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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS
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Composition :

DABIGATRAN-110MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Afogatran 110 Capsule

Afogatran 110 Capsule belongs to a class of drugs known as anticoagulants or blood thinners used to prevent and treat the risk of stroke, and heart attack in patients with atrial fibrillation (irregular heart rhythm), reducing blood clot formation. Besides this, it is also used to prevent deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) and reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries.

Afogatran 110 Capsule contains ‘Dabigatran’, which works by inhibiting the production of clotting factors Xa called thrombin. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clot formation. It makes your blood flow easy through your veins, making it less likely to form a serious blood clot. So, an intake of Afogatran 110 Capsule helps prevent blood clots if you have an increased risk of having a heart attack, or stroke.

Take Afogatran 110 Capsule as prescribed by your doctor. You are advised to take Afogatran 110 Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience bleeding, anaemia (low number of red blood cells), and nausea, stomach pain, indigestion. Most of these side effects of Afogatran 110 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Afogatran 110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Afogatran 110 Capsule . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Afogatran 110 Capsule . Try not to stop taking this medicine of your own. Stopping a sudden intake of Afogatran 110 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke.

Uses of Afogatran 110 Capsule

Prevention of stroke, Prevention of heart attack

Directions for Use

Swallow Afogatran 110 Capsule as a whole with water; do not crush or chew it.

Medicinal Benefits

Afogatran 110 Capsule belongs to a class of drugs known as anticoagulants or blood thinner. It prevents clot formation in the deep vein thrombosis (veins of the legs), pulmonary embolism (lungs), stroke (brain), and heart in patients with atrial fibrillation (irregular heart rhythm). Afogatran 110 Capsule is primarily used to prevent and treat the risk of stroke and heart attack by reducing blood clot formation. Besides this, it also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. Afogatran 110 Capsule works by stopping the action of clotting factor (thrombin). This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Afogatran 110 Capsule

  • Stomach pain
  • Indigestion
  • Bleeding
  • Anemia (low number of red blood cells)
  • Nausea
  • Diarrhea

Drug Warnings

If you are known to be allergic to Afogatran 110 Capsule or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Afogatran 110 Capsule . Safety and effectiveness of Afogatran 110 Capsule have not been established, so its use should be avoided in pediatric patients or children less than 18 years of age. If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking Afogatran 110 Capsule . Try not to stop taking Afogatran 110 Capsule of your own. Stopping a sudden intake of Afogatran 110 Capsule may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke. Hence, you should consult a doctor before stopping the dose of Afogatran 110 Capsule . You should inform the doctor that you are taking Afogatran 110 Capsule before any surgery is scheduled. Afogatran 110 Capsule can cause a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). Avoid consumption of alcohol while taking Afogatran 110 Capsule as it may increase the risk of stomach bleeding.

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
Dabigatran etexilateKetoconazole
Severe

Drug-Drug Interactions

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Dabigatran etexilateMifepristone
Critical
How does the drug interact with Afogatran 110 Capsule:
When Mifepristone is taken with Afogatran 110 Capsule, it may increase the risk of severe vaginal bleeding in women.

How to manage the interaction:
Taking Mifepristone with Afogatran 110 Capsule is not recommended, but it can be taken if prescribed by the doctor. However, if you experience heavy, persistent vaginal bleeding, consult the door. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateKetoconazole
Severe
How does the drug interact with Afogatran 110 Capsule:
Coadministration of Ketoconazole and Afogatran 110 Capsule may increase the blood levels and effects Afogatran 110 Capsule. This may increase the risk of anemia and bleeding issues.

How to manage the interaction:
Although taking Ketoconazole and Afogatran 110 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you notice paleness, exhaustion, dizziness, fainting, unusual bleeding or bruising, swelling, nausea, vomiting, blood in your urine or stools, headache, or weakness, consult a doctor. Do not discontinue any medication without consulting a doctor.
Dabigatran etexilateFosphenytoin
Severe
How does the drug interact with Afogatran 110 Capsule:
When Afogatran 110 Capsule is taken with Fosphenytoin, it can lower the rate at which the body breaks down Afogatran 110 Capsule. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Fosphenytoin with Afogatran 110 Capsule together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms like sudden breathlessness, sharp chest pain, throbbing, cramping pain, swelling, redness or warmth in legs or arms, it's important to let your doctor know right away. They can recommend other options that won't cause any problems with your current medications. Do not discontinue any medications without first consulting your doctor.
Dabigatran etexilateLepirudin
Severe
How does the drug interact with Afogatran 110 Capsule:
Taking Afogatran 110 Capsule with Lepirudin can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Afogatran 110 Capsule with Lepirudin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateDefibrotide
Severe
How does the drug interact with Afogatran 110 Capsule:
Taking Afogatran 110 Capsule with Defibrotide can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Afogatran 110 Capsule with Defibrotide together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilatePiroxicam
Severe
How does the drug interact with Afogatran 110 Capsule:
Coadministration of Piroxicam with Afogatran 110 Capsule can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Piroxicam and Afogatran 110 Capsule, but it can be taken if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without talking to a doctor.
Dabigatran etexilatePhenobarbital
Severe
How does the drug interact with Afogatran 110 Capsule:
Phenobarbital can drastically lower Afogatran 110 Capsule blood levels, making the medicine less effective in treating and preventing blood clots.

