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  3. DIACOBAL 500MCG TABLET

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About DIACOBAL 500MCG TABLET

DIACOBAL 500MCG TABLET belongs to the class of 'vitamins', primarily used to treat vitamin b12 deficiency and peripheral neuropathy (nerve damage in the hands and feet). It is also used to prevent/treat megaloblastic anaemia (anaemia with unusually large red blood cells). Vitamin B12 deficiency occurs when the body has lower levels of vitamin B12 than normal. Symptoms include fatigue, breathlessness, numbness, poor balance, and memory trouble.

DIACOBAL 500MCG TABLET contains Methylcobalamin, a form of vitamin B12 that regulates body functions, such as cell multiplication, blood formation, and protein synthesis. It also helps restore nucleic acid in the nerve cells.

Your doctor will decide the dosage based on your medical condition. Sometimes, DIACOBAL 500MCG TABLET may cause common side effects like nausea, vomiting, diarrhoea, loss of appetite, and headache. These side effects do not require medical attention and gradually resolve over time. If these side effects are persistent, please reach out to your doctor.

Let your doctor know if you use any otrher medications, including other vitamins, before starting DIACOBAL 500MCG TABLET. Please tell your doctor if you are allergic to any of the components in DIACOBAL 500MCG TABLET. It is essential to let your doctor know if you are pregnant, planning to conceive or are a breastfeeding mother. Avoid consuming alcohol along with DIACOBAL 500MCG TABLET to ensure maximum absorption of nutrients. DIACOBAL 500MCG TABLET should be used in children only with the doctor's advice.

Uses of DIACOBAL 500MCG TABLET

Vitamin B12 deficiency and peripheral neuropathy.

Medicinal Benefits

DIACOBAL 500MCG TABLET contains Methylcobalamin, a form of Vitamin B12, which regulates body functions and helps rejuvenate and protect damaged nerve cells by producing a substance called myelin. It prevents nerve damage in peripheral neuropathy and treats symptoms of vitamin B12 deficiency. It promotes amino acid synthesis and plays an important role in protein formation. DIACOBAL 500MCG TABLET also treats and prevents megaloblastic anemia, a vitamin deficiency anemia caused by low vitamin b12 levels.

Directions for Use

Tablet/capsule: Swallow tablet/capsule as a whole with a glass of water. You can take it with or without food at regular intervals, as recommended by the doctor. Do not crush, chew or break it. Liquid: Measure the liquid form with a measuring cup or dosing syringe and take it as advised by the doctor.Oral drops: Shake the bottle well before use. Take the suggested dose by mouth using the dropper provided by the pack.Disintegrating strip: Place the strip on the top of your tongue and allow it to disintegrate. Swallow the dissolved medicine. Do not swallow as a whole or chew the strip. Avoid handling the strip with wet hands. Disintegrating tablet: Check the label for directions before use. Disperse the tablet in the recommended amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Granules: Check the label for directions before use. Take it as advised by your doctor.Oral Lozenges: Place the lozenge in your mouth between your gums and cheek until it is dissolved. Do not chew or swallow it as a whole.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DIACOBAL 500MCG TABLET

  • Nausea
  • Vomiting
  • Headache
  • Loss of appetite
  • Diarrhoea

Drug Warnings

Let your doctor know if you have any heart, liver or kidney diseases before starting DIACOBAL 500MCG TABLET. DIACOBAL 500MCG TABLET should be used during pregnancy only when advised by the doctor. DIACOBAL 500MCG TABLET is excreted into breast milk. Hence, breastfeeding women should consult their doctor before taking DIACOBAL 500MCG TABLET. Drinking alcohol may hinder vitamin absorption; therefore, it is advised to limit the alcohol intake while using DIACOBAL 500MCG TABLET. DIACOBAL 500MCG TABLET is safe for children only when recommended by the doctor.

