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  3. Afdcain 2% Inj 30Ml

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
COD available

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Whats That

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Composition :

LIDOCAINE-2%

Manufacturer/Marketer :

Optima Healthcare Solutions

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Afdcain 2% Injection

Afdcain 2% Injection is indicated for the production of regional or local anaesthesia during surgery or medical procedures. Additionally, it is indicated in the management of ventricular arrhythmia (abnormal heartbeat) associated with acute myocardial infarction, or cardiac surgery. 

Afdcain 2% Injection contains ‘Lidocaine’ that blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses; hence providing an anaesthetic effect. Afdcain 2% Injection blocks cardiac sodium channels, thereby treating arrhythmia.

Afdcain 2% Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as dizziness, high/low blood pressure, nausea, vomiting, and paresthesia (burning or prickling sensation). You are advised to talk to your doctor if you experience these side effects persistently.

Do not take Afdcain 2% Injection if you are allergic to any of its components. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Avoid driving or operating machinery as Afdcain 2% Injection may cause dizziness, drowsiness, and loss of sensation. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Afdcain 2% Injection

Local anesthesia, ventricular arrhythmia.

Directions for Use

Afdcain 2% Injection will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Afdcain 2% Injection is indicated for the production of regional or local anaesthesia in case of surgeries or medical procedures. Also, it is indicated in the management of ventricular arrhythmias (abnormal heartbeat) associated with acute myocardial infarction, or cardiac surgery. Afdcain 2% Injection blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses and hence providing an anaesthetic effect. It blocks cardiac sodium channels, thereby treating arrhythmia.

Storage

Keep Afdcain 2% Injection out of reach and sight of children.

Drug Warnings

Do not take Afdcain 2% Injection if you are allergic to any of its components. Inform your doctor if you have hypovolemia (low blood volume), blood clotting problems, bleeding problems, slow heart rate, myasthenia gravis (muscle problems), epilepsy, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Avoid driving or operating machinery as Afdcain 2% Injection may cause dizziness, drowsiness and loss of sensation. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Drug-Drug Interactions

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LidocaineArbutamine
Critical
LidocaineSaquinavir
Critical

Drug-Drug Interactions

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LidocaineArbutamine
Critical
How does the drug interact with Afdcain 2% Inj 30Ml:
Taking Afdcain 2% Inj 30Ml and Arbutamine together can affect the rhythm of your heart.

How to manage the interaction:
Taking Afdcain 2% Inj 30Ml with arbutamine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience irregular heartbeat, chest tightness, blurred vision and nausea. Do not discontinue any medication without consulting a doctor.
LidocaineSaquinavir
Critical
How does the drug interact with Afdcain 2% Inj 30Ml:
Taking Afdcain 2% Inj 30Ml with Saquinavir can increase the blood levels of Afdcain 2% Inj 30Ml and cause an irregular heart rhythm.

How to manage the interaction:
Taking Afdcain 2% Inj 30Ml with Saquinavir is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting and rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Afdcain 2% Inj 30Ml:
Coadministration of Ifosfamide with Afdcain 2% Inj 30Ml can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
There may be a possibility of interaction between Ifosfamide and Afdcain 2% Inj 30Ml, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Afdcain 2% Inj 30Ml:
Taking Afdcain 2% Inj 30Ml with Sulfadiazine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Afdcain 2% Inj 30Ml with Sulfadiazine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Afdcain 2% Inj 30Ml:
Taking Rasburicase with Afdcain 2% Inj 30Ml can increase the risk of methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Rasburicase with Afdcain 2% Inj 30Ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Afdcain 2% Inj 30Ml:
Taking Afdcain 2% Inj 30Ml with bupropion can increase the risk of seizures(fits).

