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  3. Zipris 40mg Capsule

Zipris 40mg Capsule, Pack of 1 Capsule
Written By Divya L , PharmaD
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

ZIPRASIDONE-40MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Zipris 40mg Capsule

Zipris 40mg Capsule belongs to a group of medicines called 'atypical antipsychotics,' primarily used to treat schizophrenia and manic depression (bipolar disorder). Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there (hallucinations), believe things that are not true, and feel unusually suspicious or confused. Manic depression or bipolar disorder is a serious brain disorder in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behavioural changes.

Zipris 40mg Capsule contains 'Ziprasidone’ that works by blocking the effects of chemical messengers (dopamine and serotonin) in the brain and improves thinking mood, and behaviour. Zipris 40mg Capsule helps in clear thinking and decreases hallucinations. Zipris 40mg Capsule is used for treating manic episodes of bipolar disorder and agitation in schizophrenia.

Take this as prescribed by your doctor. Your doctor will decide the dose and duration based on your medical condition and response to treatment. Common side effects of Zipris 40mg Capsule include drowsiness, dizziness, light-headedness, weakness, nausea, vomiting, runny nose, and cough. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Ziprasidone is not recommended for treatment in patients with Dementia-Related Psychosis. If you are using any prescription and non-prescription medications, let your doctor know before starting Zipris 40mg Capsule. Inform your doctor beforehand if you have a history of liver or kidney diseases, heart problems, breathing problems, diabetes, obesity, and fits. If you are pregnant, planning to conceive or a breastfeeding mother, inform your doctor before starting Zipris 40mg Capsule. Avoid consuming alcohol during the course as it can make you dizzy or drowsy. Do not drive or operate machinery while using Zipris 40mg Capsule since it can make you sleepy.

Uses of Zipris 40mg Capsule

Schizophrenia and Manic depression (bipolar disorder).

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Zipris 40mg Capsule is used to treat schizophrenia and manic depression (bipolar disorder). Zipris 40mg Capsule effectively treats manic episodes of bipolar disorder and agitation in schizophrenia. It contains 'Ziprasidone' that belongs to the class of atypical antipsychotics. Zipris 40mg Capsule works by restoring the balance of chemical messengers (dopamine and serotonin) in the brain. It is also known to improve thinking, mood and behaviour. Zipris 40mg Capsule helps in clear thinking and relieves the psychotic symptoms like delusions and hallucinations.

Storage

Keep out of sight and reach of children.
Side effects of Zipris 40mg Capsule
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Drug Warnings

Ziprasidone is not recommended for treatment in patients with Dementia-Related Psychosis. Brief your medical history if you have any liver or kidney diseases, heart problems (coronary artery disease, irregular heartbeat), breast cancer, breathing problems (sleep apnoea), stroke, diabetes, dementia, fits, low white blood cells, obesity, and swallowing problems before starting Zipris 40mg Capsule. Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother before using Zipris 40mg Capsule. Avoid consuming alcohol as it might lead to increased side effects like dizziness and drowsiness. Avoid driving or operating machinery as it may decrease your mental alertness, making you feel dizzy or drowsy. Zipris 40mg Capsule is not recommended for people below 18 years of age as the safety and effectiveness have not been established.

Drug-Drug Interactions

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ZiprasidoneAmiodarone
Critical
ZiprasidoneFluphenazine
Critical

Drug-Drug Interactions

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ZiprasidoneAmiodarone
Critical
How does the drug interact with Zipris 40mg Capsule:
Taking Amiodarone and Zipris 40mg Capsule may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Amiodarone with Zipris 40mg Capsule together should be avoided as it can likely result in an interaction, but it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ZiprasidoneFluphenazine
Critical
How does the drug interact with Zipris 40mg Capsule:
Taking Zipris 40mg Capsule with fluphenazine can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Zipris 40mg Capsule with Fluphenazine is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
ZiprasidoneMetoclopramide
Critical
How does the drug interact with Zipris 40mg Capsule:
Taking Metoclopramide with Zipris 40mg Capsule can increase the risk of side effects like uncontrolled movement disorder.