Drug Interactions

Drug-Drug Interaction: DIACOBAL 500MCG TABLET may interact with antibiotics (neomycin, chloramphenicol), antituberculosis antibiotics (aminosalicylic acid), heartburn medication (omeprazole, cimetidine), and gout medicines (colchicine).

Drug-Food Interaction: No interactions were found.

Drug-Disease Interaction: Inform your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food), liver, kidney or heart diseases, optic nerve damage, iron/folic acid deficiency, low potassium levels, and allergic reactions before starting DIACOBAL 500MCG TABLET.

Drug-Drug Interactions Checker List

  • NEOMYCIN
  • CHLORAMPHENICOL
  • AMINOSALICYLIC ACID
  • OMEPRAZOLE
  • CIMETIDINE
  • COLCHICINE

Habit Forming

No

Diet & Lifestyle Advise

  • Try Vitamin B complex food sources like milk, cheese, eggs, liver and kidney, chicken, red meat, tuna, mackerel, salmon, shellfish, oysters, clams, dark green vegetables such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.
  • Taking vegetables like acorn squash, asparagus, beet greens, Brussels sprouts, and spinach can help cope with Vitamin B deficiency.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Avoid smoking and alcohol consumption.
  • Exercise regularly and maintain a healthy lifestyle. Avoid excess fatty foods.

Special Advise

 

Disease/Condition Glossary

Vitamin B12 deficiency (cobalamin deficiency): Vitamin B12 deficiency occurs when the body has lower levels of vitamin B12 than normal. Symptoms include fatigue, breathlessness, numbness, poor balance and memory trouble. Pernicious anaemia, an autoimmune disease, is the most common cause of B12 deficiency. In this condition, the body cannot absorb enough vitamin B12 since the body's immune system produces antibodies against the intrinsic factor (a protein that helps the body absorb vitamin B12). Other causes include stomach or gut issues, where the body cannot absorb the vitamin, medications like antidiabetics and stomach-related drugs, and dietary restrictions like being a strict vegan.

Peripheral neuropathy/peripheral neuritis: It is defined as damage to nerves outside the brain and spinal cord. The pain could be intermittent or continuous, with a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Symptoms include spontaneous, un-triggered pain, unpleasant feeling, shooting, burning or stabbing pain, muscle weakness, and cramping.

Consult Doctor

About DIACOBAL 500MCG TABLET

DIACOBAL 500MCG TABLET belongs to the class of 'vitamins', primarily used to treat vitamin b12 deficiency and peripheral neuropathy (nerve damage in the hands and feet). It is also used to prevent/treat megaloblastic anaemia (anaemia with unusually large red blood cells). Vitamin B12 deficiency occurs when the body has lower levels of vitamin B12 than normal. Symptoms include fatigue, breathlessness, numbness, poor balance, and memory trouble.

DIACOBAL 500MCG TABLET contains Methylcobalamin, a form of vitamin B12 that regulates body functions, such as cell multiplication, blood formation, and protein synthesis. It also helps restore nucleic acid in the nerve cells.

Your doctor will decide the dosage based on your medical condition. Sometimes, DIACOBAL 500MCG TABLET may cause common side effects like nausea, vomiting, diarrhoea, loss of appetite, and headache. These side effects do not require medical attention and gradually resolve over time. If these side effects are persistent, please reach out to your doctor.

Let your doctor know if you use any otrher medications, including other vitamins, before starting DIACOBAL 500MCG TABLET. Please tell your doctor if you are allergic to any of the components in DIACOBAL 500MCG TABLET. It is essential to let your doctor know if you are pregnant, planning to conceive or are a breastfeeding mother. Avoid consuming alcohol along with DIACOBAL 500MCG TABLET to ensure maximum absorption of nutrients. DIACOBAL 500MCG TABLET should be used in children only with the doctor's advice.

