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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

About Prexol 1 mg Tablet 15's

Prexol 1 mg Tablet 15's belongs to a group of antiparkinson agents or dopamine agonists used to treat the symptoms of Parkinson’s disease and moderate to severe Willis-Ekbom disease (restless legs syndrome) in adults. Parkinson’s disease is a progressive neurological disorder in which the first signs are problems with movements. Willis-Ekbom disease is a condition which causes the uncontrollable urge to move the legs.

Prexol 1 mg Tablet 15's contains 'Pramipexole' that works by mimicking the action of dopamine (acting in place of dopamine), a natural substance found in the brain needed to control body movement. This triggers the nerve impulses in the brain that control body movements.

In some cases, you may experience certain common side-effects such as sleepiness, nausea, constipation, dizziness, fatigue, hallucinations, dry mouth, muscle spasms, and peripheral oedema (leg swelling due to fluid overload). Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Do not discontinue Prexol 1 mg Tablet 15's on your own. Consult your doctor if you are pregnant or breastfeeding. Prexol 1 mg Tablet 15's may cause drowsiness and dizziness, do not drive unless you are alert. Prexol 1 mg Tablet 15's should not be used in children below 18 years. Avoid consuming alcohol along with Prexol 1 mg Tablet 15's as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as Prexol 1 mg Tablet 15's may cause orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). 

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

PRAMIPEXOLE-1MG

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Prexol 1 mg Tablet 15's

Parkinson’s disease, Willis Ekbom disease (restless legs syndrome)

Medicinal Benefits

Prexol 1 mg Tablet 15's belongs to a group of antiparkinson agents called dopamine agonists used to treat the symptoms of Parkinson’s disease and moderate to severe Willis-Ekbom disease (restless legs syndrome) in adults. Prexol 1 mg Tablet 15's binds to the dopamine receptor and mimics its action. Dopamine is a naturally-occurring neurotransmitter in the brain. Dopamine is absent or reduced in people with Parkinson’s disease. Prexol 1 mg Tablet 15's works by stimulating the dopamine receptors in the brain. This triggers the nerve impulses in the brain that control body movements. Prexol 1 mg Tablet 15's helps in relieving the symptoms of Parkinson’s disease, such as muscle spasms, tremors, stiffness, and poor muscle control.

Side Effects of Prexol 1 mg Tablet 15's

  • Nausea
  • Low blood pressure
  • Dizziness
  • Constipation
  • Fatigue
  • Headache
  • Dry mouth
  • Muscle spasms

Directions for Use

Swallow Prexol 1 mg Tablet 15's as a whole with water; do not crush, break or chew it. For restless leg syndrome: Prexol 1 mg Tablet 15's should be taken 2-3 hours before bedtime.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Prexol 1 mg Tablet 15's if you are allergic to any of its contents. Talk to your doctor before taking Prexol 1 mg Tablet 15's if you have kidney problems, hallucinations, dyskinesia (abnormal limb movements), dystonia (inability to keep the neck straight), sleepiness or suddenly falling asleep, psychosis, vision impairment, severe heart or blood vessel disease, or augmentation (symptoms start earlier). Inform your doctor if you experience symptoms such as apathy, anxiety, depression, fatigue, sweating or pain after dose reduction or stopping Prexol 1 mg Tablet 15's. Prexol 1 mg Tablet 15's may cause intense urges such as increased sex drive, gambling, overeating and wasting money. Consult your doctor if you are pregnant or breastfeeding. Prexol 1 mg Tablet 15's may cause drowsiness and dizziness, do not drive unless you are alert. Prexol 1 mg Tablet 15's should not be given to children below 18 years. Avoid consuming alcohol along with Prexol 1 mg Tablet 15's as it could lead to increased drowsiness and dizziness. Rise slowly from sitting or lying position as Prexol 1 mg Tablet 15's causes orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). 

Therapeutic Class

ANTIPARKINSON AGENTS

Drug-Drug Interactions

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PramipexoleRisperidone
Critical
PramipexoleOlanzapine
Critical

Drug-Drug Interactions

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PramipexoleRisperidone
Critical
How does the drug interact with Prexol 1 mg Tablet 15's:
Taking Risperidone with Prexol 1 mg Tablet 15's may reduce the effectiveness of Prexol 1 mg Tablet 15's.

