Mantaglial-5 Tablet 10's belongs to a group of medicines called anti-dementia agents used to treat moderate to severe Alzheimer's disease. Alzheimer's disease is a neurological disorder that causes dementia (memory loss), and slowly destroys the ability to think, learn, communicate, and handling daily activities.

Mantaglial-5 Tablet 10's contains 'Memantine' which is an NMDA receptor antagonist. It acts on the N-methyl-D-aspartate (NMDA) receptors involved in transmitting nerve signals that play an essential role in memory. Mantaglial-5 Tablet 10's decreases the brain's abnormal activity and may improve the ability to think and remember or might slow the loss of these abilities in people with Alzheimer's disease.

Take Mantaglial-5 Tablet 10's with or without food. You are advised to take Mantaglial-5 Tablet 10's for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, sleepiness, dizziness, diarrhoea, constipation, balance disorders, and high blood pressure. You are advised to talk to your doctor if you experience any of these side-effects persistently.

Please do not stop taking Mantaglial-5 Tablet 10's without consulting your doctor. Consult your doctor before taking Mantaglial-5 Tablet 10's if you are pregnant or breastfeeding. Avoid driving or operating machinery as Mantaglial-5 Tablet 10's causes dizziness, sleepiness, and may affect reactivity. Avoid consuming alcohol along with Mantaglial-5 Tablet 10's as it could lead to increased dizziness. Mantaglial-5 Tablet 10's is not recommended for children below 18years as the safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Mantaglial-5 Tablet 10's belongs to a group of anti-dementia agents called NMDA receptor antagonist. Mantaglial-5 Tablet 10's is used to treat moderate to severe dementia (memory loss) of Alzheimer's disease. Mantaglial-5 Tablet 10's acts on the N-methyl-D-aspartate (NMDA) receptors involved in transmitting nerve signals which play an important role in memory. Mantaglial-5 Tablet 10's works by decreasing the brain's abnormal activity and may improve the ability to think and remember or might slow the loss of these abilities in people with Alzheimer's disease.

• Headache
• Sleepiness
• Dizziness
• Confusion
• Diarrhea
• Constipation
• Balance disorders
• High blood pressure
• Shortness of breath
• Elevated liver function tests

Do not take Mantaglial-5 Tablet 10's if you are allergic to any of its contents. Inform your doctor if you have/had epilepsy (fits), heart attack, congestive heart failure, or uncontrolled high blood pressure. Talk to your doctor if you change your diet from normal to strict vegetarian or if you are having any kidney problems or urinary tract infections. Avoid taking amantadine (used to treat Parkinson's disease), ketamine (anesthetic), dextromethorphan (used to treat cough), and other NMDA-antagonists at the same time. Consult your doctor before taking Mantaglial-5 Tablet 10's if you are pregnant or breastfeeding. Avoid driving or operating machinery as Mantaglial-5 Tablet 10's causes dizziness, sleepiness, and may affect reactivity. Avoid consuming alcohol along with Mantaglial-5 Tablet 10's as it could lead to increased dizziness. Mantaglial-5 Tablet 10's is not recommended for children below 18years as the safety and effectiveness have not been established.

Drug-Drug Interactions: Mantaglial-5 Tablet 10's may have interaction with antiparkinson's (amantadine), anaesthetic (ketamine), anti-tussive (dextromethorphan), skeletal muscle relaxant (dantrolene, baclofen), antacid (cimetidine, ranitidine), anti-arrhythmic (procainamide, quinidine), anti-malarial (quinine), an alkaloid (nicotine), diuretic (hydrochlorothiazide), dopaminergic agonist (levodopa, bromocriptine), anti-psychotic (quetiapine), anticonvulsants (used to treat fits), barbiturates (used to induce sleep), neuroleptics (used to treat mental disorders), and oral anticoagulants.

Drug-Food Interactions: Avoid alcohol consumption while taking Mantaglial-5 Tablet 10's as it might cause increased dizziness and sleepiness. Avoid smoking as nicotine might interact with the working of Mantaglial-5 Tablet 10's.

Drug-Disease Interactions: Inform your doctor if you have high blood pressure, liver or kidney impairment.

• AMANTADINE
• DEXTROMETHORPHAN
• BACLOFEN
• CIMETIDINE
• RANITIDINE
• PROCAINAMIDE
• QUINIDINE
• QUININE
• NICOTINE
• HYDROCHLOROTHIAZIDE
• LEVODOPA
• BROMOCRIPTINE
• QUETIAPINE
• DANTROLENE
• KETAMINE

• Maintain proper weight by following a healthy diet.
• Exercise regularly as it helps in less cognitive decline and brain volume loss.
• Avoid smoking and alcohol consumption.
• Try to avoid stress by practicing meditation or yoga.
• Include fruits and vegetables in your diet as they contain anti-oxidants.
• Eat nutritious food as it helps in cognitive stimulation.
• Limit foods with high cholesterol and saturated fats.
• Cut down on sugar, salt, and processed foods.
• Drink plenty of water.
• Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.

• Regularly monitor blood pressure levels while taking Mantaglial-5 Tablet 10's as it may cause high blood pressure.

Alzheimer's disease: Alzheimer's disease is a neurological disorder that causes dementia (memory loss), and slowly destroys the ability to think, learn, communicate, and eventually, the ability to handle daily activities. It is the most common cause of dementia (memory loss) in adults. Dementia is the loss of cognitive functioning, such as remembering, thinking, and reasoning. The causes of this disease are abnormal functioning of brain cells which cause a disturbance in communication between them. The risk factors are age, family history, and genetics of a person. Alzheimer's disease symptoms include memory loss, trouble with familiar tasks, difficulties with problem-solving, trouble with writing or talking, disorientation, problems with reasoning or judgment, mood and personality changes. In most people, the symptoms of Alzheimer's appear in their mid-60s.