DIACOBAL 500MCG TABLET, Pack of 10 TABLETS
Non returnable*
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Synonym :

MECOBALAMIN

Composition :

METHYLCOBALAMIN-500MCG

Manufacturer/Marketer :

Mano Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Country of origin

India

Manufacturer/Marketer address

no. 447, poonamallee high road, aminjikarai, chennai 600029.
Other Info - DIA0078

FAQs

DIACOBAL 500MCG TABLET treats B12 deficiency by restoring low levels of vitamin B12 in the body. It has extended benefits in treating peripheral neuropathic pain by preventing nerve cell damage. It is further involved in cell multiplication, blood formation, and protein synthesis.

Please continue using DIACOBAL 500MCG TABLET for as long as the doctor has advised it for you based on your medical condition. It may take several months to cure a vitamin deficiency; hence do not abruptly stop taking this supplement. However, if you did not notice any improvement in your condition, it is advised to consult a doctor.

Long-term usage of DIACOBAL 500MCG TABLET is not recommended in people whose occupation involves mercury handling and exposure. Please check with your doctor for more information.

Taking Metformin (an anti-diabetic drug) for longer durations is associated with the risk of vitamin B12 deficiency. Please consult your doctor if you have any concerns; your doctor may advise vitamin B12 supplements if needed.

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid consuming alcohol with DIACOBAL 500MCG TABLET to ensure maximum absorption of nutrients.

bannner image

Pregnancy

Caution

DIACOBAL 500MCG TABLET should be used during pregnancy only when advised by your doctor. Let your doctor know if you are pregnant or planning to conceive before starting DIACOBAL 500MCG TABLET.

bannner image

Breast Feeding

Caution

DIACOBAL 500MCG TABLET may be excreted into breast milk. Please consult your doctor before taking the supplement if you are a breastfeeding mother.

bannner image

Driving

Not applicable

DIACOBAL 500MCG TABLET usually does not interfere with your driving ability

bannner image

Liver

Caution

Let your doctor know if you have any history of liver diseases before taking DIACOBAL 500MCG TABLET. Your dosage may be adjusted in case of liver impairment.

bannner image

Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking DIACOBAL 500MCG TABLET. Your dosage may be adjusted in case of renal impairment.

bannner image

Children

Caution

DIACOBAL 500MCG TABLET should be used in children only when the doctor advises. The doctor will recommend the dosage of DIACOBAL 500MCG TABLET based on the child's age and weight.

Product Substitutes

Author Details

Doctor image

Written By

Divya L

PharmaD

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 8, 2025 | 9:45 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://medex.com.bd/attachments/hjEtbFDa968hT1pWc00nDv84EcCfzU/
  2. https://quest3plus.bpfk.gov.my/front-end/attachment/4391/pharma/234423/V_3942_20170323_021905_D4.pdf
  3. https://www1.ndmctsgh.edu.tw/pharm/Home/GetInsertEFile?id=005MET29
  4. https://www.drugs.com/mtm/methylcobalamin-vitamin-b12.html
  5. https://www.fda.gov/media/150007/download
  6. https://www.webmd.com/vitamins/ai/ingredientmono-926/vitamin-b12

Uses of DIACOBAL 500MCG TABLET

Vitamin B12 deficiency and peripheral neuropathy.

Medicinal Benefits

DIACOBAL 500MCG TABLET contains Methylcobalamin, a form of Vitamin B12, which regulates body functions and helps rejuvenate and protect damaged nerve cells by producing a substance called myelin. It prevents nerve damage in peripheral neuropathy and treats symptoms of vitamin B12 deficiency. It promotes amino acid synthesis and plays an important role in protein formation. DIACOBAL 500MCG TABLET also treats and prevents megaloblastic anemia, a vitamin deficiency anemia caused by low vitamin b12 levels.

