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  3. Zoylex 400mg Tablet DT

Zoylex 400mg Tablet DT, Pack of 1 Tablet
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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Whats That

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Composition :

ACYCLOVIR-400MG

Manufacturer/Marketer :

Vhb Life Sciences Inc

Consume Type :

ORAL

Return Policy :

Not Returnable

About Zoylex 400mg Tablet DT

Zoylex 400mg Tablet DT belongs to a class of antiviral medication used to treat viral infections such as cold sores (an inflamed blister in or near the mouth, caused by infection with the herpes simplex virus), genital herpes (a common sexually transmitted infection marked by genital pain and sores), and herpes zoster (a viral infection that causes a painful rash). In addition to this, it is also used to treat chickenpox. Zoylex 400mg Tablet DT does not cure herpes but prevents the infection spread and treats its symptoms.

Zoylex 400mg Tablet DT contains acyclovir, which is an antiviral medication. Zoylex 400mg Tablet DT prevents the multiplication of viruses in human cells by acting on its DNA, resulting in decreased viral overload. Zoylex 400mg Tablet DT kills or stops the growth of fungi and treats the infection.

The dose and duration will depend on your condition and how you respond to Zoylex 400mg Tablet DT. In some cases, you may experience headaches, dizziness, nausea, vomiting, diarrhoea, and sensitivity of the skin to sunlight. Most of these side effects of Zoylex 400mg Tablet DT are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Zoylex 400mg Tablet DT if you are allergic to acyclovir or any of its ingredients. Check with your doctor if you are pregnant, currently breastfeeding, or taking other prescribed or non-prescribed medicines. Use protection while having sexual intercourse to avoid the transfer of genital herpes (a sexually transmitted disease) to your partner. If you have a weak immune system, please inform your doctor before taking Zoylex 400mg Tablet DT as you may require a dose adjustment.

Uses of Zoylex 400mg Tablet DT

Herpes zoster (shingles), Genital herpes infection, Herpes labialis, Chicken Pox

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Oral Liquid: Take the prescribed dose by mouth using the measuring cup provided.

Medicinal Benefits

Zoylex 400mg Tablet DT contains acyclovir, which is an antiviral medication. Zoylex 400mg Tablet DT prevents the multiplication of viruses in human cells by acting on its DNA, resulting in decreased viral overload and preventing new viruses' formation. Zoylex 400mg Tablet DT is used to treat viral infections such as cold sores (an inflamed blister in or near the mouth, caused by infection with the herpes simplex virus), genital herpes (a common sexually transmitted infection marked by genital pain and sores), and herpes zoster (a viral infection that causes a painful rash). In addition to this, it is also used to treat chickenpox.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zoylex 400mg Tablet DT
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.

Drug Warnings

Do not take Zoylex 400mg Tablet DT if you are allergic to any of its ingredients. Inform your doctor about all other medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. If you are 65 years of age, have kidney disease or kidney transplant, have a heart problem or history of heart problems, have HIV/AIDS, are pregnant, or plan to become pregnant, Zoylex 400mg Tablet DT should be taken with caution and only if a doctor prescribes you. Zoylex 400mg Tablet DT may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, especially when you start taking Zoylex 400mg Tablet DT so please get up gradually. Also, do not drive a car or operate machinery requiring concentration as Zoylex 400mg Tablet DT may cause dizziness. Please do not take Zoylex 400mg Tablet DT if you have ever developed a rash due to a fever. If you have a weak immune system, please inform your doctor before taking Zoylex 400mg Tablet DT, as a dose adjustment may be required.

