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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Manufacturer/Marketer

Macleods Pharmaceuticals Ltd.

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Alkarate Syrup 100 ml

Alkarate Syrup 100 ml is a urinary alkaliser indicated for the treatment of renal tubular acidosis, gout and kidney stones. Kidney stones are small, hard deposits made up of calcium, phosphate and other minerals/acid salts that stick together in concentrated urine. Renal tubular acidosis is a condition in which the kidneys fail to excrete acids into the urine; this causes the blood to remain too acidic.
 
Alkarate Syrup 100 ml contains disodium hydrogen citrate, which metabolises to bicarbonate and increases the excretion of free bicarbonate ions; this increases the solubility of cysteine in the urine and ionises uric acid to soluble urate ion. This helps in increasing the urinary pH, thereby makes the urine less acidic. 
 
You are advised to take Alkarate Syrup 100 ml for as long as your doctor has suggested it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as abdominal discomfort, diarrhoea, tiredness, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Alkarate Syrup 100 ml if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Alkarate Syrup 100 ml. It is not known if Alkarate Syrup 100 ml affects your ability to drive; drive only if you are alert. Talk to a doctor before giving Alkarate Syrup 100 ml to children. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Alkarate Syrup 100 ml

Renal tubular acidosis, Kidney stones.

Directions for Use

The suggested dose of Alkarate Syrup 100 ml should be diluted with a glass of water and taken after meals. Depending on your medical condition, your doctor will decide how long you need to take Alkarate Syrup 100 ml.

Medicinal Benefits

Alkarate Syrup 100 ml is a urinary alkaliser indicated for the treatment of renal tubular acidosis, gout and kidney stones. Alkarate Syrup 100 ml contains disodium hydrogen citrate, which metabolises to bicarbonate and increases the excretion of free bicarbonate ions; this increases the solubility of cysteine in the urine and ionises uric acid to soluble urate ion. This helps in increasing the urinary pH, thereby makes the urine less acidic. Alkarate Syrup 100 ml may also help to treat urinary tract infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Alkarate Syrup 100 ml

  • Abdominal discomfort
  • Diarrhoea
  • Tiredness
  • Vomiting
  • Nausea

Drug Warnings

Do not take Alkarate Syrup 100 ml if you are allergic to any of its contents. Inform your doctor if you have hyperkalaemia (high levels of potassium), hypocalcaemia (low blood calcium levels), high blood pressure, oedema, increased alkalinity in the blood, urinary tract infection, or kidney dysfunction. Consult your doctor before taking Alkarate Syrup 100 ml if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Alkarate Syrup 100 ml. It is not known if Alkarate Syrup 100 ml affects your ability to drive; drive only if you are alert. Talk to a doctor before giving Alkarate Syrup 100 ml to children.

Drug-Drug Interactions

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Sodium citrateAluminium hydroxide
Severe
Sodium citrateLevofloxacin
Severe

Drug-Drug Interactions

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Sodium citrateAluminium hydroxide
Severe
How does the drug interact with Alkarate Syrup 100 ml:
Co-administration of Aluminium hydroxide and Alkarate Syrup 100 ml may increase aluminum levels and risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Alkarate Syrup 100 ml and Aluminium hydroxide, you can take these medicines together if prescribed by your doctor. However, if you experience symptoms like severe stomach pain, constipation, loss of appetite, pain when you urinate, muscle weakness, tiredness nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Sodium citrateLevofloxacin
Severe
How does the drug interact with Alkarate Syrup 100 ml:
Co-administration of Levofloxacin and Alkarate Syrup 100 ml together may increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Alkarate Syrup 100 ml and Levofloxacin, you can take these medicines together if prescribed by a doctor. However, if you experience flank pain, painful urination, or blood in the urine, consult the doctor. It is advised to drink plenty of fluids during treatment with Levofloxacin. Do not stop using any medications without talking to a doctor.
Sodium citrateDoxycycline
Severe
How does the drug interact with Alkarate Syrup 100 ml:
Coadministration of Alkarate Syrup 100 ml with Doxycycline can reduce the effectiveness of Doxycycline.

How to manage the interaction:
Although taking Alkarate Syrup 100 ml with Doxycycline can possibly result in decreased efficacy, they can be taken together if prescribed by a doctor. It is advised to separate Alkarate Syrup 100 ml and doxycycline by three to four hours. Do not stop using any medications without consulting a doctor.
Sodium citrateDihydroxialumini sodium carbonate
Severe
How does the drug interact with Alkarate Syrup 100 ml:
Co-administration of Dihydroxialumini sodium carbonate and Alkarate Syrup 100 ml may increase aluminum levels and risk of developing side effects.

How to manage the interaction:
Although taking Alkarate Syrup 100 ml and Dihydroxialumini sodium carbonate together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience severe stomach pain, constipation, loss of appetite, pain when you urinate, tiredness, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids as they help in flushing out excess minerals.
  • Limit salt intake. High amounts of salt can increase the risk of kidney stones.
  • Maintain a healthy weight by exercising regularly.
  • Avoid foods rich in oxalates such as spinach, nuts, okra, dates, avocado, hot chocolate, cocoa, baked potato, French fries, and cereals, as they might increase the risk of oxalate stones.

Habit Forming

No

Therapeutic Class

RENAL AND GENITOURINARY AGENT

Alkarate Syrup 100 ml Substitute

Substitutes safety advice
  • Cital Oral Liquid 100 ml

    by Others

    1.05per tablet
  • Cital Sugar Free Oral Liquid 200 ml

    by Others

    0.90per tablet
  • Citrahil Syrup 100 ml

    by Others

    1.02per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • TETRACYCLINE
  • QUINIDINE
  • EPHEDRINE
  • PSEUDOEPHEDRINE

Special Advise

  • Alkarate Syrup 100 ml might interfere with urine ketone test. Inform the person doing the test that you are taking Alkarate Syrup 100 ml.

Disease/Condition Glossary

Kidney stones: Nephrolithiasis, also known as kidney stones, is a disease affecting the urinary tract. Kidney stones are small, hard deposits made up of calcium, phosphate and other minerals/acid salts that stick together in concentrated urine. They are the common cause of blood in urine and can be painful when passing through the urinary tract. Symptoms include severe pain, usually in one side of the abdomen and nausea. 

Renal tubular acidosis: It is a condition that involves the accumulation of acid in the body due to the failure of the kidneys to alkalise the urine appropriately. The kidneys fail to excrete acids into the urine, which causes the blood to remain too acidic. If not treated, it could lead to kidney stones, bone disease, kidney disease or failure.

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