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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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Composition :

TADALAFIL-20MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zydalis MD 20 Tablet

Zydalis MD 20 Tablet belongs to the group of medicines called phosphodiesterase type 5 (PDE 5) inhibitors, primarily used to treat erectile dysfunction (impotence) and benign prostatic hyperplasia (BPH). Sometimes, Zydalis MD 20 Tablet is also used to treat pulmonary arterial  hypertension (high blood pressure in the lungs). Erectile dysfunction is the inability to keep a hard and erect penis suitable for sexual activity. Benign prostatic hyperplasia, also called as prostate enlargement, is the non-cancerous growth of the prostate gland.

Zydalis MD 20 Tablet contains ‘Tadalafil’, which works by relaxing the blood vessels in the penis; this allows the blood to flow into the penis when the person is sexually excited. Thereby, it helps to treat erectile dysfunction. Zydalis MD 20 Tablet relaxes the bladder and prostate muscles, thereby reducing enlarged prostate symptoms such as difficulty in urination and urgent need to urinate. Zydalis MD 20 Tablet used to treat pulmonary hypertension (high blood pressure in the lungs) by relaxing the blood vessels in the chest. Thereby increasing the blood supply to the lungs and decreasing the workload of the heart.

You are advised to take Zydalis MD 20 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, back pain, muscle pain, pain in the legs and arms, nasal congestion, indigestion, and facial flushing. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Do not take Zydalis MD 20 Tablet if you are taking nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension) or alpha-blockers; if you have heart problems or stroke, low blood pressure or uncontrolled high blood pressure. Zydalis MD 20 Tablet is not intended for use in women. Zydalis MD 20 Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Zydalis MD 20 Tablet should not be given to children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and the medicines you are taking to avoid unpleasant side-effects.

Uses of Zydalis MD 20 Tablet

Erectile dysfunction (impotence), benign prostatic hyperplasia (BPH), Pulmonary arterial hypertension (PAH)

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water as a whole. Do not crush, break or chew the tablet/capsule.Orally disintegrating tablet/strip: Keep the tablet/strip in the mouth and allow it to disintegrate. Do not swallow as a whole. Avoid handling the tablet/strip with wet hands.Jelly: Place the jelly in the mouth or under the tongue and allow it to dissolve.Mouth dissolving tablet: Place the tablet on the tongue and let it dissolve or disintegrate in the mouth without water.

Medicinal Benefits

Zydalis MD 20 Tablet belongs to the group of medicines called phosphodiesterase type 5 (PDE 5) inhibitors. Zydalis MD 20 Tablet is used to treat erectile dysfunction (impotence) and benign prostatic hyperplasia (BPH). Sometimes, Zydalis MD 20 Tablet is also used to treat pulmonary arterial  hypertension (high blood pressure in the lungs). Zydalis MD 20 Tablet works by relaxing the blood vessels in the penis; this allows the blood to flow into the penis when the person is sexually excited. Thereby, it helps to treat erectile dysfunction. Zydalis MD 20 Tablet relaxes the bladder and prostate muscles, thereby reducing enlarged prostate symptoms such as difficulty in urination and urgent need to urinate. Zydalis MD 20 Tablet used to treat pulmonary hypertension (high blood pressure in the lungs) by relaxing the blood vessels in the chest. Thereby, increasing the blood supply to the lungs and decreasing the workload of the heart.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zydalis MD 20 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Managing Medication-Related Skin Allergies: A Step-by-Step Guide
  • If you experience signs of skin allergies such as redness, itching, or irritation after taking medication, contact your doctor right away.
  • To alleviate skin allergy symptoms, your doctor may change your medication regimen or offer tailored medication management advice.
  • Your doctor may recommend or prescribe drugs to relieve discomfort.
  • Cool compresses or calamine lotion can help relieve redness and itching on the afflicted skin area.
  • Staying hydrated by consuming plenty of water can help relieve discomfort.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Managing Medication-Triggered Syncope (Loss of consciousness): A Step-by-Step Guide:
  • Let someone you trust know about your medication and the potential risk of loss of consciousness. Ask them to check on you regularly.
  • If you experience loss of consciousness or feel faint, call emergency services or have someone take you to the hospital.
  • Once you're receiving medical attention, inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your doctor may adjust your treatment plan by changing dosage, switching to a different medication, or stopping the medication.
  • Wear a medical alert device, such as a smartwatch or pendant, that can detect falls or other emergencies and alert emergency services.
  • If you're concerned about the risk of loss of consciousness, consult your doctor before it happens to develop a plan to mitigate the risk.
  • Talk to the doctor if you notice any visual disturbances.
  • Do not drive or operate machinery unless you have a clear vision.
  • Lubricate the eyes and use a warm compress to gently massage the eyes.
  • Keep your eyes protected from harmful sun rays by wearing sunglasses and a hat.
  • Rest well and eat a balanced diet.
  • Use a humidifier and increase fluid intake.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

