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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Axepine 50mg Tablet 10's

Axepine 50mg Tablet 10's is a second-generation tricyclic dibenzoxazepine antidepressant. It is used in the treatment of depression along with anxiety and agitation. Depression is a common but serious medical condition with a low/sad mood and lack of interest in daily activities. This condition negatively affects the person's feelings, thinking and how they act. Anxiety is a mental condition characterized by excessive fear or worry affecting an individual's daily activities. This medicine is mostly given when patients become intolerant to other antidepressants.

Axepine 50mg Tablet 10's contains Amoxapine, which is a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes. This medicine helps make your mood good and feel better.

Axepine 50mg Tablet 10's may cause certain common side effects such as drowsiness, dry mouth, increased heart rate, constipation, dizziness, difficulty in urination, headache, fatigue, weakness, excessive appetite, restlessness, nervousness, confusion, and sudden blood pressure lowering on standing up (orthostatic hypotension). Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Take Axepine 50mg Tablet 10's as prescribed by your doctor. Your doctor will decide the dose of the medicine based on the severity of the condition.

Avoid taking Axepine 50mg Tablet 10's if you are allergic to it or any of its ingredients. Axepine 50mg Tablet 10's is contraindicated in patients suffering from angle closure glaucoma (increased eye pressure), severe liver or kidney problems, asthma, difficulty in urination, bipolar disorder, neuroleptic malignant syndrome, tardive dyskinesia, and if taking monoamine oxidase inhibitors (MAOs). Let your doctor know about your entire medical history beforehand. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding before starting treatment with Axepine 50mg Tablet 10's. Do not stop taking Axepine 50mg Tablet 10's suddenly, as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. This medicine is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

AMOXAPINE-50MG

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Axepine 50mg Tablet 10's

Depression

Medicinal Benefits

Axepine 50mg Tablet 10's contains Amoxapine which is a second-generation tricyclic dibenzoxazepine antidepressant. It works by increasing the level of certain chemicals (GABA) in the brain that are responsible for your mental health and mood changes. This medicine helps make your mood good and feel better. Axepine 50mg Tablet 10's helps treat depression when patients become intolerant to other medicines

Side Effects of Axepine 50mg Tablet 10's

  • Drowsiness
  • Dry mouth
  • Increased heart rate
  • Constipation
  • Difficulty in urination
  • Dizziness
  • Headache
  • Fatigue
  • Weakness
  • Excessive appetite
  • Restlessness
  • Nervousness
  • Confusion
  • Orthostatic hypotension (Sudden lowering of blood pressure on standing up)

Directions for Use

Take Axepine 50mg Tablet 10's as advised by the doctor. It can be taken with or without food. Swallow it as a whole with a glass of water. Do not crush, chew or break the medicine.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Axepine 50mg Tablet 10's should be avoided if you are allergic to it or any of its ingredients. Axepine 50mg Tablet 10's is contraindicated in patients suffering from angle closure glaucoma (increased eye pressure), severe liver or kidney problems, asthma, difficulty in urination, bipolar disorder, neuroleptic malignant syndrome, tardive dyskinesia, and if taking monoamine oxidase inhibitors (MAOIs). Inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before starting treatment with Axepine 50mg Tablet 10's. Let your doctor know if you have liver or kidney disease, asthma, seizures, Parkinson’s disease, and high blood pressure before starting treatment with this medicine, as it may cause serious side effects. It is advised not to stop taking Axepine 50mg Tablet 10's suddenly as it can cause withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. This medicine is not recommended for use in children below 16 years of age as the safety and efficacy are not established.

Therapeutic Class

ANTIDEPRESSANT

Drug-Drug Interactions

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AmoxapineMetoclopramide
Critical
AmoxapineTranylcypromine
Critical

