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  3. Zigma CR 400 Tablet 10's

Zigma CR 400 Tablet 10's, Pack of 10 TABLETS
Zigma CR 400 Tablet 10's, Pack of 10 TABLETS
Zigma CR 400 Tablet 10's, Pack of 10 TABLETS
Zigma CR 400 Tablet 10's, Pack of 10 TABLETS
Zigma CR 400 Tablet 10's, Pack of 10 TABLETS
Zigma CR 400 Tablet 10's, Pack of 10 TABLETS
Zigma CR 400 Tablet 10's, Pack of 10 TABLETS
Zigma CR 400 Tablet 10's, Pack of 10 TABLETS
Zigma CR 400 Tablet 10's, Pack of 10 TABLETS
Zigma CR 400 Tablet 10's, Pack of 10 TABLETS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Whats That

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Composition :

CARBAMAZEPINE-400MG

Manufacturer/Marketer :

Crescent Formulations Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About ZIGMA CR 400MG TABLET

ZIGMA CR 400MG TABLET belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy (fits) and trigeminal neuralgia (pain in the face's nerves). Epilepsy is a neurological disorder in which there is a sudden rush of electric impulses (electric activity) in the brain. As a result, the brain's electrical rhythms become imbalanced, resulting in recurrent episodes of seizures or fits. Trigeminal neuralgia is a condition which affects the trigeminal nerve that carries sensations from the face to the brain. 

ZIGMA CR 400MG TABLET contains 'Carbamazepine' that reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Thus, ZIGMA CR 400MG TABLET decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. 

You are advised to take ZIGMA CR 400MG TABLET for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, tiredness, uncontrolled movements, nausea, headache, changes in liver enzymes or low white blood cells count, and minor skin reactions. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking ZIGMA CR 400MG TABLET for as long as your doctor has prescribed. Please do not stop taking ZIGMA CR 400MG TABLET without consulting your doctor to avoid worsening of seizures. Do not take ZIGMA CR 400MG TABLET if you are pregnant or planning for pregnancy unless prescribed by the doctor as it could lead to serious congenital disabilities. It is safe to take ZIGMA CR 400MG TABLET while breastfeeding; however, consult your doctor immediately if you think that the baby is having side-effects like excessive sleepiness, skin reactions or yellowing of skin or eyes. ZIGMA CR 400MG TABLET causes drowsiness and dizziness, so drive only if you are alert. ZIGMA CR 400MG TABLET should not be given to children unless prescribed. Avoid consuming alcohol along with ZIGMA CR 400MG TABLET as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of ZIGMA CR 400MG TABLET

Epilepsy/seizures, Trigeminal neuralgia

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Medicinal Benefits

ZIGMA CR 400MG TABLET belongs to a group of medicines called anti-convulsants or anti-epileptics used to treat epilepsy and trigeminal neuralgia (face nerve pain). ZIGMA CR 400MG TABLET works by reducing the electrical impulses and subsequent firing of the nerve impulses that cause fits. ZIGMA CR 400MG TABLET decreases the excessive and abnormal nerve activity in the brain, thereby helping in controlling seizures. ZIGMA CR 400MG TABLET is also used to relieve nerve pain associated with trigeminal neuralgia. People with glossopharyngeal neuralgia may also experience benefit with ZIGMA CR 400MG TABLET. ZIGMA CR 400MG TABLET is not associated with any psychological or physical dependence, and there is no potential for abuse.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zigma CR 400 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid intake of alcohol.
  • Take a balanced diet with plenty of fruits, vegetables, whole grains, and lean protein.
  • Practice healthy weight management by healthy lifestyle.
  • Practice regular exercise, as it helps maintain liver health.
  • Eosinophil levels can be lowered by eating fruits and vegetables, avoiding smoking, and consuming alcohol in moderation.
  • Several foods, such as ginger, garlic, pepper, turmeric, and honey, might boost immunity.
  • Avoid dairy products, including cheese, yoghurt, and milk.
  • Drink water and keep yourself hydrated.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.

