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Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Zintac 300 mg Tablet belongs to the class of gastrointestinal agents. It is used to treat indigestion, heartburn and acid reflux. Zintac 300 mg Tablet is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. Zintac 300 mg Tablet is also used to prevent and treat stomach ulcers. Often Zintac 300 mg Tablet is taken for a rare condition caused by a pancreatic or intestine tumour called Zollinger-Ellison Syndrome.

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Non returnable*
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Composition :

RANITIDINE-300MG

Manufacturer/Marketer :

Nicholas Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zintac 300 mg Tablet

Zintac 300 mg Tablet belongs to the class of gastrointestinal agents. It is used to treat indigestion, heartburn and acid reflux. Zintac 300 mg Tablet is also used for gastro-oesophageal reflux disease (GORD) when you get acid reflux. Zintac 300 mg Tablet is also used to prevent and treat stomach ulcers. Often Zintac 300 mg Tablet is taken for a rare condition caused by a pancreatic or intestine tumour called Zollinger-Ellison Syndrome.

Zintac 300 mg Tablet contains ranitidine, a histamine-2 (H2) receptor blocker that helps reduce stomach acid by blocking the actions of the H2 receptor. The H2 receptor lies in the parietal cells of the stomach wall and is responsible for the release of gastric acid secretion - extra gastric acid secretion damage the tissues in the food pipe, stomach, and duodenum.

Take this medication exactly as prescribed by your doctor. It would help if you kept taking medicine for long as your doctor recommends. If you stop early, your symptoms may come back, and your condition may worsen. Zintac 300 mg Tablet might have common side effects like headache, diarrhoea, constipation, and shortness of breath. These side effects are temporary and may get resolved after some time. However, if these side effects persist, contact your doctor.

It is recommended not to take Zintac 300 mg Tablet if you are allergic to any components present in Zintac 300 mg Tablet . If you are pregnant, planning to become pregnant, or are breastfeeding, you should not take this medication unless your doctor says it is necessary. Inform your doctor if you have stomach or intestinal cancer, liver problem, or will have an endoscopy in the future. And also, let your doctor know about your health condition and all the medicines you are taking before taking Zintac 300 mg Tablet to rule out any side effects.

Uses of Zintac 300 mg Tablet

Gastroesophageal Reflux Disease (GERD), Acid reflux, Heartburn, Peptic Ulcer

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Solution/Syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Zintac 300 mg Tablet helps in reducing the excess amount of stomach acid. In turn, it prevents the formation of an ulcer in the stomach (peptic ulcer), gastroesophageal reflux disease (GERD) with or without ulcer, and Zollinger Ellison Syndrome, in which the stomach makes an exceptionally high amount of acid.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zintac 300 mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

You should avoid taking Zintac 300 mg Tablet if you are allergic to Zintac 300 mg Tablet or H2 receptor blockers, have gastric cancer, or have liver disease. If you are a pregnant woman or nursing mother, do not consume Zintac 300 mg Tablet without first consulting your doctor. Zintac 300 mg Tablet may interact with a blood thinner (warfarin), antifungal (ketoconazole), or anti-HIV drug( atazanavir). Let your doctor know if you are taking these medicines. Intake of Zintac 300 mg Tablet may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in stool and mucous), immediately consult the doctor.

Drug-Drug Interactions

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RanitidineRilpivirine
Severe

Drug-Drug Interactions

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How does the drug interact with Zintac 300 mg Tablet:
Co-administration of Zintac 300 mg Tablet with Mesalazine can decrease the levels of Mesalazine, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Mesalazine with Zintac 300 mg Tablet, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
RanitidineRilpivirine
Severe
How does the drug interact with Zintac 300 mg Tablet:
Coadministration of Rilpivirine with Zintac 300 mg Tablet can reduce the acidity levels in the stomach and also decrease the effectiveness of Rilpivirine.

How to manage the interaction:
Although taking Zintac 300 mg Tablet together with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. To reduce the chance of interaction, take Zintac 300 mg Tablet at least 12 hours before or 4 hours after taking rilpivirine. Do not discontinue any medicine without consulting a doctor.
How does the drug interact with Zintac 300 mg Tablet:
Taking atazanavir with Zintac 300 mg Tablet can reduce the effectiveness of atazanavir.

How to manage the interaction:
Although taking Zintac 300 mg Tablet together with Atazanavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor if you experience unusual symptoms. Do not discontinue any medicine without consulting a doctor.
How does the drug interact with Zintac 300 mg Tablet:
Taking Zintac 300 mg Tablet and Dasatinib together reduces the effectiveness of Dasatinib.

How to manage the interaction:
Although taking Zintac 300 mg Tablet together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience any unusual symptoms. Do not discontinue any medicine without consulting a doctor.
How does the drug interact with Zintac 300 mg Tablet:
Coadministration of loperamide with Zintac 300 mg Tablet may significantly increase the blood levels of loperamide. This can increase the risk of serious side effect like irregular heart rhythm.

How to manage the interaction:
Although taking loperamide with Zintac 300 mg Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Zintac 300 mg Tablet:
Coadministration of Gefitinib with Zintac 300 mg Tablet can reduce the acidity levels in the stomach and also decrease the effectiveness of gefitinib

How to manage the interaction:
Taking Gefitinib with Zintac 300 mg Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. It is recommended that gefitinib is either taken 6 hours before or 6 hours after Zintac 300 mg Tablet to help minimize the impact of the interaction. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Zintac 300 mg Tablet:
Using Pazopanib with Zintac 300 mg Tablet can reduce the effectiveness of pazopanib

How to manage the interaction:
Although taking Zintac 300 mg Tablet together with Pazopanib can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Zintac 300 mg Tablet:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
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How does the drug interact with Zintac 300 mg Tablet:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
vv

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.

  • Before going to sleep, raise your bedhead, so your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.

  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing stomach acid backflow into the food pipe.

  • Include high fibre-containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal.

  • Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help prevent excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H Pyroli infections.

  • Avoid regular sitting continuously, as it can increase stomach acid production. Take a break of 5 minutes in 1 hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • WARFARIN
  • KETOCONAZOLE
  • ATAZANAVIR
  • ALUMINUM HYDROXIDE

Disease/Condition Glossary

The stomach is usually protected from acid by a mucous layer. In some cases, excess acid production erodes the mucous layer, which leads to complications like acidity. Due to this, acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing. Indigestion is the feeling of fullness. It occurs due to slow gastric emptying. Symptoms include stomach pain, bloating, heartburn, nausea and vomiting.

Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, the mucous layer gets irritated or eroded due to excess acid production, which leads to complications like GERD, hyperacidity, peptic ulcers, and heartburn. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing.

Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Zollinger-Ellison syndrome: It is characterized by the formation of tumours in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.

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