How to manage the interaction:
Although taking phenobarbital with Afogatran 110 Capsule can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateMeloxicam
Severe
How does the drug interact with Afogatran 110 Capsule:
Co-administration of Meloxicam with Afogatran 110 Capsule together can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Afogatran 110 Capsule and Meloxicam, you can take these medicines together if prescribed by a doctor. If you notice any of these symptoms - bleeding, bruising, feeling dizzy or weak, black or tarry stools, severe headaches, or bleeding or vomiting - contact a doctor right away. Do not stop using any medications without talking to a doctor.
Dabigatran etexilateAlteplase
Severe
How does the drug interact with Afogatran 110 Capsule:
Taking Afogatran 110 Capsule with Alteplase can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Afogatran 110 Capsule with Alteplase together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
Dabigatran etexilateApixaban
Severe
How does the drug interact with Afogatran 110 Capsule:
Coadministration of Afogatran 110 Capsule and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Afogatran 110 Capsule and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.

Drug-Food Interactions

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DABIGATRAN-110MGHerbal products/medicines

Drug-Food Interactions

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DABIGATRAN-110MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort, Garlic Pill

How to manage the interaction:
Herbs and supplements may interact with Afogatran 110 Capsule. Avoid St. John's Wort, herbs including garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba during Afogatran 110 Capsule treatment.

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Afogatran 110 Capsule .
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals, and maintain a healthy diet that includes fresh fruits, vegetables.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on how to notice and manage the early symptoms of detecting heart diseases. 

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Afogatran 110 Capsule Substitute

Substitutes safety advice
  • Dabigo 110 mg Capsule 10's

    by AYUR

    14.58per tablet
  • Dabistar 110 Capsule 10's

    by AYUR

    31.55per tablet
  • Dablexa 110 Capsule 10's

    by AYUR

    32.04per tablet
  • Dabirex-110 Capsule 10's

    by AYUR

    29.79per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No, you are not recommended to stop taking Afogatran 110 Capsule without consulting your doctor to worsen the condition. Therefore, take Afogatran 110 Capsule for as long as your doctor has prescribed it.

Please consult your doctor if Afogatran 110 Capsule needs to be discontinued before undergoing surgery. The doctor might ask you to stop taking Afogatran 110 Capsule a few days before surgery since it can cause an increased risk of bleeding during surgery. It also causes a serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anaesthesia (epidural). This type of blood clot could cause long-term paralysis.

Afogatran 110 Capsule is generally safe to take for a long time. It works best if you take it for many months or even years. It is advisable, please consult your doctor and take Afogatran 110 Capsule for as long as your doctor has prescribed it.

Taking Afogatran 110 Capsule during pregnancy may cause bleeding in the mother or the newborn baby. However, please consult your doctor if you are planning to become pregnant or already pregnant before starting Afogatran 110 Capsule .

Afogatran 110 Capsule consists of Dabigatran is a blood-thinning agent and can increase the risk of bleeding. It is advised to be cautious during your daily activities like shaving, cutting fingernails, or using sharp objects. Also, please consult your doctor beforehand if you undergo any surgery.

Drug-Drug Interactions Checker List

  • WARFARIN
  • PHENPROCOUMON
  • ACENOCOUMAROL
  • HEPARIN
  • CLOPIDOGREL
  • PRASUGREL
  • TICAGRELOR
  • RIVAROXABAN
  • AMIODARONE
  • DRONEDARONE
  • QUINIDINE
  • VERAMAPIL
  • KETOCONAZOLE
  • ITRACONAZOLE
  • TACROLIMUS
  • CYCLOSPORINE
  • LOPINAVIR
  • RITONAVIR
  • GLECAPREVIR
  • PIBRENTASVIR
  • RIFAMPICIN
  • CLARITHROMYCIN
  • ASPIRIN
  • IBUPROFEN
  • DICLOFENAC
  • CARBAMAZEPINE
  • PHENYTOIN

Special Advise

You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR), and the INR, or international normalized ratio to analyze your blood clotting time.

Disease/Condition Glossary

A blood clot can occur in any part of the body that can lead to a heart attack, stroke, and damage to organs (even coma or death). Blood clots can reach your arteries or veins in the organs like the brain, kidney, heart, lungs, and limbs. Conditions like atherosclerosis, diabetes, heart failure, irregular heartbeat (arrhythmia), and obesity/overweight can trigger excessive blood clotting in the brain and heart. On the other hand, deep vein thrombosis (blood clot in veins), peripheral artery disease (narrowed arteries due to fat deposit or blood clot), and atherosclerosis (fat build upon the walls of the arteries) can cause a blood clot in your limbs.

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