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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
COD available

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About Zonex Gel

Zonex Gel belongs to the class of medications called 'Non-steroidal anti-inflammatory drugs (NSAID)' used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure, or injury to the bones, joints, tendons, muscles, and ligaments. Osteoarthritis is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. 

Zonex Gel is a combination of six drugs: Diclofenac diethylamine, Capsaicin, Methyl salicylate, Linseed oil, Benzyl alcohol, and Menthol. Diclofenac diethylamine and Methyl salicylate are painkillers, which work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandin (PG). By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Capsaicin is a natural extract of chilli pepper that works by blocking the pain messengers to the nerves. Linseed oil possesses an anti-inflammatory agent that inhibits inflammatory mediators like leukotrienes (LK), reducing inflammation. On the other hand, Menthol and Benzyl alcohol are soothing and cooling agents which provide a cooling sensation by dilating the blood vessels, followed by an analgesic effect. It also enhances the penetration of drugs. Together, Zonex Gel helps provide relief from mild to moderate pain in various musculoskeletal and joint conditions. 

Zonex Gel is for external use only. In some cases, you may experience certain common side-effects such as application site reactions like itching, irritation, redness, and burning sensation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Zonex Gel can increase your risk of a fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Zonex Gel. Zonex Gel increases the chances of stomach ulcers and bleeding. Do not use Zonex Gel if you are pregnant or breastfeeding unless prescribed. Zonex Gel is not recommended for children below 14years as safety and efficacy have not been established. Avoid or limit exposure to natural or artificial sunlight as Zonex Gel may cause sensitivity. Do not use any other NSAIDs for pain relief along with Zonex Gel unless prescribed.

Uses of Zonex Gel

Pain and Inflammation associated with musculoskeletal and joint disorders.

Directions for Use

Zonex Gel is for external use only. Clean and dry the affected area. Take a pea-sized amount onto your finger and apply it directly onto the affected area. If it comes in contact with the eyes, nose, or mouth, rinse with water immediately.

Medicinal Benefits

Zonex Gel is a combination of Diclofenac diethylamine, Capsaicin, Methyl salicylate, Linseed oil, Benzyl alcohol, and Menthol. Zonex Gel is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain. Diclofenac diethylamine and Methyl salicylate work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins (PG). By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Capsaicin exerts an analgesic effect by blocking the pain messengers to the nerves. Linseed oil helps in reducing inflammation. Menthol and Benzyl alcohol provide a cooling sensation by dilating the blood vessels, followed by an analgesic effect. It also enhances the penetration of drugs. Together, Zonex Gel helps in providing relief from pain and inflammation. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zonex Gel

  • Itching
  • Irritation
  • Redness
  • Burning sensation

Drug Warnings

Do not use Zonex Gel if you are allergic to any of its contents. Inform your doctor in advance if you have/had severe heart problems, stomach ulcer or perforation, bleeding problems, bypass surgery, heart attack, blood circulation problems or inflammation of intestines. Do not use Zonex Gel if you experience asthma, urticaria, or allergy after taking a pain killer. Inform your doctor before using Zonex Gel if you are taking any painkillers orally. Do not use Zonex Gel if you are pregnant or breastfeeding unless prescribed. Zonex Gel is not recommended for children below 14years as the safety and effectiveness have not been established.

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Author Details

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FAQs

Zonex Gel consists of Diclofenac diethylamine, Capsaicin, Methyl salicylate, Linseed oil, Benzyl alcohol, and Menthol. It works by blocking the action of certain chemical messengers that cause pain and inflammation at the injured or damaged site.

Zonex Gel is used to reduce and relieve pain and inflammation associated with osteoarthritis. Osteoarthritis is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage.

Avoid taking a bath or shower for at least 1hour after applying Zonex Gel.

Avoid concomitant use of Zonex Gel with other topical products such as cosmetics, sunscreens, lotions, moisturizers, insect repellent creams, and other gels.

Do not apply external heat or cover the treated skin with dressings after applying Zonex Gel. Avoid wearing clothes or gloves for at least 10minutes after applying Zonex Gel.

Do not apply Zonex Gel on wounds, skin injuries, irritated skin, skin abrasions, and infections.

Please do not take any painkiller medicines and Zonex Gel to increase the risk of ulceration, perforation, and bleeding in the stomach and intestine. Inform your doctor before using Zonex Gel if you are taking any painkiller orally.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • WARFARIN
  • METHOTREXATE
  • CYCLOSPORINE

Special Advise

  • Do not apply on open wounds, cuts, abrasions or infected wounds.
  • Do not apply any bandages after application of Zonex Gel unless suggested by your doctor.

Disease/Condition Glossary

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, tendons, and nerves. It can be acute or chronic, can be localized or widespread. The pain can be mild or severe enough to interfere with your daily routine. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure, or injury to the bones, joints, tendons, muscles, and ligaments. Musculoskeletal pain symptoms include stiffness, swelling, redness, weakness, muscle spasms or twitching, trouble moving the affected area, soreness, cracking, or popping sound at the joints.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation, and tenderness. 

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