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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Whats That

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Composition :

TIROFIBAN-5MG

Manufacturer/Marketer :

Nicholas Piramal India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About AGGRIBLOC 5MG I.V INJECTION 100ML

AGGRIBLOC 5MG I.V INJECTION 100ML belongs to a class of medicines called 'antiplatelets' (blood thinners) used to prevent blood clots. It helps to prevent heart attack and chest pain. It is intended for use with unfractionated heparin and aspirin. A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful for stopping bleeding, they are harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs.

AGGRIBLOC 5MG I.V INJECTION 100ML contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

AGGRIBLOC 5MG I.V INJECTION 100ML will be administered by a healthcare professional; do not self-administer. Sometimes, AGGRIBLOC 5MG I.V INJECTION 100ML may cause common side effects such as bleeding under the skin at the site of injection or into a muscle causing swelling, bleeding after surgery, invisible blood in stool or urine, headache or feeling sick. Most of these side effects of AGGRIBLOC 5MG I.V INJECTION 100ML do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tirofiban or any other medicines, please tell your doctor. AGGRIBLOC 5MG I.V INJECTION 100ML is not recommended for children as safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, inform your doctor before receiving AGGRIBLOC 5MG I.V INJECTION 100ML. Avoid alcohol consumption with AGGRIBLOC 5MG I.V INJECTION 100ML as it may increase the risk of bleeding in the stomach or intestines. If you have a history of stroke or bleeding internally within the last 30 days, avoid receiving AGGRIBLOC 5MG I.V INJECTION 100ML.

Uses of AGGRIBLOC 5MG I.V INJECTION 100ML

Prevent blood clots, heart attack and chest pain

Directions for Use

AGGRIBLOC 5MG I.V INJECTION 100ML will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

AGGRIBLOC 5MG I.V INJECTION 100ML contains Tirofiban, an antiplatelet which prevents platelets (blood cells) from sticking together to form blood clots. Thus, it is used to prevent blood clots. Also, it helps blood flow to the heart and prevents heart attack and chest pain. Additionally, it may be used in patients whose heart vessels are dilated with a balloon (percutaneous coronary intervention or PCI). It is intended for use with unfractionated heparin and aspirin.

Storage

Store in a cool and dry place away from sunlight

Side Effects of AGGRIBLOC 5MG I.V INJECTION 100ML

  • Bleeding under the skin at the site of injection or into a muscle causes swelling
  • Bleeding after surgery
  • Invisible blood in stool or urine
  • Headache
  • Feeling sick

Drug Warnings

If you are allergic to Tirofiban or any other medicines, please tell your doctor. AGGRIBLOC 5MG I.V INJECTION 100ML is not recommended for children as safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, inform your doctor before receiving AGGRIBLOC 5MG I.V INJECTION 100ML. Avoid alcohol consumption with AGGRIBLOC 5MG I.V INJECTION 100ML as it may increase the risk of bleeding in the stomach or intestines. If you have a history of stroke or bleeding internally within the last 30 days, avoid receiving AGGRIBLOC 5MG I.V INJECTION 100ML. If you have had cardiopulmonary resuscitation (CPR), a biopsy, or a procedure to break up kidney stones within the last 2 weeks or have been seriously injured, had a major operation or had an ulcer in the stomach or intestine within the last 3 months, had a recent spinal procedure, have history or symptoms of aortic dissection (splitting of the aorta, main artery), or had a special intravenous line inserted under your collar bone within the last 24 hours, inform your doctor before receiving AGGRIBLOC 5MG I.V INJECTION 100ML.

Drug-Drug Interactions

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TirofibanFondaparinux
Severe
TirofibanPrasugrel
Severe

Drug-Drug Interactions

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TirofibanFondaparinux
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Taking Aggribloc 5mg I.v Injection 100ml with Fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Fondaparinux and Aggribloc 5mg I.v Injection 100ml, it can be taken if your doctor has advised it. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TirofibanPrasugrel
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Co-administration of Aggribloc 5mg I.v Injection 100ml with Prasugrel can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Aggribloc 5mg I.v Injection 100ml and Prasugrel, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
TirofibanRivaroxaban
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Co-administration of Aggribloc 5mg I.v Injection 100ml and Rivaroxaban can increase the risk of bleeding problems.

