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  1. Home
  2. OTC

  3. Clindoxyl Gel 10 gm

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About Clindoxyl Gel

Clindoxyl Gel belongs to the class of dermatological preparations called ‘antiacne’ used to treat acne (pimples) and kill bacteria, causing acne. Acne is a common skin condition and occurs when hair follicles are blocked with dead skin cells and oil. The acne-causing bacteria feeds on sebum (natural oil produced by skin) causing redness and swelling.

Clindoxyl Gel is a combination of two drugs: Clindamycin (antibiotic) and Benzoyl peroxide (keratolytic agent). Clindamycin belongs to the class of antibiotics that inhibits the production of essential proteins that are necessary for bacteria to grow, multiply and increase in numbers. Thereby, stops or slows down the growth of bacteria and clears acne. Benzoyl peroxide is a keratolytic agent that breaks down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Thereby, helps in reducing blackheads and whiteheads. Additionally, Benzoyl peroxide possesses antibacterial properties and kills bacteria that cause acne, and reduces inflamed acne spots.

Use Clindoxyl Gel as prescribed. Clindoxyl Gel is only for external use. Avoid contact of Clindoxyl Gel with nose, ears, mouth, or eyes. In case Clindoxyl Gel comes in contact with these areas accidentally, rinse with warm water thoroughly. Your doctor will advise you how often you take Clindoxyl Gel based on your medical condition. In some cases, you may experience skin peeling, dry skin, pain, redness, itching, or burning sensation at the site of application. Most of these side effects of Clindoxyl Gel do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Clindoxyl Gel or any other medicines, please tell your doctor. Do not apply Clindoxyl Gel to cuts, open wounds, broken, sunburnt, or sensitive skin areas. Avoid sun exposure while using Clindoxyl Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking Clindoxyl Gel. Do not apply Clindoxyl Gel in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects such as redness, irritation, skin peeling, or discomfort. If you have intestine problems, ulcerative colitis (inflammation and sores in the digestive tract), or if you ever had severe diarrhoea caused by any antibiotic medicine, please inform your doctor before taking Clindoxyl Gel. 

Uses of Clindoxyl Gel

Acne (pimples)

Medicinal Benefits

Clindoxyl Gel is a combination of two drugs: Clindamycin and Benzoyl peroxide used to treat acne (pimples). Clindamycin is a broad-spectrum antibiotic that acts against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. The acne-causing bacteria feeds on sebum produced by sebaceous (oil) glands in the skin and produce fatty acids and waste products that irritate oil glands, causing redness and swelling. Clindamycin inhibits the production of essential proteins necessary for bacteria to grow, multiply and increase in numbers. Thereby, stops or slows down the growth of bacteria and clears acne. Benzoyl peroxide is a keratolytic agent that breaks down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Thereby, helps in reducing blackheads and whiteheads. Additionally, Benzoyl peroxide possesses antibacterial properties and kills bacteria that causes acne and reduces inflamed acne spots. 

Directions for Use

Wash your hands before and after applying Clindoxyl Gel. Before using it, wash the affected area with warm water. Apply a small amount of Clindoxyl Gel as a thin layer and gently rub on the clean and dry affected area of the skin in the evening. Clindoxyl Gel is only for external use. If you are using Clindoxyl Gel on face, avoid contact with eyes as it may cause irritation. In case Clindoxyl Gel comes in contact with eyes accidentally, rinse with water thoroughly. If you still have a problem with your eye or notice any vision problems, consult your doctor immediately.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clindoxyl Gel

  • Dry skin
  • Skin peeling
  • Skin itching
  • Skin redness
  • Pain or burning sensation of the skin

Drug Warnings

If you are known to be allergic to Clindoxyl Gel or any other medicines, please tell your doctor. Do not apply Clindoxyl Gel to cuts, open wounds, broken, sunburnt, or sensitive skin areas. Do not swallow Clindoxyl Gel. In case of accidental swallowing, please consult a doctor. Avoid contact of Clindoxyl Gel with nose, ears, mouth, or eyes. In case Clindoxyl Gel comes in contact with these areas accidentally, rinse with warm water thoroughly. Avoid sun exposure while using Clindoxyl Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking Clindoxyl Gel. You are recommended not to use Clindoxyl Gel for more than 12 weeks at once. Do not apply Clindoxyl Gel in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects such as redness, irritation, skin peeling, or discomfort. If you have intestine problems, ulcerative colitis (inflammation and sores in the digestive tract), or if you ever had severe diarrhoea caused by any antibiotic medicine, please inform your doctor before taking Clindoxyl Gel. 

