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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Composition :

MERCAPTOPURINE-50MG

Manufacturer/Marketer :

Cadila Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About 6-MP Tablet

6-MP Tablet belongs to the class of medication called anticancer drugs used in the treatment of blood cancer. Blood cancer also known as leukaemia, is the cancer of blood cells. It causes excessive production of immature white blood cells by the bone marrow.

6-MP Tablet contains Mercaptopurine that works by interfering with the production of genetic material (DNA and RNA) in the cancer cells that are essential for growth, repair and multiplication of cells. Thus, 6-MP Tablet stops multiplication of abnormal cells and leads to the growth of cells in an unbalanced way and causes the death of cells.

Take 6-MP Tablet as prescribed by your doctor. You are advised to take 6-MP Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience vomiting, nausea, low red blood cell count, loss of appetite, diarrhoea or inflammation of the mouth. Most of these side effects of 6-MP Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to 6-MP Tablet or any other medicines, please tell your doctor. Avoid taking 6-MP Tablet if you are pregnant or breastfeeding and consult a doctor. You are recommended to use effective contraceptive methods while using 6-MP Tablet and for 3 months after completing the course of 6-MP Tablet to prevent pregnancy. 6-MP Tablet should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar. Avoid excessive exposure to sunlight as 6-MP Tablet may cause sensitivity to sunlight. You are advised to use a sunscreen with a high protection factor and wear protective clothing while going out. 6-MP Tablet may increase the risk of a serious condition called macrophage activation syndrome (over activation of white blood cells associated with inflammation), especially in people with arthritis.

Uses of 6-MP Tablet

Blood cancer (Acute lymphoblastic leukaemia) 

Directions for Use

Take 6-MP Tablet with or without food as advised by your doctor preferably 1 hour before or 2 hours after taking milk or dairy products. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

6-MP Tablet contains Mercaptopurine, an anticancer drug used to treat blood cancer. 6-MP Tablet interferes with the production of genetic material (DNA and RNA) in the cancer cells essential for growth, repair and multiplication of cells. Thus, 6-MP Tablet stops multiplication of abnormal cells and leads to cell's growth in an unbalanced way and causes the death of cells. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of 6-MP Tablet

  • Nausea
  • Vomiting
  • Low red blood cell count
  • Loss of appetite
  • Diarrhoea
  • Inflammation of the mouth

Drug Warnings

If you are allergic to 6-MP Tablet or any other medicines, please tell your doctor. Avoid taking 6-MP Tablet if you are pregnant or breastfeeding and consult a doctor. You are recommended to use effective contraceptive methods while using 6-MP Tablet and 3 months after completing the course of 6-MP Tablet to prevent pregnancy. 6-MP Tablet should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar. 6-MP Tablet may increase the risk of infections. Therefore, consult your doctor if you notice any infection signs such as urinary problems, sore throat or mouth. Avoid excessive exposure to sunlight as 6-MP Tablet may cause sensitivity to sunlight. You are advised to use a sunscreen with a high protection factor and wear protective clothing while going out. 6-MP Tablet may increase the risk of a serious condition called macrophage activation syndrome (over activation of white blood cells associated with inflammation), especially in people with arthritis. If you are about to receive any vaccinations, inform your doctor that you are taking 6-MP Tablet to cause infections. 

Drug-Drug Interactions

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MercaptopurineTalimogene laherparepvec
Critical
MercaptopurineYellow fever vaccine
Critical

Drug-Drug Interactions

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MercaptopurineTalimogene laherparepvec
Critical
How does the drug interact with 6-MP Tablet:
Co-administration of Talimogene laherparepvec with 6-MP Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking 6-MP Tablet with Talimogene laherparepvec is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
MercaptopurineYellow fever vaccine
Critical
How does the drug interact with 6-MP Tablet:
Co-administration of the Yellow fever vaccine with 6-MP Tablet can increase the risk of infection.

How to manage the interaction:
Taking 6-MP Tablet with the Yellow fever vaccine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
MercaptopurineRotavirus vaccine
Critical
How does the drug interact with 6-MP Tablet:
When Rotavirus vaccine is used together with 6-MP Tablet, its effectiveness may be reduced.

How to manage the interaction:
Taking 6-MP Tablet with the Rotavirus vaccine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
MercaptopurineFebuxostat
Critical
How does the drug interact with 6-MP Tablet:
Coadministration of 6-MP Tablet with Febuxostat can increase the blood levels of 6-MP Tablet.

