Ticlopidine
About
Ticlopidine belongs to a group of medicines called platelet aggregation inhibitors used to lower the risk of stroke in those who have already experienced a stroke, have shown warning symptoms of one, or are not responding well to aspirin treatment. Stroke occurs when the blood supply to the brain is interrupted or reduced.
Ticlopidine contains Ticlopidine, which works by preventing the platelets from forming clots. Thereby, it helps reduce the formation of clots and the risk of stroke.
In some cases, Ticlopidine may cause side effects such as diarrhoea, headache, stomach pain, loss of appetite, nausea, and vomiting. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.
Let the doctor know if you are allergic to any components in Ticlopidine. Consult the doctor if you are pregnant or breastfeeding. Ticlopidine is not recommended for children as the safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.
Uses of Ticlopidine
Medicinal Benefits
Ticlopidine belongs to a group of medicines called platelet aggregation inhibitors used to reduce the risk of fatal or non-fatal thrombotic stroke in patients who have experienced warning signs of a stroke and in those who have had a complete thrombotic stroke. It may also used in combination with aspirin to prevent the formation of blood clots in coronary stents. Ticlopidine contains Ticlopidine, which works by preventing the platelets from forming clots. Thereby, it helps reduce the formation of clots and the risk of stroke.
Directions for Use
Storage
Side Effects of Ticlopidine
- Diarrhoea
- Headache
- Nausea
- Vomiting
- Stomach pain
- Loss of appetite
- Gas
In-Depth Precautions and Warning
Drug Warnings
Do not take Ticlopidine if you are allergic to any of its components; if you have hematopoietic disorders like neutropenia (low white blood cells), thrombocytopenia (low platelet count), a history of thrombotic thrombocytopenic purpura (life-threatening blood disorder), peptic ulcers, intracranial bleeding, or severe liver impairment. Inform the doctor if you have liver disease, bleeding problems, kidney disease, bleeding ulcers, high blood fats, or high blood cholesterol. Ticlopidine may cause a decrease in white blood cells; consult the doctor if you experience fever, sore throat, chills, or other signs of infection. Seek medical attention if you experience fever, anaemia, kidney abnormalities, and neurological changes; these could be the signs of a potentially life-threatening condition known as thrombotic thrombocytopenic purpura (TTP). Call your doctor immediately if you notice yellowing of the eyes or skin, pale colour, rash, fever, seizures, difficulty speaking, dark urine, or weakness on the side of the body.
Drug Interactions
Drug-Drug Interactions: Inform the doctor if you are taking antacids (cimetidine), blood thinner (warfarin, aspirin, clopidogrel), cardiac glycoside (digoxin), or xanthines (theophylline).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Inform the doctor if you have neutropenia (low white blood cells), thrombocytopenia (low platelet count), or a history of thrombotic thrombocytopenic purpura (life-threatening blood disorder), liver or kidney problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIt is unknown if alcohol interacts with Ticlopidine. Please consult the doctor.
Pregnancy
cautionTiclopidine belongs to pregnancy category B. It should be used during pregnancy only if clearly needed.
Breast Feeding
cautionIt is not known if Ticlopidine passes into breast milk. Please consult the doctor if you are breastfeeding. Your doctor will decide whether to discontinue nursing or the medicine, taking into account the importance of the medicine to the mother.
Driving
consult your doctorIt is unknown if Ticlopidine affects your ability to drive. Drive or operate machinery only if you are alert.
Liver
cautionTiclopidine may not be recommended for patients with severe liver disease. Please consult the doctor if you have a liver impairment or any concerns regarding this.
Kidney
cautionDose adjustment may be needed in patients with kidney impairment. Please consult the doctor if you have kidney impairment or any concerns regarding this.
Children
unsafeTiclopidine is not recommended for children as the safety and effectiveness have not been established.
Habit Forming
Diet & Lifestyle Advise
- Follow a low-fat, high-fibre diet.
- Avoid processed foods.
- Maintain a balanced diet. Include vegetables, fruits and whole grains.
- Limit daily salt content.
- Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
- Avoid smoking and alcohol consumption.
Special Advise
- Your doctor may advise blood tests prior to initiation of treatment and then every two weeks for the first three months to monitor blood count.
- Inform the doctor if you are due to undergo surgery, including dental surgery. The doctor may ask you to stop taking Ticlopidine 10-14 days prior to your procedure.
Patients Concern
Disease/Condition Glossary
Stroke: Stroke occurs when the blood supply to the brain is interrupted or reduced. This prevents the brain from receiving oxygen and nutrients necessary for its functioning. Lack of blood supply and oxygen to the brain leads to damaged brain cells and tissues; this causes the death of brain cells within minutes, leading to stroke. Symptoms of stroke include difficulty speaking, paralysis on one side of the body, vision problems, severe headache, confusion, numbness, and loss of coordination or balance. Stroke requires immediate medical attention to prevent brain damage, long-term disability and death.
FAQs
Ticlopidine works by preventing the platelets from forming clots. Thereby, it helps reduce the formation of clots and the risk of stroke.
Do not discontinue Ticlopidine without consulting your doctor. To treat your condition effectually, continue taking Ticlopidine for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Ticlopidine.
Consult the doctor if you are 65 years of age or older. Older adults should not usually take Ticlopidine as it is not as safe and effective as other medicines used to treat similar conditions.
Take antacids 1 hour before or 2 hours after taking Ticlopidine. However, consult the doctor before taking other medicines with Ticlopidine.
