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Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Acron Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

About Acrogyl DF 400mg/500mg Tablet

Acrogyl DF 400mg/500mg Tablet belongs to a group of medicines known as antibiotics used to treat various infections caused by bacteria and parasites (amoeba). It is prescribed for the treatment of diarrhea caused by microorganisms Clostridium difficile, Entamoeba histolytica and Giardia lamblia. Additionally, it also treats vaginal and other bacterial infections. Infections caused by amoeba usually happen due to drinking contaminated water or eating food that contains contaminated water. Diarrhea is defined as loose, watery stools or frequent movement of the bowel.

Acrogyl DF 400mg/500mg Tablet contains two medicines namely: Metronidazole and Diloxanide. Acrogyl DF 400mg/500mg Tablet contains Metronidazole which is an antibiotic , it treats the infection by damaging the DNA of the organism and does killing the bacteria. Diloxanide is an amoebicide. It works inside the large intestine to kill the infection causing amoeba (parasites). Altogether Acrogyl DF 400mg/500mg Tablet kills the bacteria and parasites. Acrogyl DF 400mg/500mg Tablet does not treat a viral infection like flu or a common cold.

Take Acrogyl DF 400mg/500mg Tablet as prescribed by your doctor. You are advised to take Acrogyl DF 400mg/500mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. Some common side effects of Acrogyl DF 400mg/500mg Tablet are nausea, vomiting, upset stomach, loss of appetite, dry mouth and metallic taste. If these effects appear and are bothersome, call your doctor or pharmacist.

Use of Acrogyl DF 400mg/500mg Tablet is contraindicated in the patient suffering from central nervous system (CNS) diseases like seizures (fits). Acrogyl DF 400mg/500mg Tablet should not be used during pregnancy, especially during the first trimester. So, let your doctor know if you are pregnant or planning to get pregnant. You should not breastfeed while taking Acrogyl DF 400mg/500mg Tablet as it passes into the breastmilk, and can affect the baby. Do not drive or operate heavy machinery after taking Acrogyl DF 400mg/500mg Tablet as it may cause dizziness, drowsiness and make you less alert.

Uses of Acrogyl DF 400mg/500mg Tablet

Bacterial Infections, Diahorrea due to Entamoeba histolytica, Giardia lamblia or Clostridium difficile, Vaginal bacterial infections, Dental infections, Post-surgery infections, Skin bacterial infections.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Syrup/suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Acrogyl DF 400mg/500mg Tablet is a broad-spectrum antibiotic that is effective against a wide range of gram-positive and gram-negative bacteria. kills the harmful bacteria and amoeba (Entamoeba histolytica, Giardia lamblia, Clostridium difficile) causing diarrhoea. Acrogyl DF 400mg/500mg Tablet contains Metronidazole which is an antibiotic , it treats the infection by damaging the DNA of the organism and does killing the bacteria. Diloxanide is an amoebicide. It works inside the large intestine to kill the infection causing amoeba (parasites). Altogether Acrogyl DF 400mg/500mg Tablet kills the bacteria and parasites. Acrogyl DF 400mg/500mg Tablet does not treat a viral infection like flu or a common cold.

Storage

Keep Acrogyl DF 400mg/500mg Tablet out of the sight and reach of children.
Side effects of Acrogyl DF 400mg/500mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Inflammation of Vagina needs immediate attention and cannot be ignored.
  • Get a physical examination and prevent wearing clothes that can hold heat and moisture.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Follow your doctor's instructions, and rest well with proper medication.
  • Take a balanced diet and get regular screenings to reduce inflammation.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.

Drug Warnings

You should immediately report to the doctor in case you have symptoms of dehydration like dehydration dry mouth, excessive thirst, wrinkled skin, little or no urination, dizziness and lightheadedness. In some cases, prolonged intake of Acrogyl DF 400mg/500mg Tablet has been associated with leukopenia (low count of white blood cells). Intake of probiotics, prebiotics and plenty of fluids is recommended if you are suffering from dysentery and diarrhea. If you are feeling sick or vomiting, then it is advised to eat simple foods or avoid spicy foods. If a person experiences skin rash or itching after taking Acrogyl DF 400mg/500mg Tablet then they should consult with their doctor.

