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  1. Home
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  3. Zybol Oral Gel

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About Zybol Oral Gel

Zybol Oral Gel belongs to a group of medicines called antacids & anti-ulcerants used to treat acidity, bloating, indigestion, heartburn, and gas. The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity and heartburn. Bloating occurs when the abdomen is filled with gas or air.

Zybol Oral Gel is a combination of two drugs: Magaldrate (antacid) and Simethicone (anti-flatulent). Magaldrate works by neutralising excess stomach acid. Simethicone works by decreasing the surface tension of gas bubbles, thereby facilitating the expulsion of gas through flatus or belching (burping). It also prevents the accumulation and formation of gas in the digestive tract.

Take Zybol Oral Gel with or without food. You are advised to take Zybol Oral Gel for as long as your doctor has suggested it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as constipation, diarrhoea, and intestinal pain. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Avoid taking aluminium and magnesium-containing antacids with Zybol Oral Gel. Aluminium-containing antacids along with Zybol Oral Gel could lead to constipation and intestinal obstruction, whereas magnesium-containing antacids might cause diarrhoea. Consult your doctor if you are pregnant or breastfeeding. Zybol Oral Gel should not be given to children as safety has not been established. Avoid consuming alcohol along with Zybol Oral Gel as it could lead to increased acidity.

Uses of Zybol Oral Gel

Acidity, bloating, indigestion, heartburn, and gas.

Medicinal Benefits

Zybol Oral Gel belongs to a group of medicines called antacids, anti ulcerants used to treat acidity, bloating, indigestion, heartburn, and gas. Zybol Oral Gel is a combination of two drugs: Magaldrate (antacid) and Simethicone (anti-flatulent). Magaldrate works by neutralising excess stomach acid. Simethicone is a mixture of silica gel and dimethicone. It is also known as activated dimethicone. Simethicone works by decreasing the surface tension of gas bubbles, thereby facilitates the expulsion of gas through flatus or belching (burping). It also prevents accumulation and formation of gas in the digestive tract.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops/Gel: Take the suggested dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.Chewable tablet: Chew the tablet completely and swallow. Do not swallow it as a whole.

Storage

Keep Zybol Oral Gel out of reach and sight of children.

Side Effects of Zybol Oral Gel

  • Constipation
  • Diarrhoea
  • Intestinal pain

Drug Warnings

Do not take Zybol Oral Gel if you are allergic to any of its contents. Inform your doctor before taking Zybol Oral Gel if you have a history of appendicitis, blockage of the bowel, rectal bleeding, kidney problems; if you are on a low-magnesium diet, or if you have undergone recent bowel surgery. Avoid taking aluminium and magnesium-containing antacids with Zybol Oral Gel. Aluminium-containing antacids along with Zybol Oral Gel could lead to constipation and intestinal obstruction, whereas magnesium-containing antacids might cause diarrhoea. Consult your doctor if you are pregnant or breastfeeding. Zybol Oral Gel should not be given to children as safety has not been established. Avoid consuming alcohol along with Zybol Oral Gel as it could lead to increased acidity. 

Drug Interactions

Drug-Drug Interactions: Zybol Oral Gel may have interaction with anti-hypertensive (Ramipril), hormone (levothyroxine), anti-convulsant (phenytoin), and antacids (aluminium hydroxide, magnesium hydroxide).

Drug-Food Interactions: Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

Drug-Disease Interaction: Inform your doctor if you have renal dysfunction.

Drug-Drug Interactions Checker List

  • RAMIPRIL
  • LEVOTHYROXINE SODIUM
  • PHENYTOIN
  • MAGNESIUM HYDROXIDE
  • ALUMINUM HYDROXIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating to prevent acid backflow.
  • Avoid tight-fitting clothes.
  • Maintain a healthy weight by regular exercising.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Disease/Condition Glossary

The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity. Due to this, acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing. Indigestion is the feeling of fullness. It occurs due to slow gastric emptying. Symptoms include stomach pain, bloating, heartburn, nausea and vomiting. Bloating occurs when the abdomen is filled with gas or air. Flatulence occurs when gas collects inside the digestive system.

Consult Doctor

About Zybol Oral Gel

Zybol Oral Gel belongs to a group of medicines called antacids & anti-ulcerants used to treat acidity, bloating, indigestion, heartburn, and gas. The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity and heartburn. Bloating occurs when the abdomen is filled with gas or air.

Zybol Oral Gel is a combination of two drugs: Magaldrate (antacid) and Simethicone (anti-flatulent). Magaldrate works by neutralising excess stomach acid. Simethicone works by decreasing the surface tension of gas bubbles, thereby facilitating the expulsion of gas through flatus or belching (burping). It also prevents the accumulation and formation of gas in the digestive tract.

Take Zybol Oral Gel with or without food. You are advised to take Zybol Oral Gel for as long as your doctor has suggested it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as constipation, diarrhoea, and intestinal pain. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Avoid taking aluminium and magnesium-containing antacids with Zybol Oral Gel. Aluminium-containing antacids along with Zybol Oral Gel could lead to constipation and intestinal obstruction, whereas magnesium-containing antacids might cause diarrhoea. Consult your doctor if you are pregnant or breastfeeding. Zybol Oral Gel should not be given to children as safety has not been established. Avoid consuming alcohol along with Zybol Oral Gel as it could lead to increased acidity.