How to manage the interaction:
Taking Risperidone with Prexol 1 mg Tablet 15's is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, and lightheadedness contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PramipexoleOlanzapine
Critical
How does the drug interact with Prexol 1 mg Tablet 15's:
Taking Olanzapine with Prexol 1 mg Tablet 15's can increase the risk and severity of side effects and reduce the effectiveness of Prexol 1 mg Tablet 15's.

How to manage the interaction:
Co-administration of Olanzapine and Prexol 1 mg Tablet 15's is not recommended as it leads to an interaction, it can be taken if advised by a doctor. If you experience any symptoms such as drowsiness, dizziness, and lightheadedness, contact a doctor immediately. Avoid driving or operating dangerous machinery, and be careful while getting up from a sitting or lying position. Do not discontinue any medications without consulting a doctor.
PramipexoleEsketamine
Severe
How does the drug interact with Prexol 1 mg Tablet 15's:
Taking Esketamine with Prexol 1 mg Tablet 15's may increase the risk of side effects.

How to manage the interaction:
Although taking Prexol 1 mg Tablet 15's and Esketamine together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any symptoms like drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination, consult a doctor. Do not discontinue any medications without a doctor's advice.
PramipexoleAmisulpride
Severe
How does the drug interact with Prexol 1 mg Tablet 15's:
Taking Amisulpride with Prexol 1 mg Tablet 15's may decrease the efficacy of both medications.

How to manage the interaction:
Although taking amisulpride along with Prexol 1 mg Tablet 15's can result in an interaction, it can be taken if a doctor has advised it. Avoid jobs that demand mental awareness and exercise caution while rising from a sitting or sleeping posture. Do not discontinue any medications without a doctor's advice.
PramipexoleSodium oxybate
Severe
How does the drug interact with Prexol 1 mg Tablet 15's:
Taking Sodium oxybate with Prexol 1 mg Tablet 15's may increase the risk of side effects.

How to manage the interaction:
Taking Prexol 1 mg Tablet 15's with Sodium oxybate together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult a doctor. Do not discontinue the medications without consulting a doctor.
PramipexoleSodium oxybate
Severe
How does the drug interact with Prexol 1 mg Tablet 15's:
Taking Sodium oxybate with Prexol 1 mg Tablet 15's may increase he risk of side effects.

How to manage the interaction:
Taking Prexol 1 mg Tablet 15's with Sodium oxybate together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination, consult a doctor. Do not discontinue any medications without a doctor's advice.
PramipexoleEsketamine
Severe
How does the drug interact with Prexol 1 mg Tablet 15's:
Combining Esketamine with Prexol 1 mg Tablet 15's may increase side effects

How to manage the interaction:
Although taking Prexol 1 mg Tablet 15's and Esketamine together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any symptoms like drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination, consult a doctor. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMITRIPTYLINE
  • DULOXETINE
  • TRAZODONE
  • FLUOXETINE
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • GABAPENTIN
  • PREGABALIN
  • MEMANTINE
  • ACETAMINOPHEN
  • HYDROCODONE
  • TRAMADOL

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include a diet rich in iron, folate and magnesium. 
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Habit Forming

No

Special Advise

Patients and their caretakers (midwife/nurse) should be alerted as Prexol 1 mg Tablet 15's may cause intense urges such as increased sex drive, gambling, overeating and wasting money.

Author Details

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Disease/Condition Glossary

Parkinson’s disease: It is a progressive neurological disorder in which the first signs are problems with movements. Dopamine is a naturally-occurring neurotransmitter in the brain which is reduced or absent in people with Parkinson’s disease. Due to this problems arise with smooth and coordinated movements. Symptoms include decreased ability to smell, stooped posture, changes in voice, constipation, small/cramped handwriting, tremor, slow movements, stiffness of arms, legs, and trunk, and problems with balance. 

Willis-Ekbom disease (restless leg syndrome): It is a condition which causes the uncontrollable urge to move the legs. The urge to move their legs is more intense when a person is trying to sleep or relax. This interferes with sleep leading to daytime sleepiness and fatigue. Symptoms include an uncontrollable urge to move the legs, tingling, crawling or pulling sensations in the legs.

Prexol 1 mg Tablet 15's Substitute

Substitutes safety advice
  • Pramipex 1 Tablet 10's

    21.29per tablet
  • Pramirol-1 Tablet 10's

    27.09per tablet
  • Pexopram 1 mg Tablet 10's

    17.01per tablet
  • Pramiset-1 Tablet 10's

    18.90per tablet
  • Mirator 1 mg Tablet 10's

    12.69per tablet
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