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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Aretaeus Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Adgril A Tablet

Adgril A Tablet belongs to the class of antiplatelet drugs used for the prevention of heart attack and stroke. A heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is most often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). Signs of a heart attack include chest pain, upper body pain, sweating, nausea, fatigue and trouble breathing.

Adgril A Tablet is composed of two medicines, namely: Aspirin and Clopidogrel. These are blood thinners (anti-platelet) that prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels). Adgril A Tablet helps in the free flow of blood, thereby preventing a heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of lungs).

Your doctor will advise you on how often you take your tablets based on your medical condition. The common side effects of Adgril A Tablet include abdominal pain, indigestion, diarrhoea, easy bruising, and nosebleeds. Adgril A Tablet is known to cause dizziness and blurry vision, so driving should be avoided. Most of these side effects of Adgril A Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Stopping Adgril A Tablet may worsen your condition and increase the risk of a future heart attack. Let your doctor know if are sensitive to clopidogrel or aspirin, have kidney/liver diseases, bleeding issues (like peptic ulcer, brain haemorrhage), pregnant or planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Adgril A Tablet before any surgery is scheduled or any new medicine is taken. 

Uses of Adgril A Tablet

Prevention of heart attack and stroke.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Adgril A Tablet is composed of Aspirin and Clopidogrel, which act as blood thinners (anti-platelet) and prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels). Adgril A Tablet helps in the free flow of blood, thereby preventing heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of lungs).

Storage

Keep out of the sight and reach of children.
Side effects of Adgril A Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Drug Warnings

You should avoid taking Adgril A Tablet if you are allergic to Adgril A Tablet . Let your doctor know if you have a medical condition that is causing bleeding such as a haemophilia, stomach ulcer or bleeding within your head or bowel. Caution is required before giving Adgril A Tablet to the liver or kidney problems patients. People affected with respiratory problems like asthma, rhinitis or nasal polyps should consult a doctor before intake of Adgril A Tablet . Adgril A Tablet is not recommended for the breastfeeding mother as it passes into the breast milk. The safety and effectiveness of Adgril A Tablet in children less than 12 years of age have not been established. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Adgril A Tablet:
When Selexipag and Adgril A Tablet are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Adgril A Tablet with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
How does the drug interact with Adgril A Tablet:
Taking Adgril A Tablet together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Adgril A Tablet with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Adgril A Tablet:
Co-administration of Ketorolac and Adgril A Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Adgril A Tablet is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Adgril A Tablet:
Combining Ketorolac tromethamine with Adgril A Tablet can increase the risk of adverse effects.

How to manage the interaction:
Taking Adgril A Tablet with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
How does the drug interact with Adgril A Tablet:
Taking Adgril A Tablet with ticlopidine can reduced effectiveness of Adgril A Tablet.

How to manage the interaction:
Taking Adgril A Tablet and Ticlopidine together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.
ClopidogrelPonatinib
Severe
How does the drug interact with Adgril A Tablet:
Using ponatinib together with Adgril A Tablet may increase the risk of bleeding

How to manage the interaction:
Although taking Adgril A Tablet and Ponatinib together can cause an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor immediately if you experience bleeding, dizziness, or black stools. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Adgril A Tablet:
Taking Adgril A Tablet together with Panobinostat can increases the risk of bleeding.

How to manage the interaction:
Although taking Adgril A Tablet together with panobinostat can result in interaction, it can be taken if prescribed by a doctor. However, consult your doctor immediately if you experience dizziness, lightheadedness, redness or blackness, sticky stools, or severe headache. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Adgril A Tablet:
Adgril A Tablet increases the blood levels of Repaglinide, which results in increased effectiveness of Repaglinide. When these medicines are taken together, you may experience low blood sugar (hypoglycemia).

