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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition

DICLOFENAC-75MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Zydiclo Injection 1ml

Zydiclo Injection 1ml belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAID) used to relieve pain in conditions such as flare-ups of joint and back pain, attacks of gout, pain caused by gall stones, kidney stones, injuries, trauma, fractures and pain following surgery. 
 
Zydiclo Injection 1ml contains ‘Diclofenac’, which works by inhibiting the synthesis of certain chemical messengers which are responsible for causing pain and inflammation. Thereby, Zydiclo Injection 1ml helps provide relief from pain.
 
Zydiclo Injection 1ml may cause common side effects such as stomach pain, nausea, vomiting, heartburn, and injection site reactions. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Zydiclo Injection 1ml is not recommended during the last three months of pregnancy and for children. Inform your doctor if you are pregnant or breastfeeding before receiving this injection. Keep your doctor informed about your health condition and ongoing medicines to rule out any side effects/interactions.

Uses of Zydiclo Injection 1ml

Pain relief

Directions for Use

Injection/infusion will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Zydiclo Injection 1ml belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAID) used to relieve pain in conditions such as flare-ups of joint and back pain, attacks of gout, pain caused by gall stones, kidney stones, injuries, trauma, fractures and pain following surgery. Zydiclo Injection 1ml contains ‘Diclofenac’, which works by inhibiting the synthesis of certain chemical messengers responsible for causing pain and inflammation. Thereby, Zydiclo Injection 1ml helps provide relief from pain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zydiclo Injection 1ml

  • Injection site reactions
  • Stomach pain
  • Heartburn
  • Nausea
  • Vomiting

Drug Warnings

Do not take Zydiclo Injection 1ml if you are allergic to any of its components; if you have/had gastric/peptic ulcer, active gastrointestinal bleeding, or coronary artery bypass graft surgery. Inform your doctor if you have/had heart problems, liver or kidney problems, heart attack, stroke, blood circulation problems, bowel disorders, bleeding problems, asthma, porphyria, angina, high blood pressure, high levels of fat, diabetes, or Lupus. Consult your doctor if you are pregnant or breastfeeding. Let your doctor know if you are taking any other medicines or supplements. NSAIDs may increase the risk of cardiovascular events, stroke, myocardial infarction, gastrointestinal bleeding, perforation, and ulceration. Hence, caution should be exercised.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacVorapaxar
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Zydiclo Injection 1ml:
Co-administration of Zydiclo Injection 1ml with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Zydiclo Injection 1ml is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacVorapaxar
Severe
How does the drug interact with Zydiclo Injection 1ml:
Taking Zydiclo Injection 1ml with Vorapaxar can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Zydiclo Injection 1ml and Vorapaxar, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacWarfarin
Severe
How does the drug interact with Zydiclo Injection 1ml:
Taking Zydiclo Injection 1ml with warfarin may, increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Zydiclo Injection 1ml and Warfarin, but they can be taken together if a doctor has prescribed them. However, consult your doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor. Do not discontinue any medications without consulting a doctor.
DiclofenacApixaban
Severe
How does the drug interact with Zydiclo Injection 1ml:
Co-administration of Zydiclo Injection 1ml and Apixaban may raise the risk of stomach bleeding.

How to manage the interaction:
Although there is a interaction between Zydiclo Injection 1ml and apixaban, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacBromfenac
Severe
How does the drug interact with Zydiclo Injection 1ml:
Taking Zydiclo Injection 1ml with bromfenac will have an additive effect and may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
There may be possible interaction between Zydiclo Injection 1ml and bromfenac but you can take it if prescribed by a doctor. Consult your doctor if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without first talking to your doctor.
DiclofenacRivaroxaban
Severe
How does the drug interact with Zydiclo Injection 1ml:
Co-administration of Rivaroxaban together with Zydiclo Injection 1ml may increase the risk of unsual bleeding.

How to manage the interaction:
Co-administration of Zydiclo Injection 1ml and Rivaroxaban can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacValdecoxib
Severe
How does the drug interact with Zydiclo Injection 1ml:
Taking Valdecoxib with Zydiclo Injection 1ml may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between Zydiclo Injection 1ml and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
DiclofenacDeferasirox
Severe
How does the drug interact with Zydiclo Injection 1ml:
Co-administration of Zydiclo Injection 1ml and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Zydiclo Injection 1ml and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacRamucirumab
Severe
How does the drug interact with Zydiclo Injection 1ml:
Co-administration of Zydiclo Injection 1ml and Ramucirumab can cause bleeding and ulcers.

How to manage the interaction:
Co-administration of Zydiclo Injection 1ml and Ramucirumab can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacIbuprofen
Severe
How does the drug interact with Zydiclo Injection 1ml:
Taking Zydiclo Injection 1ml and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Zydiclo Injection 1ml and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest and sleep well.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Stay hydrated, and drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Zydiclo Injection 1ml Substitute

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • WARFARIN
  • LITHIUM
  • METHOTREXATE
  • CICLOSPORIN
  • TACROLIMUS
  • TRIMETHOPRIM
  • MIFEPRISTONE
  • VORICONAZOLE
  • PHENYTOIN
  • CHOLESTYRAMINE

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, fractures, arthritis, and injury.

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