You are advised not to scratch or prick the infected areas of your skin as it may spread the infection.  

Uses of Zelocip-CF Cream

Bacterial skin infections, Fungal skin infections

Directions for Use

Zelocip-CF Cream is only for external use. Take a small amount of Zelocip-CF Cream on the fingertip and apply as a thin layer on the clean and dry affected area as prescribed by your doctor. Avoid contact of Zelocip-CF Cream with nose, mouth, or eyes. In case Zelocip-CF Cream comes in contact with these areas accidentally, rinse with water thoroughly. Wash your hands before and after using Zelocip-CF Cream if hands are not the affected area to prevent the spread of infection.

Medicinal Benefits

Zelocip-CF Cream is a combination of three drugs, namely Ciprofloxacin, Clotrimazole, and Fluocinolone acetonide. Ciprofloxacin is a broad-spectrum antibiotic that acts against both aerobic (grow in the presence of oxygen) and anaerobic (increase in the absence of oxygen) gram-negative and gram-positive bacteria. It interferes with a bacterial enzyme involved in repairing and replicating bacteria's DNA (genetic material). Thus, it kills bacteria and clears the infection. Clotrimazole is an antifungal that damages the fungal cell membranes, which are essential for their survival. They prevent unwanted substances from entering into the cells and stop the leakage of cell contents and kill fungi. Fluocinolone acetonide is a corticosteroid that acts inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. When the skin reacts to any allergens, such chemicals are usually released. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zelocip-CF Cream

  • Swelling
  • Itching
  • Redness
  • Irritation
  • Burning sensation at the site of application

Drug Warnings

If you are allergic to Zelocip-CF Cream or any other medicines, please tell your doctor. If you have diabetes, adrenal gland or liver problems, skin reaction to any steroid medicine, or any skin infection, inform your doctor before taking Zelocip-CF Cream. Do not use Zelocip-CF Cream in more than prescribed doses, or for a prolonged time as it may cause adverse effects. Zelocip-CF Cream should be used with caution in children as it may affect growth in children and teens. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Zelocip-CF Cream. Avoid using Zelocip-CF Cream on scrapes, cuts, open wounds, damaged or broken skin. You recommend avoiding sunlight or tanning beds as ciprofloxacin in Zelocip-CF Cream may increase the risk of sunburn. Do not wrap or cover the treated area with airtight dressings unless advised by a doctor. Do not swallow Zelocip-CF Cream. In case of accidental swallowing, consult a doctor immediately. You are advised not to scratch or prick the infected skin areas as it may spread the infection. 

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk barefoot. Wear flip-flops or sandals to prevent fungal infections.
  • Do not scratch the affected area of the skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes, or socks with others to prevent the spread of infection.
  • Wash your bed sheets and towels regularly.
  • Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.
  • Consuming food rich in probiotics helps in developing the immune system against allergies.
  • Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.
  • Avoid consumption of foods with excess sugar as it may flare up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats, and fish in your diet.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Habit Forming

No

Therapeutic Class

ANTIBACTERIAL AND CORTICOSTEROID

Author Details

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FAQs

Zelocip-CF Cream contains Ciprofloxacin, Clotrimazole, and Fluocinolone acetonide. Ciprofloxacin belongs to the class of antibiotics that works by interfering with a bacterial enzyme involved in repairing and replicating the DNA (genetic material) of bacteria. Thus, kills bacteria and clears the infection. Clotrimazole is an antifungal that works by damaging the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Thereby, it kills fungi. Fluocinolone acetonide is a corticosteroid that acts inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching, and swelling. Thereby, reduces swelling, itching, and redness caused by certain infections.

Zelocip-CF Cream may cause skin itching at the site of application as a temporary side effect. However, if the itching persists or worsens, please consult a doctor.

You are recommended to cover the treated area of skin with bandages or dressings only if advised by your doctor else it may increase the risk of side effects.

You are recommended to use Zelocip-CF Cream for as long as your doctor has prescribed it. However, if the condition persists or worsens after 2 to 4 weeks of treatment with Zelocip-CF Cream, please consult a doctor.

Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

Zelocip-CF Cream contains clotrimazole that may affect the latex in contraceptives such as diaphragms and condoms and reduce their effectiveness. Therefore, it is recommended to use other contraceptive methods for minimum 5 days after using Zelocip-CF Cream in the genital area. However, please consult a doctor if you any queries regarding this.

Zelocip-CF Cream contains ciprofloxacin that may increase the risk of sunburn. Therefore, it is advised to avoid sunlight or tanning beds, wear protective clothing and use a sunscreen while going out in the sun to prevent sunburn while using Zelocip-CF Cream. However, please consult a doctor if you experience severe redness, itching, swelling or rash after being exposed to the sun.

Drug-Drug Interactions Checker List

  • BUDESONIDE+FORMOTEROL
  • DULOXETINE
  • ACETAMINOPHEN+HYDROCODONE

Special Advise

  • Please consult a dermatologist if your skin infection persists or worsens after using Zelocip-CF Cream for 2-4 weeks.
  • Zelocip-CF Cream contains Fluocinolone Acetonide a corticosteroid hence, should not be applied on broken or infected skin including acne rosacea, cold sores, chickenpox, ringworm, thrush, or athlete's foot. 

Disease/Condition Glossary

Fungal infection: It is a skin disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another). Fungal infection symptoms include scaly skin, blisters, itching, swelling, irritation, and redness. Antifungal medicines are usually used to treat fungal infections.

Bacterial infection: It is a condition in which harmful bacteria grow in the body and cause infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes, namely spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever, and tiredness.  

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