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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Alkarate Syrup

Alkarate Syrup is a urinary alkaliser indicated for the treatment of renal tubular acidosis, gout and kidney stones. Kidney stones are small, hard deposits made up of calcium, phosphate and other minerals/acid salts that stick together in concentrated urine. Renal tubular acidosis is a condition in which the kidneys fail to excrete acids into the urine; this causes the blood to remain too acidic.
 
Alkarate Syrup contains disodium hydrogen citrate, which metabolises to bicarbonate and increases the excretion of free bicarbonate ions; this increases the solubility of cysteine in the urine and ionises uric acid to soluble urate ion. This helps in increasing the urinary pH, thereby makes the urine less acidic. 
 
You are advised to take Alkarate Syrup for as long as your doctor has suggested it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as abdominal discomfort, diarrhoea, tiredness, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Alkarate Syrup if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Alkarate Syrup . It is not known if Alkarate Syrup affects your ability to drive; drive only if you are alert. Talk to a doctor before giving Alkarate Syrup to children. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Alkarate Syrup

Renal tubular acidosis, Kidney stones.

Directions for Use

The suggested dose of Alkarate Syrup should be diluted with a glass of water and taken after meals. Depending on your medical condition, your doctor will decide how long you need to take Alkarate Syrup .

Medicinal Benefits

Alkarate Syrup is a urinary alkaliser indicated for the treatment of renal tubular acidosis, gout and kidney stones. Alkarate Syrup contains disodium hydrogen citrate, which metabolises to bicarbonate and increases the excretion of free bicarbonate ions; this increases the solubility of cysteine in the urine and ionises uric acid to soluble urate ion. This helps in increasing the urinary pH, thereby makes the urine less acidic. Alkarate Syrup may also help to treat urinary tract infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Alkarate Syrup

  • Abdominal discomfort
  • Diarrhoea
  • Tiredness
  • Vomiting
  • Nausea

Drug Warnings

Do not take Alkarate Syrup if you are allergic to any of its contents. Inform your doctor if you have hyperkalaemia (high levels of potassium), hypocalcaemia (low blood calcium levels), high blood pressure, oedema, increased alkalinity in the blood, urinary tract infection, or kidney dysfunction. Consult your doctor before taking Alkarate Syrup if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Alkarate Syrup . It is not known if Alkarate Syrup affects your ability to drive; drive only if you are alert. Talk to a doctor before giving Alkarate Syrup to children.

Drug-Drug Interactions

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Sodium citrateLevofloxacin
Severe
Sodium citrateDihydroxialumini sodium carbonate
Severe

Drug-Drug Interactions

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Sodium citrateLevofloxacin
Severe
How does the drug interact with Alkarate Syrup 100 ml:
Co-administration of Levofloxacin and Alkarate Syrup 100 ml together may increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Alkarate Syrup 100 ml and Levofloxacin, you can take these medicines together if prescribed by a doctor. However, if you experience flank pain, painful urination, or blood in the urine, consult the doctor. It is advised to drink plenty of fluids during treatment with Levofloxacin. Do not stop using any medications without talking to a doctor.
Sodium citrateDihydroxialumini sodium carbonate
Severe
How does the drug interact with Alkarate Syrup 100 ml:
Co-administration of Dihydroxialumini sodium carbonate and Alkarate Syrup 100 ml may increase aluminum levels and risk of developing side effects.

How to manage the interaction:
Although taking Alkarate Syrup 100 ml and Dihydroxialumini sodium carbonate together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience severe stomach pain, constipation, loss of appetite, pain when you urinate, tiredness, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Sodium citrateAluminium hydroxide
Severe
How does the drug interact with Alkarate Syrup 100 ml:
Co-administration of Aluminium hydroxide and Alkarate Syrup 100 ml may increase aluminum levels and risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Alkarate Syrup 100 ml and Aluminium hydroxide, you can take these medicines together if prescribed by your doctor. However, if you experience symptoms like severe stomach pain, constipation, loss of appetite, pain when you urinate, muscle weakness, tiredness nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Sodium citrateDoxycycline
Severe
How does the drug interact with Alkarate Syrup 100 ml:
Coadministration of Alkarate Syrup 100 ml with Doxycycline can reduce the effectiveness of Doxycycline.

How to manage the interaction:
Although taking Alkarate Syrup 100 ml with Doxycycline can possibly result in decreased efficacy, they can be taken together if prescribed by a doctor. It is advised to separate Alkarate Syrup 100 ml and doxycycline by three to four hours. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids as they help in flushing out excess minerals.
  • Limit salt intake. High amounts of salt can increase the risk of kidney stones.
  • Maintain a healthy weight by exercising regularly.
  • Avoid foods rich in oxalates such as spinach, nuts, okra, dates, avocado, hot chocolate, cocoa, baked potato, French fries, and cereals, as they might increase the risk of oxalate stones.

Habit Forming

No

Therapeutic Class

RENAL AND GENITOURINARY AGENT

Alkarate Syrup Substitute

Substitutes safety advice
  • Cital Oral Liquid 100 ml

    by Others

    1.05per tablet
  • Cital Sugar Free Oral Liquid 200 ml

    by Others

    0.90per tablet
  • Oricitral Lemon Syrup 100 ml

    by Others

    0.85per tablet
  • ALKAMED SYRUP 100ML

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    0.99per tablet
  • Alkorina Liquid 100 ml

    by Others

    1.15per tablet

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Alkarate Syrup raises the urinary pH, thereby makes the urine less acidic. This helps the kidneys to get rid of excess uric acid, and prevents gout and the formation of kidney stones.

Consult your doctor before taking corticosteroids with Alkarate Syrup as it might increase the blood sodium levels.

Alkarate Syrup contains sodium; therefore, talk to your doctor before taking Alkarate Syrup if you are on a sodium-restricted diet or if you have high blood pressure.

To treat your condition effectually, continue taking Alkarate Syrup for as long as suggested. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Alkarate Syrup .

Diarrhoea might be a side-effect of Alkarate Syrup . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Consult a doctor before taking Alkarate Syrup if you have an active urinary tract infection, as Alkarate Syrup increases the urinary pH, which might promote further bacterial growth.

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • TETRACYCLINE
  • QUINIDINE
  • EPHEDRINE
  • PSEUDOEPHEDRINE

Special Advise

  • Alkarate Syrup might interfere with urine ketone test. Inform the person doing the test that you are taking Alkarate Syrup .

Disease/Condition Glossary

Kidney stones: Nephrolithiasis, also known as kidney stones, is a disease affecting the urinary tract. Kidney stones are small, hard deposits made up of calcium, phosphate and other minerals/acid salts that stick together in concentrated urine. They are the common cause of blood in urine and can be painful when passing through the urinary tract. Symptoms include severe pain, usually in one side of the abdomen and nausea. 

Renal tubular acidosis: It is a condition that involves the accumulation of acid in the body due to the failure of the kidneys to alkalise the urine appropriately. The kidneys fail to excrete acids into the urine, which causes the blood to remain too acidic. If not treated, it could lead to kidney stones, bone disease, kidney disease or failure.

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