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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
COD available

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Whats That

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Composition

DOCETAXEL-120MG

Manufacturer/Marketer

Vhb Life Sciences Inc

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Detaxl 120 mg Injection 3 ml

Detaxl 120 mg Injection 3 ml belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers. Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues.

Detaxl 120 mg Injection 3 ml contains Docetaxel, which belongs to the anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent, i.e., it prevents the cancer cells from rapidly dividing and spreading.

Detaxl 120 mg Injection 3 ml will be administered by a healthcare professional. Your doctor will decide the dosage depending on your medical condition. The common side effects of Detaxl 120 mg Injection 3 ml include pain/swelling at the injection site, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, insomnia (sleeplessness), fever (please inform your doctor if you have fever), muscle aches, and breathlessness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not use or stop this medicine if the doctor did not advise you. Before starting Detaxl 120 mg Injection 3 ml, let your doctor know if you have any allergic reactions, medical history of liver or kidney diseases, heart diseases, blood pressure problems, fits, lung disorders, weak immune system, anemia, low white blood cell count, vision problems, and are receiving chemotherapy. Detaxl 120 mg Injection 3 ml is not indicated for use in pregnant and breastfeeding women. Detaxl 120 mg Injection 3 ml may make you feel dizzy and drowsy, hence do not drive or operate machinery. It is not recommended to consume alcohol along with Detaxl 120 mg Injection 3 ml. Detaxl 120 mg Injection 3 ml is not recommended for children below two years of age.

Uses of Detaxl 120 mg Injection 3 ml

Cancer.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Detaxl 120 mg Injection 3 ml contains Docetaxel that belongs to the family of anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent and prevents cancer cells from rapidly dividing and spreading. Docetaxel may be used alone or in combination with other chemotherapy drugs to treat breast cancer that has spread to the tissues and lymph nodes (locally advanced breast cancer) and other parts (secondary breast cancer). It is also used in prostate cancer that does not respond to hormone treatment. It is further being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Detaxl 120 mg Injection 3 ml

  • Pain/swelling at the injection site
  • Headache
  • Fatigue
  • Dizziness
  • Drowsiness
  • Constipation
  • Loss of appetite
  • Indigestion
  • Tearing of the eyes
  • Nausea
  • Vomiting
  • Diarrhoea
  • Insomnia (sleeplessness)
  • Fever (please inform your doctor if you have fever)
  • Muscle aches
  • Breathlessness

Drug Warnings

Inform your doctor if you have any allergic reactions to Detaxl 120 mg Injection 3 ml or other medications. Before starting Detaxl 120 mg Injection 3 ml, let your doctor know if you have any medical history of allergic reactions, non-small cell lung cancer, liver or kidney diseases, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Detaxl 120 mg Injection 3 ml can affect the unborn baby when used in pregnancy. It may also have harmful effects on the breastfed infant when used by a lactating mother. Hence, Detaxl 120 mg Injection 3 ml is not indicated in pregnancy and breastfeeding women. If you are using Detaxl 120 mg Injection 3 ml, use reliable contraception forms to prevent pregnancy during the course. Detaxl 120 mg Injection 3 ml can make you feel dizzy and drowsy, thus affecting your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Avoid alcohol consumption while being treated with Detaxl 120 mg Injection 3 ml. Detaxl 120 mg Injection 3 ml is not recommended for patients younger than 18 years of age.

Drug-Drug Interactions

verifiedApollotooltip
DocetaxelKetoconazole
Severe
DocetaxelItraconazole
Severe

Drug-Drug Interactions

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DocetaxelKetoconazole
Severe
How does the drug interact with Detaxl 120 mg Injection 3 ml:
Coadministration of Ketoconazole and Detaxl 120 mg Injection 3 ml may significantly increase the blood levels of Detaxl 120 mg Injection 3 ml. This may increase risk of side effects.

How to manage the interaction:
Although taking Ketoconazole and Detaxl 120 mg Injection 3 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in your coughing, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, you should consult a doctor immediately. do not discontinue any medication without consulting a doctor.
DocetaxelItraconazole
Severe
How does the drug interact with Detaxl 120 mg Injection 3 ml:
Coadministration of Itraconazole may significantly increase the blood levels of Detaxl 120 mg Injection 3 ml.

How to manage the interaction:
Although there is a possible interaction between Detaxl 120 mg Injection 3 ml and Itraconazole, they can be taken in case a doctor prescribes it. Consult a doctor if you notice any of the following symptoms: paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhoea, sore throat, aches in the muscles, shortness of breath, blood in the phlegm, red or irritated skin, body sores, or pain or burning when urinating. Never stop taking any medications without talking to a doctor.
DocetaxelCiclosporin
Severe
How does the drug interact with Detaxl 120 mg Injection 3 ml:
Coadministration of Detaxl 120 mg Injection 3 ml with ciclosporin may significantly increase the blood levels of Detaxl 120 mg Injection 3 ml.

