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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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ORAL

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Not Returnable

About AFF 10mg/160mg/5mg Tablet

AFF 10mg/160mg/5mg Tablet is a combination of Lipid-lowering agents and Vitamins. It is used to lower the high cholesterol or increased cholesterol levels and triglycerides in the blood when a low-fat diet and lifestyle modifications have failed. High cholesterol is a condition in which you have too many lipids (fats) in your blood. It is also called hyperlipidemia or hypercholesterolemia.

AFF 10mg/160mg/5mg Tablet contains Atorvastatin, Fenofibrate and Folic Acid. Atorvastatin prevents your body from making 'bad' cholesterol (LDL), while Fenofibrate works by lowering the levels of triglycerides in your blood. Additionally, they raise 'good' cholesterol (HDL) levels. Folic Acid reduces the levels of a harmful substance (homocysteine), thereby decreasing cholesterol synthesis.

Take AFF 10mg/160mg/5mg Tablet as prescribed. Your doctor will advise how often you take AFF 10mg/160mg/5mg Tablet based on your medical condition. In some cases, you may experience hyperglycemia (excess of glucose in the bloodstream), nausea, stomach pain, constipation, flatulence, headaches and muscle pain. Most of these side effects of AFF 10mg/160mg/5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

It is recommended not to take AFF 10mg/160mg/5mg Tablet if you are allergic to any components present in it. Do not take AFF 10mg/160mg/5mg Tablet on your own if you are pregnant or a nursing mother unless prescribed by the doctor. Keep your doctor informed about your medical condition and all the medicines you are taking before taking AFF 10mg/160mg/5mg Tablet to rule out any side effects. Consuming alcohol along with AFF 10mg/160mg/5mg Tablet is not advisable.

Uses of AFF 10mg/160mg/5mg Tablet

High Cholesterol and High Triglycerides

Directions for Use

Swallow the tablet as a whole with a glass of water. Do not break, chew or crush it.

Medicinal Benefits

AFF 10mg/160mg/5mg Tablet is a combination of two Lipid-lowering agents and a Vitamin. It effectively lowers your body's high cholesterol levels. Lowering your cholesterol levels reduces your risk of heart disease and allows you to live a healthier life for longer. It also contains nutritional supplements that are necessary for overall health improvement. To maximize this medicine's effectiveness, take it regularly and make appropriate lifestyle changes (such as eating healthy and staying active).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking the AFF 10mg/160mg/5mg Tablet, let your doctor know about all your medical conditions (especially liver or kidney disease, cholelithiasis or gallstones, anaemia and muscle problems), sensitivities or allergic conditions, and all medications you are using. And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Avoid drinking alcohol while on this medication, as it can raise triglyceride levels and may increase your risk of liver damage. If you notice any persistent side effects, please consult a doctor immediately.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with AFF 10mg/160mg/5mg Tablet:
Taking AFF 10mg/160mg/5mg Tablet with Posaconazole can increase the blood levels of AFF 10mg/160mg/5mg Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with AFF 10mg/160mg/5mg Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with AFF 10mg/160mg/5mg Tablet:
Trimethoprim may decrease the blood levels and effects of AFF 10mg/160mg/5mg Tablet.

How to manage the interaction:
Although there is a possible interaction between AFF 10mg/160mg/5mg Tablet and Trimethoprim, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting your doctor.
How does the drug interact with AFF 10mg/160mg/5mg Tablet:
Coadministration of AFF 10mg/160mg/5mg Tablet and Cholestyramine may interfere with the absorption of AFF 10mg/160mg/5mg Tablet.

How to manage the interaction:
Although taking Cholestyramine and AFF 10mg/160mg/5mg Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with AFF 10mg/160mg/5mg Tablet:
Co-administration of AFF 10mg/160mg/5mg Tablet with Capecitabine may increase the risk of serious side effects such as bleeding problems, anemia, infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between AFF 10mg/160mg/5mg Tablet and Capecitabine, you can use these medicines together if prescribed by the doctor. However, if you experience paleness of skin, diarrhea, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body aches, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling sensation in the hands and feet, contact a doctor. Do not discontinue the medication without consulting a doctor. Do not discontinue the medication without consulting a doctor.
How does the drug interact with AFF 10mg/160mg/5mg Tablet:
Coadministration of AFF 10mg/160mg/5mg Tablet and Carbamazepine may reduce the blood levels of AFF 10mg/160mg/5mg Tablet.

How to manage the interaction:
Although there is a possible interaction between AFF 10mg/160mg/5mg Tablet and Carbamazepine, you can take these medicines together if prescribed by your doctor. However, if your condition changes or you experience loss of seizure control, contact your doctor.
How does the drug interact with AFF 10mg/160mg/5mg Tablet:
Sulfadiazine may decrease the blood levels and effects of AFF 10mg/160mg/5mg Tablet.

