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About Osarten AH 40mg/5mg/12.5mg Tablet

Osarten AH 40mg/5mg/12.5mg Tablet belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications.

Osarten AH 40mg/5mg/12.5mg Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Osarten AH 40mg/5mg/12.5mg Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Depending upon your medical condition, you are advised to take Osarten AH 40mg/5mg/12.5mg Tablet for as long as your doctor has prescribed it for you. The most common side effects of Osarten AH 40mg/5mg/12.5mg Tablet are nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, headache, feeling exhausted, swollen ankles, dizziness, and decreased blood pressure in some cases. Most of these side effects of Osarten AH 40mg/5mg/12.5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless your doctor tells you. In rare cases, Osarten AH 40mg/5mg/12.5mg Tablet can cause a condition that results in a skeletal muscle problem, leading to further kidney failure. If you notice unexplained muscle pain, dark-coloured urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase heart disease and stroke risk. Inform your doctor if you are suffering from kidney, liver, heart disease, or diabetes. If you are pregnant or breastfeeding, do not take Osarten AH 40mg/5mg/12.5mg Tablet as it is a category D pregnancy drug and may harm the baby. Do not use the Osarten AH 40mg/5mg/12.5mg Tablet if you cannot urinate, are dehydrated, have low blood pressure (hypotension), or have had cardiogenic shock (sudden stopping blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to this medicine. Reducing table salt (sodium chloride) in your food often helps lower blood pressure.

Uses of Osarten AH 40mg/5mg/12.5mg Tablet

Hypertension (high blood pressure)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Osarten AH 40mg/5mg/12.5mg Tablet belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. Osarten AH 40mg/5mg/12.5mg Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Osarten AH 40mg/5mg/12.5mg Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Storage

Keep Osarten AH 40mg/5mg/12.5mg Tablet out of the sight and reach of children.

Drug Warnings

Do not use Osarten AH 40mg/5mg/12.5mg Tablet if you are pregnant, planning for pregnancy, or unable to urinate (anuria). If you have diabetes and taking Osarten AH 40mg/5mg/12.5mg Tablet with other blood pressure-lowering pills like 'aliskiren,' immediately stop taking both together and consult a doctor. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Osarten AH 40mg/5mg/12.5mg Tablet may pass into breast milk, so before starting Osarten AH 40mg/5mg/12.5mg Tablet, either you need to stop nursing or you should not take Osarten AH 40mg/5mg/12.5mg Tablet while breastfeeding. Please inform your doctor before surgery if you are taking Osarten AH 40mg/5mg/12.5mg Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia. Avoid potassium salt or its substitute intake while using Osarten AH 40mg/5mg/12.5mg Tablet to avoid any electrolyte imbalance. Osarten AH 40mg/5mg/12.5mg Tablet can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Osarten AH 40mg/5mg/12.5mg Tablet and breastfeeding.

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AmlodipineDantrolene
Critical

Drug-Drug Interactions

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How does the drug interact with Osarten AH 40mg/5mg/12.5mg Tablet:
Using aliskiren together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).

How to manage the interaction:
Taking Osarten AH 40mg/5mg/12.5mg Tablet with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
AmlodipineDantrolene
Critical
How does the drug interact with Osarten AH 40mg/5mg/12.5mg Tablet:
Using Osarten AH 40mg/5mg/12.5mg Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Osarten AH 40mg/5mg/12.5mg Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Osarten AH 40mg/5mg/12.5mg Tablet:
Taking Cisapride and Osarten AH 40mg/5mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Osarten AH 40mg/5mg/12.5mg Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Osarten AH 40mg/5mg/12.5mg Tablet:
Taking Dofetilide and Osarten AH 40mg/5mg/12.5mg Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Osarten AH 40mg/5mg/12.5mg Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Osarten AH 40mg/5mg/12.5mg Tablet:
Taking ramipril together with olmesartan may increase the risk of side effects (blood pressure, kidney function impairment, and a condition called Hyperkalemia - high blood potassium).