Drug-Drug Interactions

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MetronidazoleAmprenavir
Critical

Drug-Drug Interactions

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How does the drug interact with Acrogyl DF 400mg/500mg Tablet:
Coadministration of Disulfiram with Acrogyl DF 400mg/500mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Acrogyl DF 400mg/500mg Tablet and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
MetronidazoleAmprenavir
Critical
How does the drug interact with Acrogyl DF 400mg/500mg Tablet:
Co-administration of Amprenavir with Acrogyl DF 400mg/500mg Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Acrogyl DF 400mg/500mg Tablet with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Acrogyl DF 400mg/500mg Tablet:
Drinking alcohol while taking Acrogyl DF 400mg/500mg Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Acrogyl DF 400mg/500mg Tablet with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Acrogyl DF 400mg/500mg Tablet:
Coadministration of Acrogyl DF 400mg/500mg Tablet with warfarin can increase the risk of bleeding.

How to manage the interaction:
There is a possible interaction between Acrogyl DF 400mg/500mg Tablet and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Acrogyl DF 400mg/500mg Tablet:
Coadministration of Busulfan and Acrogyl DF 400mg/500mg Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Acrogyl DF 400mg/500mg Tablet and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
How does the drug interact with Acrogyl DF 400mg/500mg Tablet:
Coadministration of Acrogyl DF 400mg/500mg Tablet with mebendazole may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Acrogyl DF 400mg/500mg Tablet and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Acrogyl DF 400mg/500mg Tablet:
Co-administration of Fluconazole together with Acrogyl DF 400mg/500mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
-Taking Acrogyl DF 400mg/500mg Tablet with Fluconazole together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • If you have diarrhea try to drink appropriate amounts of fluids to avoid dehydration. 
  • If you have minor diarrhea (less than four stools daily) drinking caffeine-free soft drinks, juices or sport rehydration drinks can be sufficient. 
  • If the diarrhea is more severe, specially formulated rehydration drinks should be taken. Consult your doctor immediately.

Side Effects of Acrogyl DF 400mg/500mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Upset stomach
  • Loss of appetite
  • Constipation
  • Headache
  • Dizziness
  • Skin rash
  • Dry mouth
  • Sharp, unpleasant metallic taste

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Acrogyl DF 400mg/500mg Tablet is an antibiotic medication so it is advised to complete the full course even if you start to feel better to prevent the return of the infection.

Yes, it could be due to jaundice as in rare cases Acrogyl DF 400mg/500mg Tablet can lead to it. Please consult your doctor immediately if the yellowing of the skin persists and does not subside.

You should complete the full course of Acrogyl DF 400mg/500mg Tablet as prescribed by your doctor. After completing the full course of Acrogyl DF 400mg/500mg Tablet will work. You must take Acrogyl DF 400mg/500mg Tablet at the right dose, right times and for the right numbers of days.

Acrogyl DF 400mg/500mg Tablet is an antibacterial medicine that acts only against bacterial infections and not viral infections like common cold and flu. You should not take Acrogyl DF 400mg/500mg Tablet without prior consulting your doctor. Self-medication is dangerous and can lower the efficacy of Acrogyl DF 400mg/500mg Tablet, leading to antibiotic resistance.

If you miss a dose of Acrogyl DF 400mg/500mg Tablet, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

Drug-Drug Interactions Checker List

  • FLUOROURACIL
  • CIMETIDINE
  • PHENOBARBITAL
  • DISULFIRAM
  • BUSULFAN

Special Advise

  • Please consult your doctor immediately if have allergic reactions like skin rash, which may be itchy, swelling of the face, lips, tongue or throat, fever or difficulty in breathing.
  • Don't stop taking the tablets your infection may come back, Talk to your doctor before you stop taking the tablets and follow their advice.

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills and fatigue. Bacteria are of various forms comprising commonly of spherical, rod and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.
Amoebic dysentery: It is an intestinal (bowel) illness caused by a parasite (amoeba) known as Entamoeba histolytica spread through human feces (poop). Usually, there are no symptoms, but sometimes it causes diarrhoea (loose stool/poop), nausea (a feeling of sickness in the stomach) and weight loss.

Have a query?

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Acrogyl DF 400mg/500mg Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

Acrogyl DF 400mg/500mg Tablet should not be used during pregnancy, especially during the first trimester.

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Breast Feeding

Caution

Take Acrogyl DF 400mg/500mg Tablet only when prescribed, it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Caution

Acrogyl DF 400mg/500mg Tablet may affect driving as it causes dizziness, so it is advised to avoid driving.

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Liver

Caution

Acrogyl DF 400mg/500mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Acrogyl DF 400mg/500mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Dose to be adjusted and recommended by a child specialist only.

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