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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About ZYVEN OD 100MG TABLET

ZYVEN OD 100MG TABLET belongs to a group of medications called 'antidepressants' used to treat a major depressive disorder (depression). Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. Symptoms include sadness, loss of interest, appetite changes, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty concentrating, making decisions, and thinking.
 
ZYVEN OD 100MG TABLET contains desvenlafaxine, which works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance and helps in regulating mood, and treats depression. 
 
You are advised to take ZYVEN OD 100MG TABLET for as long as your doctor has prescribed it for you, depending on your medical condition and response to the treatment. In some cases, you may experience certain common side-effects such as nausea, dizziness, insomnia (sleep problems), constipation, sleepiness, loss of appetite, anxiety and male sexual dysfunction disorders. Talk to your doctor if you experience these side-effects persistently.
 
Please do not stop taking ZYVEN OD 100MG TABLET suddenly, as it might cause withdrawal symptoms. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Consult your doctor if you are pregnant or breastfeeding. Avoid driving as ZYVEN OD 100MG TABLET may cause sleepiness and dizziness. ZYVEN OD 100MG TABLET should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with ZYVEN OD 100MG TABLET as it could lead to increased sleepiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of ZYVEN OD 100MG TABLET

Depression

Directions for Use

Take ZYVEN OD 100MG TABLET with or without food. Swallow ZYVEN OD 100MG TABLET as a whole with a glass of water, do not chew or crush it.

Medicinal Benefits

ZYVEN OD 100MG TABLET belongs to a group of antidepressant medicines indicated for the treatment of a major depressive disorder. ZYVEN OD 100MG TABLET works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain. This maintains mental balance and helps in regulating mood, and treats depression. 

Storage

Store in a cool and dry place away from sunlight
Side effects of Zyven OD 100 Tablet
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.

Drug Warnings

Do not take ZYVEN OD 100MG TABLET if you are allergic to any of its contents; if you are taking linezolid, intravenous methylene blue, other serotonergic agents, monoamine oxidase inhibitors (MAOI) or have taken them in the last 14 days. Inform your doctor before taking ZYVEN OD 100MG TABLET if you have heart problems, hypotension, bipolar disorder, glaucoma, epilepsy, lung or breathing problems, bleeding problems, or low sodium levels in the blood. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Consult your doctor if you are pregnant or breastfeeding. ZYVEN OD 100MG TABLET should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with ZYVEN OD 100MG TABLET as it could lead to increased sleepiness and dizziness. 

Drug-Drug Interactions

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DesvenlafaxineRasagiline
Critical
DesvenlafaxineTranylcypromine
Critical

Drug-Drug Interactions

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DesvenlafaxineRasagiline
Critical
How does the drug interact with Zyven OD 100 Tablet:
Taking rasagiline with Zyven OD 100 Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Zyven OD 100 Tablet with Rasagiline together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DesvenlafaxineTranylcypromine
Critical
How does the drug interact with Zyven OD 100 Tablet:
Taking tranylcypromine with Zyven OD 100 Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Tranylcypromine and Zyven OD 100 Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DesvenlafaxineProcarbazine
Critical
How does the drug interact with Zyven OD 100 Tablet:
Combining Procarbazine and Zyven OD 100 Tablet can increase the risk of a rare but serious condition called the serotonin syndrome.(A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Procarbazine and Zyven OD 100 Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, contact your doctor immediately. you should wait at least 14 days after stopping isocarboxazid before you start treatment with Zyven OD 100 Tablet and do not discontinue any medications without first consulting your doctor.
DesvenlafaxineSafinamide
Critical
How does the drug interact with Zyven OD 100 Tablet:
Taking Safinamide with Zyven OD 100 Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Zyven OD 100 Tablet with Safinamide is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
DesvenlafaxineIsocarboxazid
Critical
How does the drug interact with Zyven OD 100 Tablet:
Combining Isocarboxazid and Zyven OD 100 Tablet might raise serotonin hormone levels in the body and may affect the brain or nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Isocarboxazid and Zyven OD 100 Tablet together is generally avoided as it can lead to an interaction, it can be taken only if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DesvenlafaxineAmoxapine
Severe
How does the drug interact with Zyven OD 100 Tablet:
The combined use of Amoxapine and Zyven OD 100 Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Co-administration of Amoxapine and Zyven OD 100 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, Increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
DesvenlafaxinePhenelzine
Severe
How does the drug interact with Zyven OD 100 Tablet:
Co-administration of Phenelzine and Zyven OD 100 Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Co-administration of Phenelzine and Zyven OD 100 Tablet can lead to interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
DesvenlafaxineEscitalopram
Severe
How does the drug interact with Zyven OD 100 Tablet:
Coadministration of Escitalopram and Zyven OD 100 Tablet might raise serotonin hormone levels in the body and may affect the brain or nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Although there is an interaction between escitalopram and Zyven OD 100 Tablet, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucinations (seeing and hearing things that do not exist), increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
DesvenlafaxineLithium succinate
Severe
How does the drug interact with Zyven OD 100 Tablet:
Coadministration of Lithium with Zyven OD 100 Tablet may increase the levels and side effects of Zyven OD 100 Tablet.