Drug Warnings

Do not take ZIGMA CR 400MG TABLET if you are allergic to 'Carbamezapine' or any of its contents, have serious heart problems, blood illnesses, bone marrow problems, hypothyroidism, glaucoma, urinary retention, osteoporosis or taking anti-depressants called monoamine oxidase inhibitors (MAO's) within the last 14 days or taking herbal preparations containing St. John's wort as an antidepressant. Inform the doctor if you have low sodium levels in the blood or take medicines that could lower the blood's sodium levels, or using hormonal contraceptives. Do not stop taking ZIGMA CR 400MG TABLET without consulting your doctor to avoid worsening of seizures episodes. Do not take ZIGMA CR 400MG TABLET if you are pregnant unless prescribed by the doctor as ZIGMA CR 400MG TABLET might cause serious congenital disabilities. It is safe to take ZIGMA CR 400MG TABLET while breastfeeding; however, consult your doctor immediately if you think that the baby is having side-effects like excessive sleepiness, skin reactions or yellowing of skin or eyes. ZIGMA CR 400MG TABLET causes drowsiness and dizziness, so drive only if you are alert. ZIGMA CR 400MG TABLET should not be given to people less than 18 years of age until and unless prescribed by the doctor. Avoid consuming alcohol along with ZIGMA CR 400MG TABLET as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies or mood swings. 

Drug-Drug Interactions

verifiedApollotooltip
CarbamazepineIsavuconazole
Critical
CarbamazepineIsocarboxazid
Critical

Drug-Drug Interactions

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CarbamazepineIsavuconazole
Critical
How does the drug interact with Zigma CR 400 Tablet:
When Zigma CR 400 Tablet and Isavuconazole are taken together, Zigma CR 400 Tablet will reduce the effectiveness of the Isavuconazole.

How to manage the interaction:
Taking Isavuconazole with Zigma CR 400 Tablet is not recommended, it can be taken if prescribed by the doctor. Do not discontinue any medications without doctor's advice.
CarbamazepineIsocarboxazid
Critical
How does the drug interact with Zigma CR 400 Tablet:
Taking Zigma CR 400 Tablet with Isocarboxazid can cause serotonin syndrome(a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Using Zigma CR 400 Tablet with Isocarboxazid is not recommended, it can be taken if prescribed by your doctor. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
CarbamazepineRilpivirine
Critical
How does the drug interact with Zigma CR 400 Tablet:
When Rilpivirine is taken with Zigma CR 400 Tablet, it may decrease the blood levels of Rilpivirine, which may make Rilpivirine less effective in treating HIV infection.

How to manage the interaction:
Taking Rilpivirine with Zigma CR 400 Tablet is generally not advised, but it can be taken if prescribed by the doctor. Without consulting a doctor, never stop taking any drugs.
CarbamazepineNefazodone
Critical
How does the drug interact with Zigma CR 400 Tablet:
When Nefazodone is taken with Zigma CR 400 Tablet, it can effect both the medications. It increases the levels of Zigma CR 400 Tablet leading to side effects. At the same time, it may decrease the blood levels of Nefazodone, which may make Nefazodone less effective in treating your condition.

How to manage the interaction:
Taking Nefazodone with Zigma CR 400 Tablet is not recommended, but it can be taken if prescribed by the doctor. However, if you experience headache, nausea, vomiting, dizziness, confusion, slurred speech, visual disturbances, shaking, consult the doctor.
CarbamazepineMoclobemide
Critical
How does the drug interact with Zigma CR 400 Tablet:
Taking Zigma CR 400 Tablet with Moclobemide can increase the risk and severity of side effects.

How to manage the interaction:
Using Zigma CR 400 Tablet with Moclobemide is not recommended, it can be taken if recommended by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
CarbamazepineEfavirenz
Critical
How does the drug interact with Zigma CR 400 Tablet:
Using Zigma CR 400 Tablet together with efavirenz may reduce the effect of Zigma CR 400 Tablet.

