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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About ZIDOVIR 300MG CAPSULE

ZIDOVIR 300MG CAPSULE is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS). Symptoms of HIV include fever, chills, night sweats, muscle aches, etc. This medicine is also used for the prevention of maternal-fetal HIV transmission.

ZIDOVIR 300MG CAPSULE contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.

ZIDOVIR 300MG CAPSULE may cause certain side effects such as nausea, headache, stomach pain, loss of appetite, vomiting, nausea, cough, diarrhea, nasal congestion, fever, tiredness, muscle pain, dizziness, and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. ZIDOVIR 300MG CAPSULE should be taken as advised by your doctor. Your doctor will decide the dose of the medicine based on your health condition. Do not take more than the recommended dose.

ZIDOVIR 300MG CAPSULE should be avoided if you are allergic to it. Before taking this medicine, inform your doctor if you have heart problems, liver/kidney diseases, haematological toxicity, severe anemia, hepatomegaly with steatosis, lactic acidosis, or peripheral nephropathy. If you are pregnant and breastfeeding, let your doctor know before taking ZIDOVIR 300MG CAPSULE. ZIDOVIR 300MG CAPSULE can be used in children only if recommended by the doctor. If prescribed, the child should be carefully monitored for any changes. ZIDOVIR 300MG CAPSULE is used to treat the infection but does not cure or prevent it. Inform your doctor about your medical history and the medicines you take to prevent possible interactions.

rxMedicinePrescription drug

Whats That

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Non returnable*
COD available

Online payment accepted

Composition

ZIDOVUDINE-300MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of ZIDOVIR 300MG CAPSULE

HIV Infection.

Medicinal Benefits

ZIDOVIR 300MG CAPSULE contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection. ZIDOVIR 300MG CAPSULE is used in combination with other antiretroviral medicines to help reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

Side Effects of ZIDOVIR 300MG CAPSULE

  • Nausea
  • Abdominal pain
  • Vomiting
  • Dizziness
  • Back pain
  • Loss of appetite
  • Tiredness
  • Nasal congestion
  • Fever
  • Cough

Directions for Use

Tablet/Capsule: Take this medicine as advised by your doctor. It should be taken without food at least 2 hours before the meal. Swallow as a whole with a glass of water. Do not chew, crush or break the medicine.Suspension: Take ZIDOVIR 300MG CAPSULE as prescribed by your doctor. Shake the container well before each use. Measure and consume the required amount of ZIDOVIR 300MG CAPSULE using a measuring cup. It is advised not to consume more than the recommended dose of medicine.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

ZIDOVIR 300MG CAPSULE should be avoided if you are allergic to it. It is advised not to take this medicine along with ganciclovir, interferon alpha, ritonavir, stavudine, daunorubicin, bleomycin, idarubicin, and epirubicin, as it can cause serious side effects. Hence, avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, hematological toxicity, anemia, hepatomegaly with steatosis, lactic Acidosis, and peripheral nephropathy, on priority. It is not known whether ZIDOVIR 300MG CAPSULE can be given to pregnant and breastfeeding women. Hence, inform your doctor if you are pregnant and breastfeeding before receiving ZIDOVIR 300MG CAPSULE. ZIDOVIR 300MG CAPSULE can be used in children only if recommended by the pediatrician. If prescribed, the child should be carefully monitored for any changes. ZIDOVIR 300MG CAPSULE is used to treat the infection but does not cure or prevent it. ZIDOVIR 300MG CAPSULE is used to treat the infection but does not cure or prevent it. This medicine is used in combination for the treatment of HIV infection. This medicine may cause dizziness; hence, avoid driving or operating machines while taking ZIDOVIR 300MG CAPSULE.

Therapeutic Class

ANTIRETROVIRAL AGENTS

Drug-Drug Interactions

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ZidovudineCladribine
Severe
ZidovudineGanciclovir
Severe

Drug-Drug Interactions

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ZidovudineCladribine
Severe
How does the drug interact with ZIDOVIR 300MG CAPSULE:
Combining Cladribine with ZIDOVIR 300MG CAPSULE can increase the risk of developing serious infections.