How to manage the interaction:
Although there is a possible interaction between deferasirox and ciclosporin, they can be taken together if your doctor has prescribed them. Contact your doctor immediately if experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
DocetaxelClozapine
Severe
How does the drug interact with Detaxl 120 mg Injection 3 ml:
Taking Detaxl 120 mg Injection 3 ml and clozapine can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Detaxl 120 mg Injection 3 ml and Clozapine, but it can be taken if prescribed by a doctor. If you're taking clozapine and also taking medications that can affect your bone marrow or cause agranulocytosis, be careful and get regular check-ups. If you notice any symptoms like infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain while urinating, call your doctor right away. Do not discontinue any medications without first consulting your doctor.
DocetaxelEtanercept
Severe
How does the drug interact with Detaxl 120 mg Injection 3 ml:
When Etanercept is used with Detaxl 120 mg Injection 3 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Etanercept with Detaxl 120 mg Injection 3 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not discontinue any medications without a doctor's advice.
DocetaxelAmiodarone
Severe
How does the drug interact with Detaxl 120 mg Injection 3 ml:
Coadministration of Amiodarone with Detaxl 120 mg Injection 3 ml may significantly increase the blood levels of Detaxl 120 mg Injection 3 ml.

How to manage the interaction:
Co-administration of Detaxl 120 mg Injection 3 ml with Amiodarone can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, make sure to consult a doctor. Do not stop using any medications without talking to a doctor.
DocetaxelInfliximab
Severe
How does the drug interact with Detaxl 120 mg Injection 3 ml:
When Detaxl 120 mg Injection 3 ml is taken with Infliximab, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab with Detaxl 120 mg Injection 3 ml together can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, contact a doctor right away. Do not stop using any medications without a doctor's advice.
DocetaxelTofacitinib
Severe
How does the drug interact with Detaxl 120 mg Injection 3 ml:
Taking Tofacitinib with Detaxl 120 mg Injection 3 ml may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Tofacitinib and Detaxl 120 mg Injection 3 ml, you can take these medicines together if prescribed by your doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
DocetaxelMifepristone
Severe
How does the drug interact with Detaxl 120 mg Injection 3 ml:
Co-administration of Detaxl 120 mg Injection 3 ml with mifepristone may significantly increase the levels of mifepristone, which may increase the risk of side effects.

How to manage the interaction:
Taking Detaxl 120 mg Injection 3 ml with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm(coughing fluid), red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue any medications without consulting a doctor.
DocetaxelRitonavir
Severe
How does the drug interact with Detaxl 120 mg Injection 3 ml:
Taking Ritonavir and Detaxl 120 mg Injection 3 ml may significantly increase the blood levels of Detaxl 120 mg Injection 3 ml.

How to manage the interaction:
Taking Detaxl 120 mg Injection 3 ml with Ritonavir together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms feeling sick, having diarrhea, sores in your mouth, retaining fluids, experiencing nerve pain, numbness or tingling, muscle pain or weakness, feeling tired, dizzy or faint, having trouble with bleeding or bruising, having a fever or chills, a sore throat, muscle aches, difficulty breathing, feeling pain or burning when you pee, or bleeding contact a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a fiber-rich diet and include healthy carbohydrates from fruits, vegetables, and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli, and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Include whole grains, legumes, and follow a plant-based diet. Limiting dietary fats is advised during the breast cancer phase. Instead, include healthy fats, such as olive oil, avocado, nuts, seeds, and fatty fish
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk, and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Detaxl 120 mg Injection 3 ml Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Detaxl 120 mg Injection 3 ml contains Docetaxel, an anti-neoplastic agent. It prevents the cancer cells from rapidly dividing and spreading, thus slowing down their growth.

Detaxl 120 mg Injection 3 ml should be used with caution and under doctor's supervision only if you have any medical history of any allergic reactions, liver or kidney diseases, non-small cell lung cancer, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions (excess fluid around lungs), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Let your doctor know if you have any other medical concerns before using Detaxl 120 mg Injection 3 ml.

During treatment with Detaxl 120 mg Injection 3 ml, it is essential to look for any signs of swelling (fluid retention/oedema), dizziness/fainting, difficulty in breathing, irregular heartbeat, swelling, pain and tenderness in the abdomen region, blood in stools, skin rashes, easy bleeding or bruising, sores in the mouth or throat or symptoms of infection like fever and sore throat. If you further notice any symptoms that are not manageable or unusual, please seek prompt medical attention.

It is advised to consult your doctor before undergoing any vaccination and take advice accordingly. Also, please avoid contact with people who have recently been vaccinated with the oral polio vaccine.

Docetaxel might cause serious allergic reactions and fluid retention if you had previously experienced allergic reactions with paclitaxel and cabazitaxel. These medicines contain polysorbate 80, an excipient. If you had any allergic reactions with medicines containing polysorbate 80, Detaxl 120 mg Injection 3 ml is not recommended. Please consult your doctor for more information.

Drug-Drug Interactions Checker List

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Special Advise

  • Your doctor may advise regular physical exams and mammograms to rule out the possibility of breast cancer.
  • Self-examine your breasts to check for any lumps monthly.
  • Your doctor may also advise liver function tests to monitor your liver health.
  • Your doctor may advise blood tests and regular examinations of the prostate.

Disease/Condition Glossary

Cancer: It is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Cancer growth can be prevented by chemotherapy (by strong antibiotics), radiation, and stem cell therapy.

Breast cancer:  It is a type of cancer that develops in breast cells stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue, or the fibrous connective tissue within the breast. Symptoms include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size, or appearance of the breast, and a lump or swelling under the arm. 

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