Pegshine Sugar Free Oral Solution 200 ml

Written By Veda Maddala , M Pharmacy

Reviewed By Hari Kumar , MBBS

Prescription drug

MRP ₹299

(Inclusive of all Taxes)

₹44.9 Cashback (15%)

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Prescription drug

Whats That

About Pegshine Sugar Free Oral Solution

Pegshine Sugar Free Oral Solution belongs to a class of drugs called laxatives used to treat constipation. Constipation refers to infrequent bowel movements in which the stools are often dry, painful, and hard to pass.

Pegshine Sugar Free Oral Solution is a combination of four drugs, namely: Polyethylene glycol, Potassium chloride, Sodium bicarbonate, and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools making them easier to pass. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegshine Sugar Free Oral Solution helps in relieving constipation.

Take Pegshine Sugar Free Oral Solution as advised by your doctor. In some cases, you may experience stomach pain, indigestion, mild diarrhea, nausea, or vomiting. Most of these side effects of Pegshine Sugar Free Oral Solution do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Pegshine Sugar Free Oral Solution or any other medicines, please tell your doctor. If you have ulcerative colitis or Crohn’s disease, inform your doctor before taking Pegshine Sugar Free Oral Solution . Pegshine Sugar Free Oral Solution is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please consult a doctor before taking Pegshine Sugar Free Oral Solution . Drink plenty of fluids while taking Pegshine Sugar Free Oral Solution . Do not take Pegshine Sugar Free Oral Solution in more than the recommended doses.

Uses of Pegshine Sugar Free Oral Solution

Constipation

Directions for Use

Use Pegshine Sugar Free Oral Solution as advised by your doctor. Check the label for directions before use.Oral solution: Dilute it with water as advised by your doctor. Take it by mouth using the measuring cup provided with the pack. Shake the bottle well before each use.Sachet: Dissolve the contents of sachet in water as advised by the doctor. Drink it.

Medicinal Benefits

Pegshine Sugar Free Oral Solution contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools making them easier to pass. Also, it works by cleaning stool from the gastrointestinal tract. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegshine Sugar Free Oral Solution helps in comfortable bowel movement and provides relief from constipation.

Storage

Keep Pegshine Sugar Free Oral Solution out of reach and sight of children.

Side effects of Pegshine Sugar Free Oral Solution 200 ml

Stomach Pain

Drink water or other clear fluids.
To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
Include bland foods like rice, toast, crackers, and rice in your diet.
Avoid lying down immediately after eating as it may cause indigestion or heartburn.
Avoid acidic and spicy food as it may cause indigestion.

Loose/ Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Itching

Here are the few steps for dealing with itching caused by drug use:

Report the itching to your doctor immediately; they may need to change your medication or dosage.
Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
Try not to scratch, as this can worsen the itching and irritate your skin.
If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

If you are allergic to Pegshine Sugar Free Oral Solution or any other medicines, please tell your doctor. If you have ulcerative colitis or Crohn’s disease, inform your doctor before taking Pegshine Sugar Free Oral Solution . Pegshine Sugar Free Oral Solution is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please consult a doctor before taking Pegshine Sugar Free Oral Solution . Drink plenty of fluids while taking Pegshine Sugar Free Oral Solution . Do not take Pegshine Sugar Free Oral Solution in more than the recommended doses. Discard Pegshine Sugar Free Oral Solution after 30 days of first opening the bottle. Do not freeze or refrigerate Pegshine Sugar Free Oral Solution .

Drug-Drug Interactions

Potassium chlorideTrihexyphenidyl

Critical

Potassium chlorideAmitriptyline

Critical

Drug-Drug Interactions

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Potassium chlorideTrihexyphenidyl

Critical

How does the drug interact with Pegshine Sugar Free Oral Solution 200 ml:
Co-administration of trihexyphenidyl with Pegshine Sugar Free Oral Solution 200 ml can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking trihexyphenidyl with Pegshine Sugar Free Oral Solution 200 ml is not recommended as it can possibly result in an interaction, it can be taken if prescribed by a doctor. However, if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, black stools contact a doctor immediately. Do not discontinue any medications without consulting to a doctor.

Potassium chlorideAmitriptyline

Critical

How does the drug interact with Pegshine Sugar Free Oral Solution 200 ml:
The combination of Amitriptyline and Pegshine Sugar Free Oral Solution 200 ml may cause stomach and upper intestinal discomfort. (Only applicable to an oral preparation)

How to manage the interaction:
Although co-administration of Amitriptyline and Pegshine Sugar Free Oral Solution 200 ml is not recommended as it can possibly lead to an interaction, they can be taken if prescribed by a doctor. If you experience severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (in particular with blood), decreased hunger, and black stools while taking these medications, consult a doctor immediately. Do not discontinue any medications without talking to a doctor.

Potassium chlorideEplerenone

Critical

How does the drug interact with Pegshine Sugar Free Oral Solution 200 ml:
Using Eplerenone together with Pegshine Sugar Free Oral Solution 200 ml may significantly increase potassium levels in the blood.

How to manage the interaction:
Taking Pegshine Sugar Free Oral Solution 200 ml with eplerenone is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult the doctor immediately. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.