Directions for Use

Tablet/capsule: Swallow tablet/capsule as a whole with a glass of water. You can take it with or without food at regular intervals, as recommended by the doctor. Do not crush, chew or break it. Liquid: Measure the liquid form with a measuring cup or dosing syringe and take it as advised by the doctor.Oral drops: Shake the bottle well before use. Take the suggested dose by mouth using the dropper provided by the pack.Disintegrating strip: Place the strip on the top of your tongue and allow it to disintegrate. Swallow the dissolved medicine. Do not swallow as a whole or chew the strip. Avoid handling the strip with wet hands. Disintegrating tablet: Check the label for directions before use. Disperse the tablet in the recommended amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Granules: Check the label for directions before use. Take it as advised by your doctor.Oral Lozenges: Place the lozenge in your mouth between your gums and cheek until it is dissolved. Do not chew or swallow it as a whole.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Let your doctor know if you have any heart, liver or kidney diseases before starting DIACOBAL 500MCG TABLET. DIACOBAL 500MCG TABLET should be used during pregnancy only when advised by the doctor. DIACOBAL 500MCG TABLET is excreted into breast milk. Hence, breastfeeding women should consult their doctor before taking DIACOBAL 500MCG TABLET. Drinking alcohol may hinder vitamin absorption; therefore, it is advised to limit the alcohol intake while using DIACOBAL 500MCG TABLET. DIACOBAL 500MCG TABLET is safe for children only when recommended by the doctor.

Therapeutic Class

VITAMINS

Drug-Drug Interactions

verifiedApollotooltip
MecobalaminChloramphenicol
Moderate
MecobalaminNeomycin
Moderate

Drug-Drug Interactions

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MecobalaminChloramphenicol
Moderate
How does the drug interact with Diacobal 500mcg Tablet:
Coadministration of Diacobal 500mcg Tablet with Chloramphenicol can impair absorption and increase the levels of Diacobal 500mcg Tablet which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Diacobal 500mcg Tablet with Chloramphenicol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
MecobalaminNeomycin
Moderate
How does the drug interact with Diacobal 500mcg Tablet:
Coadministration of Diacobal 500mcg Tablet with Neomycin can impair the absorption of Diacobal 500mcg Tablet and increase its levels which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Diacobal 500mcg Tablet with Neomycin together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of Vomiting, Diarrhoea, Nausea, Headache, or Loss of appetite you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Drug Interactions Checker List

  • NEOMYCIN
  • CHLORAMPHENICOL
  • AMINOSALICYLIC ACID
  • OMEPRAZOLE
  • CIMETIDINE
  • COLCHICINE

Diet & Lifestyle Advise

  • Try Vitamin B complex food sources like milk, cheese, eggs, liver and kidney, chicken, red meat, tuna, mackerel, salmon, shellfish, oysters, clams, dark green vegetables such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.
  • Taking vegetables like acorn squash, asparagus, beet greens, Brussels sprouts, and spinach can help cope with Vitamin B deficiency.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Avoid smoking and alcohol consumption.
  • Exercise regularly and maintain a healthy lifestyle. Avoid excess fatty foods.

Habit Forming

No

Special Advise

 

Disease/Condition Glossary

Vitamin B12 deficiency (cobalamin deficiency): Vitamin B12 deficiency occurs when the body has lower levels of vitamin B12 than normal. Symptoms include fatigue, breathlessness, numbness, poor balance and memory trouble. Pernicious anaemia, an autoimmune disease, is the most common cause of B12 deficiency. In this condition, the body cannot absorb enough vitamin B12 since the body's immune system produces antibodies against the intrinsic factor (a protein that helps the body absorb vitamin B12). Other causes include stomach or gut issues, where the body cannot absorb the vitamin, medications like antidiabetics and stomach-related drugs, and dietary restrictions like being a strict vegan.

Peripheral neuropathy/peripheral neuritis: It is defined as damage to nerves outside the brain and spinal cord. The pain could be intermittent or continuous, with a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Symptoms include spontaneous, un-triggered pain, unpleasant feeling, shooting, burning or stabbing pain, muscle weakness, and cramping.

DIACOBAL 500MCG TABLET Substitute

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