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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

AMOXAPINE-50MG

Manufacturer/Marketer :

Psycogen Captab

Consume Type :

ORAL

Return Policy :

Not Returnable

About A Pine 50mg Tablet

A Pine 50mg Tablet is a second-generation tricyclic dibenzoxazepine antidepressant. It is used in the treatment of depression along with anxiety and agitation. Depression is a common but serious medical condition with a low/sad mood and lack of interest in daily activities. This condition negatively affects the person's feelings, thinking and how they act. Anxiety is a mental condition characterized by excessive fear or worry affecting an individual's daily activities. This medicine is mostly given when patients become intolerant to other antidepressants.

A Pine 50mg Tablet contains Amoxapine, which is a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes. This medicine helps make your mood good and feel better.

A Pine 50mg Tablet may cause certain common side effects such as drowsiness, dry mouth, increased heart rate, constipation, dizziness, difficulty in urination, headache, fatigue, weakness, excessive appetite, restlessness, nervousness, confusion, and sudden blood pressure lowering on standing up (orthostatic hypotension). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Take A Pine 50mg Tablet as prescribed by your doctor. Your doctor will decide the dose of the medicine based on the severity of the condition.

Avoid taking A Pine 50mg Tablet if you are allergic to it or any of its ingredients. A Pine 50mg Tablet is contraindicated in patients suffering from angle closure glaucoma (increased eye pressure), severe liver or kidney problems, asthma, difficulty in urination, bipolar disorder, neuroleptic malignant syndrome, tardive dyskinesia, and if taking monoamine oxidase inhibitors (MAOs). Let your doctor know about your entire medical history beforehand. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding before starting treatment with A Pine 50mg Tablet. Do not stop taking A Pine 50mg Tablet suddenly, as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. This medicine is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

Uses of A Pine 50mg Tablet

Depression

Directions for Use

Take A Pine 50mg Tablet as advised by the doctor. It can be taken with or without food. Swallow it as a whole with a glass of water. Do not crush, chew or break the medicine.

Medicinal Benefits

A Pine 50mg Tablet contains Amoxapine which is a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes. This medicine helps make your mood good and feel better. A Pine 50mg Tablet helps treat depression when patients become intolerant to other medicines

Storage

Store in a cool and dry place away from sunlight
Side effects of A Pine 50mg Tablet
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Drug Warnings

A Pine 50mg Tablet should be avoided if you are allergic to it or any of its ingredients. A Pine 50mg Tablet is contraindicated in patients suffering from angle closure glaucoma (increased eye pressure), severe liver or kidney problems, asthma, difficulty in urination, bipolar disorder, neuroleptic malignant syndrome, tardive dyskinesia, and if taking monoamine oxidase inhibitors (MAOIs). Inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before starting treatment with A Pine 50mg Tablet. Let your doctor know if you have liver or kidney disease, asthma, seizures, Parkinson’s disease, and high blood pressure before starting treatment with this medicine, as it may cause serious side effects. It is advised not to stop taking A Pine 50mg Tablet suddenly as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. This medicine is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

Drug-Drug Interactions

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AmoxapineTranylcypromine
Critical
AmoxapineSafinamide
Critical

Drug-Drug Interactions

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AmoxapineTranylcypromine
Critical
How does the drug interact with A Pine 50mg Tablet:
Taking tranylcypromine with A Pine 50mg Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking A Pine 50mg Tablet with Tranylcypromine is not recommended, but can be taken if prescribed by a doctor. However, consult a doctor if you have symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
AmoxapineSafinamide
Critical
How does the drug interact with A Pine 50mg Tablet:
Taking Safinamide with A Pine 50mg Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with A Pine 50mg Tablet is not recommended, as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
AmoxapineZiprasidone
Critical
How does the drug interact with A Pine 50mg Tablet:
Co-administration of A Pine 50mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and A Pine 50mg Tablet but can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
AmoxapineMetoclopramide
Critical
How does the drug interact with A Pine 50mg Tablet:
Co-administration of Metoclopramide with A Pine 50mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with A Pine 50mg Tablet is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmoxapineVenlafaxine
Severe
How does the drug interact with A Pine 50mg Tablet:
When venlafaxine is combined with A Pine 50mg Tablet, can cause serotonin syndrome (a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Although taking Venlafaxine and A Pine 50mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any of the following symptoms: confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
AmoxapineVortioxetine
Severe
How does the drug interact with A Pine 50mg Tablet:
When Vortioxetine is taken with A Pine 50mg Tablet, it can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Co-administration of Vortioxetine with A Pine 50mg Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, it's a good idea to reach out to a doctor right away. Do not discontinue any medications without consulting a doctor.
AmoxapineTopiramate
Severe
How does the drug interact with A Pine 50mg Tablet:
Topiramate can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like A Pine 50mg Tablet.

