Zobone 4mg Injection 1's
₹2059.4*
MRP ₹2511.5
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₹2134.5*
MRP ₹2511.5
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Zobone 4mg Injection 1's belongs to the class of medicines called 'bisphosphonates' used to treat osteoporosis (weak and brittle bones) caused by menopause or long-term steroid use. Zobone 4mg Injection 1's also treats Paget’s bone and high calcium levels caused by cancer. Osteoporosis is a bone disease that weakens and thins bones by decreasing bone density, common in post-menopausal women. As the density of bones decreases, they weaken and are more likely to break.
Zobone 4mg Injection 1's contains Zoledronic acid that works by binding to the bone tightly and preventing the removal of calcium by osteoclasts (a type of bone cell that destroys bone tissue). This prevents osteoclasts from breaking down the bone and keeps the bones strong and minimizes the risk of bones breaking.
A doctor or nurse will administer Zobone 4mg Injection 1's. In some cases, you may experience headache, fever, nausea, dizziness, vomiting, back pain, diarrhea, pain in the muscles, joints, or bones, swelling, or pain at the infusion site. Most of these side effects of Zobone 4mg Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Zobone 4mg Injection 1's or any other medicines, please tell your doctor. Avoid taking Zobone 4mg Injection 1's if you are pregnant or breastfeeding and consult a doctor. Zobone 4mg Injection 1's is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking Zobone 4mg Injection 1's if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. Drive only if you are alert as Zobone 4mg Injection 1's may cause dizziness. Zobone 4mg Injection 1's may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores, or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw.
Zobone 4mg Injection 1's contains Zoledronic acid used to treat postmenopausal osteoporosis, Paget’s disease, and hypercalcemia of malignancy (bone cancer in which excess of calcium exits). Zobone 4mg Injection 1's binds to the bone tightly and prevents calcium removal by osteoclasts (a type of bone cell that destroy bone tissue). This prevents osteoclasts from breaking down the bone, strengthening bones, and minimizing the risk of bones breaking. Also, Zobone 4mg Injection 1's may reduce calcium levels in the blood by preventing calcium reabsorption from bones to the blood. Thus, it helps in treating high calcium levels in the blood caused by cancer.
If you are allergic to Zobone 4mg Injection 1's or any other medicines, please tell your doctor. Avoid taking Zobone 4mg Injection 1's if you are pregnant or breastfeeding and consult a doctor. Zobone 4mg Injection 1's is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking Zobone 4mg Injection 1's if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. Drive only if you are alert as Zobone 4mg Injection 1's may cause dizziness. If you are not able to take daily calcium supplements, have had sections of the intestine or some or all of the parathyroid glands in the neck surgically removed, have cancer, gum disease, poor dental health, or planned tooth extraction or kidney problem, inform your doctor before taking Zobone 4mg Injection 1's. If you are a smoker, inform your doctor before receiving Zobone 4mg Injection 1's as it may increase the risk of dental problems. Zobone 4mg Injection 1's may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores, or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw. You are recommended to drink at least 2 glasses of fluids before and after treatment with Zobone 4mg Injection 1's as advised by your doctor to prevent dehydration. Take calcium and vitamin D supplements as prescribed by your doctor as Zobone 4mg Injection 1's may reduce calcium levels in the blood.
Drug-Drug Interaction: Zobone 4mg Injection 1's may interact with antibiotics (gentamicin) and water pills (furosemide).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: Avoid taking Zobone 4mg Injection 1's if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. If you have cancer, gum disease, poor dental health, or planned tooth extraction or kidney problem, inform your doctor before taking Zobone 4mg Injection 1's.
Osteoporosis: It is a bone disease that weakens and thins bones by decreasing bone density. As the density of bones decreases, they weaken and are more likely to break. Post-menopausal women are more likely to develop osteoporosis than men because, at menopause, women’s ovaries stop producing estrogen (a female hormone) essential to keeping bones healthy. Following menopause, bone loss occurs, making bones weak and more likely to break. Also, long-term use of steroids may affect bone strength and cause osteoporosis in both men and women. Signs and symptoms include back pain caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, and a bone that breaks much more easily than expected.
Paget’s disease: In Paget’s disease, bone remodeling (removal of old bone and replacement with new bone material) is too quick, and new bone is formed in a disordered manner making it weaker than normal. If left untreated, the bone may become deformed, painful, and broken.
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Alcohol
Caution
Interaction of alcohol with Zobone 4mg Injection 1's is unknown. Please consult a doctor before consuming alcohol with Zobone 4mg Injection 1's.
Pregnancy
Unsafe
Zobone 4mg Injection 1's is a category D pregnancy drug and is not recommended for pregnant women as it may harm an unborn baby. Please consult a doctor if you are pregnant.
Breast Feeding
Unsafe
Zobone 4mg Injection 1's is contraindicated in breastfeeding mothers. Therefore, please consult a doctor if you are breastfeeding.
Driving
Caution
Zobone 4mg Injection 1's may cause dizziness. Therefore, avoid driving or operating machinery if you feel dizzy after taking Zobone 4mg Injection 1's.
Liver
Caution
Take Zobone 4mg Injection 1's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
Caution
Take Zobone 4mg Injection 1's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Zobone 4mg Injection 1's if you have severe kidney problems.
Children
Unsafe
Zobone 4mg Injection 1's is not recommended for children below 18 years as the safety and effectiveness were not established.
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