How to manage the interaction:
Although taking Adgril A Tablet with Repaglinide may result in interaction, it can be taken if prescribed by a doctor. However, if you experience any signs of hypoglycemia (low blood sugar), consult your doctor immediately. Common symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, weakness, tremor, nausea, hunger, sweating, and palpitation. It is advised to monitor your blood sugar levels if you experience the above symptoms. Do not discontinue any medication without consulting a doctor.
ClopidogrelDefibrotide
Severe
How does the drug interact with Adgril A Tablet:
Taking Adgril A Tablet with Defibrotide can increase the risk of bleeding.

How to manage the interaction:
Although taking Adgril A Tablet and Defibrotide together can cause an interaction, it can be taken if your doctor has suggested it. However, consult a doctor if you experience bleeding, bruising, feeling dizzy or lightheaded, having black or tarry stools, experiencing a severe headache, feeling weak, or having bleeding or vomiting. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Adgril A Tablet:
Taking Adgril A Tablet together with Prasugrel will have an additive effect and increase the risk of bleeding.

How to manage the interaction:
Although taking Adgril A Tablet together with Prasugrel may result in interaction, it can be taken if prescribed by a doctor. However, If you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, or having a severe headache, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Adgril A Tablet .
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, and vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Side Effects of Adgril A Tablet

  • Abdominal pain
  • Indigestion
  • Diarrhoea
  • Easy bruising
  • Nosebleeds
  • Increased bleeding tendency

Habit Forming

No

Therapeutic Class

PLATELET AGGREGATION INHIBITOR

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Adgril A Tablet consists Aspirin and Clopidogrel. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels).

Please consult your doctor if Adgril A Tablet needs to be discontinued before undergoing surgery. The doctor might ask you to stop taking Adgril A Tablet a few days before surgery since it can cause an increased risk of bleeding during surgery.

Adgril A Tablet consists of Aspirin and Clopidogrel. These are blood-thinning agents and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

Adgril A Tablet is generally safe to take for a long time. It works best if you take it for many months or even years. If you're at risk of getting a stomach ulcer, your doctor may prescribe a medicine to treat ulcer, while you're taking Adgril A Tablet .

Drug-Drug Interactions Checker List

  • WARFARIN
  • HEPARIN
  • FLUOXETINE
  • LITHIUM
  • GLIBENCLAMIDE
  • REPAGLINIDE
  • METHOTREXATE
  • VALPROATE
  • PHENYTOIN
  • IBUPROFEN
  • OMEPRAZOLE
  • FLUCONAZOLE
  • RITONAVIR
  • COBICISTAT
  • PROBENECID

Special Advise

Let your doctor know that you are using Adgril A Tablet if you have a scheduled surgery since this medicine may increase the risk of bleeding.

Disease/Condition Glossary

A blood clot is a clump or aggregation of blood that changes from a liquid to a gel-like state. Clotting is a natural process that prevents you from losing too much blood in an accident, trauma, surgery or cut. When a clot forms inside the veins, it won’t always dissolve on its own and can become even life-threatening situation.

Stroke: When our brain does not get sufficient oxygen and blood supply, it starts dying within a few minutes leading to a heart attack or stroke.

Heart attack: It occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is most often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). During a heart attack (myocardial infarction), the blood supply which nourishes the heart with oxygen is cut off. This causes the heart muscle to die. Signs of a heart attack include chest pain, upper body pain, sweating, nausea, fatigue and trouble breathing.

Have a query?

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Alcohol

Caution

Avoid consuming alcohol since it may worsen the side effects like dizziness and increased blood pressure.

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Pregnancy

Caution

Adgril A Tablet is not recommended to use during pregnancy since it may affect the foetus. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Adgril A Tablet .

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Breast Feeding

Caution

There is limited data on how Adgril A Tablet affects breastfeeding. Please consult your doctor before starting Adgril A Tablet .

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Adgril A Tablet . Adgril A Tablet can also sometimes cause blurry vision, hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Adgril A Tablet .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Adgril A Tablet .

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Children

Caution

Adgril A Tablet is not recommended for children below the age of 16 years. The safety and efficacy of Adgril A Tablet have not been established in children.

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