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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition

CEFIXIME-50MG

Manufacturer/Marketer

FDC Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Zifi DT 50 mg Tablet

Zifi DT 50 mg Tablet belongs to a group of cephalosporin antibiotics. It is used to treat susceptible organisms (bacteria)-caused infections of the ear, nose, sinuses (sinusitis), throat (tonsillitis, pharyngitis), chest and lungs (bronchitis, pneumonia) and urinary system (cystitis and kidney infections). Additionally, it is also prescribed to treat uncomplicated gonorrhoea (cervical/urethral).

Zifi DT 50 mg Tablet contains Cefixime which works by inhibiting cell wall synthesis. In turn, Zifi DT 50 mg Tablet weakens and destroys the bacterial cell wall, leading to death. As a result, Zifi DT 50 mg Tablet helps to treat bacterial infections.

Zifi DT 50 mg Tablet should be used under the supervision of a doctor or healthcare professional. Use it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Like all medicines, Zifi DT 50 mg Tablet may cause some common side effects, including diarrhoea, nausea, loose stools, abdominal pain, dyspepsia, indigestion, and vomiting. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects are persistent or you notice any unusual symptoms developing in the child, inform your doctor immediately.

Inform your doctor about your child's entire medical history. Other drugs or supplements should not be combined with Zifi DT 50 mg Tablet unless prescribed by a doctor. Even if your child is feeling better, do not miss any dose and complete the entire course of medication. Stopping the medication too soon may cause the infection to recur or worsen.

Uses of Zifi DT 50 mg Tablet

Bacterial Infections

Directions for Use

Give this medicine to your child as directed by your physician or as per instructions in the package leaflet. Disperse the tablet in the prescribed amount of water and give the contents to your child. It should not be crushed or swallowed whole.

Medicinal Benefits

Zifi DT 50 mg Tablet is a short-term medication for a wide range of bacterial infections. It prevents the growth of bacteria by stopping the formation of a protective covering which is vital for its growth. It prevents and treats bacterial infections like ear, nose, sinuses (sinusitis), throat (tonsillitis, pharyngitis), chest and lungs (bronchitis, pneumonia) and urinary system (cystitis and kidney infections).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zifi DT 50 mg Tablet

  • Diarrhoea

  • Nausea
  • Loose stools
  • Abdominal pain
  • Dyspepsia or indigestion
  • Vomiting

Drug Warnings

The presence of other medical problems or using other medications may affect the use of this medicine. So, before using Zifi DT 50 mg Tablet , let your doctor know about all your children's medical conditions, sensitivities, and all the ongoing medications.

Drug-Drug Interactions

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CefiximeCholera, live attenuated
Severe

Drug-Drug Interactions

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CefiximeCholera, live attenuated
Severe
How does the drug interact with Zifi DT 50 mg Tablet:
Co-administration of Zifi DT 50 mg Tablet with Cholera vaccine may reduce the effectiveness of the vaccine.

How to manage the interaction:
Talk to your doctor before receiving the cholera vaccine if you are currently being treated with Zifi DT 50 mg Tablet or have been treated within the last 14 days. To ensure adequate vaccine response, you should not receive cholera vaccine until at least 14 days after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to give probiotics after taking the full course of Zifi DT 50 mg Tablet to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.

  • The BRAT diet (bananas, rice, applesauce, toast) can help with diarrhoea from antibiotics.

  • Give plenty of water to the child. Staying hydrated is important, especially when you’re child sick.

  • Eating a broad range of plant-based foods such as vegetables, fruits, nuts, seeds, pulses, and whole grains helps to build a healthy gut microbiome.

  • Avoid feeding too many calcium-enriched foods and drinks because they may interfere with the functioning of Zifi DT 50 mg Tablet .

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Zifi DT 50 mg Tablet Substitute

Substitutes safety advice
  • Taxim O Dry Syrup Delicious Pineapple 30 ml

    by Others

    1.64per tablet
  • Zifi 50 Dry Syrup 30 ml

    by Others

    1.64per tablet
  • Taxim-O 50 mg Orange & Lemon Flavour Dry Syrup 60 ml

    by AYUR

    1.59per tablet
  • Zifi Readymix 50 mg Suspension 60 ml

    by AYUR

    1.64per tablet
  • Ziprax 50 Liquid 30 ml

    by Others

    1.64per tablet

Drug-Diseases Interactions

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CEFIXIME-50MGOther bacterial intestinal infections
Severe
CEFIXIME-50MGDisorders resulting from impaired renal tubular function
Moderate

Drug-Diseases Interactions

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CEFIXIME-50MGOther bacterial intestinal infections
Severe
How does the disease interact with Zifi DT 50 mg Tablet:
Almost all antibacterial medications have been associated to reports of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent offenders.

How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFIXIME-50MGDisorders resulting from impaired renal tubular function
Moderate
How does the disease interact with Zifi DT 50 mg Tablet:
The kidneys remove the majority of beta-lactam antibiotics as unaltered drugs and, in certain situations, as metabolites as well. In individuals with poor renal function, the blood concentrations of beta-lactam antibiotics and their metabolites may rise and their half-lives may be prolonged. According to the particular product package labelling, dosage modifications may be required. These alterations should be based on the severity of the infection as well as the degree of renal impairment. Renal function tests should be carried out on a regular basis during extended and/or high-dose therapy since these medicines have occasionally been linked to nephrotoxicity and changes in renal function.

How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised.
CEFIXIME-50MGAbnormal serum enzyme levels
Moderate
How does the disease interact with Zifi DT 50 mg Tablet:
Hepatitis cases have been associated to the usage of several cephalosporins. Alkaline phosphatase, AST, and ALT levels have all shown a brief spike. When these medications are provided to people with hepatic problems, caution and close observation are advised.

How to manage the interaction:
Caution and monitoring is recommended in patients with liver disorders.
CEFIXIME-50MGEpilepsy
Moderate
How does the disease interact with Zifi DT 50 mg Tablet:
It has been suggested that cephalosporins can cause seizures. In particular in patients with a history of epilepsy and/or where prescribed doses of cephalosporins were exceeded because of renal impairment, cephalosporins have been associated with nonconvulsive status epilepticus (NCSE), encephalopathy, coma, asterixis, neuromuscular excitability, and myoclonia. Depending on the creatinine clearance, change the dosage. In individuals with known seizure disorders, anticonvulsant medication should be maintained. Patients should get a neurological exam to see if medication should be stopped if CNS side effects like seizures happen.

How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Dose adjustment may be needed.

Drug-Drug Interactions Checker List

  • BCG VACCINE
  • CHOLERA VACCINE
  • TYPHOID VACCINE
  • WARFARIN
  • CARBAMAZEPINE

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. A few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E.coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.

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