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  1. Home
  2. OTC

  3. Crocin Advance Tablet 20's

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About Crocin Advance Tablet

Crocin Advance Tablet Test Testing Gopal belongs to the group of medicines called analgesics (pain killers), and antipyretics (fever-reducing agents) used to reduce fever and treat mild to moderate pain. Also, it is used to relieve headache, migraine, toothache, period pain, back pain, muscle pain and rheumatic pains. Pain and fever are caused by the activation of pain receptors due to the release of certain natural chemicals in the body like prostaglandin. 

Crocin Advance Tablet works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins. Thus, reduces pain. Also, Crocin Advance Tablet affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thereby, it reduces fever.

Take Crocin Advance Tablet as advised by your physician. Your doctor will recommend how often you need to take Crocin Advance Tablet based on your medical condition. In some cases, Crocin Advance Tablet may cause side effects such as nausea, stomach pain and dark coloured urine. Most of these side effects of Crocin Advance Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

Avoid taking Crocin Advance Tablet if allergic to it. Crocin Advance Tablet is not recommended for children below 6 years of age. If you are pregnant or breastfeeding, please consult a physician before using Crocin Advance Tablet . Avoid alcohol consumption with Crocin Advance Tablet as it may increase the risk of liver damage. If you have an impaired nutritional state caused by anorexia (eating disorder), malnutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking Crocin Advance Tablet .a

Uses of Crocin Advance Tablet

fever

Medicinal Benefits

Crocin Advance Tablet contains Paracetamol, an analgesic (pain killer) and antipyretic (reduces fever). It inhibits the production of certain chemical messengers in the brain known as prostaglandins. Thus, reduces pain. Also, Crocin Advance Tablet affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thereby, it reduces fever.

Directions for Use

Tablet/capsule: Swallow it as a whole with a glass of water. It can be taken with or without food anytime. Do not crush, break or chew it. Oral liquid: Shake the bottle well before use. Take the suggested dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Crocin Advance Tablet

side effect 1

Drug Warnings

Avoid taking Crocin Advance Tablet if allergic to it. Crocin Advance Tablet is not recommended for children below 6 years of age. If you are pregnant or breastfeeding, please consult a physician before using Crocin Advance Tablet . Avoid alcohol consumption with Crocin Advance Tablet as it may increase the risk of liver damage. If you have an impaired nutritional state caused by anorexia (eating disorder), wrong nutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking Crocin Advance Tablet . Avoid taking more than recommended doses as it may increase the risk of serious liver damage.

Drug Interactions

Drug-Drug Interactions: Crocin Advance Tablet may interact with blood thinners (warfarin), cholesterol-lowering drugs (cholestyramine), analgesics (aspirin), antibiotics (chloramphenicol, rifampicin), anti-gout medicines (probenecid), antitubercular drug (isoniazid), anticonvulsants (lamotrigine, carbamazepine, phenytoin), and anti-nausea agents (metoclopramide, domperidone). 

Drug-Food Interactions: Crocin Advance Tablet may interact with St. John’s wort (herbal medicine to treat depression).  Avoid foods rich in carbohydrates, and pectin including jellies, cabbage, Brussels sprouts and broccoli as Crocin Advance Tablet may interact with these foods. Also, avoid intake of alcohol with Crocin Advance Tablet as it may increase the risk of liver damage.

Drug-Disease Interactions: If you have kidney or liver disease, hepatitis, Gilbert's syndrome (a liver condition), hemolytic anaemia (abnormal breakdown of red blood cells), G-6-PD deficiency (a hereditary condition resulting in low red blood cell counts), blood poisoning, inform your physician before taking Crocin Advance Tablet .

Drug-Drug Interactions Checker List

  • WARFARIN
  • CHOLESTYRAMINE
  • ASPIRIN
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHLORAMPHENICOL
  • RIFAMPICIN
  • PROBENECID
  • ISONIAZID
  • LAMOTRIGINE
  • CARBAMAZEPINE
  • PHENYTOIN

Habit Forming

No

Diet & Lifestyle Advise

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids such as soy, berries, broccoli, grapes and green tea help in reducing inflammation. 

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Avoid smoking and alcohol consumption.

Special Advise

If you have a high fever or signs of infection after using Crocin Advance Tablet for more than 3 days or if pain persists after using Crocin Advance Tablet for more than 5 days, please consult a physician.