Drug-Drug Interactions

verifiedApollotooltip
AciclovirCidofovir
Critical
AciclovirEverolimus
Severe

Drug-Drug Interactions

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AciclovirCidofovir
Critical
How does the drug interact with Zoylex 400mg Tablet DT:
Co-administration of Cidofovir with Acyclovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Zoylex 400mg Tablet DT with Cidofovir is not recommended, please consult your doctor before taking it. You should consult a doctor if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, weakness, and palpitations. Do not stop using any medications without talking to a doctor.
AciclovirEverolimus
Severe
How does the drug interact with Zoylex 400mg Tablet DT:
Coadministration of Zoylex 400mg Tablet DT with Everolimus may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Zoylex 400mg Tablet DT with Everolimus together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience vomiting, irregular urination, sudden weight gain or loss, swelling, breathing difficulty, muscle pains, dizziness, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirTacrolimus
Severe
How does the drug interact with Zoylex 400mg Tablet DT:
Co-administration of Zoylex 400mg Tablet DT with tacrolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Coadministration of Zoylex 400mg Tablet DT with Tacrolimus can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without first consulting a doctor.
AciclovirMetrizamide
Severe
How does the drug interact with Zoylex 400mg Tablet DT:
Coadministration of Metrizamide in contrast with Zoylex 400mg Tablet DT may increase the risk or severity of kidney disorder.

How to manage the interaction:
Before undergoing any imaging procedure, let your doctor know you are on Zoylex 400mg Tablet DT treatment. Look out for signs such as vomiting, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, or weakness. Consult the doctor immediately.
AciclovirTizanidine
Severe
How does the drug interact with Zoylex 400mg Tablet DT:
Concomitant use of Zoylex 400mg Tablet DT with Tizanidine can increase the risk of developing low blood pressure.

How to manage the interaction:
Coadministration of Zoylex 400mg Tablet DT with Tizanidine can result in an interaction, but it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as dizziness, excessive sweating, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirTenofovir disoproxil
Severe
How does the drug interact with Zoylex 400mg Tablet DT:
Coadministration of Zoylex 400mg Tablet DT with Tenofovir Disoproxil may increase the risk or severity of kidney disorder.

How to manage the interaction:
Coadministration of Zoylex 400mg Tablet DT with Tenofovir disoproxil can result in an interaction, it can be taken when your doctor has advised it. Contact a doctor immediately if you experience decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AciclovirSirolimus
Severe
How does the drug interact with Zoylex 400mg Tablet DT:
Coadministration of Zoylex 400mg Tablet DT with Sirolimus may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Zoylex 400mg Tablet DT with Sirolimus can result in an interaction, it can be taken if your doctor has advised it. However, if you experience vomiting, a decrease in hunger, irregular urine, weight gain or loss, swelling, difficulty breathing, muscle pain, or weakness, consult a doctor.
AciclovirAmphotericin b
Severe
How does the drug interact with Zoylex 400mg Tablet DT:
Coadministration of Zoylex 400mg Tablet DT with Amphotericin B can increase the risk or severity of kidney disorder.

How to manage the interaction:
Taking Zoylex 400mg Tablet DT with Amphotericin b together can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you experience irregular urination, muscle ache, shortness if breath, or palpitations. Do not discontinue any medications without consulting a doctor.
AciclovirTenofovir alafenamide
Severe
How does the drug interact with Zoylex 400mg Tablet DT:
Coadministration of Zoylex 400mg Tablet DT with Tenofovir alafenamide may increase the risk or severity of kidney injury.

How to manage the interaction:
Taking Zoylex 400mg Tablet DT with tenofovir alafenamide can result in an interaction. However, if the benefits outweigh the risks, your doctor will prescribe them. Contact a doctor immediately if you experience symptoms such as decreased or increased urine output, sudden weight gain or loss, swelling, or shortness of breath. Do not discontinue any medication without consulting your doctor.
AciclovirIodamide
Severe
How does the drug interact with Zoylex 400mg Tablet DT:
Coadministration of Iodamide contrast with Zoylex 400mg Tablet DT may increase the risk or severity of kidney injury.

How to manage the interaction:
Before undergoing any imaging procedure let your doctor know you are on Zoylex 400mg Tablet DT treatment.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid alcoholic beverages with Zoylex 400mg Tablet DT as they can make you dehydrated and may affect your sleep.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil.
  • Include turmeric or yellow mustard in your diet to avoid constipation caused by antiviral drugs and increase the intake of fluids to stay hydrated.
  • Take enough Vitamin D and fresh air as it is known to improve the symptoms of herpes infection.
  • Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.
  • Eat a healthy and balanced diet, and make sure you sleep at least 8 hours daily for a speedy recovery.
  • If you are going in strong sunlight, please wear a lip balm SPF 50 or higher, as the Zoylex 400mg Tablet DT makes you sensitive to UV and sunlight.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Zoylex 400mg Tablet DT Substitute

Substitutes safety advice

Product Substitutes

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:44 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
ACYCLOVIR-400MGOther disorders of kidney and ureter, not elsewhere classified
Severe
ACYCLOVIR-400MGVolume depletion
Moderate

Drug-Diseases Interactions

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ACYCLOVIR-400MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Zoylex 400mg Tablet DT:
Acyclovir should be used with caution to patients who have impaired kidney function. In patients with moderate to severe renal impairment, dosage modifications are advised.