How to manage the interaction:
Taking 6-MP Tablet with Febuxostat is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
MercaptopurineBCG vaccine
Critical
How does the drug interact with 6-MP Tablet:
Co-administration of the BCG vaccine with 6-MP Tablet together can increase the risk of infection.

How to manage the interaction:
Taking 6-MP Tablet with BCG vaccine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
MercaptopurineEtanercept
Severe
How does the drug interact with 6-MP Tablet:
Co-administration of Etanercept with 6-MP Tablet together can increase the risk of infections.

How to manage the interaction:
Although taking Etanercept and 6-MP Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
MercaptopurineCladribine
Severe
How does the drug interact with 6-MP Tablet:
Co-administration of Cladribine with 6-MP Tablet together can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and 6-MP Tablet, but it can be taken if prescribed by a doctor. If you have any of these symptoms, contact your doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not stop using any medications without a doctor's advice.
MercaptopurineLeflunomide
Severe
How does the drug interact with 6-MP Tablet:
Co-administration of 6-MP Tablet with Leflunomide can increase the risk of infections and liver problems.

How to manage the interaction:
Although there is an interaction between leflunomide and 6-MP Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MercaptopurineInfliximab
Severe
How does the drug interact with 6-MP Tablet:
Co-administration of Infliximab with 6-MP Tablet can increase the risk of infection.

How to manage the interaction:
Taking 6-MP Tablet with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, contact your doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not discontinue any medications without consulting a doctor.
MercaptopurineCertolizumab
Severe
How does the drug interact with 6-MP Tablet:
Co-administration of 6-MP Tablet with Certolizumab can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between 6-MP Tablet and Certolizumab, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, contact your doctor immediately - fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning when you pee. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking 6-MP Tablet as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

6-MP Tablet Substitute

Substitutes safety advice
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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

6-MP Tablet contains Mercaptopurine that works by interfering with the production of genetic material (DNA and RNA) in the cancer cells that are essential for growth, repair and multiplication of cells. Thus, 6-MP Tablet stops multiplication of abnormal cells and leads to the growth of cells in an unbalanced way and causes the death of cells.

6-MP Tablet may affect eggs or cause low sperm count. Therefore, please consult a doctor before taking 6-MP Tablet if you are planning to become parents.

6-MP Tablet may increase sensitivity to sunlight or UV light. Therefore, avoid or limit exposure to the sun for a long time or artificial light such as tanning beds. Wear protective clothing and use a sunscreen before going out in the sun.

6-MP Tablet may cause low blood sugar levels in children below 6 years and those having low body weight. Therefore, use 6-MP Tablet with caution in children and if you notice any symptoms such as dizziness, excessive sweating, confusion or nausea, please consult a doctor immediately.

If you are about to receive any vaccinations especially live vaccines such as measles vaccine, flu vaccine, BCG vaccine, etc., it is advised to inform your doctor that you are on treatment with 6-MP Tablet as it may cause infections.

6-MP Tablet may increase the risk of infections. Therefore, consult your doctor if you notice any signs of infection such as urinary problems, chills, fever, cough, sore throat or mouth and avoid contact with people having cold, flu or infection.

Drug-Drug Interactions Checker List

  • FEBUXOSTAT
  • ALLOPURINOL
  • MESALAZINE
  • SULFASALAZINE
  • WARFARIN
  • ACENOCOUMAROL
  • INFLIXIMAB
  • PHENYTOIN
  • CARBAMAZEPINE
  • RIBAVIRIN
  • THIOPURINOL
  • OXIPURINOL
  • OLSALAZINE

Special Advise

  • Regular blood and urine tests are recommended while taking 6-MP Tablet to monitor the number of red blood cells, platelets, white blood cells, uric acid levels, kidney or liver functioning.
  • Do not receive any vaccination during treatment without your doctor's approval while taking 6-MP Tablet . 

Disease/Condition Glossary

Blood cancer: It is the cancer of blood cells, also known as leukaemia. It causes excessive production of immature white blood cells by the bone marrow. The symptoms include unintentional weight loss, weakness, excessive sweating, tiredness, bone pain, frequent infections, chills or fever, red spots on the skin or painless, swollen lymph nodes, especially in the armpits neck.  The risk factors of leukaemia include smoking, genetic or blood disorders, family history of leukaemia, exposure to high radiation levels, or previous cancer treatment with radiation or chemotherapy.

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