Drug-Drug Interactions

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AmoxapineMetoclopramide
Critical
How does the drug interact with Axepine 50mg Tablet 10's:
Co-administration of Metoclopramide with Axepine 50mg Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Axepine 50mg Tablet 10's is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmoxapineTranylcypromine
Critical
How does the drug interact with Axepine 50mg Tablet 10's:
Taking tranylcypromine with Axepine 50mg Tablet 10's can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Axepine 50mg Tablet 10's with Tranylcypromine is not recommended, but can be taken if prescribed by a doctor. However, consult a doctor if you have symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
AmoxapineZiprasidone
Critical
How does the drug interact with Axepine 50mg Tablet 10's:
Co-administration of Axepine 50mg Tablet 10's with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Axepine 50mg Tablet 10's but can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
AmoxapineSafinamide
Critical
How does the drug interact with Axepine 50mg Tablet 10's:
Taking Safinamide with Axepine 50mg Tablet 10's can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Axepine 50mg Tablet 10's is not recommended, as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
AmoxapineMoxifloxacin
Severe
How does the drug interact with Axepine 50mg Tablet 10's:
Using Moxifloxacin together with Axepine 50mg Tablet 10's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Moxifloxacin with Axepine 50mg Tablet 10's can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, irregular heart rhythm, or difficulty breathing, it is important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
AmoxapineClonidine
Severe
How does the drug interact with Axepine 50mg Tablet 10's:
Co-administration of Clonidine and Axepine 50mg Tablet 10's may increase the risk and severity of increased side effects.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Axepine 50mg Tablet 10's, you can take these medicines together if prescribed by a doctor. However, contact a doctor if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache, or heart palpitations. Do not discontinue the medication without consulting a doctor.
AmoxapineBupropion
Severe
How does the drug interact with Axepine 50mg Tablet 10's:
Taking bupropion with Axepine 50mg Tablet 10's may raise the chance of seizures(fits), which can happen with either medicine. Furthermore, bupropion can raise Axepine 50mg Tablet 10's levels in the blood, which may exacerbate other adverse effects.

How to manage the interaction:
Co- administration of bupropion along with Axepine 50mg Tablet 10's can possibly lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.
AmoxapineSotalol
Severe
How does the drug interact with Axepine 50mg Tablet 10's:
Using Sotalol together with Axepine 50mg Tablet 10's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Sotalol with Axepine 50mg Tablet 10's can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations Do not stop using any medications without consulting a doctor.
AmoxapineSelegiline
Severe
How does the drug interact with Axepine 50mg Tablet 10's:
When Axepine 50mg Tablet 10's is taken with Selegiline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Axepine 50mg Tablet 10's and Selegiline, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, call a doctor. Do not stop using any medications without a doctor's advice.
AmoxapineSertraline
Severe
How does the drug interact with Axepine 50mg Tablet 10's:
Co-administration of Axepine 50mg Tablet 10's and Sertraline together may increase the effects of Axepine 50mg Tablet 10's.

How to manage the interaction:
Although there is a possible interaction between Sertraline and Axepine 50mg Tablet 10's, they can be taken together if a doctor has prescribed it. Contact a doctor immediately if experience such as dry mouth, blurred vision, constipation, confusion, poor muscle coordination, abdominal cramping, shivering, sweating, and high heart rate. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • CHLORPROMAZINE
  • FLUPHENAZINE
  • TRIFLUOPERAZINE
  • BUPROPION
  • CIMETIDINE
  • TOLAZAMIDE
  • CODEINE
  • ALPRAZOLAM
  • ZOLPIDEM

Diet & Lifestyle Advise

  • Try to do regular exercise, which can help lower anxiety and improve your sleep and self-image.
  • Find humour in your daily life. Try to watch a comedy show to help relieve stress.
  • You can try increasing your mindfulness by including yoga, meditation, cognitive therapy, and mindfulness-based stress reduction.
  • Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve anxiety.
  • Include your diet with whole grains, vegetables, and fruits which is a healthier option than eating many simple carbohydrates in processed foods.
  • Include herbs like turmeric, ginger, and chamomile in the meal. It can reduce inflammation caused due to anxiety disorder.
  • Reduce your alcohol, caffeine, added sugar, high salt, and high fat intake.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

Special Advise

  • Regular blood tests are required to monitor blood sugar and sodium level.
  • Regular blood tests for monitoring various kinds of blood cells.
  • Family members should monitor the patient for suicidal thoughts, unusual or withdrawal symptoms while taking Axepine 50mg Tablet 10's.

Disease/Condition Glossary

Depression: Depression is a common but serious medical condition with a low/sad mood and lack of interest in daily activities. This condition negatively affects the persons feeling, thinking and how they act.  The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drug use, and medical conditions. It can influence some chronic health conditions and relationships. This condition is characterized by sadness, unhappiness, anger, hopelessness, etc.

Axepine 50mg Tablet 10's Substitute

Substitutes safety advice
  • Amolox 50 Tablet 10's

    13.50per tablet
  • Auxadep-50 Tablet 10's

    17.10per tablet
  • Demo 50 mg Tablet 10's

    by AYUR

    5.27per tablet
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