How to manage the interaction:
Although there is a possible interaction between AFF 10mg/160mg/5mg Tablet and Sulfadiazine, you can take these medicines together if prescribed by your doctor.
How does the drug interact with AFF 10mg/160mg/5mg Tablet:
Coadministration of AFF 10mg/160mg/5mg Tablet and Fluorouracil may increase the effects of Fluorouracil and increase the risk of serious side effects such as bleeding problems, anaemia (lack of blood), infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between AFF 10mg/160mg/5mg Tablet and Fluorouracil, you can take these medicines together if prescribed by your doctor. However, if you experience diarrhoea, paleness of skin, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body pains, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet, contact your doctor.
How does the drug interact with AFF 10mg/160mg/5mg Tablet:
Combining AFF 10mg/160mg/5mg Tablet with darunavir may profoundly enhance AFF 10mg/160mg/5mg Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking AFF 10mg/160mg/5mg Tablet with darunavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with AFF 10mg/160mg/5mg Tablet:
Co-administration of AFF 10mg/160mg/5mg Tablet with Clarithromycin possibly enhances AFF 10mg/160mg/5mg Tablet levels in the blood. This can raise the chance of side effects (liver damage and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with AFF 10mg/160mg/5mg Tablet if prescribed by the doctor. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinSaquinavir
Severe
How does the drug interact with AFF 10mg/160mg/5mg Tablet:
Taking AFF 10mg/160mg/5mg Tablet with saquinavir may significantly enhance AFF 10mg/160mg/5mg Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury0.

How to manage the interaction:
Co- administration of AFF 10mg/160mg/5mg Tablet with saquinavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It is best to limit or avoid alcoholic drinks while you are taking this medicine.
  • Try aromatherapy, yoga, and meditation to help relax your body and mind.
  • Try to do breathing exercises to get more oxygen.
  • Eat a healthy diet rich in soluble fibres like beans, legumes, whole grains, flax, apples, and citrus fruits.
  • Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol in a short period.
  • Foods like avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, and lower the consumption of red meat.
  • Try to prioritise more fruits and veggies in your daily meal as these contain antioxidants that help lower LDL.
  • Quitting smoking is the best strategy to lower the risk of heart disease.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS

AFF 10mg/160mg/5mg Tablet Substitute

Substitutes safety advice

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

AFF 10mg/160mg/5mg Tablet contains Atorvastatin, Fenofibrate and Folic Acid. Atorvastatin prevents your body from making "bad" cholesterol (LDL), while Fenofibrate works by lowering the levels of triglycerides in your blood. Additionally, they raise "good" cholesterol (HDL) levels. Folic Acid reduces the levels of a harmful substance (homocysteine), thereby decreasing cholesterol synthesis.

When you have more than your body requirements, cholesterol can result in plaque to build-up in your blood vessels. This thick, hard plaque can block your arteries like a blocked pipe. Decreased blood flow can cause heart attack and stroke.

Take the missed dose as soon as possible, or skip to the next dose if it's been too late. Never try to take a double dose to make up for the missed dose.

Strictly no; a patient is advised to take a proper healthy diet free of oily and fatty products recommended by the doctor for the best results of this medication.

AFF 10mg/160mg/5mg Tablet contains Atorvastatin which can raise your blood sugar a little. If you already have type 2 diabetes, please consult your doctor. Your doctor may adjust the dosage of AFF 10mg/160mg/5mg Tablet.

Drug-Drug Interactions Checker List

  • ROSUVASTATIN
  • SIMVASTATIN
  • DICUMAROL
  • WARFARIN
  • LEVOKETOCONAZOLE

Disease/Condition Glossary

High cholesterol: Cholesterol is a waxy substance produced by the liver to protect nerves, make tissue, and various hormones. Our body also receives cholesterol from food, like cooking oils, eggs, meats, and dairy products. Excess cholesterol is bad for our health. There are two types of cholesterol: ' bad cholesterol' and 'good cholesterol'. Bad cholesterol comprises low-density lipoprotein (LDL) and triglycerides (TG), while good cholesterol consists of high-density lipoprotein (HDL). Usually, there are no specific symptoms of raised or high cholesterol levels but a large deposition of cholesterol in the arteries (plaque) or heart blockage. Blocked artery or plaque formation in the heart's arteries can lead to chest pain (angina), heart attack, or stroke. So it is advisable to have complete cholesterol tests (lipid profile tests) at least once a year. It will help you closely monitor your heart health and risk of heart attack and stroke.

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