Mebendazole
About
Mebendazole belongs to a group of antiparasitic drugs called 'anthelmintic' used to treat parasite worm infections like pinworm, whipworm, roundworm, hookworm, and other parasites. Parasitic worms are also called intestinal worms or helminths. They live in and feed on the hosts leading to weakness and diseases. Common types of intestinal worms are roundworms and flatworms such as tapeworms and flukes.
Mebendazole contains ‘Mebendazole’, which works by inhibiting tubulin polymerization. This causes metabolic disruption and energy depletion in the parasite, which leads to its immobilization. Thereby, Mebendazole kills the susceptible helminth and treats the infection.
Take Mebendazole as prescribed. You are advised to take Mebendazole for as long as your doctor has prescribed it for you, depending on your medical condition. You may experience certain common side-effects such as abdominal pain, diarrhoea, not being hungry, gas, and upset stomach. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Mebendazole might increase the chances of getting an infection; maintain proper hygiene, and try to stay away from people with infections, flu or cold. Consult your doctor if you notice unusual bleeding or bruising as you may bleed or bruise easily while taking Mebendazole. Do not take Mebendazole if you have any allergies, liver problems, and intestinal problems. Inform your doctor before taking Mebendazole if you are pregnant or planning for pregnancy, as it may cause fetal harm. If you are a breastfeeding mother, immediately contact your doctor because Mebendazole passes into breast milk.
Uses of Mebendazole
Medicinal Benefits
Mebendazole belongs to a group of anthelmintic medicines used to treat worm infections such as pinworm, whipworm, roundworm, hookworm, and other parasites. Mebendazole contains ‘Mebendazole’, which works by inhibiting tubulin polymerization. This causes metabolic disruption and energy depletion in the parasite, which leads to its immobilization. Thereby, Mebendazole kills the susceptible helminth and treats the infection.
Directions for Use
Storage
Side Effects of Mebendazole
- Abdominal pain
- Diarrhoea
- Not hungry
- Gas
- Upset stomach
In-Depth Precautions and Warning
Drug Warnings
Mebendazole might increase the chances of getting an infection; maintain proper hygiene, and try to stay away from people with infections, flu, or cold. Consult your doctor if you notice unusual bleeding or bruising as you may bleed or bruise easily while taking Mebendazole. Do not take Mebendazole if you have any allergies, liver problems, and intestinal problems. Inform your doctor before taking Mebendazole if you are pregnant or planning for pregnancy, as it may cause fetal harm. If you are a breastfeeding mother, immediately contact your doctor because Mebendazole passes into breast milk. Mebendazole can be given to children above 2 years if prescribed by the doctor.
Drug Interactions
Drug-Drug Interactions: Mebendazole may have interaction with antacid (cimetidine), a drug used to treat epilepsy (carbamazepine), antibiotics (metronidazole), and antivirals (ritonavir).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Mebendazole may have interactions with liver disease.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafePlease do not drink alcohol with this Mebendazole because it may produce drowsiness as a side effect.
Pregnancy
unsafeMebendazole belongs to pregnancy category C. Do not take Mebendazole if you are pregnant or planning for pregnancy as it may cause fetal harm. Please consult your doctor if you have any concerns regarding this.
Breast Feeding
unsafeMebendazole may pass into breast milk that may cause harm to the baby. Please consult your doctor if you have any concerns regarding this.
Driving
cautionIf you experience drowsiness, hypotension, dizziness, or a headache as side-effects when using Mebendazole then it may not be safe to drive or operate heavy machinery.
Liver
unsafeDose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
cautionDose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
safe if prescribedMebendazole can be given to children above 2 years if prescribed by the doctor.
Habit Forming
Diet & Lifestyle Advise
- Regularly wash your hands with soap and water, especially after using the toilet and while eating.
- Avoid eating raw fish and meat.
- Thoroughly cook meat before eating.
- Wash all fruits and vegetables properly before consuming them.
- Wash or reheat food that has been around for a long time.
- Avoid contact with soil that may be contaminated with faeces.
- Avoid foods that have been kept open in the markets as they can be contaminated.
- Drink boiled and purified water.
Special Advise
- Regular monitoring of blood cell count and liver function is advised during treatment with Mebendazole.
- Mebendazole might increase the chances of getting an infection; maintain proper hygiene, and try to stay away from people with infections, flu, or cold.
- Consult your doctor if you notice unusual bleeding or bruising as you may bleed or bruise easily while taking Mebendazole.
- Mebendazole will not treat a viral infection such as the flu or a common cold.
- Mebendazole can increase the risk of bleeding and infection, so frequent medical tests are required.
- While taking Mebendazole close monitoring of liver function is required for every 2 weeks.
Patients Concern
Disease/Condition Glossary
Parasitic worm infections: Parasitic worms are also called intestinal worms or helminths. They live in and feed on the hosts leading to weakness and diseases. Common types of intestinal worms are roundworms and flatworms such as tapeworms and flukes. Worm infections could occur due to consumption of contaminated water, food or soil, contact with contaminated faeces, poor sanitization, and poor hygiene. Symptoms of worm infections include abdominal pain, diarrhoea, nausea, vomiting, gas, bloating, fatigue, unexplained weight loss, and dysentery (bloody stools).
FAQs
Mebendazole causes metabolic disruption and energy depletion in the parasite, which leads to its immobilization. Thereby, Mebendazole kills the susceptible helminth and treats the infection.
Regular monitoring of blood count at the beginning of each cycle therapy and for every 2weeks while taking Mebendazole is advised for all patients. Treatment with Mebendazole should be discontinued if a significant decrease in blood cell count is observed.
Mebendazole might increase the chances of getting an infection. Maintain proper hygiene and try to stay away from people with infections, flu or cold.
Do not discontinue Mebendazole without consulting your doctor. To treat your condition effectually continue taking Mebendazole for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Mebendazole.
Take the missed dose of Mebendazole as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.
