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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
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Whats That

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Composition :

DOCETAXEL-120MG

Manufacturer/Marketer :

Adley Formulations

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Adoxi 120 mg Injection 3 ml

Adoxi 120 mg Injection 3 ml belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers. Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues.

Adoxi 120 mg Injection 3 ml contains Docetaxel, which belongs to the anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent, i.e., it prevents the cancer cells from rapidly dividing and spreading.

Adoxi 120 mg Injection 3 ml will be administered by a healthcare professional. Your doctor will decide the dosage depending on your medical condition. The common side effects of Adoxi 120 mg Injection 3 ml include pain/swelling at the injection site, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, insomnia (sleeplessness), fever (please inform your doctor if you have fever), muscle aches, and breathlessness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not use or stop this medicine if the doctor did not advise you. Before starting Adoxi 120 mg Injection 3 ml, let your doctor know if you have any allergic reactions, medical history of liver or kidney diseases, heart diseases, blood pressure problems, fits, lung disorders, weak immune system, anemia, low white blood cell count, vision problems, and are receiving chemotherapy. Adoxi 120 mg Injection 3 ml is not indicated for use in pregnant and breastfeeding women. Adoxi 120 mg Injection 3 ml may make you feel dizzy and drowsy, hence do not drive or operate machinery. It is not recommended to consume alcohol along with Adoxi 120 mg Injection 3 ml. Adoxi 120 mg Injection 3 ml is not recommended for children below two years of age.

Uses of Adoxi 120 mg Injection 3 ml

Cancer.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Adoxi 120 mg Injection 3 ml contains Docetaxel that belongs to the family of anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent and prevents cancer cells from rapidly dividing and spreading. Docetaxel may be used alone or in combination with other chemotherapy drugs to treat breast cancer that has spread to the tissues and lymph nodes (locally advanced breast cancer) and other parts (secondary breast cancer). It is also used in prostate cancer that does not respond to hormone treatment. It is further being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers.

Storage

Store in a cool and dry place away from sunlight
Side effects of Adoxi 120 mg Injection 3 ml
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Include fruits, vegetables, and whole grains in your diet.
  • Exercise regularly.
  • Quit smoking as it may increase the risk of neuropathy.
  • Getting massage therapy and acupuncture might help with pain.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.

Drug Warnings

Inform your doctor if you have any allergic reactions to Adoxi 120 mg Injection 3 ml or other medications. Before starting Adoxi 120 mg Injection 3 ml, let your doctor know if you have any medical history of allergic reactions, non-small cell lung cancer, liver or kidney diseases, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Adoxi 120 mg Injection 3 ml can affect the unborn baby when used in pregnancy. It may also have harmful effects on the breastfed infant when used by a lactating mother. Hence, Adoxi 120 mg Injection 3 ml is not indicated in pregnancy and breastfeeding women. If you are using Adoxi 120 mg Injection 3 ml, use reliable contraception forms to prevent pregnancy during the course. Adoxi 120 mg Injection 3 ml can make you feel dizzy and drowsy, thus affecting your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Avoid alcohol consumption while being treated with Adoxi 120 mg Injection 3 ml. Adoxi 120 mg Injection 3 ml is not recommended for patients younger than 18 years of age.

Drug-Drug Interactions

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DocetaxelCladribine
Severe
DocetaxelCeritinib
Severe

Drug-Drug Interactions

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DocetaxelCladribine
Severe
How does the drug interact with Adoxi 120 mg Injection 3 ml:
The combined use of cladribine with Adoxi 120 mg Injection 3 ml can increase the risk of serious infections.

How to manage the interaction:
Taking Adoxi 120 mg Injection 3 ml with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
DocetaxelCeritinib
Severe
How does the drug interact with Adoxi 120 mg Injection 3 ml:
Taking ceritinib and may significantly increase the blood levels of Adoxi 120 mg Injection 3 ml.

How to manage the interaction:
Taking Adoxi 120 mg Injection 3 ml with Ceritinib together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like nausea, vomiting, diarrhea, mouth sores, fluid retention, nerve pain, numbness, tingling, muscle pain or weakness, paleness, dizziness, fainting, unusual bruising or bleeding, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to a doctor.
DocetaxelDiltiazem
Severe
How does the drug interact with Adoxi 120 mg Injection 3 ml:
When Diltiazem is taken with Adoxi 120 mg Injection 3 ml, it can slow down the breakdown of Adoxi 120 mg Injection 3 ml in the body.

How to manage the interaction:
Taking Diltiazem with Adoxi 120 mg Injection 3 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like feeling sick, throwing up, having diarrhea, mouth sores, swelling, nerve pain, or weakness, it's important to let your doctor know. They might have other options for you that won't cause these problems. Other symptoms like feeling tired, dizzy, or having trouble breathing, losing weight, or pain when you pee should also be reported to your doctor right away. Do not stop using any medications without first talking to your doctor.
DocetaxelClarithromycin
Severe
How does the drug interact with Adoxi 120 mg Injection 3 ml:
When Adoxi 120 mg Injection 3 ml is taken with Clarithromycin, it can slow down the way the body breaks down Adoxi 120 mg Injection 3 ml.