How to manage the interaction:
Co-administration of Aggribloc 5mg I.v Injection 100ml and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
TirofibanApixaban
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Coadministration of Aggribloc 5mg I.v Injection 100ml and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Aggribloc 5mg I.v Injection 100ml and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.
TirofibanAspirin
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Using aspirin together with Aggribloc 5mg I.v Injection 100ml can cause you to bleed more easily.

How to manage the interaction:
Co-administration of Aspirin with Aggribloc 5mg I.v Injection 100ml can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away: bleeding, bruising, throwing up, headache, feeling dizzy, weakness, or seeing blood in your urine or stools. Do not stop using any medications without talking to a doctor.
TirofibanDasatinib
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Using dasatinib together with Aggribloc 5mg I.v Injection 100ml may increase the risk of bleeding.

How to manage the interaction:
Co-administration of Aggribloc 5mg I.v Injection 100ml with Dasatinib can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without a doctor's advice.
TirofibanClopidogrel
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Taking Clopidogrel with Aggribloc 5mg I.v Injection 100ml can make the antiplatelet effects of Aggribloc 5mg I.v Injection 100ml stronger.

How to manage the interaction:
There may be a possibility of interaction between Aggribloc 5mg I.v Injection 100ml and Clopidogrel, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting your doctor.
TirofibanDabigatran etexilate
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Taking Dabigatran etexilate with Aggribloc 5mg I.v Injection 100ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Aggribloc 5mg I.v Injection 100ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
TirofibanHeparin
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Taking Aggribloc 5mg I.v Injection 100ml with Heparin can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Heparin and Aggribloc 5mg I.v Injection 100ml, you can take these medicines together if prescribed by a doctor. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
TirofibanDeferasirox
Severe
How does the drug interact with Aggribloc 5mg I.v Injection 100ml:
Using deferasirox together with Aggribloc 5mg I.v Injection 100ml may increase the risk of gastrointestinal ulcers.

How to manage the interaction:
Co-administration of Aggribloc 5mg I.v Injection 100ml with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor to avoid medication interactions.
  • Include foods high in antioxidants, such as vegetables, fruits, olive oil, seeds, nuts, cocoa, and red wine, as they may lower the risk of developing blood clots.
  • Adopt an anti-inflammatory diet high in omega-3-rich foods, fruits and vegetables, and vitamin E-rich foods.
  • Drink plenty of fluids as dehydration can thicken blood leading to an increased risk of blood clot formation.
  • Do regular exercise as it helps to dissolve blood clots, especially in obese people.
  • Avoid alcohol consumption as it may increase the risk of bleeding.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

AGGRIBLOC 5MG I.V INJECTION 100ML Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

AGGRIBLOC 5MG I.V INJECTION 100ML contains Tirofiban, a platelet aggregation inhibitor which works by preventing platelets (blood cells) from sticking together to form blood clots. Thus, it prevents blood clot formation.

AGGRIBLOC 5MG I.V INJECTION 100ML is not recommended for patients with severe liver disease. Therefore, if you have any liver disorder, inform your doctor before receiving AGGRIBLOC 5MG I.V INJECTION 100ML.

Yes, AGGRIBLOC 5MG I.V INJECTION 100ML may cause bleeding. If you notice blood in urine or stool or coughing up blood, please inform your doctor immediately, as these might be signs of internal bleeding.

Drug-Drug Interactions Checker List

  • WARFARIN

Disease/Condition Glossary

Blood clots: A blood clot is a clump of blood that has changed from a liquid to a gel-like or semisolid state. Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs and result in serious conditions. The common risk factors for blood clots are obesity, smoking, cancer, family history of blood clots, aged over 65 years, certain birth control pills, or pregnancy. If you experience chest pressure, sudden shortness of breath, or difficulty in breathing, speaking, or seeing, please consult a doctor immediately, as these might be symptoms of blood clots. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

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