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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS

About Merinethol 50 mg Tablet 10's

Merinethol 50 mg Tablet 10's belongs to the class of medication called anticancer drugs used in the treatment of blood cancer. Blood cancer also known as leukaemia, is the cancer of blood cells. It causes excessive production of immature white blood cells by the bone marrow.

Merinethol 50 mg Tablet 10's contains Mercaptopurine that works by interfering with the production of genetic material (DNA and RNA) in the cancer cells that are essential for growth, repair and multiplication of cells. Thus, Merinethol 50 mg Tablet 10's stops multiplication of abnormal cells and leads to the growth of cells in an unbalanced way and causes the death of cells.

Take Merinethol 50 mg Tablet 10's as prescribed by your doctor. You are advised to take Merinethol 50 mg Tablet 10's for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience vomiting, nausea, low red blood cell count, loss of appetite, diarrhoea or inflammation of the mouth. Most of these side effects of Merinethol 50 mg Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Merinethol 50 mg Tablet 10's or any other medicines, please tell your doctor. Avoid taking Merinethol 50 mg Tablet 10's if you are pregnant or breastfeeding and consult a doctor. You are recommended to use effective contraceptive methods while using Merinethol 50 mg Tablet 10's and for 3 months after completing the course of Merinethol 50 mg Tablet 10's to prevent pregnancy. Merinethol 50 mg Tablet 10's should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar. Avoid excessive exposure to sunlight as Merinethol 50 mg Tablet 10's may cause sensitivity to sunlight. You are advised to use a sunscreen with a high protection factor and wear protective clothing while going out. Merinethol 50 mg Tablet 10's may increase the risk of a serious condition called macrophage activation syndrome (over activation of white blood cells associated with inflammation), especially in people with arthritis.

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Merinethol 50 mg Tablet 10's

Blood cancer (Acute lymphoblastic leukaemia) 

Medicinal Benefits

Merinethol 50 mg Tablet 10's contains Mercaptopurine, an anticancer drug used to treat blood cancer. Merinethol 50 mg Tablet 10's interferes with the production of genetic material (DNA and RNA) in the cancer cells essential for growth, repair and multiplication of cells. Thus, Merinethol 50 mg Tablet 10's stops multiplication of abnormal cells and leads to cell's growth in an unbalanced way and causes the death of cells. 

Side Effects of Merinethol 50 mg Tablet 10's

  • Nausea
  • Vomiting
  • Low red blood cell count
  • Loss of appetite
  • Diarrhoea
  • Inflammation of the mouth

Directions for Use

Take Merinethol 50 mg Tablet 10's with or without food as advised by your doctor preferably 1 hour before or 2 hours after taking milk or dairy products. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Merinethol 50 mg Tablet 10's or any other medicines, please tell your doctor. Avoid taking Merinethol 50 mg Tablet 10's if you are pregnant or breastfeeding and consult a doctor. You are recommended to use effective contraceptive methods while using Merinethol 50 mg Tablet 10's and 3 months after completing the course of Merinethol 50 mg Tablet 10's to prevent pregnancy. Merinethol 50 mg Tablet 10's should be used with caution in children, especially in children below 6 years or with low body mass index as it may cause low blood sugar. Merinethol 50 mg Tablet 10's may increase the risk of infections. Therefore, consult your doctor if you notice any infection signs such as urinary problems, sore throat or mouth. Avoid excessive exposure to sunlight as Merinethol 50 mg Tablet 10's may cause sensitivity to sunlight. You are advised to use a sunscreen with a high protection factor and wear protective clothing while going out. Merinethol 50 mg Tablet 10's may increase the risk of a serious condition called macrophage activation syndrome (over activation of white blood cells associated with inflammation), especially in people with arthritis. If you are about to receive any vaccinations, inform your doctor that you are taking Merinethol 50 mg Tablet 10's to cause infections. 

Therapeutic Class

CHEMOTHERAPY

Drug-Drug Interactions

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MercaptopurineTalimogene laherparepvec
Critical
MercaptopurineRotavirus vaccine
Critical

Drug-Drug Interactions

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MercaptopurineTalimogene laherparepvec
Critical
How does the drug interact with Merinethol 50 mg Tablet 10's:
Co-administration of Talimogene laherparepvec with Merinethol 50 mg Tablet 10's can increase the risk or severity of side effects.

How to manage the interaction:
Taking Merinethol 50 mg Tablet 10's with Talimogene laherparepvec is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
MercaptopurineRotavirus vaccine
Critical
How does the drug interact with Merinethol 50 mg Tablet 10's:
When Rotavirus vaccine is used together with Merinethol 50 mg Tablet 10's, its effectiveness may be reduced.

How to manage the interaction:
Taking Merinethol 50 mg Tablet 10's with the Rotavirus vaccine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
MercaptopurineFebuxostat
Critical
How does the drug interact with Merinethol 50 mg Tablet 10's:
Coadministration of Merinethol 50 mg Tablet 10's with Febuxostat can increase the blood levels of Merinethol 50 mg Tablet 10's.