Drug Warnings

Do not take Zydalis MD 20 Tablet if you are allergic to any of its contents; if you are taking nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension) or alpha-blockers; if you have heart problems or stroke, low blood pressure or uncontrolled high blood pressure, if you ever had a loss of vision. Inform your doctor if you have sickle cell anaemia (abnormal red blood cells), multiple myeloma (cancer of bone marrow), leukaemia (blood cell cancer), deformation in the penis, severe kidney or liver problems. Consult your doctor immediately if you experience loss of vision or hearing while taking Zydalis MD 20 Tablet. Zydalis MD 20 Tablet may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Zydalis MD 20 Tablet should not be given to children as safety and effectiveness have not been established.

Drug-Drug Interactions

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TadalafilAmyl nitrite
Critical

Drug-Drug Interactions

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How does the drug interact with Zydalis MD 20 Tablet:
Taking Zydalis MD 20 Tablet with Isosorbide dinitrate can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Isosorbide dinitrate with Zydalis MD 20 Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TadalafilAmyl nitrite
Critical
How does the drug interact with Zydalis MD 20 Tablet:
Taking Zydalis MD 20 Tablet with Amyl Nitrite can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Zydalis MD 20 Tablet with Amyl nitrite is generally avoided as it can lead to interaction. They can be taken only when advised by a doctor. Seek immediate medical attention if you experience symptoms like dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
TadalafilNitroprusside
Critical
How does the drug interact with Zydalis MD 20 Tablet:
Taking Zydalis MD 20 Tablet with Nitroprusside can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Zydalis MD 20 Tablet with Nitroprusside is generally avoided as it can lead to an interaction, but it can be taken if prescribed by a doctor. If you experience dizziness, or heart palpitations, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zydalis MD 20 Tablet:
Taking Zydalis MD 20 Tablet with Riociguat may increase the risk or severity of lower the blood pressure.

How to manage the interaction:
Taking Riociguat with Zydalis MD 20 Tablet is generally not recommended as it can lead to an interaction, but it can be taken together if prescribed by a doctor. However, if you experience dizziness, headache, and nasal congestion consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zydalis MD 20 Tablet:
Coadministration of Zydalis MD 20 Tablet with Isosorbide mononitrate can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Isosorbide mononitrate with Zydalis MD 20 Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zydalis MD 20 Tablet:
Using Zydalis MD 20 Tablet together with avanafil increases the risk or severity of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Zydalis MD 20 Tablet and Avanafil, you can take these medicines together if prescribed by a doctor. If you experience dizziness, or heart palpitations call a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zydalis MD 20 Tablet:
Coadministration of Miconazole with Zydalis MD 20 Tablet may increase blood levels and effects of Zydalis MD 20 Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between miconazole and Zydalis MD 20 Tablet, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience shortness of breath, dizziness, visual disturbances, or irregular heartbeat. Do not stop using medications without a doctor's advice.
TadalafilTelithromycin
Severe
How does the drug interact with Zydalis MD 20 Tablet:
Using Zydalis MD 20 Tablet with Telithromycin may significantly increase the blood levels and effects of Zydalis MD 20 Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Zydalis MD 20 Tablet with Telithromycin can result in an interaction, but it can be taken if a doctor has advised it. Contact a doctor if you experience shortness of breath, visual disturbances, hearing loss, or irregular heartbeat consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Zydalis MD 20 Tablet:
Coadministration of Ketoconazole with Zydalis MD 20 Tablet may increase the blood levels and effects of Zydalis MD 20 Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Ketoconazole and Zydalis MD 20 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if your condition worsens or you experience any symptoms like chest pain or tightness, irregular heartbeat, shortness of breath, consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Zydalis MD 20 Tablet:
Using Zydalis MD 20 Tablet together with voriconazole may significantly increase the blood levels and effects of Zydalis MD 20 Tablet. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Voriconazole and Zydalis MD 20 Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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TADALAFIL-20MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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TADALAFIL-20MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Drinking large amounts of grapefruit juice with Zydalis MD 20 Tablet may increase the blood levels and effects of Zydalis MD 20 Tablet. Avoid or limit drinking grapefruit juice while being treated with Zydalis MD 20 Tablet.