Drug Interactions

Drug-Drug Interaction: Inform your doctor if you are taking vitamin A-related drugs known as retinoids (isotretinoin, bexarotene, adapalene, trifarotene), skeletal muscle relaxants (atracurium, cisatracurium, doxacurium, pancuronium, rocuronium, rapacuronium, vecuronium, pipecuronium, mivacurium, metocurine, tubocurarine, succinylcholine), antibiotics (dapsone).

Drug- Food Interaction: No interactions found.

Drug-Disease Interaction: If you have intestine problems, ulcerative colitis (inflammation and sores in the digestive tract), or if you ever had severe diarrhoea caused by any antibiotic medicine, please inform your doctor before taking Clindoxyl Gel. 

Drug-Drug Interactions Checker List

  • ISOTRETINOIN
  • BEXAROTENE
  • ADAPALENE
  • TRIFAROTENE
  • ATRACURIUM
  • CISATRACURIUM
  • DOXACURIUM
  • PANCURONIUM
  • ROCURONIUM
  • RAPACURONIUM
  • VECURONIUM
  • PIPECURONIUM
  • MIVACURIUM
  • METOCURINE
  • TUBOCURARINE
  • SUCCINYLCHOLINE
  • DAPSONE

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid sun exposure while using Clindoxyl Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
  • Regular exercise can improve your mood and self-esteem though it doesn’t clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.
  • Do regular hair wash regularly and avoid hair falling across the face.
  • Remove the make-up completely before going to bed.
  • Avoid using products that may cause skin irritation such as harsh soaps, skin cleansers, shampoos, hair removers or waxes, hair colouring or permanent chemicals, detergents, and rough fabrics.

Special Advise

  • Do not squeeze, pop or pick spots as it may worsen them and cause permanent scarring.
  • You are advised to consult a dermatologist if acne persists or worsens after using Clindoxyl Gel for 1 month.

Disease/Condition Glossary

Acne: It is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads, and blackheads. Acne affects people of all ages but is most common among teenagers. The symptoms of acne include pus-filled pimples, uninflamed (not swollen) blackheads, red, large, and tender bumps. The treatment for acne includes certain creams, cleansers, and antibiotics.

Consult Doctor

About Clindoxyl Gel

Clindoxyl Gel belongs to the class of dermatological preparations called ‘antiacne’ used to treat acne (pimples) and kill bacteria, causing acne. Acne is a common skin condition and occurs when hair follicles are blocked with dead skin cells and oil. The acne-causing bacteria feeds on sebum (natural oil produced by skin) causing redness and swelling.

Clindoxyl Gel is a combination of two drugs: Clindamycin (antibiotic) and Benzoyl peroxide (keratolytic agent). Clindamycin belongs to the class of antibiotics that inhibits the production of essential proteins that are necessary for bacteria to grow, multiply and increase in numbers. Thereby, stops or slows down the growth of bacteria and clears acne. Benzoyl peroxide is a keratolytic agent that breaks down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Thereby, helps in reducing blackheads and whiteheads. Additionally, Benzoyl peroxide possesses antibacterial properties and kills bacteria that cause acne, and reduces inflamed acne spots.

