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  3. Acalnib 100 mg Capsule 30's

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Whats That

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Composition :

ACALABRUTINIB-100MG

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

About Acalnib 100 mg Capsule 30's

Acalnib 100 mg Capsule 30's is a tyrosine kinase inhibitor or cancer growth inhibitor that is primarily used to treat people with mantle cell lymphoma (MCL) who have had at least one prior treatment for their malignancy (cancer), as well as adults with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL). Cancer is caused by a genetic mutation that causes our cells to divide uncontrollably and spread into neighbouring tissues.

Acalnib 100 mg Capsule 30's contains Acalabrutinib, a tyrosine kinase inhibitor. Tyrosine kinases are enzymes in the body that transmit signals to cells, telling them to grow and divide. Acalabrutinib inhibits these signals to cancer cells. Cells die when their signals are disrupted. This could help to slow the progression of the cancer.

To treat your condition effectually, continue using Acalnib 100 mg Capsule 30's for as long as your doctor has prescribed it. The most common adverse reactions are anaemia (lack of blood), neutropenia (low count of neutrophils), upper respiratory tract infection, thrombocytopenia (Low platelet level), headache, diarrhoea, and musculoskeletal pain. You should talk to your doctor if you persistently experience these side effects.

It is recommended not to use if you are hypersensitive to any component present in Acalnib 100 mg Capsule 30's and suffer from Severe Hepatic Impairment. Acalnib 100 mg Capsule 30's can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months after the treatment. Using effective contraceptive methods is recommended while on therapy with Acalnib 100 mg Capsule 30's. Contact your doctor immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.

Uses of Acalnib 100 mg Capsule 30's

Mantle cell lymphoma (MCL), chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL)

Directions for Use

Acalnib 100 mg Capsule 30's should be swallowed as a whole with a glass of water. Do not crush, chew, or break the tablets. The doctor determines the dose and duration based on your health condition.

Key Benefits

Acalnib 100 mg Capsule 30's is primarily used to treat people with mantle cell lymphoma (MCL) who have had at least one prior treatment for their malignancy, as well as adults with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL). Acalnib 100 mg Capsule 30's contains Acalabrutinib, a tyrosine kinase inhibitor. Tyrosine kinases are enzymes in the body that send signals to cells, directing them to grow and divide. Acalabrutinib blocks these signals to cancer cells. Cancer cells die when their signals are interrupted. This could help to delay the progression of the cancer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking the Acalnib 100 mg Capsule 30's, inform your doctor about all your medical conditions, sensitivities, and medications you are using. If you are a woman capable of having children, you should use an effective method of contraception during Acalabrutinib treatment and for at least one week after the last dose. If you are a man, you should use a barrier method of contraception to prevent your partner from becoming pregnant while taking Acalabrutinib and for at least one week after the last dose. Unless the doctor suggests, do not use any other medicine, including herbal or vitamin supplements.

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs, and added sugars.

Side Effects of Acalnib 100 mg Capsule 30's

  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Fatigue (
  • Anaemia (lack of blood)
  • Neutropenia (low count of neutrophils)
  • Upper respiratory tract infection
  • Thrombocytopenia (low platelet level)
  • Headache
  • Diarrhea
  • Musculoskeletal pain (myalgia)
  • Abdominal pain
  • Fatigue (tiredness)
  • Bruising
  • Rash
  • Haemorrhage (bleeding)
  • Epistaxis (nosebleed)

Habit Forming

No

Therapeutic Class

[KINASE INHIBITORS]

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FAQs

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Special Advise

  • Keep all of your doctor's and laboratory appointments.
  • Pregnancy testing is recommended prior to starting treatment with Acalnib 100 mg Capsule 30's.

Disease/Condition Glossary

Cancer: Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Types of cancer include blood, lung, breast, etc. Cancer growth can be prevented by chemotherapy, radiation, and stem cell therapy.

Mantle Cell lymphoma (MCL): Mantle Cell lymphoma (MCL) is an aggressive, rare form of non-Hodgkin lymphoma (NHL) that arises from cells originating in the “mantle zone.” The mantle zone is the outer ring of small lymphocytes surrounding the centre of a lymphatic nodule.

Have a query?

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Alcohol

Safe if prescribed

Avoid alcohol consumption while on treatment with Acalnib 100 mg Capsule 30's.

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Pregnancy

Consult your doctor

Acalnib 100 mg Capsule 30's should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Consult your doctor

Acalnib 100 mg Capsule 30's should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

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Driving

Safe if prescribed

Acalnib 100 mg Capsule 30's does not influence the ability to drive or use machines. However, go only if you are alert, as the Acalnib 100 mg Capsule 30's may cause tiredness in some people.

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Liver

Consult your doctor

Avoid using Acalnib 100 mg Capsule 30's in patients with severe hepatic impairment. The safety of Acalnib 100 mg Capsule 30's has not been evaluated in patients with moderate or severe hepatic impairment. So, caution should be exercised while using Acalnib 100 mg Capsule 30's in patients with liver impairment. If you have a pre-existing or a history of liver disease, inform your doctor before taking the Acalnib 100 mg Capsule 30's. Your doctor will weigh the benefits and potential risks before prescribing Acalnib 100 mg Capsule 30's.

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Kidney

Consult your doctor

Caution should be exercised while using Acalnib 100 mg Capsule 30's in patients with kidney impairment. If you have a pre-existing or a history of kidney disease, inform your doctor before taking the Acalnib 100 mg Capsule 30's. Your doctor will weigh the benefits and potential risks before prescribing Acalnib 100 mg Capsule 30's.

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Children

Safe if prescribed

Safety and effectiveness in patients below the age of 18 years have not been established. Hence, use is not recommended.

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Heart

Take Acalnib 100 mg Capsule 30's with caution, especially if you have a history of heart diseases/conditions. The dose may be adjusted by your doctor as required.

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Geriatrics

Consult your doctor

Acalnib 100 mg Capsule 30's can be safely used in elderly patients with proper monitoring and individualised care.

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