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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Clodrel Plus Tablet

Clodrel Plus Tablet belongs to the class of antiplatelet drugs used for the prevention of heart attack and stroke. A heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is most often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). Signs of a heart attack include chest pain, upper body pain, sweating, nausea, fatigue and trouble breathing.

Clodrel Plus Tablet is composed of two medicines, namely: Aspirin and Clopidogrel. These are blood thinners (anti-platelet) that prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels). Clodrel Plus Tablet helps in the free flow of blood, thereby preventing a heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of lungs).

Your doctor will advise you on how often you take your tablets based on your medical condition. The common side effects of Clodrel Plus Tablet include abdominal pain, indigestion, diarrhoea, easy bruising, and nosebleeds. Clodrel Plus Tablet is known to cause dizziness and blurry vision, so driving should be avoided. Most of these side effects of Clodrel Plus Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Stopping Clodrel Plus Tablet may worsen your condition and increase the risk of a future heart attack. Let your doctor know if are sensitive to clopidogrel or aspirin, have kidney/liver diseases, bleeding issues (like peptic ulcer, brain haemorrhage), pregnant or planning to become pregnant or breastfeeding. The patient should inform the doctor that they are taking Clodrel Plus Tablet before any surgery is scheduled or any new medicine is taken. 

Uses of Clodrel Plus Tablet

Prevention of heart attack and stroke.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Clodrel Plus Tablet is composed of Aspirin and Clopidogrel, which act as blood thinners (anti-platelet) and prevent the formation of a clot in the blood vessels. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose (about 75 mg) to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels). Clodrel Plus Tablet helps in the free flow of blood, thereby preventing heart attack, stroke, deep vein thrombosis (blood clot in the vein), and pulmonary embolism (blood clots in the arteries of lungs).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clodrel Plus Tablet

  • Abdominal pain
  • Indigestion
  • Diarrhoea
  • Easy bruising
  • Nosebleeds
  • Increased bleeding tendency

Drug Warnings

You should avoid taking Clodrel Plus Tablet if you are allergic to Clodrel Plus Tablet . Let your doctor know if you have a medical condition that is causing bleeding such as a haemophilia, stomach ulcer or bleeding within your head or bowel. Caution is required before giving Clodrel Plus Tablet to the liver or kidney problems patients. People affected with respiratory problems like asthma, rhinitis or nasal polyps should consult a doctor before intake of Clodrel Plus Tablet . Clodrel Plus Tablet is not recommended for the breastfeeding mother as it passes into the breast milk. The safety and effectiveness of Clodrel Plus Tablet in children less than 12 years of age have not been established. 

Drug-Drug Interactions

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ClopidogrelMifepristone
Critical
ClopidogrelSelexipag
Critical

Drug-Drug Interactions

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ClopidogrelMifepristone
Critical
How does the drug interact with Clodrel Plus Tablet:
Taking Clodrel Plus Tablet together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Clodrel Plus Tablet with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
ClopidogrelSelexipag
Critical
How does the drug interact with Clodrel Plus Tablet:
When Selexipag and Clodrel Plus Tablet are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Clodrel Plus Tablet with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
AspirinKetorolac tromethamine
Critical
How does the drug interact with Clodrel Plus Tablet:
Combining Ketorolac tromethamine with Clodrel Plus Tablet can increase the risk of adverse effects.

How to manage the interaction:
Taking Clodrel Plus Tablet with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
AspirinKetorolac
Critical
How does the drug interact with Clodrel Plus Tablet:
Co-administration of Ketorolac and Clodrel Plus Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Clodrel Plus Tablet is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
ClopidogrelRepaglinide
Severe
How does the drug interact with Clodrel Plus Tablet:
Clodrel Plus Tablet increases the blood levels of Repaglinide, which results in increased effectiveness of Repaglinide. When these medicines are taken together, you may experience low blood sugar (hypoglycemia).

How to manage the interaction:
Although taking Clodrel Plus Tablet with Repaglinide may result in interaction, it can be taken if prescribed by a doctor. However, if you experience any signs of hypoglycemia (low blood sugar), consult your doctor immediately. Common symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, weakness, tremor, nausea, hunger, sweating, and palpitation. It is advised to monitor your blood sugar levels if you experience the above symptoms. Do not discontinue any medication without consulting a doctor.
ClopidogrelPioglitazone
Severe
How does the drug interact with Clodrel Plus Tablet:
Taking Pioglitazone with Clodrel Plus Tablet can increases the blood levels of Pioglitazone, when these medicines are taken together, you may experience hypoglycemia (low blood sugar).