How to manage the interaction:
Although there is a possible interaction between Zyven OD 100 Tablet and Lithium succinate, you can take these medicines together if prescribed by your doctor. However, if you experience Headache, nausea, vomiting, diarrhea, constipation, dry mouth, increased sweating, decreased appetite, tremor, feeling nervous, restless, fatigue, or having trouble sleeping (insomnia), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not stop using any medications without first talking to your doctor.
DesvenlafaxineDoxepin
Severe
How does the drug interact with Zyven OD 100 Tablet:
Co-administration of doxepin and Zyven OD 100 Tablet might raise serotonin hormone levels in the body and may affect the brain or nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Co-administration of doxepin and Zyven OD 100 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhea, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega-fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
  • Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help in the proper maintenance of neurotransmitters. 
  • Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
  • Exercising helps in the production of the body’s natural antidepressants. It also helps in relieving stress, improves mood, boosts self-esteem, and provides restful sleep.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

ZYVEN OD 100MG TABLET works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain which maintain mental balance, thereby regulating mood that treats depression.

Do not discontinue ZYVEN OD 100MG TABLET without consulting your doctor, as it could lead to withdrawal symptoms. To treat your condition effectually, continue taking ZYVEN OD 100MG TABLET for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking ZYVEN OD 100MG TABLET.

ZYVEN OD 100MG TABLET may cause decreased sex-drive (libido), problems with ejaculation and orgasm. Consult your doctor if you have any concerns regarding this.

Hypertension should be controlled before starting treatment with ZYVEN OD 100MG TABLET. Therefore, consult your doctor if you have high blood pressure. Regular monitoring of blood pressure levels is advised while taking ZYVEN OD 100MG TABLET.

ZYVEN OD 100MG TABLET may increase the chances of bleeding and bruising. The risk increases when ZYVEN OD 100MG TABLET is taken along with painkillers and blood thinners. Consult your doctor if you notice unusual bleeding or bruising.

When taken along with other medicines, ZYVEN OD 100MG TABLET may cause rare but potentially life-threatening condition called serotonin syndrome. This condition causes changes in how the brain, blood vessels, muscles and digestive system work. Avoid taking ZYVEN OD 100MG TABLET along with MAOI’s (used to treat depression), linezolid, intravenous methylene blue and other serotonergic agents.

ZYVEN OD 100MG TABLET may dilate your pupils (widen the dark centres of your eyes). This can trigger a glaucoma attack. Before taking ZYVEN OD 100MG TABLET, consult your doctor if you have glaucoma.

ZYVEN OD 100MG TABLET may cause seizures. If you’ve ever had a seizure, tell your doctor before taking ZYVEN OD 100MG TABLET.

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • LURASIDONE
  • QUETIAPINE
  • AMPHETAMINE
  • DEXTROAMPHETAMINE
  • AMITRIPTYLINE
  • BUPROPION
  • DULOXETINE
  • ESCITALOPRAM
  • SERTRALINE
  • TRAZODONE
  • VENLAFAXINE
  • CLONAZEPAM
  • LAMOTRIGINE
  • PREGABALIN
  • CYCLOBENZAPRINE
  • IBUPROFEN
  • TRAMADOL
  • ALPRAZOLAM
  • CETIRIZINE
  • PHENTERMINE
  • LISDEXAMFETAMINE

Special Advise

  • Do not stop taking ZYVEN OD 100MG TABLET suddenly as it might cause withdrawal symptoms.
  • Consult your doctor immediately if you have suicidal thoughts such as killing or harming yourself.
  • Talk to your doctor right away if you notice any unusual bleeding or bruising.

Disease/Condition Glossary

Major depressive disorder: Major depressive disorder, also known as clinical depression, is a mental health disorder characterised by a persistent and intense feeling of sadness for an extended duration of time. It mainly impacts mood, behaviour, and other physical functions, such as sleep and appetite. Symptoms include sadness, loss of interest, appetite changes, sleep problems, restlessness, lack of energy, feeling worthless or guilty, thoughts of harming oneself, difficulty in concentrating, making decisions, and thinking. The exact cause of depression is unknown. However, factors such as stress, changes in hormone levels, alcohol or drug abuse, abuse during childhood, certain medical conditions and medications might increase the risk of developing depression.

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