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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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in last 30 days

Manufacturer/Marketer

Systopic Laboratories Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About AF 300 Tablet 1's

AF 300 Tablet 1's belongs to the class of medicines called 'antifungals' used to treat a broad range of infections caused due to fungi and yeast. A fungal infection is caused when a fungus invades and affects any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood.

AF 300 Tablet 1's contains ‘Fluconazole’ that kills or prevents fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, which interferes with the formation of the fungal cell membrane. As a result, fungal or yeast cells get killed or their growth is minimized.

Take this medicine as prescribed by your doctor. AF 300 Tablet 1's has common side effects like headache, diarrhoea, nausea, stomach upset, dizziness, stomach pain, and altered food tastes. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you are allergic to AF 300 Tablet 1's or any of its components. Let your doctor know if you have any liver, kidney or heart problems before starting AF 300 Tablet 1's. Pregnant and breastfeeding women should consult their doctor before starting AF 300 Tablet 1's. It is advised to avoid alcohol intake while using AF 300 Tablet 1's to prevent any undesirable effects.

Uses of AF 300 Tablet 1's

Fungal infections.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral liquid: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

AF 300 Tablet 1's works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation. It is used to treat various fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), candida infections (urinary tract infections, peritonitis), and cryptococcal meningitis. Besides this, AF 300 Tablet 1's is also used to prevent candidiasis and coccidioidomycosis in patients who receive cancer or radiation treatment while undergoing bone marrow transplantation. AF 300 Tablet 1's is effective in treating soft tissue and pulmonary infections when compared to other azole antifungal drugs.

Storage

Store in a cool and dry place away from sunlight

Side Effects of AF 300 Tablet 1's

  • Headache
  • Diarrhoea
  • Nausea
  • Stomach upset
  • Dizziness
  • Stomach pain
  • Altered food tastes

Drug Warnings

Please inform your doctor if you use any prescription, or non-prescription medicines, including vitamin and herbal supplements before using AF 300 Tablet 1's. Do not use AF 300 Tablet 1's if you are allergic to AF 300 Tablet 1's or any of its components. Let your doctor know if you have any liver, kidney, or heart problems before starting AF 300 Tablet 1's. This medicine may not be suitable for some people who have a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels; however, please seek medical advice. Pregnant or lactating women should consult the doctor before taking the AF 300 Tablet 1's. Do not drive or operate machinery if you experience dizziness or other side effects that may affect your mental ability to drive. Avoid alcohol consumption along with AF 300 Tablet 1's to avoid undesirable effects 

Drug-Drug Interactions

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FluconazoleErythromycin
Critical
FluconazoleAstemizole
Critical

Drug-Drug Interactions

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FluconazoleErythromycin
Critical
How does the drug interact with AF 300 Tablet:
Taking AF 300 Tablet with Erythromycin can increase the risk of heart rhythm problems.

How to manage the interaction:
Taking AF 300 Tablet with Erythromycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleAstemizole
Critical
How does the drug interact with AF 300 Tablet:
When Astemizole is taken with AF 300 Tablet, the body's ability to break down Astemizole may be reduced.

How to manage the interaction:
Taking AF 300 Tablet with Astemizole can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without of consulting a doctor.
FluconazoleLomitapide
Critical
How does the drug interact with AF 300 Tablet:
When Lomitapide is taken with AF 300 Tablet, may increase the blood levels of lomitapide.

How to manage the interaction:
Taking AF 300 Tablet with Lomitapide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FluconazoleEliglustat
Critical
How does the drug interact with AF 300 Tablet:
When Eliglustat and AF 300 Tablet are taken together, AF 300 Tablet can significantly increase the blood levels of eliglustat.

How to manage the interaction:
Taking AF 300 Tablet with Eliglustat together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleGlimepiride
Severe
How does the drug interact with AF 300 Tablet:
Co-administration of AF 300 Tablet may increase the blood levels and effects of Glimepiride may cause low blood glucose.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with AF 300 Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
FluconazoleDeflazacort
Severe
How does the drug interact with AF 300 Tablet:
Co-administration of AF 300 Tablet with Deflazacort can increase the levels of Deflazacort in the body.