How to manage the interaction:
Taking Clodrel Plus Tablet together with Pioglitazone may lead to interaction, but it can be taken if prescribed by your doctor. Consult a doctor immediately if you experience headache, dizziness, drowsiness, nervousness, weakness, shaking, or sweating. Do not discontinue any medication without consulting the doctor.
ClopidogrelArgatroban
Severe
How does the drug interact with Clodrel Plus Tablet:
Taking Clodrel Plus Tablet together with argatroban can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Clodrel Plus Tablet and Apixaban, they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding, like feeling dizzy or lightheaded, red or black, sticky stools, or severe headaches. Do not discontinue any medications without consulting your doctor.
ClopidogrelDabigatran etexilate
Severe
How does the drug interact with Clodrel Plus Tablet:
Taking Clodrel Plus Tablet with Dabigatran may increase the risk of bleeding.

How to manage the interaction:
Although there may be an interaction between Clodrel Plus Tablet and Apixaban, they can be taken together if advised by your doctor. However, consult your doctor immediately if you experience any unusual bleeding, dizziness or lightheadedness, red or black, sticky stools, or headaches. Do not discontinue any medication without consulting your doctor.
ClopidogrelDalteparin
Severe
How does the drug interact with Clodrel Plus Tablet:
Using dalteparin together with Clodrel Plus Tablet may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Clodrel Plus Tablet and Dalteparin, but they can be taken together if prescribed by your doctor. However, If you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, or having a headache consult your doctor without any delay. Do not discontinue any medication without consulting your doctor.
ClopidogrelEnoxaparin
Severe
How does the drug interact with Clodrel Plus Tablet:
Taking enoxaparin with Clodrel Plus Tablet can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Clodrel Plus Tablet and Enoxaparin, but they can be taken together if prescribed by a doctor. However, If you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, or headache, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Clodrel Plus Tablet .
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, and vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Habit Forming

No

Therapeutic Class

PLATELET AGGREGATION INHIBITOR

Clodrel Plus Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Clodrel Plus Tablet consists Aspirin and Clopidogrel. Aspirin acts as a blood-thinning or anti-platelet agent in a low dose to prevent heart attack and stroke. Clopidogrel acts by preventing blood clots if you have severe chest pain (unstable angina or heart attack), stroke, and peripheral arterial disease (heart problem due to narrowed blood vessels).

Please consult your doctor if Clodrel Plus Tablet needs to be discontinued before undergoing surgery. The doctor might ask you to stop taking Clodrel Plus Tablet a few days before surgery since it can cause an increased risk of bleeding during surgery.

Clodrel Plus Tablet consists of Aspirin and Clopidogrel. These are blood-thinning agents and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

Clodrel Plus Tablet is generally safe to take for a long time. It works best if you take it for many months or even years. If you're at risk of getting a stomach ulcer, your doctor may prescribe a medicine to treat ulcer, while you're taking Clodrel Plus Tablet .

Drug-Drug Interactions Checker List

  • WARFARIN
  • HEPARIN
  • FLUOXETINE
  • LITHIUM
  • GLIBENCLAMIDE
  • REPAGLINIDE
  • METHOTREXATE
  • VALPROATE
  • PHENYTOIN
  • IBUPROFEN
  • OMEPRAZOLE
  • FLUCONAZOLE
  • RITONAVIR
  • COBICISTAT
  • PROBENECID

Special Advise

Let your doctor know that you are using Clodrel Plus Tablet if you have a scheduled surgery since this medicine may increase the risk of bleeding.

Disease/Condition Glossary

A blood clot is a clump or aggregation of blood that changes from a liquid to a gel-like state. Clotting is a natural process that prevents you from losing too much blood in an accident, trauma, surgery or cut. When a clot forms inside the veins, it won’t always dissolve on its own and can become even life-threatening situation.

Stroke: When our brain does not get sufficient oxygen and blood supply, it starts dying within a few minutes leading to a heart attack or stroke.

Heart attack: It occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is most often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). During a heart attack (myocardial infarction), the blood supply which nourishes the heart with oxygen is cut off. This causes the heart muscle to die. Signs of a heart attack include chest pain, upper body pain, sweating, nausea, fatigue and trouble breathing.

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