Disease/Condition Glossary

Pain: It is a term used to describe any unpleasant feeling or discomfort. It occurs due to nerve damage (in cases of backache, toothache, or muscle pain) or persistent stimulation (in headaches or migraine). Pain may vary from mild to severe, depending on the underlying condition.

Fever: It is an abnormal increase in body temperature due to infection, chemotherapy, or various disease condition. If the body temperature is 98.6°F, it is normal and if it goes above 100.4°F (38℃), it is called fever or pyrexia. Body temperature is increased in response to infection or varied problems to protect the body. Flu is one of the most common causes of fever. 

Consult Doctor

About Crocin Advance Tablet

Crocin Advance Tablet Test Testing Gopal belongs to the group of medicines called analgesics (pain killers), and antipyretics (fever-reducing agents) used to reduce fever and treat mild to moderate pain. Also, it is used to relieve headache, migraine, toothache, period pain, back pain, muscle pain and rheumatic pains. Pain and fever are caused by the activation of pain receptors due to the release of certain natural chemicals in the body like prostaglandin. 

Crocin Advance Tablet works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins. Thus, reduces pain. Also, Crocin Advance Tablet affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thereby, it reduces fever.

Take Crocin Advance Tablet as advised by your physician. Your doctor will recommend how often you need to take Crocin Advance Tablet based on your medical condition. In some cases, Crocin Advance Tablet may cause side effects such as nausea, stomach pain and dark coloured urine. Most of these side effects of Crocin Advance Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

Avoid taking Crocin Advance Tablet if allergic to it. Crocin Advance Tablet is not recommended for children below 6 years of age. If you are pregnant or breastfeeding, please consult a physician before using Crocin Advance Tablet . Avoid alcohol consumption with Crocin Advance Tablet as it may increase the risk of liver damage. If you have an impaired nutritional state caused by anorexia (eating disorder), malnutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking Crocin Advance Tablet .a

Crocin Advance Tablet 20's, Pack of 20 TABLETS
Crocin Advance Tablet 20's, Pack of 20 TABLETS
Crocin Advance Tablet 20's, Pack of 20 TABLETS
Non returnable*
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Composition :

PARACETAMOL-500MG

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Country of origin

India

Manufacturer/Marketer address

24-25 Floor, One Horizon Center Golf Course Road, DLF Phase 5 Gurgaon 122002, India
Other Info - CRO0091

FAQs

Crocin Advance Tablet works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins. Thus, reducing pain. Also, Crocin Advance Tablet affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thus, it reduces fever.

You are not recommended to take Crocin Advance Tablet with warfarin as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you are supposed to use these medicines together, you are advised to contact your physician so that the dose may be adjusted appropriately to use safely.

Crocin Advance Tablet may affect how certain tests work such as blood sugar test and uric acid test. Therefore, if you are about to undergo blood test or any laboratory tests, inform your physician or lab technician that you are taking Crocin Advance Tablet .

You are not recommended to take Crocin Advance Tablet with other paracetamol containing products as it may cause paracetamol overdose.

If you take more than suggested doses of Crocin Advance Tablet , it may cause overdose and lead to serious liver damage. The symptoms of overdose include vomiting, loss of appetite, stomach pain, paleness and nausea. However, if you notice any of these symptoms while taking Crocin Advance Tablet , please consult a doctor immediately.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

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Alcohol

Safe

You are recommended to avoid consumption of alcohol with Paracetamol as it may cause severe liver damage.

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Pregnancy

Safe

Please consult a physician if you are pregnant or planning for pregnancy before using this medicine. Your physician may suggest the lowest dose of Paracetamol for the shortest duration if you are pregnant.

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Breast Feeding

Safe

Paracetamol may be excreted in small amounts in breast milk. Therefore, please consult a physician before using this medicine if you are breastfeeding.

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Driving

Safe

Crocin Advance Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Safe

Take Crocin Advance Tablet with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your physician as required.

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Kidney

Safe

Take Crocin Advance Tablet with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your physician as required.

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Children

Safe

Please consult a doctor. Your doctor will prescribe a suitable dose of Paracetamol based on the age, bodyweight and condition of your child.

Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:31 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.hpra.ie/img/uploaded/swedocuments/2b04cfdb-8571-4543-a4c9-b1380e0a92c3.pdf
  2. https://www.sahpra.org.za/wp-content/uploads/2020/06/Von-Paracetamol_PIL_Drugcompany_MCC-Format25-June-2001.pdf
  3. https://www.boots.com/wcsstore/ExtendedSitesCatalogAssetStore/Attachment/Product_PatientLeaflets/10186783%20Paracetamol%20PIL%2019%2009%202018.pdf
  4. https://www.drugs.com/paracetamol.html
  5. https://www.mims.com/india/drug/info/paracetamol?type=full&mtype=generic

Uses of Crocin Advance Tablet

fever

Medicinal Benefits

Crocin Advance Tablet contains Paracetamol, an analgesic (pain killer) and antipyretic (reduces fever). It inhibits the production of certain chemical messengers in the brain known as prostaglandins. Thus, reduces pain. Also, Crocin Advance Tablet affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thereby, it reduces fever.

Side effects of Crocin Advance Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Directions for Use

Tablet/capsule: Swallow it as a whole with a glass of water. It can be taken with or without food anytime. Do not crush, break or chew it. Oral liquid: Shake the bottle well before use. Take the suggested dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Avoid taking Crocin Advance Tablet if allergic to it. Crocin Advance Tablet is not recommended for children below 6 years of age. If you are pregnant or breastfeeding, please consult a physician before using Crocin Advance Tablet . Avoid alcohol consumption with Crocin Advance Tablet as it may increase the risk of liver damage. If you have an impaired nutritional state caused by anorexia (eating disorder), wrong nutrition or alcohol abuse or if you are dehydrated, inform your doctor before taking Crocin Advance Tablet . Avoid taking more than recommended doses as it may increase the risk of serious liver damage.

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Drug-Drug Interactions

verifiedApollotooltip
ParacetamolValdecoxib
Severe
ParacetamolKetoconazole
Severe

Drug-Drug Interactions

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ParacetamolValdecoxib
Severe
How does the drug interact with Crocin Advance Tablet:
Co-administration of Crocin Advance Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Crocin Advance Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Crocin Advance Tablet:
Co-administration of Crocin Advance Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Crocin Advance Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with Crocin Advance Tablet:
Co-administration of Crocin Advance Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Crocin Advance Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with Crocin Advance Tablet:
Co-administration of Teriflunomide with Crocin Advance Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Crocin Advance Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Crocin Advance Tablet:
Co-administration of ketamine and Crocin Advance Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Crocin Advance Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolOxazepam
Severe
How does the drug interact with Crocin Advance Tablet:
Co-administration of Crocin Advance Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Crocin Advance Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolLomitapide
Severe
How does the drug interact with Crocin Advance Tablet:
Co-administration of Lomitapide and Crocin Advance Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Crocin Advance Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Crocin Advance Tablet:
Co-administration of Mipomersen with Crocin Advance Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Crocin Advance Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Drug Interactions Checker List

  • WARFARIN
  • CHOLESTYRAMINE
  • ASPIRIN
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHLORAMPHENICOL
  • RIFAMPICIN
  • PROBENECID
  • ISONIAZID
  • LAMOTRIGINE
  • CARBAMAZEPINE
  • PHENYTOIN

Diet & Lifestyle Advise

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids such as soy, berries, broccoli, grapes and green tea help in reducing inflammation. 

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Avoid smoking and alcohol consumption.

Habit Forming

No

How Crocin Advance Tablet Works

how it works data here

What if I have taken an overdose of Crocin Advance Tablet

overdose test data here

Special Advise

If you have a high fever or signs of infection after using Crocin Advance Tablet for more than 3 days or if pain persists after using Crocin Advance Tablet for more than 5 days, please consult a physician.

Disease/Condition Glossary

Pain: It is a term used to describe any unpleasant feeling or discomfort. It occurs due to nerve damage (in cases of backache, toothache, or muscle pain) or persistent stimulation (in headaches or migraine). Pain may vary from mild to severe, depending on the underlying condition.

Fever: It is an abnormal increase in body temperature due to infection, chemotherapy, or various disease condition. If the body temperature is 98.6°F, it is normal and if it goes above 100.4°F (38℃), it is called fever or pyrexia. Body temperature is increased in response to infection or varied problems to protect the body. Flu is one of the most common causes of fever. 

Crocin Advance Tablet Substitute

Substitutes safety advice

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