Diet & Lifestyle Advise

Erectile dysfunction:

  • Maintaining a healthy weight, eating a balanced diet, and regular exercising may help you manage erectile dysfunction. 
  • Avoid alcohol consumption as it may temporarily impair your ability to get an erection.
  • Avoid the usage of tobacco.
  • Share intimate time with your partner.
  • Stay sexually active to prevent further problems with erectile dysfunction.

Benign prostatic hyperplasia (BPH): 

  • Avoid foods like sugars, carbonated beverages, tea, citrus fruits, tomatoes, spicy foods, chocolate and tea. 
  • Limit fluid intake as excess fluid intake could cause an urge to urinate frequently.
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, and exercise regularly.
  • Quit smoking.
  • Take 6-8glasses or liquids every day.
  • Avoid processed foods. Instead, choose whole, unprocessed foods.
  • Include fruits, vegetables, and fibre-rich food in your diet.

Habit Forming

No

Therapeutic Class

PDE5-INHIBITORS, BPH AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Zydalis MD 20 Tablet works by relaxing the blood vessels in the penis, thereby allows the blood flow into the penis when the person is sexually excited.

Zydalis MD 20 Tablet relaxes the muscles in the bladder and prostate, thereby reduces the symptoms of benign prostatic hyperplasia (BPH) or enlarged prostate such as difficulty in urination and urgent need to urinate.

In some cases, Zydalis MD 20 Tablet is used to treat pulmonary arterial hypertension (high blood pressure in the lungs) by relaxing the chest's blood vessels. Thereby, increasing the blood supply to the lungs and decreasing the workload of the heart.

No, do not take Zydalis MD 20 Tablet with nitrates. Taking Zydalis MD 20 Tablet with medicines used to treat angina/chest pain, such as nitrates/nitroglycerin, may cause severe lowering of blood pressure. You are advised not to take Zydalis MD 20 Tablet if you are taking nitrates or have a history of heart attack/stroke.

No, Zydalis MD 20 Tablet should not be taken along with blood-pressure-lowering medicines. Zydalis MD 20 Tablet relaxes and widens the blood vessels; this causes a decrease in blood pressure. Therefore, if Zydalis MD 20 Tablet is taken with blood pressure lowering medicines, it could lead to a lowering of blood pressure.

Drug-Drug Interactions Checker List

  • AMLODIPINE
  • LISINOPRIL
  • LOSARTAN
  • METOPROLOL
  • RIOCIGAUT
  • NITROGLYCERIN
  • KETOCONAZOLE
  • ITRACONAZOLE
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • RIFAMPICIN
  • PHENOBARBITAL
  • PHENYTOIN
  • CARBAMAZEPINE
  • RITONAVIR

Special Advise

  • Take Zydalis MD 20 Tablet 30 minutes to 4 hours before sexual intercourse. However, it is best to take it an hour before sexual activity.
  • Do not take Zydalis MD 20 Tablet more than once a day. Take Zydalis MD 20 Tablet as prescribed by the doctor.
  • Talk to your doctor if the erection persists for greater than four hours.

Disease/Condition Glossary

Erectile dysfunction: It is the inability to keep a hard and erect penis suitable for sexual intercourse. It could be a sign of physical or psychological conditions such as fear of sexual failure, anxiety, depression, low self-esteem, or stress. Certain health-related factors such as smoking, drinking, being overweight, being physically inactive, and high blood pressure also contribute to erectile dysfunction. Symptoms of erectile dysfunction include difficulty in getting an erection, difficulty in maintaining the erection during intercourse and decreased sexual desire.

Benign prostatic hyperplasia (BPH): Benign prostatic hyperplasia, also called prostate enlargement, is the non-cancerous growth of the prostate gland due to the multiplication of cells. This leads to swelling and squeezing of the urethra and limits the urine flow. It is an age-associated prostate gland enlargement which can cause problems with urination. BPH symptoms include loss of bladder control, frequent urination, inability to urinate, incomplete bladder emptying, weak urinary stream, dribbling at the end of the urinary stream, sudden urge to urinate, and painful urination.

Pulmonary arterial hypertension (PAH): High blood pressure affects the arteries in the lungs and heart, leading to pulmonary arterial hypertension. It occurs due to narrowed or blocked blood vessels which increases the workload on the heart. Symptoms include chest pain, dizziness, fatigue, and swelling in the legs and ankles.

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