How to manage the interaction:
Co-administration of bupropion along with Afdcain 2% Inj 30Ml can lead to an interaction, it can be taken if recommended by a doctor. In case you experience any unusual side effects, consult a doctor. Do not discontinue any medications without consulting a doctor.
LidocaineIomeprol
Severe
How does the drug interact with Afdcain 2% Inj 30Ml:
Taking Afdcain 2% Inj 30Ml and Iomeprol may increase the risk of causing seizures(fits).

How to manage the interaction:
There may be a possibility of interaction between Afdcain 2% Inj 30Ml and Iomeprol, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Afdcain 2% Inj 30Ml:
Taking Afdcain 2% Inj 30Ml with Cyclophosphamide may increase the risk of methemoglobinemia (a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Although there is a possible interaction, cyclophosphamide can be taken with Afdcain 2% Inj 30Ml if prescribed by the doctor. However, consult the doctor if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue the medication without consulting a doctor.
LidocaineDofetilide
Severe
How does the drug interact with Afdcain 2% Inj 30Ml:
Taking Afdcain 2% Inj 30Ml together with Dofetilide can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
There may be a possibility of interaction between Afdcain 2% Inj 30Ml and Dofetilide, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without first consulting your doctor.
LidocainePrilocaine
Severe
How does the drug interact with Afdcain 2% Inj 30Ml:
Taking Afdcain 2% Inj 30Ml with Prilocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Taking Afdcain 2% Inj 30Ml with Prilocaine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include a diet rich in whole grains, lean proteins, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with a proper diet and safe exercises.
  • Manage stress with meditation and yoga.

Side Effects of Afdcain 2% Injection

  • Nausea
  • Vomiting
  • High/low blood pressure
  • Dizziness
  • Paresthesia (burning or prickling sensation)

Habit Forming

No

Therapeutic Class

VASOPRESSORS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Afdcain 2% Injection blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses and hence providing an anaesthetic effect. Afdcain 2% Injection blocks cardiac sodium channels, thereby treats arrhythmia.

Afdcain 2% Injection may cause hypotension (low blood pressure) or hypertension (high blood pressure). Therefore, regular monitoring of blood pressure is advised whilst on treatment with Afdcain 2% Injection.

Nausea and vomiting might be a side effect of Afdcain 2% Injection. It is not necessary for everyone taking Afdcain 2% Injection to experience these side effects. However, if the condition persists or worsens, please consult a doctor.

Afdcain 2% Injection might increase creatinine phosphokinase levels. Therefore, if you are undergoing any tests, inform the person doing the tests that you have taken Afdcain 2% Injection.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • PROPRANOLOL
  • AMIODARONE
  • EPINEPHRINE
  • NOREPINEPHRINE
  • CIMETIDINE
  • PHENOBARBITAL
  • PHENYTOIN
  • CARBAMAZEPINE
  • PRIMIDONE
  • ERYTHROMYCIN
  • FLUVOXAMINE

Disease/Condition Glossary

Local anaesthesia: It causes numbing/loss of sensation to a specific area of the body. It is used to treat pain, or to prevent pain during surgery or medical procedure.

Ventricular arrhythmia: Ventricular arrhythmia is a condition in which abnormal heartbeats originate in the ventricles (lower chambers of the heart). This limits/prevents the heart's ability to pump blood throughout the body. Symptoms include palpitations (a feeling as if the heart is pounding), chest pain, fainting, sweating, shortness of breath, and light-headedness.

Have a query?

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Alcohol

Caution

It is not known if alcohol affects Afdcain 2% Injection. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Your doctor will decide if Afdcain 2% Injection can be taken by breastfeeding mothers or not.

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Driving

Caution

Avoid driving or operating machinery as Afdcain 2% Injection may cause dizziness, drowsiness and loss of sensation.

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Liver

Caution

Afdcain 2% Injection should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Afdcain 2% Injection should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have any concerns regarding this.

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Children

Caution

Limited information is available. Please consult your doctor if you have any concerns regarding the usage of Afdcain 2% Injection in children.

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