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  3. Zonegran Tablet 10's

Zonegran Tablet 10's, Pack of 10 TABLETS
Zonegran Tablet 10's, Pack of 10 TABLETS
Zonegran Tablet 10's, Pack of 10 TABLETS
Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Composition :

ZONISAMIDE-100MG

Manufacturer/Marketer :

Eisai Pharmaceuticals India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zonegran Tablet

Zonegran Tablet belongs to a group of medicines called anti-convulsants or anti-epileptics used to treat epilepsy (seizures/fits). Epilepsy is a sudden rush of electricity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual’s consciousness, movements, or sensations.

Zonegran Tablet contains 'Zonisamide’ that reduces the abnormal and excessive activity of nerve impulses in the brain that cause fits or seizures. Thereby helps in controlling seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual’s consciousness, movements, or sensations. Zonegran Tablet is used alone or in combination to treat and prevent partial seizures in adults and children above 6 years of age.

Take Zonegran Tablet as prescribed by your doctor. You are advised to take Zonegran Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, irritability, loss of appetite, memory impairment, double vision, confusion, depression, constipation, nausea, headache, uncontrolled movements. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Zonegran Tablet for as long as your doctor has prescribed. Please do not stop taking Zonegran Tablet without consulting your doctor to avoid worsening of seizures. Do not take Zonegran Tablet if you are pregnant or planning for pregnancy unless prescribed by the doctor. Avoid taking Zonegran Tablet while breastfeeding as it may cause side-effects in the breastfed babies. Zonegran Tablet should not be given to children unless prescribed. Zonegran Tablet causes drowsiness and dizziness, so drive if you are alert. Zonegran Tablet should not be given to children unless prescribed. Avoid consuming alcohol along with Zonegran Tablet as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience mood swings or suicidal tendencies. Zonegran Tablet can cause permanent vision loss, inform your doctor immediately if you have any eye pain, redness, or any changes in your vision. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Zonegran Tablet

Epilepsy/Seizures

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Medicinal Benefits

Zonegran Tablet belongs to a group of medicines called anti-convulsants or anti-epileptics. Zonegran Tablet is used to treat epilepsy/seizures/fits. Epilepsy is a sudden rush of electricity in the brain. Zonegran Tablet works by blocking the sodium and calcium current in the brain and suppress the abnormal and excessive activity of nerve impulses in the brain that cause fits and pain. Thereby help in controlling seizures. Zonegran Tablet is used alone or in combination to treat and prevent partial seizures and generalized seizures in adults. Zonegran Tablet may be used as solo therapy or in combination in treating and preventing seizures in children above 6 years of age. Zonegran Tablet is not associated with any psychological or physical dependence, and there is no potential for abuse.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zonegran Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Managing Medication-Related Skin Allergies: A Step-by-Step Guide
  • If you experience signs of skin allergies such as redness, itching, or irritation after taking medication, contact your doctor right away.
  • To alleviate skin allergy symptoms, your doctor may change your medication regimen or offer tailored medication management advice.
  • Your doctor may recommend or prescribe drugs to relieve discomfort.
  • Cool compresses or calamine lotion can help relieve redness and itching on the afflicted skin area.
  • Staying hydrated by consuming plenty of water can help relieve discomfort.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.

Drug Warnings

Do not take Zonegran Tablet if you are allergic to Zonisamide or any of its contents. Avoid intake of Zonegran Tablet if you are pregnant or planning for pregnancy unless prescribed by the doctor. Breastfeeding mothers should consult the doctor before using Zonegran Tablet to pass into the breast milk and affect the baby. Zonegran Tablet should not be given to children unless prescribed. Inform your doctor before taking Zonegran Tablet if you have or had kidney and liver problems, glaucoma, high levels of ammonia, osteoporosis, depression, heart problems if you have low levels of bicarbonate in blood you have previously suffered from kidney stones. Do not stop taking Zonegran Tablet without consulting your doctor to avoid worsening of seizure episodes. Zonegran Tablet causes drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Zonegran Tablet as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience mood swings or suicidal tendencies. Zonegran Tablet can cause permanent vision loss, inform your doctor immediately if you have any eye pain, redness, or any changes in your vision.

Drug-Drug Interactions

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ZonisamideFlavoxate
Severe
ZonisamideQuetiapine
Severe

Drug-Drug Interactions

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ZonisamideFlavoxate
Severe
How does the drug interact with Zonegran Tablet:
Co-administration of Flavoxate and Zonegran Tablet may increase body temperature and decrease sweating.

How to manage the interaction:
If you are supposed to take Flavoxate and Zonegran Tablet together, a doctor may adjust the dose or monitor you more frequently to safely use both medications. Drink plenty of fluids during warm weather and when exercising and contact a doctor if you have decreased sweating or a fever. Avoid activities requiring mental alertness such as driving or operating hazardous machinery, until you know how the medications affect you. Do not discontinue any medication without consulting a doctor.
ZonisamideQuetiapine
Severe
How does the drug interact with Zonegran Tablet:
Coadministration of Quetiapine with Zonegran Tablet can increase the risk or severity of Zonegran Tablet side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Quetiapine with Zonegran Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
ZonisamideTrihexyphenidyl
Severe
How does the drug interact with Zonegran Tablet:
Coadministration of Trihexyphenidyl with Zonegran Tablet can increase the risk or severity of Zonegran Tablet side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Trihexyphenidyl with Zonegran Tablet together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
ZonisamideAmitriptyline
Severe
How does the drug interact with Zonegran Tablet:
Coadministration of Amitriptyline and Zonegran Tablet both increase body temperature while decreasing sweating.

