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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Whats That

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Manufacturer/Marketer

Carron Biotech

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About COLONA-PLUS TABLETS

COLONA-PLUS TABLETS belongs to a group of medications called ‘antianxiety medications' used in the treatment of anxiety disorders. Anxiety is a mental health disorder characterized by feelings of intense, excessive and persistent worry or fear that are strong enough to interfere with one’s daily activities. Symptoms of anxiety include rapid breathing, increased heart rate, restlessness, trouble concentrating, and difficulty falling asleep.

COLONA-PLUS TABLETS is a combination of two drugs: clonazepam and escitalopram oxalate. Clonazepam produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram oxalate increases the serotonin hormone levels that improve mood, behaviour, and cognition in patients with anxiety.

Take COLONA-PLUS TABLETS as prescribed by the doctor. Sometimes, COLONA-PLUS TABLETS may cause common side effects such as nausea, headache, dizziness, confusion, drowsiness, fatigue, sleeping problems, breathlessness, poor coordination of movements, stomach upset, decreased libido (low sexual desire), and memory problems. Consult your doctor if any of these side effects persist or worsen.

Do not take COLONA-PLUS TABLETS if you are allergic to any of its components. Inform your doctor if you have seizures, liver problems, sleep disorders, lung problems, and alcohol or drug abuse. Do not consume alcohol as it can increase the risk of side effects. Consult your doctor if you are pregnant or breastfeeding before taking this medicine. COLONA-PLUS TABLETS may cause dizziness and drowsiness, so avoid driving vehicles or operating machinery unless you are alert.

Uses of COLONA-PLUS TABLETS

Anxiety disorder

Directions for Use

Take COLONA-PLUS TABLETS as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

COLONA-PLUS TABLETS is a combination of two medicines: clonazepam and escitalopram oxalate. It is used to treat anxiety disorders. Clonazepam increases the effect of gamma-aminobutyric acid (GABA) and produces a calming effect by suppressing the abnormal activity of nerve cells. Escitalopram oxalate is a selective serotonin reuptake inhibitor (SSRI); it increases the serotonin levels in the brain, thereby improving mood and behaviour.

Storage

Store in a cool and dry place away from sunlight

Side Effects of COLONA-PLUS TABLETS

  • Nausea
  • Vomiting
  • Diarrhoea
  • Dizziness
  • Confusion
  • Uncoordinated body movements
  • Drowsiness
  • Fatigue
  • Delayed ejaculation
  • Decreased libido (low sexual desire)
  • Memory problems

Drug Warnings

Do not take COLONA-PLUS TABLETS if you are allergic to any of the ingredients. Tell your doctor if you are taking antidepressants, antipsychotic medication, antihypertensives, or antibiotics. Talk to your doctor if you have a history of seizures, bipolar disorder, or schizophrenia. Patients with liver diseases, diabetes, heart disease, and bleeding disorders should use COLONA-PLUS TABLETS with caution. Please do not stop taking COLONA-PLUS TABLETS abruptly as it can cause withdrawal symptoms. COLONA-PLUS TABLETS may cause suicidal thoughts and worsen anxiety.

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
ClonazepamMethadone
Severe

Drug-Drug Interactions

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ClonazepamSodium oxybate
Critical
How does the drug interact with Colona-plus Tablets:
Taking Colona-plus Tablets with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Colona-plus Tablets and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamMethadone
Severe
How does the drug interact with Colona-plus Tablets:
Co-administration of Colona-plus Tablets with methadone may cause serious side effects like respiratory depression (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Consult the doctor if you are taking Colona-plus Tablets with methadone. Until you know how these medicines affect you, avoid driving or operating hazardous machinery as these medications may cause dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not discontinue the medication without a doctor's advice.
ClonazepamAlfentanil
Severe
How does the drug interact with Colona-plus Tablets:
Co-administration of Alfentanil with Colona-plus Tablets can increase the risk of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Colona-plus Tablets and Alfentanil, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamButorphanol
Severe
How does the drug interact with Colona-plus Tablets:
Co-administration of Butorphanol with Colona-plus Tablets can increase the risk of side effects.

How to manage the interaction:
Although taking Colona-plus Tablets and Butorphanol together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you notice any symptoms like feeling dizzy, having trouble breathing, or feeling very tired, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamTramadol
Severe
How does the drug interact with Colona-plus Tablets:
Co-administration of Colona-plus Tablets with Tramadol may significantly lead to adverse effects such as respiratory difficulties (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Colona-plus Tablets and Tramadol together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as dizziness, drowsiness, difficulty concentrating, numbness and tingling of extremities, or hypersensitivity to light and noise, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClonazepamCodeine
Severe
How does the drug interact with Colona-plus Tablets:
Co-administration of Colona-plus Tablets with Codeine may cause serious side effects like respiratory depression.

How to manage the interaction:
Consult a doctor if you are taking Colona-plus Tablets with Codeine. Until you know how the medicines affect you, avoid driving or operating hazardous machinery as these medications may cause drowsiness, dizziness, difficulty concentrating, and impairment in judgment, reaction speed, and motor coordination. Do not exceed the dose and duration prescribed by your doctor. Do not stop using any medications without talking to a doctor.
ClonazepamMorphine
Severe
How does the drug interact with Colona-plus Tablets:
Using Morphine together with Colona-plus Tablets can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Morphine with Colona-plus Tablets can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like shortness of breath, feeling tired, having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.
ClonazepamTapentadol
Severe
How does the drug interact with Colona-plus Tablets:
Co-administration of Tapentadol together with Colona-plus Tablets can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Colona-plus Tablets with Tapentadol can result in an interaction, it can be taken if your doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
ClonazepamKetamine
Severe
How does the drug interact with Colona-plus Tablets:
When Colona-plus Tablets and Ketamine are taken together, may increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Ketamine and Colona-plus Tablets, but it can be taken if prescribed by a doctor. If you start feeling dizzy, tired, confused, have trouble focusing, feel very sleepy, or have trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
ClonazepamSufentanil
Severe
How does the drug interact with Colona-plus Tablets:
Co-administration of Sufentanil with Colona-plus Tablets can increase the risk of side effects.

How to manage the interaction:
Taking Colona-plus Tablets with Sufentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - feeling tired or sleepy, having trouble breathing, or a slower heartbeat - make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Attend therapy sessions regularly.
  • Eat a healthy diet.
  • Try to stay active and exercise regularly.
  • Take ample rest. Get enough sleep.
  • Meditate regularly as it helps in easing anxiety.
  • Avoid smoking, caffeine, and alcohol consumption.
  • Foods and drinks like salmon, chamomile, turmeric, dark chocolate, green tea, and yoghurt may help with anxiety.

Habit Forming

Yes

Therapeutic Class

ANXIOLYTICS

COLONA-PLUS TABLETS Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SELEGILINE
  • MOCLOBEMIDE
  • CIMETIDINE
  • LINEZOLID
  • RIFAMPICIN

Special Advise

  • Your doctor may advise regular eye checkups as using COLONA-PLUS TABLETS may worsen the symptoms in patients with open-angle glaucoma.
  • Consult your doctor immediately if there is any change in behaviour or if you have any suicidal thoughts.

Disease/Condition Glossary

Anxiety: It is a feeling of fear, worry or uneasiness. It is usually a normal emotion. However, if a person experiences repeated episodes of anxiety that worsen over time or interfere with daily activities, the condition is called anxiety disorder. Symptoms include irritability, lack of concentration, nervousness, fatigue, rapid heartbeat and trembling.

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