CREON 10000I.U CAPSULE

CREON 10000I.U CAPSULE is a pancreatic enzyme supplement indicated for the treatment of exocrine pancreatic insufficiency (pancreatin enzyme deficiency) due to cystic fibrosis (an inherited disorder that damages the lungs and digestive system), chronic pancreatitis (inflammation of the pancreas), or other conditions. Exocrine pancreatic insufficiency occurs in people whose bodies do not make enough of their own enzymes.

CREON 10000I.U CAPSULE contains Pancreatin, which is a combination of digestive enzymes such as porcine-derived lipases, proteases, and amylases. These enzymes help in the digestion of food. CREON 10000I.U CAPSULE mixes thoroughly with the food and helps in digestion as it passes through the gut.

You are advised to take CREON 10000I.U CAPSULE for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, CREON 10000I.U CAPSULE may cause certain common side-effects such as nausea, mild stomach pain, diarrhoea, and mild skin rash. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking CREON 10000I.U CAPSULE if you have gout, asthma, or any disease condition. Consult your doctor before taking CREON 10000I.U CAPSULE if you are pregnant or breastfeeding. CREON 10000I.U CAPSULE may cause dizziness, so drive with caution. It is unknown whether alcohol interacts with CREON 10000I.U CAPSULE; please consult your doctor if you have any concerns regarding this. CREON 10000I.U CAPSULE can be given to children if prescribed by the doctor; the dose depends upon the child’s age and body weight.

CREON 10000I.U CAPSULE is a pancreatic enzyme supplement indicated for the treatment of exocrine pancreatic insufficiency (pancreatin enzyme deficiency) due to cystic fibrosis (an inherited disorder that damages the lungs and digestive system), chronic pancreatitis (inflammation of the pancreas), or other conditions. Pancreatin is a combination of digestive enzymes such as porcine-derived lipases, proteases, and amylases. These enzymes help in the digestion of food. CREON 10000I.U CAPSULE mixes thoroughly with the food and helps in digestion as it passes through the gut. CREON 10000I.U CAPSULE may also be used to treat steatorrhea (oily, smelly stools due to lack of fat absorption). 

• Nausea
• Mild stomach pain 
• Diarrhoea
• Mild skin rash

Do not take CREON 10000I.U CAPSULE if you are allergic to pork (pig), cow or buffalo products. Consult your doctor if you experience stomach pain, swelling, constipation, and vomiting as patients taking CREON 10000I.U CAPSULE with cystic fibrosis may develop a rare bowel condition called fibrosing colonopathy. Inform your doctor before taking CREON 10000I.U CAPSULE if you have gout, asthma, or any disease condition. Consult your doctor before taking CREON 10000I.U CAPSULE if you are pregnant or breastfeeding. CREON 10000I.U CAPSULE may cause dizziness, so drive with caution. It is unknown whether alcohol interacts with CREON 10000I.U CAPSULE; please consult your doctor if you have any concerns regarding this. CREON 10000I.U CAPSULE can be given to children if prescribed by the doctor; the dose depends upon the child’s age and body weight.

Drug-Drug Interactions: CREON 10000I.U CAPSULE may interact with calcium, iron, and calcium supplements. 

Drug-Food Interactions: No interaction found/established. 

Drug-Disease Interactions: No interaction found/established. 

• CALCIUM
• CALCITRIOL
• FERROUS SULPHATE
• IRON

• Eat small portions of meals 3-5 times a day as larger meals make the digestive system work overtime.
• Include diet rich in fruits and vegetables.
• Avoid processed, deep-fried foods as they are hard to digest.
• Maintain a balanced diet which includes proteins, carbohydrates, and fats. 
• Stay hydrated by drinking enough water as it helps the digestive system to function smoothly.
• Avoid highly processed foods which contain trans-fat, hydrogenated fats, and saturated fats. Instead of include foods containing monounsaturated, polyunsaturated and omega-3 fatty acids. Include olive oil, peanut oil, seeds, nuts, salmon, and tuna fish as they contain healthy fats
• Avoid foods rich in fibre such as brown rice, barley, lentils, and peas as they might interfere with the enzyme activity.
• Avoid or limit alcohol consumption as it can cause increased damage to the pancreas.

• Try to avoid taking an antacid within 1 hour before or after you take CREON 10000I.U CAPSULE. Simultaneous use of antacids containing calcium carbonate and/or magnesium hydroxide may lead to pancreatin deficiency. 

Exocrine pancreatic insufficiency: Pancreas play an important role in the digestion of food. It produces enzymes which help in the breakdown of food and absorption of nutrients. Exocrine pancreatic insufficiency occurs in people whose bodies do not make enough of their own enzymes. This leads to the inability of proper food digestion due to the pancreas' lack of a digestive enzyme. Exocrine pancreatic insufficiency could occur due to various conditions such as cystic fibrosis (an inherited disorder that damages the lungs and digestive system), pancreatitis (inflammation of the pancreas), diabetes, celiac disease (inability to digest gluten), pancreatic cancer, inflammatory bowel disease, Zollinger-Ellison disease, pancreatic or stomach surgery. Exocrine pancreatic insufficiency symptoms include abdominal pain, bloating, diarrhoea, flatulence, weight loss, and steatorrhea (loose, fatty, smelly stools).