How to manage the interaction:
Taking Clarithromycin with Adoxi 120 mg Injection 3 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - feeling sick, throwing up, having diarrhea, mouth sores, retaining fluids, nerve pain, numbness, tingling, muscle pain, weakness, anemia, bleeding problems, looking pale, feeling tired, dizzy, bleeding, bruising, having a fever, chills, a sore throat, muscle aches, trouble breathing, losing weight, feeling pain or burning when you pee, or bleeding - make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
DocetaxelCiclosporin
Severe
How does the drug interact with Adoxi 120 mg Injection 3 ml:
Coadministration of Adoxi 120 mg Injection 3 ml with ciclosporin may significantly increase the blood levels of Adoxi 120 mg Injection 3 ml.

How to manage the interaction:
Although there is a possible interaction between deferasirox and ciclosporin, they can be taken together if your doctor has prescribed them. Contact your doctor immediately if experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
DocetaxelMifepristone
Severe
How does the drug interact with Adoxi 120 mg Injection 3 ml:
Co-administration of Adoxi 120 mg Injection 3 ml with mifepristone may significantly increase the levels of mifepristone, which may increase the risk of side effects.

How to manage the interaction:
Taking Adoxi 120 mg Injection 3 ml with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm(coughing fluid), red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue any medications without consulting a doctor.
DocetaxelAmiodarone
Severe
How does the drug interact with Adoxi 120 mg Injection 3 ml:
Coadministration of Amiodarone with Adoxi 120 mg Injection 3 ml may significantly increase the blood levels of Adoxi 120 mg Injection 3 ml.

How to manage the interaction:
Co-administration of Adoxi 120 mg Injection 3 ml with Amiodarone can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, make sure to consult a doctor. Do not stop using any medications without talking to a doctor.
DocetaxelKetoconazole
Severe
How does the drug interact with Adoxi 120 mg Injection 3 ml:
Coadministration of Ketoconazole and Adoxi 120 mg Injection 3 ml may significantly increase the blood levels of Adoxi 120 mg Injection 3 ml. This may increase risk of side effects.

How to manage the interaction:
Although taking Ketoconazole and Adoxi 120 mg Injection 3 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in your coughing, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, you should consult a doctor immediately. do not discontinue any medication without consulting a doctor.
DocetaxelTofacitinib
Severe
How does the drug interact with Adoxi 120 mg Injection 3 ml:
Taking Tofacitinib with Adoxi 120 mg Injection 3 ml may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and Adoxi 120 mg Injection 3 ml, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
DocetaxelVoriconazole
Severe
How does the drug interact with Adoxi 120 mg Injection 3 ml:
Taking Adoxi 120 mg Injection 3 ml with Voriconazole may significantly increase the blood levels of Adoxi 120 mg Injection 3 ml.

How to manage the interaction:
Although taking Adoxi 120 mg Injection 3 ml and Voriconazole together may result in an interaction, they can be taken together if a doctor prescribes it. However, if you experience dizziness, fever, chills, diarrhea, sore throat, muscle pain, shortness of breath, and pain or burning during urination, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a fiber-rich diet and include healthy carbohydrates from fruits, vegetables, and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli, and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Include whole grains, legumes, and follow a plant-based diet. Limiting dietary fats is advised during the breast cancer phase. Instead, include healthy fats, such as olive oil, avocado, nuts, seeds, and fatty fish
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk, and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Adoxi 120 mg Injection 3 ml contains Docetaxel, an anti-neoplastic agent. It prevents the cancer cells from rapidly dividing and spreading, thus slowing down their growth.

Adoxi 120 mg Injection 3 ml should be used with caution and under doctor's supervision only if you have any medical history of any allergic reactions, liver or kidney diseases, non-small cell lung cancer, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions (excess fluid around lungs), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Let your doctor know if you have any other medical concerns before using Adoxi 120 mg Injection 3 ml.

During treatment with Adoxi 120 mg Injection 3 ml, it is essential to look for any signs of swelling (fluid retention/oedema), dizziness/fainting, difficulty in breathing, irregular heartbeat, swelling, pain and tenderness in the abdomen region, blood in stools, skin rashes, easy bleeding or bruising, sores in the mouth or throat or symptoms of infection like fever and sore throat. If you further notice any symptoms that are not manageable or unusual, please seek prompt medical attention.

It is advised to consult your doctor before undergoing any vaccination and take advice accordingly. Also, please avoid contact with people who have recently been vaccinated with the oral polio vaccine.

Docetaxel might cause serious allergic reactions and fluid retention if you had previously experienced allergic reactions with paclitaxel and cabazitaxel. These medicines contain polysorbate 80, an excipient. If you had any allergic reactions with medicines containing polysorbate 80, Adoxi 120 mg Injection 3 ml is not recommended. Please consult your doctor for more information.

Drug-Drug Interactions Checker List

  • ITRACONAZOLE
  • ERYTHROMYCIN
  • RIFABUTIN
  • METRONIDAZOLE
  • TINIDAZOLE
  • RITONAVIR
  • DISULFIRAM
  • CODEINE
  • HYDROCODONE
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • DIPHENHYDRAMINE

Special Advise

  • Your doctor may advise regular physical exams and mammograms to rule out the possibility of breast cancer.
  • Self-examine your breasts to check for any lumps monthly.
  • Your doctor may also advise liver function tests to monitor your liver health.
  • Your doctor may advise blood tests and regular examinations of the prostate.

Disease/Condition Glossary

Cancer: It is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Cancer growth can be prevented by chemotherapy (by strong antibiotics), radiation, and stem cell therapy.

Breast cancer:  It is a type of cancer that develops in breast cells stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue, or the fibrous connective tissue within the breast. Symptoms include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size, or appearance of the breast, and a lump or swelling under the arm. 

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