Zofactum-1Gm Inj belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Zofactum-1Gm Inj does not work against infections caused by the virus, including cold and flu.

Zofactum-1Gm Inj is a combination of two antibiotics, namely: Cefoperazone (cephalosporin antibiotic) and sulbactam (beta-lactamase inhibitor). Cefoperazone works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria. On the other hand, sulbactam works by decreasing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, Zofactum-1Gm Inj helps to treat bacterial infections.

You may experience diarrhoea, allergic reaction, abnormal liver function tests, and anaemia (low number of red blood cells). Most of these side effects of Zofactum-1Gm Inj do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Zofactum-1Gm Inj, please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Zofactum-1Gm Inj on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Zofactum-1Gm Inj if you are pregnant or planning for pregnancy. Avoid taking Zofactum-1Gm Inj if you are breastfeeding as Zofactum-1Gm Inj may pass into breast milk. Avoid alcohol consumption while taking Zofactum-1Gm Inj to prevent unpleasant side-effects.

Zofactum-1Gm Inj belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Zofactum-1Gm Inj is a combination of two antibiotics, namely: Cefoperazone (cephalosporin antibiotic) and sulbactam (beta-lactamase inhibitor). Cefoperazone works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria. On the other hand, sulbactam works by decreasing bacterial resistance and enhancing the activity of cefoperazone against the bacteria. Together, Zofactum-1Gm Inj helps to treat bacterial infections.

• Diarrhoea
• Allergic reaction
• Abnormal liver function tests
• Anaemia (low number of red blood cells)

After taking Zofactum-1Gm Inj if you have allergy-like symptoms including rash, swelling of the face/lips/throat, difficulty in breathing, or tightness in the chest, immediately contact your doctor. Do not take Zofactum-1Gm Inj if you have an allergy to Zofactum-1Gm Inj, cephalosporins penicillin class of antibiotics as it may cause a skin rash, itching, and difficulty in breathing. People having liver disease or jaundice (yellowing of skin/eye) should not take Zofactum-1Gm Inj, as it can damage your liver severely. You may have diarrhoea in some cases which can be managed by taking it with any probiotics and plenty of fluids. Do not take antacids along with Zofactum-1Gm Inj; maintain a gap of 2-3 hours between both. Avoid alcohol consumption while taking Zofactum-1Gm Inj to prevent unpleasant side-effects. Zofactum-1Gm Inj may cause dizziness, so be cautious while driving. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side-effects.

Drug-Drug Interactions: Zofactum-1Gm Inj may have interaction with a diuretic (furosemide), anticoagulants (warfarin), other antibiotics (gentamicin).

Drug-Food Interactions: No interactions found/established.

Drug-disease interactions: Zofactum-1Gm Inj may have interactions with colitis (inflammation in the lining of the colon), seizures, dialysis, kidney, and liver dysfunction.

• FUROSEMIDE
• WARFARIN
• GENTAMICIN

• Probiotics should be taken after taking the full course of Zofactum-1Gm Inj in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help to restore the good bacteria of the intestine.
• Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet.
• Avoid intake of alcoholic beverages with Zofactum-1Gm Inj as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Zofactum-1Gm Inj in fighting off infections.

• Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat.
• Discontinue Zofactum-1Gm Inj and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
• Diarrhoea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
• Zofactum-1Gm Inj is preferably taken with food to avoid an upset stomach.
• Some people may be allergic to Zofactum-1Gm Inj or other penicillin or cephalosporin group of antibiotics. So a prior sensitivity test may be necessary. Inform your doctor if you are allergic to any medicine particularly antibiotics belong to these groups.
• If you feel nauseous after taking Zofactum-1Gm Inj, stick to simple meals like porridge, khichdi, dal roti, and other home-cooked meals. Avoid spicy and fatty food.

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly of spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.