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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS

About Zerodol-MR Tablet 10's

Zerodol-MR Tablet 10's is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, and headache. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.
 
Zerodol-MR Tablet 10's contains Tizanidine (muscle relaxant) and Aceclofenac (NSAID). Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac works by blocking the effect of prostaglandins which cause pain and inflammation. Thereby, reduces mild to moderate pain and inflammation. Together, Zerodol-MR Tablet 10's helps in relieving pain due to muscle spasms.
 
You are advised to take Zerodol-MR Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side-effects such as nausea, vomiting, stomach pain, loss of appetite, heartburn, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Zerodol-MR Tablet 10's may cause drowsiness and dizziness, so drive with caution. Zerodol-MR Tablet 10's is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with Zerodol-MR Tablet 10's as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any interactions.

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Zerodol-MR Tablet 10's

Pain and inflammation associated with musculoskeletal and joint disorders.

Medicinal Benefits

Zerodol-MR Tablet 10's is a combination of two drugs, namely: Tizanidine and Aceclofenac. Zerodol-MR Tablet 10's is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, and headache. Tizanidine is a muscle relaxant that works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac is an analgesic that works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Zerodol-MR Tablet 10's helps in relieving pain due to muscle spasms.

Side Effects of Zerodol-MR Tablet 10's

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Loss of appetite
  • Heartburn

Directions for Use

Swallow Zerodol-MR Tablet 10's as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Zerodol-MR Tablet 10's if you are allergic to any of its components. Inform your doctor if you have/ had high blood pressure, heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, bypass surgery, heart attack, blood circulation problems, or inflammation of the intestine, high cholesterol, diabetes, asthma, inflammatory bowel disease, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Zerodol-MR Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Zerodol-MR Tablet 10's is not recommended for children as safety and effectiveness have not been established. Stop taking Zerodol-MR Tablet 10's and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.

Therapeutic Class

ANALGESICS

Drug-Drug Interactions

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TizanidineDronedarone
Critical
TizanidineFluvoxamine
Critical

Drug-Drug Interactions

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TizanidineDronedarone
Critical
How does the drug interact with Zerodol-MR Tablet 10's:
Coadministration of Zerodol-MR Tablet 10's with Dronedarone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zerodol-MR Tablet 10's with Dronedarone is generally avoided as it can result in an interaction, it can be taken when prescribed by a doctor. If you experience sudden dizziness, shortness of breath, palpitations, or chest pain, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TizanidineFluvoxamine
Critical
How does the drug interact with Zerodol-MR Tablet 10's:
Taking Fluvoxamine with Zerodol-MR Tablet 10's it can increases the risk of side effects.

How to manage the interaction:
Although Fluvoxamine with Zerodol-MR Tablet 10's is not recommended, but can be taken together if prescribed by a doctor. However, if you experience drowsiness, dizziness, low blood pressure, slurred speech, confusion, or severe weakness, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
TizanidineCisapride
Critical
How does the drug interact with Zerodol-MR Tablet 10's:
Coadministration of Zerodol-MR Tablet 10's with Cisapride can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Zerodol-MR Tablet 10's with Cisapride is avoided as it can result in an interaction, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience sudden dizziness, shortness of breath, palpitations, or vomiting. Do not discontinue any medications without consulting your doctor.
TizanidineCiprofloxacin
Critical
How does the drug interact with Zerodol-MR Tablet 10's:
Coadministration of Ciprofloxacin and Zerodol-MR Tablet 10's together can increase the risk of side effects.

How to manage the interaction:
Using Ciprofloxacin and Zerodol-MR Tablet 10's together is avoided, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, weakness, sweating, or palpitations contact the doctor immediately. Do not discontinue any medications without consulting the doctor.
TizanidineZiprasidone
Critical
How does the drug interact with Zerodol-MR Tablet 10's:
Co-administration of Zerodol-MR Tablet 10's with Ziprasidone can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Zerodol-MR Tablet 10's with Ziprasidone is not recommended, as it can result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
TizanidineSaquinavir
Critical
How does the drug interact with Zerodol-MR Tablet 10's:
Combining Zerodol-MR Tablet 10's with Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Zerodol-MR Tablet 10's with Saquinavir is not recommended, as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhoea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
AceclofenacAtenolol
Severe
How does the drug interact with Zerodol-MR Tablet 10's:
Co-administration of Atenolol with Zerodol-MR Tablet 10's could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Zerodol-MR Tablet 10's, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
TizanidineMoexipril
Severe
How does the drug interact with Zerodol-MR Tablet 10's:
Combining Zerodol-MR Tablet 10's and Moexipril can lower your blood pressure.

How to manage the interaction:
Taking Zerodol-MR Tablet 10's and Moexipril together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, contact your doctor immediately. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position, and do not discontinue any medications without consulting your doctor.
TizanidineNorfloxacin
Severe
How does the drug interact with Zerodol-MR Tablet 10's:
Coadministration of Norfloxacin Zerodol-MR Tablet 10's may significantly increase the blood levels and effects of Zerodol-MR Tablet 10's.

How to manage the interaction:
Although there is a possible interaction, Norfloxacin with Zerodol-MR Tablet 10's can be taken if prescribed by the doctor. Consult the prescriber if you experience symptoms such as dizziness, drowsiness, lightheadedness, headache, shortness of breath, palpitations, clumsiness or unsteadiness, or vision problems. Do not discontinue any medications without consulting a doctor.
TizanidineNitroprusside
Severe
How does the drug interact with Zerodol-MR Tablet 10's:
Co-administration of Nitroprusside with Zerodol-MR Tablet 10's can increase the risk of low blood pressure.

How to manage the interaction:
Co-administration of Zerodol-MR Tablet 10's and Nitroprusside can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like headache, dizziness, or irregular heart rate, contact your doctor immediately. Avoid driving or operating hazardous machinery while taking these medications. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • HYDROCODONE
  • CITALOPRAM
  • ESCITALOPRAM
  • DULOXETINE
  • FLUOXETINE
  • FLUVOXAMINE
  • PAROXETINE
  • SERTRALINE
  • LITHIUM
  • ZOLPIDEM
  • PREGABALIN
  • DIPHENHYDRAMINE

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Author Details

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Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific body area). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.

Arthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

Zerodol-MR Tablet 10's Substitute

Substitutes safety advice
  • Nixar MR Tablet 10's

    by Others

    9.81per tablet
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