How to manage the interaction:
Taking Merinethol 50 mg Tablet 10's with Febuxostat is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
MercaptopurineYellow fever vaccine
Critical
How does the drug interact with Merinethol 50 mg Tablet 10's:
Co-administration of the Yellow fever vaccine with Merinethol 50 mg Tablet 10's can increase the risk of infection.

How to manage the interaction:
Taking Merinethol 50 mg Tablet 10's with the Yellow fever vaccine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
MercaptopurineBCG vaccine
Critical
How does the drug interact with Merinethol 50 mg Tablet 10's:
Co-administration of the BCG vaccine with Merinethol 50 mg Tablet 10's together can increase the risk of infection.

How to manage the interaction:
Taking Merinethol 50 mg Tablet 10's with BCG vaccine is not recommended, as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop taking any medication without consulting your doctor.
MercaptopurineClozapine
Severe
How does the drug interact with Merinethol 50 mg Tablet 10's:
Co-administration of Merinethol 50 mg Tablet 10's with Clozapine can increase the risk of neutropenia (lower white blood cell count), which may increase the risk of serious infections.

How to manage the interaction:
Although taking Merinethol 50 mg Tablet 10's and Clozapine together can cause an interaction, it can be taken if a doctor has suggested it. However, contact a doctor right away if you experience fever, chills, diarrhea, soreness, muscle aches, difficulty breathing, weight loss, or pain, burning sensation while urination. Do not stop using any medications without talking to a doctor.
MercaptopurineRibavirin
Severe
How does the drug interact with Merinethol 50 mg Tablet 10's:
Co-administration of Merinethol 50 mg Tablet 10's and Ribavirin may raise the risk of side effects. This can make you more likely to develop anemia(lack of blood), bleeding problems, or infections.

How to manage the interaction:
Although using Ribavirin and Merinethol 50 mg Tablet 10's together may cause an interaction, they can be taken together if advised by a doctor. Consult a doctor immediately if you experience any symptoms such as pale skin, tiredness, disorientation, fainting, unusual bleeding or bruises, fever, chills, sore throat and body aches. Do not stop taking any medications without consulting a doctor.
MercaptopurineCladribine
Severe
How does the drug interact with Merinethol 50 mg Tablet 10's:
Co-administration of Cladribine with Merinethol 50 mg Tablet 10's together can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and Merinethol 50 mg Tablet 10's, but it can be taken if prescribed by a doctor. If you have any of these symptoms, contact your doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not stop using any medications without a doctor's advice.
MercaptopurineAzathioprine
Severe
How does the drug interact with Merinethol 50 mg Tablet 10's:
The combined use of Azathioprine with Merinethol 50 mg Tablet 10's together can increase the risk of side effects.

How to manage the interaction:
Co-administration of Azathioprine with Merinethol 50 mg Tablet 10's can possibly result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately, if you experience any symptoms such as bruising or bleeding, fever, chills, sore throat, flu symptoms, mouth sores, black urine, severe stomach pain, jaundice (yellowing of the skin or eyes), or severe nausea, vomiting, or diarrhea. Do not stop using any medications without a doctor's advice.
MercaptopurineInfliximab
Severe
How does the drug interact with Merinethol 50 mg Tablet 10's:
Co-administration of Infliximab with Merinethol 50 mg Tablet 10's can increase the risk of infection.

How to manage the interaction:
Taking Merinethol 50 mg Tablet 10's with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, contact your doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • FEBUXOSTAT
  • ALLOPURINOL
  • MESALAZINE
  • SULFASALAZINE
  • WARFARIN
  • ACENOCOUMAROL
  • INFLIXIMAB
  • PHENYTOIN
  • CARBAMAZEPINE
  • RIBAVIRIN
  • THIOPURINOL
  • OXIPURINOL
  • OLSALAZINE

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Merinethol 50 mg Tablet 10's as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Habit Forming

No

Special Advise

  • Regular blood and urine tests are recommended while taking Merinethol 50 mg Tablet 10's to monitor the number of red blood cells, platelets, white blood cells, uric acid levels, kidney or liver functioning.
  • Do not receive any vaccination during treatment without your doctor's approval while taking Merinethol 50 mg Tablet 10's. 

Author Details

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Disease/Condition Glossary

Blood cancer: It is the cancer of blood cells, also known as leukaemia. It causes excessive production of immature white blood cells by the bone marrow. The symptoms include unintentional weight loss, weakness, excessive sweating, tiredness, bone pain, frequent infections, chills or fever, red spots on the skin or painless, swollen lymph nodes, especially in the armpits neck.  The risk factors of leukaemia include smoking, genetic or blood disorders, family history of leukaemia, exposure to high radiation levels, or previous cancer treatment with radiation or chemotherapy.

Merinethol 50 mg Tablet 10's Substitute

Substitutes safety advice
  • 6-MP Tablet 10's

    5.27per tablet
  • Admerk 50 mg Tablet 10's

    5.91per tablet
  • Puricor 50 mg Tablet 10's

    6.49per tablet
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