How to manage the interaction:
Taking Cladribine with ZIDOVIR 300MG CAPSULE together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
ZidovudineGanciclovir
Severe
How does the drug interact with ZIDOVIR 300MG CAPSULE:
Using ZIDOVIR 300MG CAPSULE together with ganciclovir may increase the risk of side effects affecting the blood leading to decreased levels of blood cells.

How to manage the interaction:
Taking ganciclovir with ZIDOVIR 300MG CAPSULE together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, sore throat, rashes, tiredness, headaches, irritation, confusion, edema, fatigue, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ZidovudineBaricitinib
Severe
How does the drug interact with ZIDOVIR 300MG CAPSULE:
coadministration of baricitinib and ZIDOVIR 300MG CAPSULE can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with ZIDOVIR 300MG CAPSULE if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
ZidovudineInfliximab
Severe
How does the drug interact with ZIDOVIR 300MG CAPSULE:
When ZIDOVIR 300MG CAPSULE and Infliximab are taken together, the body breaks down ZIDOVIR 300MG CAPSULE faster. This can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab with ZIDOVIR 300MG CAPSULE together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ZidovudineValganciclovir
Severe
How does the drug interact with ZIDOVIR 300MG CAPSULE:
Combining Valganciclovir with ZIDOVIR 300MG CAPSULE can increase the risk of side effects.

How to manage the interaction:
Although taking Valganciclovir and ZIDOVIR 300MG CAPSULE together can cause an interaction, it can be taken if your doctor has suggested it. If you experience any complications or symptoms, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ZidovudineClozapine
Severe
How does the drug interact with ZIDOVIR 300MG CAPSULE:
Combining ZIDOVIR 300MG CAPSULE with Clozapine can increase the risk of neutropenia.

How to manage the interaction:
There may be a possibility of interaction between Clozapine and ZIDOVIR 300MG CAPSULE, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - such as a severe infection, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, or pain while urinating - it is important to contact your doctor right away." Do not stop using any medications without a doctor's advice.
ZidovudineEtanercept
Severe
How does the drug interact with ZIDOVIR 300MG CAPSULE:
When Etanercept is used with ZIDOVIR 300MG CAPSULE, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking Etanercept with ZIDOVIR 300MG CAPSULE together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
ZidovudineTofacitinib
Severe
How does the drug interact with ZIDOVIR 300MG CAPSULE:
Taking ZIDOVIR 300MG CAPSULE with Tofacitinib may increase the risk of serious infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and ZIDOVIR 300MG CAPSULE, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TACROLIMUS
  • RITONAVIR
  • STAVUDINE
  • EPIRUBICIN
  • DOXORUBICIN
  • GANCICLOVIR
  • INTERFERON ALFA

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration.  

Habit Forming

No

Special Advise

  • Get an HIV test done at least every three months.
  • Regular kidney and liver function and bone mineral density tests while taking ZIDOVIR 300MG CAPSULE are advised. 
  • Regularly get blood and urine tests done while taking ZIDOVIR 300MG CAPSULE.
  • ZIDOVIR 300MG CAPSULE may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking ZIDOVIR 300MG CAPSULE should be carefully monitored throughout the treatment.

Disease/Condition Glossary

HIV Infection: Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Virus (AIDS). Symptoms of HIV include headache, fever, chills, joint pain, fatigue, swollen lymph nodes, sore throat, mouth nodes, muscle aches, etc. ZIDOVIR 300MG CAPSULE helps reduce the symptoms, control the infection, and also helps improve the HIV patient’s quality of life.

ZIDOVIR 300MG CAPSULE Substitute

Substitutes safety advice
  • Zidine 300 mg Tablet 10's

    by Others

    624.35per tablet
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