How to manage the interaction:
The use of Zoylex 400mg Tablet DT in kidney disease patients is not advised as it may increase the severity of kidney disease. Your doctor may adjust the dosing according to the severity of your kidney disease.
ACYCLOVIR-400MGVolume depletion
Moderate
How does the disease interact with Zoylex 400mg Tablet DT:
Patients who are dehydrated may be more susceptible to nephrotoxicity from using acyclovir. Acyclovir should be infused intravenously over the course of an hour, along with appropriate hydration.

How to manage the interaction:
Zoylex 400mg Tablet DT is excreted through the kidneys, dehydration may cause damage to kidney functions. Zoylex 400mg Tablet DT infusion over an hour is recommended in dehydrated patients. Urine output should be monitored.
ACYCLOVIR-400MGCare involving dialysis
Moderate
How does the disease interact with Zoylex 400mg Tablet DT:
Hemodialysis effectively removes acyclovir from the body. Following 6 hours of dialysis, it has been demonstrated that plasma levels of acyclovir decrease by 60%. After hemodialysis, acyclovir should be administered. If not, a second dosage might be administered following each hemodialysis session.

How to manage the interaction:
Patients undergoing hemodialysis should be given Zoylex 400mg Tablet DT after completing hemodialysis as hemodialysis removes 60% of Zoylex 400mg Tablet DT from the body.

FAQs

Zoylex 400mg Tablet DT works by killing or stopping the growth of the fungi. Thereby preventing the spread of infection.

No, you should not take Zoylex 400mg Tablet DT if you have HIV (Human Immunodeficiency Virus) infection. It can increase the risk of Thrombotic Thrombocytopenic Purpura (blood clot formation in small blood vessels).

No, Zoylex 400mg Tablet DT should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor.

If you miss a dose of Zoylex 400mg Tablet DT, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose. Do not take a double dose to make up for a missed one.

No, Zoylex 400mg Tablet DT does not cure herpes infection. Instead, it reduces pain and itching caused due to the infection and prevents a new sore formation.

Do not stop taking Zoylex 400mg Tablet DT without talking to your doctor. If you suddenly stop taking Zoylex 400mg Tablet DT, you may experience confusion, fever, mental state changes, or severe muscle stiffness. Your doctor will probably decrease your dose gradually depending upon your disease condition.

No, Zoylex 400mg Tablet DT is not known to affect contraception (condoms). Also, to avoid transmission of herpes infection as it is a sexually transmitted disease, please use any form of contraception.

Drug-Drug Interactions Checker List

  • PROBENECID
  • CIMETIDINE
  • AMINOPHYLLINE
  • THEOPHYLLINE
  • MYCOPHENOLATE MOFETIL

Special Advise

  • Use protection while having sexual intercourse to avoid the transfer of genital herpes (a sexually transmitted disease) to your partner.
  • Drinking plenty of fluid as Zoylex 400mg Tablet DT can cause dehydration and kidney damage.

Disease/Condition Glossary

Herpes zoster(shingles): It is a viral infection characterised by red skin rashes, pain and a burning sensation. The virus lives in the nervous system for years before causing Herpes. It can appear on the face, neck, torso, and one side of the body.

Genital herpes infection: It is a common sexually transmitted infection that affects the genitals. It can affect both men and women. Common symptoms include pain, irritation, itching, and sores in the genitals. It is marked by genital pain and sores.

Herpes labialis: It is a kind of viral infection that affects the lip. It is also known as cold sores. Symptoms include burning pain and small blisters. In some patients, it can also lead to fever.

Chickenpox: It is a viral infection that is highly contagious. Common symptoms include rash, small painful blisters, fever, sore throat, and body pain.

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