Zybol Oral Gel, Pack of 1 Oral Gel
COD available

Online payment accepted

Available Offers

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Composition :

MAGALDRATE-400MG + SIMETHICONE-20MG

Manufacturer/Marketer :

ZEGCHEM

Consume Type :

ORAL

Return Policy :

Not Returnable

Country of origin

India
Other Info - ZY99130

FAQs

Zybol Oral Gel is a combination of two drugs: Magaldrate (antacid) and Simethicone (anti-flatulent). Magaldrate works by neutralising excess stomach acid. Simethicone works by decreasing the surface tension of gas bubbles, thereby facilitates the expulsion of gas through flatus or belching (burping). It also prevents accumulation and formation of gas in the digestive tract.

Talk to your doctor if you do not feel better even after taking Zybol Oral Gel for 14days. Do not take Zybol Oral Gel for longer durations unless suggested by the doctor.

Diarrhoea might be a side-effect of Zybol Oral Gel. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Avoid lying down immediately after meals to prevent acidity. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This prevents acid reflux.

Avoid taking aluminium and magnesium-containing antacids with Zybol Oral Gel. Aluminium containing antacids along with Zybol Oral Gel could lead to constipation and intestinal obstruction, whereas magnesium-containing antacids might cause diarrhoea.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Zybol Oral Gel. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

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Pregnancy

Caution

Consult your doctor, and there is no substantial research yet on the use of Zybol Oral Gel in pregnancy. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Consult your doctor before taking Zybol Oral Gel; your doctor will decide whether Zybol Oral Gel can be taken by breastfeeding mothers or not.

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Driving

Safe if suggested

Zybol Oral Gel does not affect your ability to drive.

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Liver

Caution

Consult your doctor before taking Zybol Oral Gel if you have a liver impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

Consult your doctor before taking Zybol Oral Gel if you have kidney impairment or any concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Children

Unsafe

Zybol Oral Gel should not be given to children as the safety and effectiveness were not established.

Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:31 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/sfx/magaldrate-simethicone-side-effects.html
  2. https://www.npra.gov.my/images/reg-and-noti/PI/non-poison/Simethicone_Tablet_Capsule.pdf

Uses of Zybol Oral Gel

Acidity, bloating, indigestion, heartburn, and gas.

Medicinal Benefits

Zybol Oral Gel belongs to a group of medicines called antacids, anti ulcerants used to treat acidity, bloating, indigestion, heartburn, and gas. Zybol Oral Gel is a combination of two drugs: Magaldrate (antacid) and Simethicone (anti-flatulent). Magaldrate works by neutralising excess stomach acid. Simethicone is a mixture of silica gel and dimethicone. It is also known as activated dimethicone. Simethicone works by decreasing the surface tension of gas bubbles, thereby facilitates the expulsion of gas through flatus or belching (burping). It also prevents accumulation and formation of gas in the digestive tract.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops/Gel: Take the suggested dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.Chewable tablet: Chew the tablet completely and swallow. Do not swallow it as a whole.

Storage

Keep Zybol Oral Gel out of reach and sight of children.

Drug Warnings

Do not take Zybol Oral Gel if you are allergic to any of its contents. Inform your doctor before taking Zybol Oral Gel if you have a history of appendicitis, blockage of the bowel, rectal bleeding, kidney problems; if you are on a low-magnesium diet, or if you have undergone recent bowel surgery. Avoid taking aluminium and magnesium-containing antacids with Zybol Oral Gel. Aluminium-containing antacids along with Zybol Oral Gel could lead to constipation and intestinal obstruction, whereas magnesium-containing antacids might cause diarrhoea. Consult your doctor if you are pregnant or breastfeeding. Zybol Oral Gel should not be given to children as safety has not been established. Avoid consuming alcohol along with Zybol Oral Gel as it could lead to increased acidity. 

Therapeutic Class

ANTACIDS, ANTIULCERANTS

Drug-Drug Interactions Checker List

  • RAMIPRIL
  • LEVOTHYROXINE SODIUM
  • PHENYTOIN
  • MAGNESIUM HYDROXIDE
  • ALUMINUM HYDROXIDE

Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating to prevent acid backflow.
  • Avoid tight-fitting clothes.
  • Maintain a healthy weight by regular exercising.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Side Effects of Zybol Oral Gel

  • Constipation
  • Diarrhoea
  • Intestinal pain

Disease/Condition Glossary

The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity. Due to this, acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing. Indigestion is the feeling of fullness. It occurs due to slow gastric emptying. Symptoms include stomach pain, bloating, heartburn, nausea and vomiting. Bloating occurs when the abdomen is filled with gas or air. Flatulence occurs when gas collects inside the digestive system.

Zybol Oral Gel Substitute

Substitutes safety advice

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