Use Clindoxyl Gel as prescribed. Clindoxyl Gel is only for external use. Avoid contact of Clindoxyl Gel with nose, ears, mouth, or eyes. In case Clindoxyl Gel comes in contact with these areas accidentally, rinse with warm water thoroughly. Your doctor will advise you how often you take Clindoxyl Gel based on your medical condition. In some cases, you may experience skin peeling, dry skin, pain, redness, itching, or burning sensation at the site of application. Most of these side effects of Clindoxyl Gel do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Clindoxyl Gel or any other medicines, please tell your doctor. Do not apply Clindoxyl Gel to cuts, open wounds, broken, sunburnt, or sensitive skin areas. Avoid sun exposure while using Clindoxyl Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking Clindoxyl Gel. Do not apply Clindoxyl Gel in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects such as redness, irritation, skin peeling, or discomfort. If you have intestine problems, ulcerative colitis (inflammation and sores in the digestive tract), or if you ever had severe diarrhoea caused by any antibiotic medicine, please inform your doctor before taking Clindoxyl Gel. 

Clindoxyl Gel 10 gm, Pack of 1 Gel
Non returnable*
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COD available

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Composition :

BENZOYL PEROXIDE-5%W/W + CLINDAMYCIN-1%W/W

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

Country of origin

India

Manufacturer/Marketer address

Dr. Annie Besant Road, Mumbai - 400 030
Other Info - CLI0217

FAQs

Clindoxyl Gel contains Clindamycin and Benzoyl peroxide. Clindamycin is an antibiotic that works by inhibiting the production of essential proteins that are necessary for bacteria to grow, multiply and increase in numbers. Thereby, stops or slows down the growth of bacteria and clears acne. Benzoyl peroxide is a keratolytic agent that works by breaking down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Thereby, helps in reducing blackheads and whiteheads. Additionally, Benzoyl peroxide possesses antibacterial properties and kills bacteria that causes acne and reduces inflamed acne spots.

Yes, Clindoxyl Gel may cause photosensitivity (increased skin sensitivity to sunlight) in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use a sunscreen and wear protective clothing while going out to prevent sunburn.

Yes, Clindoxyl Gel may cause skin irritation, redness or peeling in some people. However, if the irritation persists or worsens, stop using Clindoxyl Gel and consult a doctor.

Yes, Clindoxyl Gel may bleach coloured fabrics or hair. Therefore, avoid contact of Clindoxyl Gel with hair or fabrics and thoroughly wash your hands after using Clindoxyl Gel.

You are not recommended to use Clindoxyl Gel with dapsone (antibiotic) at the same time as it may cause temporary change in colour of facial hair (orange or yellow colour). However, please consult a doctor before using Clindoxyl Gel with any other medicines.

Yes, Clindoxyl Gel may cause dryness of the skin. You can use a fragrance-free, oil-free, hypoallergic moisturizer while using Clindoxyl Gel to prevent dry skin. However, do not apply Clindoxyl Gel and moisturizer at the same time as it may reduce the effectiveness of Clindoxyl Gel. Please consult a doctor before using other products with Clindoxyl Gel.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
icon image

Keep Refrigerated. Do not freeze.

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Alcohol

Caution

Interaction of Clindoxyl Gel with alcohol is unknown. Please consult a doctor before consuming alcohol while using Clindoxyl Gel.

bannner image

Pregnancy

Caution

Please consult a doctor if you are pregnant. Clindoxyl Gel is prescribed to pregnant women only if the doctor thinks benefits outweigh risks.

bannner image

Breast Feeding

Caution

It is unknown whether Clindoxyl Gel is excreted in human milk. Therefore, Clindoxyl Gel is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. However, do not apply Clindoxyl Gel on the chest area to avoid the contact of Clindoxyl Gel with the baby.

bannner image

Driving

Safe if prescribed

Clindoxyl Gel usually does not affect your ability to drive or operate machinery.

bannner image

Liver

Safe if prescribed

If you have any concerns regarding the use of Clindoxyl Gel in patients with Liver problems, please consult a doctor.

bannner image

Kidney

Safe if prescribed

If you have any concerns regarding the use of Clindoxyl Gel in patients with kidney problems, please consult a doctor.

bannner image

Children

Unsafe

Clindoxyl Gel is not recommended for children below 12 years of age, as the safety and effectiveness were not established.