How to manage the interaction:
Although taking Osarten AH 40mg/5mg/12.5mg Tablet with ramipril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Osarten AH 40mg/5mg/12.5mg Tablet:
Using Osarten AH 40mg/5mg/12.5mg Tablet with Potassium chloride may increase Potassium levels in the blood.

How to manage the interaction:
Although taking Osarten AH 40mg/5mg/12.5mg Tablet together with Potassium chloride may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
How does the drug interact with Osarten AH 40mg/5mg/12.5mg Tablet:
Coadministration of Osarten AH 40mg/5mg/12.5mg Tablet with enalapril can elevate the risk of adverse effects such as low blood pressure, kidney impairment, and hyperkalemia (high blood potassium). Hyperkalemia can cause kidney failure, strong paralysis, abnormal heart rhythm, and cardiac arrest in extreme instances. If you are elderly, dehydrated, or have renal disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Although taking Osarten AH 40mg/5mg/12.5mg Tablet together with enalapril may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Osarten AH 40mg/5mg/12.5mg Tablet:
Osarten AH 40mg/5mg/12.5mg Tablet when combined with benazepril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Osarten AH 40mg/5mg/12.5mg Tablet with benazepril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Osarten AH 40mg/5mg/12.5mg Tablet:
Taking Osarten AH 40mg/5mg/12.5mg Tablet with triamterene may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Osarten AH 40mg/5mg/12.5mg Tablet with triamterene may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Osarten AH 40mg/5mg/12.5mg Tablet:
When Osarten AH 40mg/5mg/12.5mg Tablet is taken with captopril, it may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Osarten AH 40mg/5mg/12.5mg Tablet with captopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
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AMLODIPINE-5MG+HYDROCHLOROTHIAZIDE-12.5MG+OLMESARTAN MEDOXOMIL-40MGPotassium rich foods
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+HYDROCHLOROTHIAZIDE-12.5MG+OLMESARTAN MEDOXOMIL-40MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Osarten AH 40mg/5mg/12.5mg Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Osarten AH 40mg/5mg/12.5mg Tablet.

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Be mindful of salt; consume no more than 2,300 mg each day.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of heart disease.

Side Effects of Osarten AH 40mg/5mg/12.5mg Tablet

  • Nausea
  • Upset stomach
  • Dehydration
  • Headache
  • Dry mouth
  • Muscle cramps/weakness
  • Fast/slow/irregular heartbeat
  • Diarrhoea
  • Electrolyte imbalance
  • Headache
  • Feeling exhausted
  • Swollen ankles
  • Dizziness
  • Decreased blood pressure

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES
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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • LITHIUM
  • DIGOXIN
  • ASPIRIN
  • METFORMIN
  • INSULIN
  • SILDENAFIL
  • SIMVASTATIN
  • CYCLOSPORINE
  • ATENOLOL
  • ALISKIREN
  • ENALAPRIL
  • LISINOPRIL
  • RAMIPRIL
  • METOPROLOL
  • IBUPROFEN
  • CARBENOXOLONE

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force our heart uses to pump blood to all body parts. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). High blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

Have a query?

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Alcohol

Unsafe

You are recommended not to consume alcohol and Osarten AH 40mg/5mg/12.5mg Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

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Pregnancy

Unsafe

Osarten AH 40mg/5mg/12.5mg Tablet is not recommended during pregnancy as it contains Olmesartan, which is a category D pregnancy drug. This medicine may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Unsafe

Osarten AH 40mg/5mg/12.5mg Tablet is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this. Either you need to stop breastfeeding for using Osarten AH 40mg/5mg/12.5mg Tablet or stop taking Osarten AH 40mg/5mg/12.5mg Tablet.

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Driving

Caution

Drive with caution; Osarten AH 40mg/5mg/12.5mg Tablet usually causes drowsiness and affects driving ability.

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Liver

Caution

Osarten AH 40mg/5mg/12.5mg Tablet to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Osarten AH 40mg/5mg/12.5mg Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Caution

Efficacy and safety of Osarten AH 40mg/5mg/12.5mg Tablet have not been established in children. If prescribed, it should be strictly under medical supervision and only if the benefits outweigh the harm.

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