How to manage the interaction:
Taking AF 300 Tablet with Deflazacort together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like muscle weakness, excessive growth of facial or body hair, or sudden dizziness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FluconazoleEfavirenz
Severe
How does the drug interact with AF 300 Tablet:
Taking AF 300 Tablet with Efavirenz can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, AF 300 Tablet can be taken with Efavirenz if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue any medication without consulting a doctor.
FluconazoleIloperidone
Severe
How does the drug interact with AF 300 Tablet:
Taking AF 300 Tablet with Iloperidone can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, AF 300 Tablet can be taken with Iloperidone if prescribed by the doctor. Consult the doctor if you experience sudden lightheadedness, dizziness, shortness of breath, fainting, or heart palpitations during treatment with these medications. Do not discontinue the medication without consulting a doctor.
FluconazoleMoxifloxacin
Severe
How does the drug interact with AF 300 Tablet:
Taking AF 300 Tablet with Moxifloxacin can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction, AF 300 Tablet can be taken with Moxifloxacin if prescribed by the doctor. Consult the doctor if you experience dizziness, shortness of breath, or irregular heartbeat consult a doctor. Do not discontinue the medications without consulting a doctor.
FluconazoleSimeprevir
Severe
How does the drug interact with AF 300 Tablet:
Co-administration of Simeprevir with AF 300 Tablet may significantly increase the blood levels of Simeprevir.

How to manage the interaction:
Although there is a possible interaction between AF 300 Tablet and Simeprevir, you can take these medicines together if prescribed by a doctor. If you're having a skin rash or sensitivity to light, it's important to let a doctor know right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid frequent douching to maintain the natural moisture in the vagina.
  • Use mild soap while taking baths and prefer warm baths.
  • Avoid harsh products on your skin.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Avoid or limit the intake of alcohol and caffeine.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, and alcohol, and includes low-sugar fruits, non-starchy vegetables, and gluten-free foods.
  • A very-high sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

AF 300 Tablet 1's Substitute

Substitutes safety advice
  • Micoflu-300 Tablet 10's

    by Others

    16.20per tablet

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

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FLUCONAZOLE-300MGOther diseases of liver
Severe
FLUCONAZOLE-300MGOther cardiac arrhythmias
Moderate

Drug-Diseases Interactions

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FLUCONAZOLE-300MGOther diseases of liver
Severe
How does the disease interact with AF 300 Tablet:
Hepatotoxicity has only sometimes been linked to the usage of AF 300 Tablet. There have been cases of reversible idiosyncratic hepatitis, cholestasis, and deadly fulminant hepatic failure; the latter generally affects people with substantial underlying medical disorders who are also taking several concurrent drugs. Patients with pre-existing hepatic problems should have periodic liver function tests done, especially during prolonged medication. If liver enzyme levels continue to rise or worsen, treatment should be stopped.

How to manage the interaction:
In patients with preexisting liver abnormalities, particularly during prolonged therapy, liver function tests should be done regularly. Treatment should be withdrawn if persistent elevations or worsening of liver enzyme levels occur.
FLUCONAZOLE-300MGOther cardiac arrhythmias
Moderate
How does the disease interact with AF 300 Tablet:
The QT interval on the ECG has been shown to be prolonged by some azole antifungals. During postmarketing experience, there have been a few isolated incidences of QT prolongation and torsade de pointes; these reports typically involved critically ill patients with a number of complicating risk factors, including structural cardiac disease, electrolyte problems, and concurrent medicines. Patients with illnesses that could cause proarrhythmic symptoms should take these medications cautiously. It is best to avoid using drugs that could potentially enhance the risk of cardiotoxicity concurrently.

How to manage the interaction:
It should be administered with caution to patients with heart problems. Concomitant use with other medications that have potential to increase the risk of cardiotoxicity should be avoided.
FLUCONAZOLE-300MGCare involving dialysis
Moderate
How does the disease interact with AF 300 Tablet:
Hemodialysis effectively removes AF 300 Tablet from the body. Following three hours of dialysis, it has been demonstrated that plasma levels of AF 300 Tablet decrease by 50%. After hemodialysis, AF 300 Tablet should be taken.

How to manage the interaction:
AF 300 Tablet should be administered after hemodialysis.

Drug-Drug Interactions Checker List

  • PIMOZIDE
  • QUETIAPINE
  • ERYTHROMYCIN
  • ERGOTAMINE
  • AMIODARONE
  • WARFARIN
  • CARBAMAZEPINE
  • LOSARTAN
  • METFORMIN
  • REBOXETINE

Special Advise

It is advised to reach out to your doctor if the infection symptoms persist or worsen after two weeks of treatment. 

Disease/Condition Glossary

Fungal infection occurs when a fungus enters, infects, and multiplies in the body. Fungi can live in water, soil, air, and plants. Fungi affect any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood. Mild fungal skin infections are common and can cause rashes. Fungal infections affecting body organs like the lungs can cause flu or tuberculosis. Some fungal diseases like cryptococcal meningitis and blood infections can be fatal. A few common fungal infections are yeast infections that affect the genital area, oesophagus, and urinary tract caused by the species Candida. 

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