Potassium chlorideDarifenacin

Critical

How does the drug interact with Pegshine Sugar Free Oral Solution 200 ml:
Taking Darifenacin with Pegshine Sugar Free Oral Solution 200 ml(oral capsule or tablet) can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Darifenacin with Pegshine Sugar Free Oral Solution 200 ml(oral capsule or tablet) is not recommended, as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop taking any medications without doctor's advise.

Potassium chlorideMepenzolate

Critical

How does the drug interact with Pegshine Sugar Free Oral Solution 200 ml:
Taking Mepenzolate and Pegshine Sugar Free Oral Solution 200 ml(in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Mepenzolate with Pegshine Sugar Free Oral Solution 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.

Potassium chlorideDoxepin

Critical

How does the drug interact with Pegshine Sugar Free Oral Solution 200 ml:
Taking Doxepin with Pegshine Sugar Free Oral Solution 200 ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Doxepin with Pegshine Sugar Free Oral Solution 200 ml is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), loss of appetite, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

Potassium chloridePropantheline

Critical

How does the drug interact with Pegshine Sugar Free Oral Solution 200 ml:
Taking Propantheline with Pegshine Sugar Free Oral Solution 200 ml can increase the chance of developing stomach ulcers.

How to manage the interaction:
Taking Propantheline with Pegshine Sugar Free Oral Solution 200 ml is not recommended, as it can lead to an interaction, can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.

Potassium chlorideMeclizine

Critical

How does the drug interact with Pegshine Sugar Free Oral Solution 200 ml:
Taking Meclizine and Pegshine Sugar Free Oral Solution 200 ml (oral form) together can increase the potassium levels in blood.

How to manage the interaction:
Taking Meclizine with Pegshine Sugar Free Oral Solution 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.

Potassium chlorideTolterodine

Critical

How does the drug interact with Pegshine Sugar Free Oral Solution 200 ml:
Taking Tolterodine and Pegshine Sugar Free Oral Solution 200 ml together can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tolterodine and Pegshine Sugar Free Oral Solution 200 ml, they can be taken if prescribed by a doctor. However, contact a doctor immediately if you develop severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), or less desire to eat. Do not discontinue medications without consulting a doctor.

Potassium chlorideOxybutynin

Critical

How does the drug interact with Pegshine Sugar Free Oral Solution 200 ml:
Coadministration of Oxybutynin with Pegshine Sugar Free Oral Solution 200 ml can increase the risk of developing stomach ulcers.

How to manage the interaction:
Taking Oxybutynin with Pegshine Sugar Free Oral Solution 200 ml is generally avoided as it can lead to an interaction, it can be taken when a doctor has prescribed it. Consult the doctor immediately if you experience severe stomach pain, bloating, lightheadedness, dizziness, vomiting (especially with blood), decreased hunger, or dark stools. Do not discontinue any medication without contacting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Try maintaining a balanced diet, which includes fresh fruits and vegetables.
Stay hydrated, drink enough water and fluids.
Exercise regularly, and stay fit.
Get enough sleep.
Eat food rich in fiber such as whole-wheat bread, oatmeal, flaxseed, nuts, beans, lentils, fruits (berries, apples, oranges, bananas, pears, figs), and vegetables (broccoli, spinach, sweet potatoes, avocados).

Side Effects of Pegshine Sugar Free Oral Solution

Stomach pain
Indigestion
Mild diarrhoea
Nausea
Vomiting

Habit Forming

No

Therapeutic Class

LAXATIVES

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Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:40 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Pegshine Sugar Free Oral Solution work?

Pegshine Sugar Free Oral Solution contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools making it easier to pass. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegshine Sugar Free Oral Solution helps in relieving constipation.

Does Pegshine Sugar Free Oral Solution cause diarrhoea?

Pegshine Sugar Free Oral Solution may cause mild diarrhoea as a side effect in the beginning of the treatment. It usually gets better by reducing the amount of Pegshine Sugar Free Oral Solution intake. However, if the condition persists or worsens, please consult a doctor.

Can I take Pegshine Sugar Free Oral Solution with anticonvulsants?

You are not recommended to take Pegshine Sugar Free Oral Solution with anticonvulsants as it may reduce the effectiveness of anticonvulsants (medicines for epilepsy). However, please consult your doctor before taking Pegshine Sugar Free Oral Solution with other medicines.

What foods should I avoid if I’m constipated?

You are recommended to avoid foods that are high in fat and low in fiber such as ice cream, red meat, frozen meals, potato chips, cheese, hot dogs and hamburgers.

Can I take more than advised dose of Pegshine Sugar Free Oral Solution ?

You are not recommended to take more than the advised dose of Pegshine Sugar Free Oral Solution as it may cause excessive diarrhoea that might lead to dehydration. If you have diarrhoea, stop taking Pegshine Sugar Free Oral Solution and drink plenty of fluids to avoid dehydration. However, if the condition persists or worsens, please consult a doctor.

Drug-Drug Interactions Checker List

PHENYTOIN
CARBAMAZEPINE

Disease/Condition Glossary

Constipation: It refers to infrequent bowel movements in which stools are often dry, painful, and hard to pass. Constipation is a condition in which the person has fewer than three bowel movements in a week. However, bowel patterns may vary from person to person. Symptoms include bloating, abdominal pain, and feeling as if the bowel movement is incomplete. Constipation occurs when the large intestine's normal muscle contractions slow down, which causes the incomplete elimination of the bowel from the body. Constipation could be associated with a sudden change of diet, a diet with less fiber, not drinking enough liquids, and a lack of exercise.