How to manage the interaction:
Taking Metoclopramide with Zipris 40mg Capsule is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience lip-smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping. Do not discontinue any medications without consulting a doctor.
ZiprasidonePromethazine
Critical
How does the drug interact with Zipris 40mg Capsule:
Co-administration of Promethazine with Zipris 40mg Capsule can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Promethazine with Zipris 40mg Capsule together can possibly result in an interaction, they can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
ZiprasidoneTrifluoperazine
Critical
How does the drug interact with Zipris 40mg Capsule:
Co-administration of Trifluoperazine with Zipris 40mg Capsule can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Trifluoperazine with Zipris 40mg Capsule together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
ZiprasidoneOxytocin
Critical
How does the drug interact with Zipris 40mg Capsule:
Taking Oxytocin with Zipris 40mg Capsule can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Oxytocin with Zipris 40mg Capsule is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
ZiprasidoneIloperidone
Critical
How does the drug interact with Zipris 40mg Capsule:
Taking Iloperidone with Zipris 40mg Capsule can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Zipris 40mg Capsule with Iloperidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
ZiprasidoneGrepafloxacin
Critical
How does the drug interact with Zipris 40mg Capsule:
Using Zipris 40mg Capsule together with grepafloxacin can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Zipris 40mg Capsule with Grepafloxacin is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
ZiprasidoneProcainamide
Critical
How does the drug interact with Zipris 40mg Capsule:
Co-administration of Procainamide with Zipris 40mg Capsule can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Procainamide with Zipris 40mg Capsule together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
ZiprasidoneChloroquine
Critical
How does the drug interact with Zipris 40mg Capsule:
Taking Chloroquine with Zipris 40mg Capsule can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Chloroquine with Zipris 40mg Capsule is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, confusion, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Exercise regularly as it helps in less cognitive decline and brain volume loss.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain anti-oxidants.
  • Eat nutritious food as it helps in cognitive stimulation.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Zipris 40mg Capsule Substitute

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Author Details

Doctor image

Written By

Divya L

PharmaD

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:35 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Zipris 40mg Capsule works by balancing the chemical messengers like dopamine and serotonin located in the brain, thereby improving mood, behaviour and thoughts.

Zipris 40mg Capsule should be used with caution in the medical history of liver or kidney diseases, heart problems (coronary artery disease, irregular heartbeat), breast cancer, breathing problems (sleep apnoea), stroke, diabetes, dementia, fits, low white blood cells, obesity, and swallowing problems. Please let your doctor know if you have any other medical problems before starting Zipris 40mg Capsule.

Zipris 40mg Capsule may make you sweat less and can likely cause heart stroke. Hence, it is advised to limit activities that cause overheat like an exercise in hot weather or using hot tubs. Drink plenty of fluids and dress lightly.

Zipris 40mg Capsule may cause dizziness. It is advised to avoid getting up too fast from a sitting or lying position to make you feel dizzy.

Zipris 40mg Capsule can cause a side effect called orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Zipris 40mg Capsule are advised to regularly monitor their blood pressure levels to avoid such unpleasant events.

Drug-Drug Interactions Checker List

  • CODEINE
  • HYDROCODONE
  • ALPRAZOLAM
  • LORAZEPAM
  • ZOLPIDEM
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • DIPHENHYDRAMINE
  • ESCITALOPRAM
  • FLUOXETINE
  • SERTRALINE
  • QUETIAPINE
  • TOPIRAMATE
  • LISDEXAMFETAMINE

Special Advise

  • Let your doctor know that you are taking Zipris 40mg Capsule if you are undergoing any medical tests.
  • Zipris 40mg Capsule may affect blood glucose levels; hence, it is advised to monitor blood sugar levels regularly. 
  • Ziprasidone may affect QT prolongation (heart muscle takes longer than usual to recharge between beats) that can cause serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram), and a family history of heart diseases.

Disease/Condition Glossary

Schizophrenia: It is a condition in which the person may see, hear or feel things that are not there, believe things that are not true, feel unusually suspicious or confused. Symptoms include hallucinations, delusions, thought disorders, movement disorders, disorganised thinking, loss of interest, lack of emotions, etc. Schizophrenia is triggered by physical, genetic, psychological, and environmental factors. Patients suffering from this disease may require lifelong treatment. Treatment involves a combination of medications, psychotherapy and care services.

Manic depression (bipolar disorder): It is a serious brain disorder in which a person goes through unusual mood changes (mood swings) and frequent change in his/her behaviour and thinking. 

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