Product Substitutes

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:33 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.3238.pdf
  2. https://www.drugs.com/mtm/benzoyl-peroxide-and-clindamycin-topical.html

Uses of Clindoxyl Gel

Acne (pimples)

Medicinal Benefits

Clindoxyl Gel is a combination of two drugs: Clindamycin and Benzoyl peroxide used to treat acne (pimples). Clindamycin is a broad-spectrum antibiotic that acts against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. The acne-causing bacteria feeds on sebum produced by sebaceous (oil) glands in the skin and produce fatty acids and waste products that irritate oil glands, causing redness and swelling. Clindamycin inhibits the production of essential proteins necessary for bacteria to grow, multiply and increase in numbers. Thereby, stops or slows down the growth of bacteria and clears acne. Benzoyl peroxide is a keratolytic agent that breaks down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Thereby, helps in reducing blackheads and whiteheads. Additionally, Benzoyl peroxide possesses antibacterial properties and kills bacteria that causes acne and reduces inflamed acne spots. 

Directions for Use

Wash your hands before and after applying Clindoxyl Gel. Before using it, wash the affected area with warm water. Apply a small amount of Clindoxyl Gel as a thin layer and gently rub on the clean and dry affected area of the skin in the evening. Clindoxyl Gel is only for external use. If you are using Clindoxyl Gel on face, avoid contact with eyes as it may cause irritation. In case Clindoxyl Gel comes in contact with eyes accidentally, rinse with water thoroughly. If you still have a problem with your eye or notice any vision problems, consult your doctor immediately.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are known to be allergic to Clindoxyl Gel or any other medicines, please tell your doctor. Do not apply Clindoxyl Gel to cuts, open wounds, broken, sunburnt, or sensitive skin areas. Do not swallow Clindoxyl Gel. In case of accidental swallowing, please consult a doctor. Avoid contact of Clindoxyl Gel with nose, ears, mouth, or eyes. In case Clindoxyl Gel comes in contact with these areas accidentally, rinse with warm water thoroughly. Avoid sun exposure while using Clindoxyl Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking Clindoxyl Gel. You are recommended not to use Clindoxyl Gel for more than 12 weeks at once. Do not apply Clindoxyl Gel in large amounts or use for a long time than prescribed as it does not give quick or better results but increases the risk of side effects such as redness, irritation, skin peeling, or discomfort. If you have intestine problems, ulcerative colitis (inflammation and sores in the digestive tract), or if you ever had severe diarrhoea caused by any antibiotic medicine, please inform your doctor before taking Clindoxyl Gel. 

Therapeutic Class

ANTIACNE

Drug-Drug Interactions

verifiedApollotooltip
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Drug Interactions Checker List

  • ISOTRETINOIN
  • BEXAROTENE
  • ADAPALENE
  • TRIFAROTENE
  • ATRACURIUM
  • CISATRACURIUM
  • DOXACURIUM
  • PANCURONIUM
  • ROCURONIUM
  • RAPACURONIUM
  • VECURONIUM
  • PIPECURONIUM
  • MIVACURIUM
  • METOCURINE
  • TUBOCURARINE
  • SUCCINYLCHOLINE
  • DAPSONE

Diet & Lifestyle Advise

  • Avoid sun exposure while using Clindoxyl Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
  • Regular exercise can improve your mood and self-esteem though it doesn’t clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.
  • Do regular hair wash regularly and avoid hair falling across the face.
  • Remove the make-up completely before going to bed.
  • Avoid using products that may cause skin irritation such as harsh soaps, skin cleansers, shampoos, hair removers or waxes, hair colouring or permanent chemicals, detergents, and rough fabrics.

Habit Forming

No

Special Advise

  • Do not squeeze, pop or pick spots as it may worsen them and cause permanent scarring.
  • You are advised to consult a dermatologist if acne persists or worsens after using Clindoxyl Gel for 1 month.

Disease/Condition Glossary

Acne: It is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads, and blackheads. Acne affects people of all ages but is most common among teenagers. The symptoms of acne include pus-filled pimples, uninflamed (not swollen) blackheads, red, large, and tender bumps. The treatment for acne includes certain creams, cleansers, and antibiotics.

Clindoxyl Gel Substitute

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