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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Synonym

DOXORUBICIN HYDROCHLORIDE

Composition

DOXORUBICIN-10MG

Manufacturer/Marketer

Oncostar Pharma Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Adrimos 10 Injection 1's

Adrimos 10 Injection 1's is an anti-cancer medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. Adrimos 10 Injection 1's is primarily used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer (abnormal growth in the cells of the breast). It is also used to treat neuroblastoma (cancer that starts in nerve cells and primarily affects children) and Wilms' tumor (a form of kidney cancer that affects children).

Adrimos 10 Injection 1's contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, destroying DNA and RNA synthesis.

Adrimos 10 Injection 1's may cause certain side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, red discoloration of urine, diarrhea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer Adrimos 10 Injection 1's. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Adrimos 10 Injection 1's should be avoided if you are allergic to it or any other components of this medicine. It is contraindicated in patients having severe myocardial insufficiency, a recent history of myocardial infarction (MI), severe persistent drug-induced myelosuppression, and severe liver disease. Hence, if you have any such conditions, inform your doctor. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any CYP3A4 or CYP2D6 inducers medication, as it can cause adverse effects. Adrimos 10 Injection 1's is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand.

Uses of Adrimos 10 Injection 1's

Breast Cancer

Directions for Use

A trained healthcare professional will administer Adrimos 10 Injection 1's. Hence, do not self-administer.

Medicinal Benefits

Adrimos 10 Injection 1's contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Adrimos 10 Injection 1's is also used in the treatment of acute lymphoblastic leukaemia, acute myeloblastic leukaemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, metastatic breast cancer, metastatic Wilms’ tumour, metastatic neuroblastoma, metastatic soft tissue sarcoma, metastatic bone sarcomas, metastatic ovarian carcinoma, metastatic transitional cell bladder carcinoma, metastatic thyroid carcinoma, metastatic gastric carcinoma, metastatic bronchogenic carcinoma

Storage

Store in a cool and dry place away from sunlight

Side Effects of Adrimos 10 Injection 1's

  • Nausea
  • Abdominal pain
  • Vomiting
  • Dizziness
  • Back pain
  • Pain at the site of injection
  • Red discolouration of urine
  • Loss of appetite
  • Mouth sores
  • Tiredness
  • Weight gain

Drug Warnings

Adrimos 10 Injection 1's should be avoided if you are allergic to it. It is contraindicated in patients having severe myocardial insufficiency, a recent history of myocardial infarction (MI), severe persistent drug-induced myelosuppression and severe liver disease. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any CYP3A4 or CYP2D6 inducers medication, as it can cause serious adverse effects. Adrimos 10 Injection 1's is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Do not stop receiving Adrimos 10 Injection 1's without a doctor’s advice, as it can cause serious health conditions. Adrimos 10 Injection 1's is known to cause secondary malignancies, tissue necrosis, cardiomyopathy and septic shock in some patients. Hence careful monitoring of the patient is needed while receiving the medicine.

Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables, and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Adrimos 10 Injection 1's Substitute

Substitutes safety advice
  • Doxotero 10 mg Injection 1's

    by Others

    159.80per tablet
  • Doxorubin 10 mg Injection 5 ml

    by Others

    38.14per tablet
  • Doxilyd 10 mg Injection 1's

    by Others

    199.80per tablet
  • DOXUTEC 10MG INJECTION 5ML

    by Others

    40.86per tablet
  • Doxocare 10 Injection 1's

    by Others

    156.60per tablet

FAQs

Adrimos 10 Injection 1's contains Doxorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.

Adrimos 10 Injection 1's can disrupt a woman's natural menstrual cycle (period) and inhibit sperm production in men. However, you should not presume that you cannot become pregnant or that you cannot make someone else pregnant. It may also harm your foetus. Use reliable methods of birth control while on treatment with Adrimos 10 Injection 1's.

Drug-Drug Interactions Checker List

  • PHENYTOIN
  • PHENOBARBITAL
  • RIFAMPICIN
  • CLARITHROMYCIN
  • VORICONAZOLE
  • CYCLOSPORIN
  • BUPROPION
  • PAROXETINE
  • FLUOXETINE
  • DEXAMETHASONE
  • HALOPERIDOL

Special Advise

  • Avoid intercourse while on treatment with Adrimos 10 Injection 1's.
  • Regular complete blood count monitoring is advised.  Also, monitoring of liver function is important while receiving Adrimos 10 Injection 1's.
  • According to postmarketing reports, juvenile children receiving doxorubicin hydrochloride are at risk of developing late cardiovascular dysfunction. Risk factors include early age during treatment (particularly five years), large cumulative dosages, and receipt of multimodal modality therapy. All pediatric patients who have received doxorubicin hydrochloride should undergo long-term cardiovascular monitoring.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer with abnormal growth in the cells of the breast. There are different kinds of breast cancer, such as cancer occurring in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. Symptoms of breast cancer include a lump in the breast, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, a lump or swelling under the arm, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin. 

Lymphoma: Lymphoma is a wide word for cancer that develops in lymph system cells. Hodgkin lymphoma and non-Hodgkin lymphoma (NHL) are the two most common kinds. Hodgkin lymphoma is frequently curable.

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