How to manage the interaction:
Taking Topiramate with A Pine 50mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, or lightheadedness consult your doctor immediately. Avoid tasks that need mental attention, such as driving or operating dangerous machinery. Drink plenty of water when it's hot out and while you're exercising, and get medical assistance if you have reduced perspiration or a fever. Do not discontinue any medications without first consulting your doctor.
AmoxapineSelegiline
Severe
How does the drug interact with A Pine 50mg Tablet:
When A Pine 50mg Tablet is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between A Pine 50mg Tablet and Selegiline, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, call a doctor. Do not stop using any medications without a doctor's advice.
AmoxapineTrazodone
Severe
How does the drug interact with A Pine 50mg Tablet:
Taking Trazodone with A Pine 50mg Tablet can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Co-administration of Trazodone with A Pine 50mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience confusion, seizure(fits), extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm, tremor(shaking of hands & legs), incoordination, stomach pain, nausea, vomiting, and diarrhea contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
AmoxapineBupropion
Severe
How does the drug interact with A Pine 50mg Tablet:
Taking bupropion with A Pine 50mg Tablet may raise the chance of seizures(fits), which can happen with either medicine. Furthermore, bupropion can raise A Pine 50mg Tablet levels in the blood, which may exacerbate other adverse effects.

How to manage the interaction:
Co- administration of bupropion along with A Pine 50mg Tablet can possibly lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to do regular exercise, which can help lower anxiety and improve your sleep and self-image.
  • Find humour in your daily life. Try to watch a comedy show to help relieve stress.
  • You can try increasing your mindfulness by including yoga, meditation, cognitive therapy, and mindfulness-based stress reduction.
  • Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve anxiety.
  • Include your diet with whole grains, vegetables, and fruits which is a healthier option than eating many simple carbohydrates in processed foods.
  • Include herbs like turmeric, ginger, and chamomile in the meal. It can reduce inflammation caused due to anxiety disorder.
  • Reduce your alcohol, caffeine, added sugar, high salt, and high fat intake.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

Therapeutic Class

ANTIDEPRESSANT

A Pine 50mg Tablet Substitute

Substitutes safety advice
  • Amolox 50 Tablet 10's

    by Others

    13.50per tablet
  • Auxadep-50 Tablet 10's

    by Others

    17.10per tablet
  • Demo 50 mg Tablet 10's

    by AYUR

    5.27per tablet
  • Demolox 50mg Tablet

    by Others

    3.94per tablet
  • Axepine 50mg Tablet 10's

    by Others

    7.65per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

A Pine 50mg Tablet contains Amoxapine, which belongs to the tricyclic antidepressant class of medicine. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes.

It is always advised to take A Pine 50mg Tablet around the same time every day for better results. Do not take more than the prescribed dose.

No, it is advised not to stop taking A Pine 50mg Tablet suddenly as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. So, please consult your doctor; the doctor might lower your dose depending on your medical condition.

Drug-Drug Interactions Checker List

  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • CHLORPROMAZINE
  • FLUPHENAZINE
  • TRIFLUOPERAZINE
  • BUPROPION
  • CIMETIDINE
  • TOLAZAMIDE
  • CODEINE
  • ALPRAZOLAM
  • ZOLPIDEM

Special Advise

  • Regular blood tests are required to monitor blood sugar and sodium level.
  • Regular blood tests for monitoring various kinds of blood cells.
  • Family members should monitor the patient for suicidal thoughts, unusual or withdrawal symptoms while taking A Pine 50mg Tablet.

Disease/Condition Glossary

Depression: Depression is a common but serious medical condition with a low/sad mood and lack of interest in daily activities. This condition negatively affects the persons feeling, thinking and how they act.  The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drug use, and medical conditions. It can influence some chronic health conditions and relationships. This condition is characterized by sadness, unhappiness, anger, hopelessness, etc.

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