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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

ACECLOFENAC-100MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zerodol 100 Tablet

Zerodol 100 Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) or pain killers used to reduce and relieve pain, and inflammation (swelling) associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Arthritis is a condition which affects the joints. Symptoms include swelling, pain, inflammation, stiffness, and tenderness. 

Zerodol 100 Tablet contains 'Aceclofenac' which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

You are advised to take Zerodol 100 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Zerodol 100 Tablet may cause certain common side-effects such as dizziness, diarrhoea, nausea, and increased liver enzymes in the blood. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Zerodol 100 Tablet may cause drowsiness and dizziness, so drive with caution. Zerodol 100 Tablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Zerodol 100 Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Zerodol 100 Tablet

Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis

Directions for Use

Take Zerodol 100 Tablet with or after food. Swallow Zerodol 100 Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Zerodol 100 Tablet belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) used to reduce and relieve pain, redness, and inflammation (swelling) in patients suffering from osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Zerodol 100 Tablet works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zerodol 100 Tablet
  • Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
  • Keep a food diary to track potential food allergens.
  • Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
  • Wear loose, comfortable clothing made from soft fabrics like cotton.
  • Apply cool compresses or take cool baths to reduce itching.
  • Use gentle soaps and avoid harsh skin products.
  • Reduce stress through relaxation techniques like meditation or deep breathing.
  • Try eating smaller meals (4-5 times) instead of large ones to make it easier on your stomach.
  • Avoid foods that are spicy, fatty, or high in insoluble fibre.
  • Consuming soluble fibre (such as psyllium) can help with constipation, and probiotics may reduce bloating and discomfort.
  • Stay away from carbonated drinks, alcohol, caffeine, and smoking, as they can upset your stomach.
  • Reducing stress, losing weight, and exercising regularly for 20-30 minutes can help improve digestion and reduce stomach issues.
  • Poor sleep can worsen stomach problems, so focus on good sleep habits or use tools like Sleepio to improve your sleep.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

If you have had any recent heart surgery, do not take Zerodol 100 Tablet as it can increase the risk of heart attack or stroke. Do not take Zerodol 100 Tablet if you are allergic to aceclofenac or other NSAIDs (such as ibuprofen, diclofenac or naproxen); if you have stomach ulcers, have suffered bleeding problems, clotting problems, severe heart, liver or kidney problems. Inform your doctor if you have or had disorders of the stomach, blood circulation problems to the brain, asthma, porphyria (blood disorder), diabetes, high blood pressure, auto-immune diseases, connective tissue diseases; if you are recovering from major surgery or if you are elderly. Consult your doctor if you are pregnant or breastfeeding. Zerodol 100 Tablet may cause drowsiness and dizziness, so drive only if you are alert. Zerodol 100 Tablet is not recommended for children as safety has not been established. Avoid consuming alcohol along with Zerodol 100 Tablet as it could lead to increased drowsiness and may also increase the risk of stomach bleeding. Stop taking Zerodol 100 Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach such as blood in stools. Do not take any other NSAIDs for pain relief along with Zerodol 100 Tablet unless prescribed. 

Drug-Drug Interactions

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AceclofenacAtenolol
Severe

Drug-Drug Interactions

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AceclofenacAtenolol
Severe
How does the drug interact with Zerodol 100 Tablet:
Co-administration of Atenolol with Zerodol 100 Tablet could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Zerodol 100 Tablet, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

Zerodol 100 Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Zerodol 100 Tablet works by blocking the effect of chemical messengers that causes pain and swelling. This helps in reducing mild to moderate pain and inflammation at the injured or damaged site.

Do not take Zerodol 100 Tablet for longer durations as it might increase the risk of heart problems and stomach bleeding. Do not exceed the dose and duration of treatment prescribed by the doctor.

To treat your condition effectually continue taking Zerodol 100 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Zerodol 100 Tablet .

Taking Zerodol 100 Tablet with pain killers like aspirin and ibuprofen can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor if you have gastrointestinal bleeding or other bleeding problems like haemophilia before using Zerodol 100 Tablet .

Diarrhoea might be a side-effect of Zerodol 100 Tablet . Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • NAPROXEN
  • CELECOXIB
  • ETORICOXIB
  • CITALOPRAM
  • ESCITALOPRAM
  • FLUOXETINE
  • FLUVOXAMINE
  • PAROXETINE
  • SERTRALINE
  • LITHIUM
  • DIGOXIN
  • ENALAPRIL
  • LISINOPRIL
  • LOSARTAN
  • HYDRALAZINE
  • METHYLDOPA
  • CLONIDINE
  • PROPRANOLOL
  • MOXONIDINE
  • CIPROFLOXACIN
  • OFLOXACIN
  • LEVOFLOXACIN
  • MOXIFLOXACIN
  • FUROSEMIDE
  • WARFARIN
  • HEPARIN
  • CLOPIDOGREL
  • METHOTREXATE
  • MIFEPRESTONE
  • HYDROCORTISONE
  • PREDNISOLONE
  • CYCLOSPORINE
  • TACROLIMUS
  • ZIDOVUDINE
  • GLIBENCLAMIDE
  • GLICLAZIDE
  • CANDESARTAN
  • AMILORIDE HYDROCHORIDE
  • TOLBUTAMIDE

Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include a past injury such as torn cartilage, dislocated joints and ligament injuries. 

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain usually starts in the lower back and can spread to the neck, damaged joints or other parts of the body. Symptoms of ankylosing spondylitis include decreased flexibility which usually leads to hunched-forward posture, pain and back and joints.

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