How to manage the interaction:
Taking Efavirenz with Zigma CR 400 Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
CarbamazepineRegorafenib
Critical
How does the drug interact with Zigma CR 400 Tablet:
When Regorafenib is taken with Zigma CR 400 Tablet, it may decrease the blood levels of Regorafenib, which may make Regorafenib less effective in treating your condition.

How to manage the interaction:
Taking Regorafenib with Zigma CR 400 Tablet is generally not advised, but it can be taken if prescribed by the doctor. Without consulting a doctor, never stop taking any drugs.
CarbamazepineSelegiline
Critical
How does the drug interact with Zigma CR 400 Tablet:
Taking Zigma CR 400 Tablet with Selegiline can cause serotonin syndrome. (Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selegiline with Zigma CR 400 Tablet is not recommended, but it can be taken if prescribed by your doctor. However, if you experience symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
CarbamazepineTranylcypromine
Critical
How does the drug interact with Zigma CR 400 Tablet:
Using Zigma CR 400 Tablet with tranylcypromine can increase the risk of serotonin syndrome( a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Zigma CR 400 Tablet with Tranylcypromine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience hallucination(seeing and hearing things which do not exist), seizure(fits),increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
CarbamazepineNifedipine
Critical
How does the drug interact with Zigma CR 400 Tablet:
Coadministration of Nifedipine with Zigma CR 400 Tablet can reduce the blood levels of nifedipine, which may make the medication less effective.

How to manage the interaction:
Taking Nifedipine with Zigma CR 400 Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Aug 20, 2024 | 12:51 PM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

ZIGMA CR 400MG TABLET decreases the brain's excessive and abnormal nerve activity by blocking sodium currents in your brain and body. This reduces abnormal electrical activity between your nerve cells.

Do not discontinue ZIGMA CR 400MG TABLET without consulting your doctor. To treat your condition effectually continue taking ZIGMA CR 400MG TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking ZIGMA CR 400MG TABLET; your doctor will reduce the dose gradually to avoid worsening of seizures.

ZIGMA CR 400MG TABLET may affect the way hormone contraceptives work in your body. This may cause spotting or breakthrough bleeding. ZIGMA CR 400MG TABLET may increase the risk of pregnancy as it makes the contraceptive less effective. Talk to your doctor, he/she will discuss the most suitable type of contraception while taking ZIGMA CR 400MG TABLET to avoid pregnancy.

ZIGMA CR 400MG TABLET may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective contraception method during the treatment with ZIGMA CR 400MG TABLET and 2 weeks after the last dose. Avoid getting pregnant while taking ZIGMA CR 400MG TABLET as it could lead to serious congenital disabilities. Do not stop taking ZIGMA CR 400MG TABLET without consulting your doctor.

ZIGMA CR 400MG TABLET may cause hyponatremia (low sodium levels in the blood). This could lead to confusion, reduced concentration, vision problems, nausea, vomiting or worsening of seizures. Regular monitoring of sodium levels is advised while taking ZIGMA CR 400MG TABLET. Consult your doctor if you experience these symptoms.

Dry mouth could be a side-effect of ZIGMA CR 400MG TABLET. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Drug-Drug Interactions Checker List

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  • LITHIUM
  • MELATONIN
  • WARFARIN
  • DIPHENHYDRAMINE
  • CHOLECALCIFEROL

Special Advise

  • Regular monitoring of sodium levels while taking ZIGMA CR 400MG TABLET is advised to prevent hyponatremia.
  • Prolonged intake of ZIGMA CR 400MG TABLET can cause severe skin reactions called Stevens Johnsons syndrome (SJS) and toxic epidermal necrolysis (TEN). So in case you have any skin blister or rash immediately contact a doctor. 
  • ZIGMA CR 400MG TABLET may cause low blood cell count, so if you have any red or purple spots on the body, let your doctor know about this. 

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterised by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Trigeminal neuralgia: It is a condition affecting the trigeminal nerve in the face that causes painful sensations similar to electric shock on one side of the face. Symptoms include mild to severe facial pain often triggered by speaking, chewing, or brushing the teeth.

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