How to manage the interaction:
Zonegran Tablet and Amitriptyline interact, however, if prescribed by a doctor, they can both be used. Some people may experience heat stroke and need to be hospitalized, especially in warm weather and while engaging in intense exercise. Children are especially at risk. If you feel sleepy, uneasy, or lightheaded after taking these medications combined, consult a doctor. Without consulting a doctor, never stop taking medicines.
ZonisamideSolifenacin
Severe
How does the drug interact with Zonegran Tablet:
Coadministration of Solifenacin with Zonegran Tablet can increase the risk or severity of Zonegran Tablet side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Solifenacin with Zonegran Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
ZonisamideAcetazolamide
Severe
How does the drug interact with Zonegran Tablet:
Co-administration of Acetazolamide with Zonegran Tablet may increase the risk or severity of metabolic acidosis (elevated levels of acid in the blood) and kidney stones.

How to manage the interaction:
Although there is a possible interaction between Acetazolamide and Zonegran Tablet, you can take these medicines together if prescribed by your doctor. If you experience symptoms such as fever, sudden back pain, abdominal pain, blood in the urine, tiredness, loss of appetite, irregular heartbeat, decreased sweating, trouble thinking clearly, and rapid breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ZonisamideClozapine
Severe
How does the drug interact with Zonegran Tablet:
Coadministration of Clozapine with Zonegran Tablet can increase the risk or severity of Zonegran Tablet side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Clozapine with Zonegran Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
ZonisamideClomipramine
Severe
How does the drug interact with Zonegran Tablet:
Co-administration of Clomipramine with Zonegran Tablet can increase the risk or severity of Zonegran Tablet

How to manage the interaction:
Taking Clomipramine with Zonegran Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
ZonisamideCyclobenzaprine
Severe
How does the drug interact with Zonegran Tablet:
Coadministration of Zonegran Tablet with Cyclobenzaprine can cause increased body temperature and decrease sweating.

How to manage the interaction:
Taking Cyclobenzaprine with Zonegran Tablet together is generally avoided as it can result in an interaction, it can be taken only if your doctor has advised it. However, if you experience changes in fever, shortness of breath, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
ZonisamidePropantheline
Severe
How does the drug interact with Zonegran Tablet:
Coadministration of Propantheline with Zonegran Tablet can increase the risk or severity of Zonegran Tablet side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Propantheline with Zonegran Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fay and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation, and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

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Author Details

Doctor image

Written By

Urvashi Bharti

MBBS

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:32 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Zonegran Tablet consists of 'zonisamide' that decreases the brain's excessive and abnormal nerve activity by blocking sodium and calcium currents in your brain and body. This reduces abnormal electrical activity between your nerve cells.

Consult your doctor before taking Zonegran Tablet if you are pregnant or planning for pregnancy. Your doctor will prescribe Zonegran Tablet only if the benefits outweigh the risks. If you are planning for pregnancy, use contraception while taking Zonegran Tablet .

Zonegran Tablet should be used with caution during hot weather as it may increase the chance of having a heat stroke. Inform your doctor if you have heat intolerance or fever. To avoid this condition, it is advisable to drink a lot of cold fluid and water, move to a cooler place, especially in summer.

No, Zonegran Tablet is not a habit-forming drug. However, it can cause side-effects, especially when you stop taking it suddenly.

Do not discontinue Zonegran Tablet without consulting your doctor. To treat your condition effectually continue taking Zonegran Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Zonegran Tablet ; your doctor will gradually reduce the dose to avoid precipitating seizures.

Consult your doctor before taking Zonegran Tablet if you have had kidney stones. Your doctor will prescribe Zonegran Tablet only if the benefits outweigh the risks. Zonegran Tablet should be taken with caution in patients with kidney stones. You may be at increased risk of developing more kidney stones. Reduce the risk of kidney stones, drink sufficient water.

Consult your doctor before taking Zonegran Tablet if you have glaucoma. Zonegran Tablet is contraindicated in patients with narrow-angle glaucoma. Zonegran Tablet may cause blindness on long-term use in the case of patients with narrow-angle glaucoma.

Drug-Drug Interactions Checker List

  • AMITRIPTYLINE
  • DULOXETINE
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  • FLUOXETINE
  • GABAPENTIN
  • LAMOTRIGINE
  • PREGABALIN
  • PHENYTOIN
  • TOPIRAMATE
  • ARIPIPRAZOLE
  • QUETIAPINE
  • LITHIUM
  • ALPRAZOLAM
  • ERYTHROMYCIN
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  • CHLORPHENIRAMINE
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  • TRAMADOL
  • MORPHINE
  • DIPHENHYDRAMINE
  • KETOCONAZOLE
  • ITRACONAZOLE
  • FLUCONAZOLE
  • TRIAZOLAM
  • TROLEANDOMYCIN
  • BROMPHENIRAMINE

Special Advise

  • Regular monitoring of bicarbonate levels while taking Zonegran Tablet is advised to prevent low blood bicarbonate levels.
  • Zonegran Tablet may cause low blood cell count, so if you have any red or purple spots on the body, let your doctor know about this.

Disease/Condition Glossary

Epilepsy: Epilepsy is a sudden rush of electricity in the brain. It is a disorder of the nervous system which occurs due to disturbed nerve cell activity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements, or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury, or stroke.

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